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https://www.readbyqxmd.com/read/29457002/early-dietary-patterns-and-microbiota-development-still-a-way-to-go-from-descriptive-interactions-to-health-relevant-solutions
#1
REVIEW
Patricia Iozzo, Elena Sanguinetti
Early nutrition and growth in the initial years of life are important determinants of later body weight and metabolic health in humans, and the current epidemic of obesity involving children requires a better understanding of causal and protective mechanisms and components in infant foods. This review focuses on recent evidence implicating feeding modes (e.g., breast milk and formula milk) and dietary transitions toward complementary foods in the progression of microbiota maturation in children. The literature exploring body weight outcomes of microbiota changes induced by diet in early life is limited...
2018: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29451716/improving-growth-for-infants-%C3%A2-1250-grams-receiving-an-exclusive-human-milk-diet
#2
Robert K Huston, Andrea M Markell, Elizabeth A McCulley, Stuart K Gardiner, Sean L Sweeney
BACKGROUND: An exclusive human milk diet (EHM) fortified with human milk-based fortifier decreases necrotizing enterocolitis (NEC) compared to maternal milk supplemented with preterm formula and bovine fortifier (PTF). Growth has been less with EHM and also maternal milk supplemented with donor human milk and bovine fortifier (HMBF). The objective was to evaluate the effect of a standardized feeding protocol on the growth of infants ≤1250 g birth weight supported with EHM and HMBF. The effect on the incidence of NEC was also evaluated...
February 16, 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29439736/clinical-evaluation-of-two-different-protein-content-formulas-fed-to-full-term-healthy-infants-a-randomized-controlled-trial
#3
Liotto Nadia, Orsi Anna, Menis Camilla, Piemontese Pasqua, Morlacchi Laura, Condello Chiara Cristiana, Giannì Maria Lorella, Roggero Paola, Mosca Fabio
BACKGROUND: A high early protein intake is associated with rapid postnatal weight gain and altered body composition. We aimed to evaluate the safety of a low-protein formula in healthy full-term infants. METHODS: A randomized controlled trial was conducted. A total of 118 infants were randomized to receive two different protein content formulas (formula A or formula B (protein content: 1.2 vs. 1.7 g/100 mL, respectively)) for the first 4 months of life. Anthropometry and body composition by air displacement plethysmography were assessed at enrolment and at two and 4 months...
February 13, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29431474/maternal-carbamazepine-therapy-and-unusual-adverse-effects-in-a-breastfed-infant
#4
Roberto Antonucci, Laura Cuzzolin, Alessandra Manconi, Claudio Cherchi, Anna Maria Oggiano, Cristian Locci
BACKGROUND: Usually, no adverse effects are observed in breastfed infants whose mothers are treated with the anti-epileptic carbamazepine. In this article, we described unusual short-term adverse effects observed in a young infant after exposure to carbamazepine during pregnancy and lactation. CASE REPORT: A 40-day-old female infant, born at term, was admitted to the Pediatric Clinic at University of Sassari, Italy, for recurrent regurgitations and vomiting. She was breastfed since birth and her mother was under chronic carbamazepine therapy...
February 12, 2018: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/29429456/-role-of-donor-human-milk-feeding-in-preventing-nosocomial-infection-in-very-low-birth-weight-infants
#5
Hong-Juan Bi, Jing Xu, Qiu-Fen Wei
OBJECTIVE: To investigate the role of donor human milk in the prevention of nosocomial infection in very low birth weight infants. MeETHODS: A total of 105 hospitalized preterm infants with a very low birth weight were enrolled. They were classified into mother's own milk feeding group, donor human milk feeding group, and preterm formula feeding group, with 35 infants in each group. The three groups were compared in terms of incidence rates of nosocomial infection, necrotizing enterocolitis, and feeding intolerance, time to full enteral feeding, and early growth indices...
February 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29427921/development-and-validation-of-pediatrac%C3%A2-a-web-based-tool-to-track-developing-infants
#6
Renée Lajiness-O'Neill, Judith Brooks, Angela Lukomski, Stephen Schilling, Alissa Huth-Bocks, Seth Warschausky, Ana-Mercedes Flores, Casey Swick, Tristin Nyman, Tiffany Andersen, Natalie Morris, Thomas A Schmitt, Jennifer Bell-Smith, Barbara Moir, Elise K Hodges, James E Lyddy
OBJECTIVE: PediaTrac™, a 363-item web-based tool to track infant development, administered in modules of ∼40-items per sampling period, newborn (NB), 2--, 4--, 6--, 9-- and 12--months was validated. Caregivers answered demographic, medical, and environmental questions, and questions covering the sensorimotor, feeding/eating, sleep, speech/language, cognition, social-emotional, and attachment domains. METHODS: Expert Panel Reviews and Cognitive Interviews (CI) were conducted to validate the item bank...
