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https://www.readbyqxmd.com/read/29922857/-the-construction-and-operation-of-a-central-biomaterial-bank-the-zebanc-of-the-charit%C3%A3-berlin
#1
REVIEW
M Hummel, A Stege
The use of high-quality, well-characterized biomaterials and their clinical and demographic information for biomedical research has steadily increased in importance over the last 10 years. There are several reasons for this. On the one hand, several studies have shown that even in high-profile scientific papers the description of the origin and characteristics of the biomaterials used is missing or insufficient. On the other hand, it has become generally accepted that small collections of biomaterials are often created under ethically and legally unclear conditions without quality measures and without sufficient sustainability...
June 19, 2018: Der Pathologe
https://www.readbyqxmd.com/read/29922197/the-neural-basis-of-and-a-common-neural-circuitry-in-different-types-of-pro-social-behavior
#2
REVIEW
Jun Luo
Pro-social behaviors are voluntary behaviors that benefit other people or society as a whole, such as charitable donations, cooperation, trust, altruistic punishment, and fairness. These behaviors have been widely described through non self-interest decision-making in behavioral experimental studies and are thought to be increased by social preference motives. Importantly, recent studies using a combination of neuroimaging and brain stimulation, designed to reveal the neural mechanisms of pro-social behaviors, have found that a wide range of brain areas, specifically the prefrontal cortex, anterior insula, anterior cingulate cortex, and amygdala, are correlated or causally related with pro-social behaviors...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29915100/cardiac-implantable-electronic-device-interrogation-at-forensic-autopsy-an-underestimated-resource
#3
Philipp Lacour, Claas Buschmann, Christian Storm, Jens Nee, Abdul Shokor Parwani, Martin Huemer, Philipp Attanasio, Leif-Hendrik Boldt, Geraldine Rauch, Andreas Kucher, Burkert Pieske, Wilhelm Haverkamp, Florian Blaschke
BACKGROUND: Postmortem interrogations of cardiac implantable electronic devices (CIEDs), recommended at autopsy in suspected cases of sudden cardiac death, are rarely performed, and data on systematic postmortem CIED analysis in the forensic pathology are missing. The aim of the study was to determine whether nonselective postmortem CIED interrogations and data analysis are useful to the forensic pathologist to determine the cause, mechanism, and time of death and to detect potential CIED-related safety issues...
June 19, 2018: Circulation
https://www.readbyqxmd.com/read/29914796/convection-enhanced-delivery-for-diffuse-intrinsic-pontine-glioma-a-single-centre-dose-escalation-phase-1-trial
#4
Mark M Souweidane, Kim Kramer, Neeta Pandit-Taskar, Zhiping Zhou, Sofia Haque, Pat Zanzonico, Jorge A Carrasquillo, Serge K Lyashchenko, Sunitha B Thakur, Maria Donzelli, Ryan S Turner, Jason S Lewis, Nai-Kong V Cheung, Steven M Larson, Ira J Dunkel
BACKGROUND: Diffuse intrinsic pontine glioma is one of the deadliest central nervous system tumours of childhood, with a median overall survival of less than 12 months. Convection-enhanced delivery has been proposed as a means to efficiently deliver therapeutic agents directly into the brainstem while minimising systemic exposure and associated toxic effects. We did this study to evaluate the safety of convection-enhanced delivery of a radioimmunotherapy agent targeting the glioma-associated B7-H3 antigen in children with diffuse intrinsic pontine glioma...
June 15, 2018: Lancet Oncology
https://www.readbyqxmd.com/read/29895801/charitable-food-systems-capacity-to-address-food-insecurity-an-australian-capital-city-audit
#5
Christina M Pollard, Bruce Mackintosh, Cathy Campbell, Deborah Kerr, Andrea Begley, Jonine Jancey, Martin Caraher, Joel Berg, Sue Booth
Australian efforts to address food insecurity are delivered by a charitable food system (CFS) which fails to meet demand. The scope and nature of the CFS is unknown. This study audits the organisational capacity of the CFS within the 10.9 square kilometres of inner-city Perth, Western Australia. A desktop analysis of services and 12 face-to-face interviews with representatives from CFS organisations was conducted. All CFS organisations were not-for⁻profit and guided by humanitarian or faith-based values. The CFS comprised three indirect services (IS) sourcing, banking and/or distributing food to 15 direct services (DS) providing food to recipients...
