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https://www.readbyqxmd.com/read/29669934/divergent-responses-to-kisspeptin-in-children-with-delayed-puberty
#1
Yee-Ming Chan, Margaret F Lippincott, Temitope O Kusa, Stephanie B Seminara
BACKGROUND: The neuropeptide kisspeptin stimulates luteinizing hormone (LH) secretion in healthy adults but not in adults with idiopathic hypogonadotropic hypogonadism. We hypothesized that, in children presenting with delayed or stalled puberty, kisspeptin would elicit LH secretion in those children found on detailed nighttime neuroendocrine profiling to have evidence of emerging reproductive endocrine function. METHODS: Eleven boys and four girls were admitted overnight to assess LH secretion at baseline, after a single intravenous bolus of kisspeptin, and after a single intravenous bolus of gonadotropin-releasing hormone (GnRH)...
April 19, 2018: JCI Insight
https://www.readbyqxmd.com/read/29659341/impediments-to-effective-altruism-the-role-of-subjective-preferences-in-charitable-giving
#2
Jonathan Z Berman, Alixandra Barasch, Emma E Levine, Deborah A Small
Charity could do the most good if every dollar donated went to causes that produced the greatest welfare gains. In line with this proposition, the effective-altruism movement seeks to provide individuals with information regarding the effectiveness of charities in hopes that they will contribute to organizations that maximize the social return of their donation. In this research, we investigated the extent to which presenting effectiveness information leads people to choose more effective charities. We found that even when effectiveness information is made easily comparable across options, it has a limited impact on choice...
April 1, 2018: Psychological Science
https://www.readbyqxmd.com/read/29649334/urinary-cgmp-predicts-major-adverse-renal-events-in-patients-with-mild-renal-impairment-and-or-diabetes-mellitus-before-exposure-to-contrast-medium
#3
Lyubov Chaykovska, Fabian Heunisch, Gina von Einem, Carl-Friedrich Hocher, Oleg Tsuprykov, Mira Pavkovic, Peter Sandner, Axel Kretschmer, Chang Chu, Saban Elitok, Johannes-Peter Stasch, Berthold Hocher
BACKGROUND: The use of iodine-based contrast agents entails the risk of contrast induced nephropathy (CIN). Radiocontrast agents elicit the third most common cause of nephropathy among hospitalized patients, accounting for 11-12% of cases. CIN is connected with clinically significant consequences, including increased morbidity, prolonged hospitalization, increased risk of complications, potential need for dialysis, and increased mortality rate. The number of in-hospital examinations using iodine-based contrast media has been significantly increasing over the last decade...
2018: PloS One
https://www.readbyqxmd.com/read/29628005/narcissism-and-self-versus-recipient-oriented-imagery-in-charitable-giving
#4
Esther Kang, Arun Lakshmanan
Prior research documents extensively that high-narcissism individuals largely tend to be self-centered and often lack empathy. This research outlines the charitable appeal types that can activate empathic responses and other-centered behaviors from high-narcissism individuals. Across four studies, we show that donors who are higher in narcissism exhibit greater charitable intentions when appealed to via imagine-self charitable appeals (as opposed to imagine-recipient types of appeals). Imagine-self appeals enable high-narcissism donors to project themselves into the recipient's situation and, in doing so, elicit greater empathy and, consequently, greater charity...
April 1, 2018: Personality & Social Psychology Bulletin
https://www.readbyqxmd.com/read/29623732/clinical-outcome-and-higher-order-aberrations-after-bilateral-implantation-of-an-extended-depth-of-focus-intraocular-lens
#5
Daniel Pilger, David Homburg, Tobias Brockmann, Necip Torun, Eckart Bertelmann, Christoph von Sonnleithner
PURPOSE: The purpose of this study was to assess the clinical outcome after a bilateral implantation of an extended depth of focus intraocular lens in comparison to a monofocal intraocular lens. SETTING: Department of Ophthalmology, Charité-Medical University Berlin, Germany. PATIENTS AND METHODS: A total of 60 eyes of 30 patients were enrolled in this prospective, single-center study. The cataract patients underwent phacoemulsification with bilateral implantation of a TECNIS® Symfony (Abbott Medical Optics, Santa Ana, CA, USA, 15 patients) or a TECNIS Monofocal ZCB00 (Abbott Medical Optics, Santa Ana, CA, USA, 15 patients)...
