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https://www.readbyqxmd.com/read/28438574/extreme-hypertriglyceridemia-pseudohyponatremia-and-pseudoacidosis-in-a-neonate-with-lipoprotein-lipase-deficiency-due-to-segmental-uniparental-disomy
#1
Ambika P Ashraf, Anna C E Hurst, Abhimanyu Garg
Extreme hypertriglyceridemia is rare in the neonatal period. We report a neonate with lipoprotein lipase (LPL) deficiency who presented with diagnostic and management conundrum. A full-term 36-day-old female was noted to have "Pepto-Bismol like" blood when repeating a newborn screening. The initial plasma triglyceride level was 24,318 mg/dL. The laboratory tests revealed serum bicarbonate level of <5 mmol/L, sodium of 127 mmol/L, and severe anemia. There were no signs of acute distress. The point of care capillary blood testing, however, demonstrated normal serum pH (7...
April 3, 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28435477/acrodermatitis-enteropathica-in-a-pair-of-twins
#2
Abdullatif Al Rashed, Mohja Al Shehri, Feroze Kaliyadan
BACKGROUND: Acrodermatitis enteropathica (AE) is a rare autosomal recessive metabolic disorder. First described by Brandt in 1936 and was named by Danbolt. A mutation in the SLC39A4 gene on chromosome 8 q24.3 is responsible for this disorder, which encodes zinc transporter Zip4. The diagnosis is made by the clinical presentation and histopathology and laboratory tests. In this case, we reported a twin presented with a typical rash and low zinc level. To our knowledge, very few cases reported as a twin with typical acrodermatitis enteropathica presentation...
December 31, 2016: Journal of Dermatological Case Reports
https://www.readbyqxmd.com/read/28429912/growth-patterns-during-the-first-12-months-of-life-post-hoc-analysis-for-south-australian-aboriginal-and-caucasian-infants-in-a-randomised-controlled-trial-of-formula-feeding
#3
Karen Hawke, Jennie Louise, Carmel Collins, Shao J Zhou, Alex Brown, Robert Gibson, Maria Makrides
BACKGROUND AND OBJECTIVES: To compare growth characteristics of Aboriginal and Caucasian formula-fed in-fants in the first 12 months of life. METHODS AND STUDY DESIGN: We conducted post-hoc data analysis of infants who were part of a previous randomised controlled trial comparing infants randomly assigned to cow or goat milk-based infant formulae. Weight, height, and body composition were assessed at serial time points between study entry (~1-2 weeks of age) and 12 months...
May 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28429901/development-of-the-revised-japanese-maternal-breastfeeding-evaluation-scale-short-version
#4
Hiroko Hongo, Joseph Green, Keiko Nanishi, Masamine Jimba
BACKGROUND AND OBJECTIVES: The Japanese Maternal Breastfeeding Evaluation Scale (JMBFES) was developed in 2013 based on the original Maternal Breastfeeding Evaluation Scale (MBFES). Mothers' abilities to incorporate breastfeeding into their daily life may influence their decision to continue or discontinue to breastfeed, but that version of the JMBFES had no questions to measure this important aspect of breastfeeding. Therefore, we sought to improve the JMBFES by incorporating questions measuring "lifestyle compatibility-incompatibility," and we conducted psychometric testing of the improved version...
May 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28421711/vitamin-d-status-of-white-pregnant-women-and-infants-at-birth-and-4%C3%A2-months-in-north-west-england-a-cohort-study
#5
A J B Emmerson, K Dockery, M Z Mughal, S A Roberts, C L Tower, J L Berry
The prevalence of vitamin D deficiency in pregnant white-skinned women (WSW) and their infants has not been investigated at northern latitudes in a developed county. A 2-year observational cohort study was undertaken in the North West of England to determine 25-hydroxyvitamin D (25OHD) levels in WSW and their infants during pregnancy and 4 months postdelivery and to explore factors associated with these levels. Nutritional and lifestyle questionnaires were completed and 25OHD levels measured at 28 weeks and 4 months postdelivery...