February 6, 2018: Infant Behavior & Development
https://www.readbyqxmd.com/read/29425111/the-safety-of-lipistart-a-medium-chain-triglyceride-based-formula-in-the-dietary-treatment-of-long-chain-fatty-acid-disorders-a-phase-i-study
#7
Anita MacDonald, Rachel Webster, Matthew Whitlock, Adam Gerrard, Anne Daly, Mary Anne Preece, Sharon Evans, Catherine Ashmore, Anupam Chakrapani, Suresh Vijay, Saikat Santra
BACKGROUND: Children with long-chain fatty acid β-oxidation disorders (LCFAOD) presenting with clinical symptoms are treated with a specialist infant formula, with medium chain triglyceride (MCT) mainly replacing long chain triglyceride (LCT). It is essential that the safety and efficacy of any new specialist formula designed for LCFAOD be tested in infants and children. METHODS: In an open-label, 21-day, phase I trial, we studied the safety of a new MCT-based formula (feed 1) in six well-controlled children (three male), aged 7-13 years (median 9 years) with LCFAOD (very long chain acyl CoA dehydrogenase deficiency [VLCADD], n=2; long chain 3-hydroxyacyl CoA dehydrogenase deficiency [LCHADD], n=2; carnitine acyl carnitine translocase deficiency [CACTD], n=2)...
February 9, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29422195/practice-based-interpretation-of-ultrasound-studies-leads-the-way-to-more-effective-clinical-support-and-less-pharmaceutical-and-surgical-intervention-for-breastfeeding-infants
#8
REVIEW
Pamela Douglas, Donna Geddes
BACKGROUND: breastfeeding optimises health outcomes for both mothers and infants. Although most women want to breastfeed, they report commencing infant formula because of nipple pain, unsettled infant behaviour, and infant growth concerns. To date, existing approaches to fit and hold ('latch and positioning') have been demonstrated not to help breastfeeding outcomes, and women report widespread dissatisfaction with the quality of support and conflicting advice they receive. Breast and nipple pain, difficulty with latching and sucking, fussing at the breast, back-arching, marathon feeds, excessively frequent feeds, poor weight gain, breast refusal, and crying due to poor satiety often signal suboptimal positional instability and impaired milk transfer, but may be misdiagnosed as medical conditions...
March 2018: Midwifery
https://www.readbyqxmd.com/read/29411721/effect-of-a-galactagogue-herbal-tea-on-breast-milk-production-and-prolactin-secretion-by-mothers-of-preterm-babies
#9
E Özalkaya, Z Aslandoğdu, A Özkoral, S Topcuoğlu, G Karatekin
BACKGROUND AND OBJECTIVES: Poor breast milk production is the most frequent cause of breastfeeding failure in preterm babies. The aim of our study is to evaluate the effect of herbal tea mixture containing stinging nettle (Natal, Hipp) on breast milk production and serum prolactin levels of mothers, and weight gain of preterm babies. MATERIALS AND METHODS: We enrolled mothers and their babies who were less than 37 gestational week and less than 2000 g, fed with orogastric tube without any contraindication of enteral feeding in neonatal intensive care unit between November 2010 and June 2011...
January 2018: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29391686/effects-of-incorporating-agro-industrial-by-products-into-diet-of-new-zealand-rabbits-case-of-rebus-of-date-and-apricot-kernel-meal
#10
Achour Mennani, Rafik Arbouche, Yasmine Arbouche, Etienne Montaigne, Fodil Arbouche, Halima Saâdia Arbouche
Aim: The aim of this study was to determine the effects of incorporating the by-products complex of date and apricot on the fattening performance of the New Zealand breed of rabbits, to reduce the economic costs of the food formula. Materials and Methods: A total of 288 young New Zealand rabbits aged 35 days were divided into four equal groups each containing 72 animals and into sub-groups of 6 rabbits per cage, depending on the rate of substitution of corn by date rebus and of soybean meal by apricot kernel meal (0%, 10%, 20%, and 30%)...