June 12, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29874720/-research-on-mogan-mt-sanatorium-for-pulmonary-tuberculosis-in-modern-time
#6
W Zheng, Y C Li
The Mogan Mt.Sanatorium for Pulmonary Tuberculosis, founded in 1927, was the first tuberculosis sanatorium in modern China, with an initial intention of "treating and caring the diseased, not seeking profits" , and its name was then changed to Mogan Mountain Sanatorium in 1931. During the early period of Anti-Japanese War, it became an asylum for refugees and carrying out charitable rehabilitation activity.In May 1939, the Sanatorium was compelled to close because of the bombardment of Japanese aircraft, andonly formally opened in 1948 until today...
September 28, 2017: Zhonghua Yi Shi za Zhi, Chinese Journal of Medical History
https://www.readbyqxmd.com/read/29859909/association-of-preconception-serum-25-hydroxyvitamin-d-concentrations-with-livebirth-and-pregnancy-loss-a-prospective-cohort-study
#7
Sunni L Mumford, Rebecca A Garbose, Keewan Kim, Kerri Kissell, Daniel L Kuhr, Ukpebo R Omosigho, Neil J Perkins, Noya Galai, Robert M Silver, Lindsey A Sjaarda, Torie C Plowden, Enrique F Schisterman
BACKGROUND: Vitamin D deficiency during pregnancy is associated with adverse pregnancy outcomes, although the association between preconception vitamin D concentrations and livebirth is unknown. We aimed to assess the association between preconception vitamin D and pregnancy outcomes among women with proven fecundity. METHODS: We did a secondary analysis of a prospective cohort from the block-randomised, double-blind, placebo-controlled EAGeR trial. Women aged 18-40 years with one to two previous pregnancy losses were recruited from June 15, 2007, to July 15, 2011, at four clinical sites in the USA and followed up for up to six menstrual cycles while attempting pregnancy and throughout pregnancy if they conceived...
May 30, 2018: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/29846127/aml-high-serum-ferritin-at-initial-diagnosis-has-a-negative-impact-on-long-term-survival
#8
Jana Ihlow, Sophia Gross, Annabel Sick, Tanja Schneider, Anne Flörcken, Thomas Burmeister, Seval Türkmen, Renate Arnold, Bernd Dörken, Jörg Westermann
Increased serum ferritin (SF) is common in hematologic malignancies; however, its prognostic role in acute myeloid leukemia (AML) is not clearly established. We examined the impact of baseline SF on long-term survival in 137 intensively treated AML patients. Patients and baseline characteristics were retrieved from an AML database at Charité University Medical Center Berlin, Campus Virchow Clinic. After c-reactive protein (CRP)-based adjustment for inflammation, patients were grouped according to their baseline SF level...
May 30, 2018: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/29800062/clinicians-perspectives-on-providing-emergency-only-hemodialysis-to-undocumented-immigrants-a-qualitative-study
#9
Lilia Cervantes, Sara Richardson, Rajeev Raghavan, Nova Hou, Romana Hasnain-Wynia, Matthew K Wynia, Catherine Kleiner, Michel Chonchol, Allison Tong
Background: In the United States, nearly half of undocumented immigrants with end-stage kidney disease receive hemodialysis only when they are evaluated in an emergency department and are found to have life-threatening renal failure ("emergency-only hemodialysis" [EOHD]). These patients experience psychosocial distress and much higher mortality than patients receiving regularly scheduled hemodialysis, but little is known about how providing EOHD affects the clinicians involved...
May 22, 2018: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29781515/remaining-longevity-and-evidence-of-failure-of-cardiac-implantable-electrophysiology-devices-recovered-from-funeral-homes
#10
David Laslett, Ralph J Verdino, James N Kirkpatrick
BACKGROUND: Given the prohibitive cost of pacemakers and defibrillators for medically underserved patients in low-income countries, these devices are sometimes recovered from funeral homes for charitable re-implantation. Many devices are implanted near the end of the patients' lives, meaning that recovered devices from funeral homes have the potential for significant remaining longevity. METHODS: After sending letters asking funeral directors in the Philadelphia area to donate explanted pacemakers and defibrillators, 78 devices were recovered...