April 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29590314/altruistic-decisions-following-penetrating-traumatic-brain-injury
#6
Jorge Moll, Ricardo de Oliveira-Souza, Rodrigo Basilio, Ivanei Edson Bramati, Barry Gordon, Geraldine Rodríguez-Nieto, Roland Zahn, Frank Krueger, Jordan Grafman
The cerebral correlates of altruistic decisions have increasingly attracted the interest of neuroscientists. To date, investigations on the neural underpinnings of altruistic decisions have primarily been conducted in healthy adults undergoing functional neuroimaging as they engaged in decisions to punish third parties. The chief purpose of the present study was to investigate altruistic decisions following focal brain damage with a novel altruistic decision task. In contrast to studies that have focused either on altruistic punishment or donation, the Altruistic Decision Task allows players to anonymously punish or donate to 30 charitable organizations involved with salient societal issues such as abortion, nuclear energy and civil rights...
March 24, 2018: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29587526/ocular-manifestations-of-marfan-syndrome-in-children-and-adolescents
#7
Daniel J Salchow, Petra Gehle
PURPOSE: To study ocular manifestations of Marfan syndrome in children and adolescents. METHODS: Retrospective comparative cohort study on consecutive patients up to age 17 years, presenting to the interdisciplinary Marfan clinic of Charité-University Medicine Berlin over a period of 4 years. RESULTS: A total of 52 Marfan syndrome patients and 73 controls were enrolled. In Marfan syndrome eyes, the cornea was flatter (mean keratometry, 40...
March 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29571656/detection-of-major-histocompatibility-complex-molecules-in-processed-allogeneic-bone-blocks-for-use-in-alveolar-ridge-reconstruction
#8
Tobias Fretwurst, Lames M Gad, Thorsten Steinberg, Hagen Schmal, Robert Zeiser, Anna-K Amler, Katja Nelson, Brigitte Altmann
OBJECTIVES: Because processed allogenic bone blocks contain remnants of cells and other organic material, the present study examined the putative presence of major histocompatibility complex (MHC) molecules in protein extracts derived from processed allogeneic bone blocks. STUDY DESIGN: Protein content and the immunogenic potential of 3 different processed allografts (Osteograft, DIZG, Berlin, Germany; Caput femoris, DIZG, Berlin, Germany; Human Spongiosa, Charité Tissue Bank, Berlin, Germany) were assessed by protein extraction and analysis of the presence of MHC class 1 and 2 molecules prior to grafting...
March 20, 2018: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29570969/tardive-dyskinesia-recognition-patient-assessment-and-differential-diagnosis
#9
Rakesh Jain, Christoph U Correll
Tardive dyskinesia (TD) is an involuntary movement disorder associated with antipsychotic treatment. Because of the serious and potentially irreversible nature of TD, accurate diagnosis is crucial. However, diagnosing TD can be challenging, since the subtle and often fluctuating symptoms can be easily mistaken for symptoms of mental illness or other side effects. Although the risk of developing TD in relation to treatment with second-generation antipsychotics is lower than that associated with first-generation antipsychotics, the risk still exists and may be greater than once believed...