December 2017: Veterinary World
https://www.readbyqxmd.com/read/29383887/-effect-of-eletroacupuncture-intervention-on-insulin-resistance-lipid-metabolic-disorder-and-expression-of-hepatic-srebp-1-c-and-fatty-acid-synthase-proteins-in-rats-with-hyperlipidemia
#11
Zhi-Xing Li, Hai-Hua Zhang, Dan-Chun Lan, Hong-Tao Zhang, Xiao-Zhuan Chen, Jian Sun
OBJECTIVE: To observe the effect of electroacupuncture(EA) of "Fenglong" (ST 40) and "Sanyinjiao" (SP 6) on lipid metabolic disorder, insulin resistance (IR) and expression of sterol regulatory element blinding protein-1 (SREBP-1) c and fatty acid synthase (FAS) proteins in the liver tissue in hyperlipidemia rats with IR, so as to reveal its mechanisms underlying improvement of IR. METHODS: Forty male SD rats were randomly divided into blank control, model, medication and EA groups (n=8 in each group)...
January 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29378053/lutein-is-differentially-deposited-across-brain-regions-following-formula-or-breast-feeding-of-infant-rhesus-macaques
#12
Sookyoung Jeon, Katherine M Ranard, Martha Neuringer, Emily E Johnson, Lauren Renner, Matthew J Kuchan, Suzette L Pereira, Elizabeth J Johnson, John W Erdman
Background: Lutein, a yellow xanthophyll, selectively accumulates in primate retina and brain. Lutein may play a critical role in neural and retinal development, but few studies have investigated the impact of dietary source on its bioaccumulation in infants. Objective: We explored the bioaccumulation of lutein in infant rhesus macaques following breastfeeding or formula-feeding. Methods: From birth to 6 mo of age, male and female rhesus macaques (Macaca mulatta) were either breastfed (BF) (n = 8), fed a formula supplemented with lutein, zeaxanthin, β-carotene, and lycopene (237, 19...
January 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29371876/-the-mum-has-to-live-with-the-decision-much-more-than-the-dad-a-qualitative-study-of-men-s-perceptions-of-their-influence-on-breastfeeding-decision-making
#13
Luke Hounsome, Sally Dowling
Background: Although breastfeeding is widely acknowledged as the normal method of infant feeding, there are large variations in rates of initiation and duration. Several factors are linked to the likelihood of breastfeeding initiation, including the influence and opinion of the child's father. There is limited research into men's perception of their influence, or if they feel it appropriate to be involved in deciding how to feed their children. The aim of this study was to investigate, using a qualitative methodology, fathers' perceptions of their influence on the decision to feed their child breastmilk or formula...
2018: International Breastfeeding Journal
https://www.readbyqxmd.com/read/29368651/early-feeding-of-larger-volumes-of-formula-milk-is-associated-with-greater-body-weight-or-overweight-in-later-infancy
#14
Junmei Huang, Zhen Zhang, Yuanjue Wu, Yan Wang, Jing Wang, Li Zhou, Zemin Ni, Liping Hao, Nianhong Yang, Xuefeng Yang
BACKGROUND: The relation between infant feeding and growth has been extensively evaluated, but studies examining the volume of formula milk consumption on infant growth are limited. This study aimed to examine the effects of early feeding of larger volumes of formula on growth and risk of overweight in later infancy. METHODS: In total, 1093 infants were studied prospectively. Milk records collected at 3 mo of age were used to define the following 3 feeding groups: breast milk feeding (BM, no formula), lower-volume formula milk feeding (LFM, <840 ml formula/d), and higher-volume formula milk feeding (HFM, ≥840 ml formula/d)...
January 24, 2018: Nutrition Journal
https://www.readbyqxmd.com/read/29368596/infant-formula-feeding-practices-and-the-role-of-advice-and-support-an-exploratory-qualitative-study
#15
Jessica Appleton, Rachel Laws, Catherine Georgina Russell, Cathrine Fowler, Karen J Campbell, Elizabeth Denney-Wilson
BACKGROUND: Infant formula feeding practices are an important consideration for obesity prevention. An infant's diet is influential on their later risk of developing overweight or obesity, yet very little is known about infant formula feeding practices. It is plausible that certain modifiable practices may put children at higher risk of developing overweight or obesity, for example how much and how often a baby is fed. Understanding how parents use infant formula and what factors may influence this practice is therefore important...