May 21, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29780001/automated-typing-of-red-blood-cell-and-platelet-antigens-a-whole-genome-sequencing-study
#11
William J Lane, Connie M Westhoff, Nicholas S Gleadall, Maria Aguad, Robin Smeland-Wagman, Sunitha Vege, Daimon P Simmons, Helen H Mah, Matthew S Lebo, Klaudia Walter, Nicole Soranzo, Emanuele Di Angelantonio, John Danesh, David J Roberts, Nick A Watkins, Willem H Ouwehand, Adam S Butterworth, Richard M Kaufman, Heidi L Rehm, Leslie E Silberstein, Robert C Green
BACKGROUND: There are more than 300 known red blood cell (RBC) antigens and 33 platelet antigens that differ between individuals. Sensitisation to antigens is a serious complication that can occur in prenatal medicine and after blood transfusion, particularly for patients who require multiple transfusions. Although pre-transfusion compatibility testing largely relies on serological methods, reagents are not available for many antigens. Methods based on single-nucleotide polymorphism (SNP) arrays have been used, but typing for ABO and Rh-the most important blood groups-cannot be done with SNP typing alone...
May 17, 2018: Lancet Haematology
https://www.readbyqxmd.com/read/29773120/age-specific-association-between-blood-pressure-and-vascular-and-non-vascular-chronic-diseases-in-0%C3%A2-5-million-adults-in-china-a-prospective-cohort-study
#12
Ben Lacey, Sarah Lewington, Robert Clarke, Xiang Ling Kong, Yiping Chen, Yu Guo, Ling Yang, Derrick Bennett, Fiona Bragg, Zheng Bian, Shaojie Wang, Hua Zhang, Junshi Chen, Robin G Walters, Rory Collins, Richard Peto, Liming Li, Zhengming Chen
BACKGROUND: The age-specific association between blood pressure and vascular disease has been studied mostly in high-income countries, and before the widespread use of brain imaging for diagnosis of the main stroke types (ischaemic stroke and intracerebral haemorrhage). We aimed to investigate this relationship among adults in China. METHODS: 512 891 adults (59% women) aged 30-79 years were recruited into a prospective study from ten areas of China between June 25, 2004, and July 15, 2008...
June 2018: Lancet Global Health
https://www.readbyqxmd.com/read/29773119/adiposity-and-risk-of-ischaemic-and-haemorrhagic-stroke-in-0%C3%A2-5-million-chinese-men-and-women-a-prospective-cohort-study
#13
Zhengming Chen, Andri Iona, Sarah Parish, Yiping Chen, Yu Guo, Fiona Bragg, Ling Yang, Zheng Bian, Michael V Holmes, Sarah Lewington, Ben Lacey, Ruqin Gao, Fang Liu, Zengzhi Zhang, Junshi Chen, Robin G Walters, Rory Collins, Robert Clarke, Richard Peto, Liming Li
BACKGROUND: China has high stroke rates despite the population being relatively lean. Uncertainty persists about the relevance of adiposity to risk of stroke types. We aimed to assess the associations of adiposity with incidence of stroke types and effect mediation by blood pressure in Chinese men and women. METHODS: The China Kadoorie Biobank enrolled 512 891 adults aged 30-79 years from ten areas (five urban and five rural) during 2004-08. During a median 9 years (IQR 8-10) of follow-up, 32 448 strokes (about 90% confirmed by neuroimaging) were recorded among 489 301 participants without previous cardiovascular disease...
June 2018: Lancet Global Health
https://www.readbyqxmd.com/read/29770960/interventions-for-increasing-fruit-and-vegetable-consumption-in-children-aged-five-years-and-under
#14
REVIEW
Rebecca K Hodder, Kate M O'Brien, Fiona G Stacey, Rebecca J Wyse, Tara Clinton-McHarg, Flora Tzelepis, Erica L James, Kate M Bartlem, Nicole K Nathan, Rachel Sutherland, Emma Robson, Sze Lin Yoong, Luke Wolfenden
BACKGROUND: Insufficient consumption of fruits and vegetables in childhood increases the risk of future non-communicable diseases, including cardiovascular disease. Interventions to increase consumption of fruit and vegetables, such as those focused on specific child-feeding strategies and parent nutrition education interventions in early childhood may therefore be an effective strategy in reducing this disease burden. OBJECTIVES: To assess the effectiveness, cost effectiveness and associated adverse events of interventions designed to increase the consumption of fruit, vegetables or both amongst children aged five years and under...
May 17, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29765295/incentives-for-blood-donation-a-discrete-choice-experiment-to-analyze-extrinsic-motivation
#15
Andrew Sadler, Ling Shi, Susanne Bethge, Axel Mühlbacher
Background: Demographic trends affect size and age structure of populations. One of the consequences will be an increasing need for blood products to treat age-related diseases. Donation services rely on voluntariness and charitable motivation. It might be questioned whether there will be sufficient blood supply with voluntary donation. The present study focused on elicitation of preferences for incentives and aimed to contribute to the discussion on how to increase donation rates. Methods: A self-administered discrete choice experiment (DCE) was applied...