March 20, 2018: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29554690/an-innovative-program-to-support-gender-equity-and-success-in-academic-medicine-early-experiences-from-the-doris-duke-charitable-foundation-s-fund-to-retain-clinical-scientists
#10
Reshma Jagsi, Rochelle D Jones, Kent A Griffith, Kathleen T Brady, Ann J Brown, Randal D Davis, Amelia F Drake, Daniel Ford, Victoria J Fraser, Katherine E Hartmann, Judith S Hochman, Susan Girdler, Anne M Libby, Christina Mangurian, Judith G Regensteiner, Kimberly Yonkers, Sindy Escobar-Alvarez, Elizabeth R Myers
No abstract text is available yet for this article.
March 20, 2018: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29553026/the-knick-and-die-charit%C3%A3-historical-hospital-series-and-the-history-of-medicine
#11
Thomas Schlich
No abstract text is available yet for this article.
April 2018: Medical History
https://www.readbyqxmd.com/read/29551711/magnetic-resonance-cholangiogram-patterns-and-clinical-profiles-of-ketamine-related-cholangiopathy-in-drug-users
#12
Wai-Kay Seto, Siu-King Mak, Keith Chiu, Varut Vardhanabhuti, Ho-Fai Wong, Heng-Tat Leong, Paul S F Lee, Y C Ho, Chi-Kei Lee, Ka-Shing Cheung, Man-Fung Yuen, Wai K Leung
BACKGROUND: Recreational ketamine use has emerged as an important health and social issue worldwide. Although ketamine is associated with biliary tract damage, the clinical and radiological profiles of ketamine-related cholangiopathy have not been well-described. METHODS: We prospectively recruited consecutive Chinese individuals who used ketamine recreationally at least twice per month over 6 months in the past 2 years via a territory-wide community network of charitable organizations tackling substance abuse...
March 15, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/29549781/is-it-cost-beneficial-to-society-measuring-the-economic-worth-of-dental-residency-training
#13
Omar B Da'ar, Abdulaziz Alshaya
This study estimated whether continued programming of a highly specialized four-year dentistry residency training in Saudi Arabia was cost-beneficial. We utilized a purposive sampling to administer a survey to trainees in major cities. Additionally, we used publically available market information about general practitioners. We employed Benefit-Cost Analysis accounting approach as a conceptual framework. Using general practitioners as the base category, we grouped overall social analytical perspectives into resident trainees and rest of society...
February 19, 2018: Evaluation and Program Planning
https://www.readbyqxmd.com/read/29548855/smoking-and-smoking-cessation-in-relation-to-risk-of-diabetes-in-chinese-men-and-women-a-9-year-prospective-study-of-0%C3%A2-5-million-people
#14
Xin Liu, Fiona Bragg, Ling Yang, Christiana Kartsonaki, Yu Guo, Huaidong Du, Zheng Bian, Yiping Chen, Canqing Yu, Jun Lv, Kang Wang, Hua Zhang, Junshi Chen, Robert Clarke, Rory Collins, Richard Peto, Liming Li, Zhengming Chen
BACKGROUND: In developed countries, smoking is associated with increased risk of diabetes. Little is known about the association in China, where cigarette consumption has increased (first in urban, then in rural areas) relatively recently. Moreover, uncertainty remains about the effect of smoking cessation on diabetes in China and elsewhere. We aimed to assess the associations of smoking and smoking cessation with risk of incident diabetes among Chinese adults. METHODS: The prospective China Kadoorie Biobank enrolled 512 891 adults (59% women) aged 30-79 years during 2004-08 from ten diverse areas (five urban and five rural) across China...
March 13, 2018: Lancet. Public Health
https://www.readbyqxmd.com/read/29546392/tobacco-industry-promotional-strategies-targeting-american-indians-alaska-natives-and-exploiting-tribal-sovereignty
#15
Lauren K Lempert, Stanton A Glantz
Introduction: American Indians/Alaska Natives have the highest commercial tobacco use in the United States, resulting in higher tobacco-caused deaths and diseases than the general population. Some American Indians/Alaska Natives use commercial tobacco for ceremonial as well as recreational uses. Because federally-recognized Tribal lands are sovereign, they are not subject to state cigarette taxes and smokefree laws. This study analyzes tobacco industry promotional efforts specifically targeting American Indians/Alaska Natives and exploiting Tribal lands to understand appropriate policy responses in light of American Indians'/Alaska Natives' unique sovereign status and culture...