January 24, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29364933/long-term-dietary-replacement-of-fishmeal-and-fish-oil-in-diets-for-rainbow-trout-oncorhynchus-mykiss-effects-on-growth-whole-body-fatty-acids-and-intestinal-and-hepatic-gene-expression
#16
Viviana Lazzarotto, Françoise Médale, Laurence Larroquet, Geneviève Corraze
The effects of replacing fishmeal and fish oil with a plant-based diet were studied in juvenile (10g) and ongrowing (250-350g) rainbow trout from first-feeding. Feed-related differences in the intestinal and hepatic transcriptome were examined in juveniles after 7 months of feeding at 7°C. Based on microarray results obtained for juveniles, the expression of selected genes related to lipid, cholesterol and energy metabolisms, was assessed by RT-qPCR in ongrowing trout after 6 additional months of feeding at 17°C...
2018: PloS One
https://www.readbyqxmd.com/read/29359195/machine-learning-leveraging-genomes-from-metagenomes-identifies-influential-antibiotic-resistance-genes-in-the-infant-gut-microbiome
#17
Sumayah F Rahman, Matthew R Olm, Michael J Morowitz, Jillian F Banfield
Antibiotic resistance in pathogens is extensively studied, and yet little is known about how antibiotic resistance genes of typical gut bacteria influence microbiome dynamics. Here, we leveraged genomes from metagenomes to investigate how genes of the premature infant gut resistome correspond to the ability of bacteria to survive under certain environmental and clinical conditions. We found that formula feeding impacts the resistome. Random forest models corroborated by statistical tests revealed that the gut resistome of formula-fed infants is enriched in class D beta-lactamase genes...
January 2018: MSystems
https://www.readbyqxmd.com/read/29356563/oxytocin-receptor-antagonist-atosiban-in-the-threat-of-preterm-birth-does-it-have-any-effect-on-breastfeeding-in-the-term-newborn
#18
Lucía López Gómez, Miguel A Marín Gabriel, Begoña Encinas, Juan J de la Cruz Troca, Belén Rodríguez Marrodán
AIM: Oxytocin is a hormone involved in the mechanism of breastfeeding, uterine contractions, and social relationships. Atosiban (competitive oxytocin antagonist) is one of the most commonly used tocolytics for the threat of preterm labor in Europe. The aim of this study is to determinate if the administration of atosiban has any influence in the type of feeding in the term newborn at discharge. The secondary objective is to verify its effectiveness for the prevention of preterm delivery and in the possibility of applying treatment to complete lung maturation...
January 22, 2018: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/29344559/infant-feeding-regimens-and-gastrointestinal-tolerance-a-multicenter-prospective-observational-cohort-study-in-china
#19
Meng Mao, Lan Zhang, John Ge, Jian Yan, Robert Northington, Manjiang Yao, Joyce Nowacki, Nicholas P Hays
To study feeding tolerance in infants fed formula with increased sn-2 palmitate and oligofructose (sn-2+OF) in a real-world setting, healthy Chinese infants were enrolled in this 48-day observational study on their current feeding regimens: exclusively breastfed (BF; n = 147), exclusively sn-2+OF formula-fed (FF; n = 150), or mixed-fed with breast milk and sn-2+OF formula (MF; n = 163). Throughout the study, incidence (90% confidence interval) of hard stools was ≤2.1% (0.0-5.3) in FF and 0.8% (0.0-3.5) in MF, with no hard stools in BF...
2018: Global Pediatric Health
https://www.readbyqxmd.com/read/29338840/hydrogen-sulfide-provides-intestinal-protection-during-a-murine-model-of-experimental-necrotizing-enterocolitis
#20
Natalie A Drucker, Amanda R Jensen, Michael Ferkowicz, Troy A Markel
BACKGROUND: Necrotizing enterocolitis (NEC) continues to be a morbid surgical condition among preterm infants. Novel therapies for this condition are desperately needed. Hydrogen sulfide (H2S) is an endogenous gasotransmitter that has been found to have beneficial properties. We therefore hypothesized that intraperitoneal injection of various H2S donors would improve clinical outcomes, increase intestinal perfusion, and reduce intestinal injury in an experimental mouse model of necrotizing enterocolitis...
December 24, 2017: Journal of Pediatric Surgery
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