April 2018: Transfusion Medicine and Hemotherapy
https://www.readbyqxmd.com/read/29758166/does-online-technology-make-us-more-or-less-sociable-a-preliminary-review-and-call-for-research
#16
Adam Waytz, Kurt Gray
How does online technology affect sociability? Emerging evidence-much of it inconclusive-suggests a nuanced relationship between use of online technology (the Internet, social media, and virtual reality) and sociability (emotion recognition, empathy, perspective taking, and emotional intelligence). Although online technology can facilitate purely positive behavior (e.g., charitable giving) or purely negative behavior (e.g., cyberbullying), it appears to affect sociability in three ways, depending on whether it allows a deeper understanding of people's thoughts and feelings: (a) It benefits sociability when it complements already-deep offline engagement with others, (b) it impairs sociability when it supplants deeper offline engagement for superficial online engagement, and (c) it enhances sociability when deep offline engagement is otherwise difficult to attain...
May 1, 2018: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/29733730/delivery-of-cascade-screening-for-hereditary-conditions-a-scoping-review-of-the-literature
#17
Megan C Roberts, W David Dotson, Christopher S DeVore, Erica M Bednar, Deborah J Bowen, Theodore G Ganiats, Ridgely Fisk Green, Georgia M Hurst, Alisdair R Philp, Charité N Ricker, Amy C Sturm, Angela M Trepanier, Janet L Williams, Heather A Zierhut, Katherine A Wilemon, Heather Hampel
Cascade screening is the process of contacting relatives of people who have been diagnosed with certain hereditary conditions. Its purpose is to identify, inform, and manage those who are also at risk. We conducted a scoping review to obtain a broad overview of cascade screening interventions, facilitators and barriers to their use, relevant policy considerations, and future research needs. We searched for relevant peer-reviewed literature in the period 1990-2017 and reviewed 122 studies. Finally, we described 45 statutes and regulations related to the use and release of genetic information across the fifty states...
May 2018: Health Affairs
https://www.readbyqxmd.com/read/29733398/pre-pregnancy-fast-food-and-fruit-intake-is-associated-with-time-to-pregnancy
#18
Jessica A Grieger, Luke E Grzeskowiak, Tina Bianco-Miotto, Tanja Jankovic-Karasoulos, Lisa J Moran, Rebecca L Wilson, Shalem Y Leemaqz, Lucilla Poston, Lesley McCowan, Louise C Kenny, Jenny Myers, James J Walker, Robert J Norman, Gus A Dekker, Claire T Roberts
STUDY QUESTION: Is preconception dietary intake associated with reduced fecundity as measured by a longer time to pregnancy (TTP)? SUMMARY ANSWER: Lower intake of fruit and higher intake of fast food in the preconception period were both associated with a longer TTP. WHAT IS KNOWN ALREADY: Several lifestyle factors, such as smoking and obesity, have consistently been associated with a longer TTP or infertility, but the role of preconception diet in women remains poorly studied...
May 4, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29729550/time-versus-money
#19
REVIEW
Ashwani Monga, Ozum Zor
Consumers are known to spend both time and money. These two resources are often seen as economically comparable because the value of one's time can be equated to a monetary amount, such as one's wage rate. Recent research suggests that even when time and money are economically equivalent, they are psychologically different. We discuss how time (versus money) leads to decision making that is more heuristic rather than systematic, to an orientation that is more emotional rather than value-maximizing, to a thinking process that is more holistic rather than analytic, and to a mindset that is more abstract rather than concrete...
April 21, 2018: Current Opinion in Psychology
https://www.readbyqxmd.com/read/29723588/separating-the-wheat-from-the-chaff-an-evaluation-of-readability-quality-and-accuracy-of-online-health-information-for-treatment-of-peyronie-s-disease
#20
Nicholas J Bompastore, Theodore Cisu, Peter Holoch
OBJECTIVES: To characterize available information about Peyronie's disease online and evaluate its readability, quality, accuracy, and respective associations with HONcode certification and website category. METHODS: The search term "Peyronie's disease" was queried on three major search engines (Google, Bing, Yahoo) and the first 50 search results on each search engine were assessed. All websites were categorized as institutional/reference, commercial, charitable, personal/patient support, or alternative medicine, and cross-referenced with the Health on the Net (HON) Foundation...
April 30, 2018: Urology
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