March 12, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29542172/empathy-social-media-and-directed-altruistic-living-organ-donation
#16
Greg Moorlock, Heather Draper
In this article we explore some of the ethical dimensions of using social media to increase the number of living kidney donors. Social media provides a platform for changing non-identifiable 'statistical victims' into 'real people' with whom we can identify and feel empathy: the so-called 'identifiable victim effect', which prompts charitable action. We examine three approaches to promoting kidney donation using social media which could take advantages of the identifiable victim effect: (a) institutionally organized campaigns based on historical cases aimed at promoting non-directed altruistic donation; (b) personal case-based campaigns organized by individuals aimed at promoting themselves/or someone with whom they are in a relationship as a recipient of directed donation; (c) institutionally organized personal case-based campaigns aimed at promoting specific recipients for directed donation...
March 15, 2018: Bioethics
https://www.readbyqxmd.com/read/29530176/pegasus-health-pastoral-care-programme
#17
Caroline Christie, Simon Wynn-Thomas, Bianca McKinnon
INTRODUCTION In New Zealand, 41% of general practitioners (GPs) intend to retire by 2025. Increasing workforce shortages and other stressors are putting doctors at risk of burnout, which in turn can put patients at risk of harm. Offering a range of resources can signal an organisation's commitment to physician wellness while improving patient safety and organisational stability. AIM To replace the current reactive approach to impaired doctors with a proactive system of monitoring performance with the goal of identifying problems early...
September 2017: Journal of Primary Health Care
https://www.readbyqxmd.com/read/29530141/a-model-of-multidisciplinary-professional-development-for-health-professionals-in-rural-canterbury-new-zealand
#18
Susan Bidwell, Andrea Copeland
INTRODUCTION Pegasus Health Charitable Ltd, a Christchurch Primary Health Organisation, is contracted by the Canterbury District Health Board to provide continuing professional development for primary care practitioners in the region. Rurally located health practitioners have largely been unable to participate because of the travel time and distances involved. AIM The initiative reported in this paper aimed to fill this gap by developing an accessible and high-quality multidisciplinary model of professional development for general practitioners, nurse practitioners, practice nurses and community pharmacists in rural areas of North Canterbury, New Zealand...
December 2017: Journal of Primary Health Care
https://www.readbyqxmd.com/read/29517258/the-moral-standing-of-animals-towards-a-psychology-of-speciesism
#19
Lucius Caviola, Jim A C Everett, Nadira S Faber
We introduce and investigate the philosophical concept of 'speciesism' -the assignment of different moral worth based on species membership -as a psychological construct. In five studies, using both general population samples online and student samples, we show that speciesism is a measurable, stable construct with high interpersonal differences, that goes along with a cluster of other forms of prejudice, and is able to predict real-world decision-making and behavior. In Study 1 we present the development and empirical validation of a theoretically driven Speciesism Scale, which captures individual differences in speciesist attitudes...
March 8, 2018: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/29515666/contemporary-challenges-for-specialist-nursing-in-interstitial-lung-disease
#20
REVIEW
Anne Marie Russell, Sandra Olive, Sarah Lines, Anna Murphy, Julie Hocking, Karen Newell, Helen Morris, Emma Harris, Catherine Dixon, Sarah Agnew, Geraldine Burge
The role of clinical nurse specialists (CNSs) in interstitial lung disease (ILD) is evolving in response to clinical guidelines and the growth of clinical research. The role is well established in the UK, although more ILD posts are needed to ensure supply meets clinical demand. This phenomenon is also happening across Europe. An appreciation of the similarities and differences between CNS and advanced nurse practitioners is important given the challenges in defining, developing and supporting this nursing specialisation...
March 2018: Breathe
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