April 18, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/28418803/an-ecological-momentary-assessment-of-primiparous-women-s-breastfeeding-behavior-and-problems-from-birth-to-8-weeks
#6
Jill R Demirci, Debra L Bogen
BACKGROUND: Primiparous women are at risk for early, unintended breastfeeding reduction and cessation. Breastfeeding patterns that contribute to these outcomes require further exploration. Research aim: This study aimed to describe early, "real-time" breastfeeding behaviors and perceived problems of primiparous women. METHODS: First-time mothers intending to exclusively breastfeed downloaded a commercial infant-feeding app during their postpartum hospitalization...
May 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/28407740/mu-opioid-receptor-and-delta-opioid-receptor-differentially-regulate-microglial-inflammatory-response-to-control-proopiomelanocortin-neuronal-apoptosis-in-the-hypothalamus-effects-of-neonatal-alcohol
#7
Pallavi Shrivastava, Miguel A Cabrera, Lucy G Chastain, Nadka I Boyadjieva, Shaima Jabbar, Tina Franklin, Dipak K Sarkar
BACKGROUND: Opioid receptors are known to control neurotransmission of various peptidergic neurons, but their potential role in regulation of microglia and neuronal cell communications is unknown. We investigated the role of mu-opioid receptors (MOR) and delta-opioid receptors (DOR) on microglia in the regulation of apoptosis in proopiomelanocortin (POMC) neurons induced by neonatal ethanol in the hypothalamus. METHODS: Neonatal rat pups were fed a milk formula containing ethanol or control diets between postnatal days 2-6...
April 14, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/28406738/comparison-of-gravity-flow-rates-between-enfit-and-legacy-feeding-tubes
#8
Manpreet S Mundi, Wanda Duellman, Lisa Epp, Jacob Davidson, Ryan T Hurt
BACKGROUND: Misconnections between enteral supplies and other access devices have led to significant morbidity and mortality. To reduce misconnections, a standard small-bore connector has been developed (International Organization for Standards 80369-8; ENFit). The full impact of transition to this connector is not known, however. METHOD: Working with major manufacturers and Food and Drug Administration, we obtained ENFit and comparative legacy tubes of variable sizes (low-profile, 14F, 18F, 20F, and 24F balloon gastrostomies)...
April 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28406437/low-glycemic-index-prototype-isomaltulose-update-of-clinical-trials
#9
REVIEW
Constanze Christin Maresch, Sebastian Friedrich Petry, Stephan Theis, Anja Bosy-Westphal, Thomas Linn
Low glycemic index diets are supposed to achieve a more beneficial effect on blood glucose control in people with diabetes mellitus and may also provide metabolic benefits for the general population. A prototype of a low-glycemic index carbohydrate is the natural occurring disaccharide isomaltulose that can be commercially produced from sucrose (beet sugar) to industrial scale. It is currently used in various food and drink applications as well as special and clinical nutrition feeds and formula diet as a food ingredient and alternative sugar...
April 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28405458/the-effect-of-double-nursing-an-alternative-nursing-strategy-for-the-hyper-prolific-sow-herd-on-herd-performance
#10
Manon A M Houben, Tijs J Tobias, Manon M C Holstege
BACKGROUND: Hyper-prolific sows produce more piglets than they can suckle, as the number of milk producing teats of the sow is lower (twelve to sixteen) than the number of live born piglets per litter. Farmers and farm workers are struggling to feed this surplus of piglets. To minimize suckling piglet mortality, litter size at 24 hours after parturition should not exceed the number of functional teats of the sow. Strategies to adequately nurse or feed the surplus of piglets after 24 hours are limited and mostly restricted to either fostering piglets by other sows, supplying milk replacers (formula) or early weaning and rearing on formula...
2017: Porcine Health Management
https://www.readbyqxmd.com/read/28404014/incidence-and-enteral-feed-antecedents-of-severe-neonatal-necrotising-enterocolitis-across-neonatal-networks-in-england-2012-13-a-whole-population-surveillance-study
#11
Cheryl Battersby, Nick Longford, Sundhiya Mandalia, Kate Costeloe, Neena Modi
BACKGROUND: Necrotising enterocolitis is a neonatal gastrointestinal inflammatory disease with high mortality and severe morbidity. This disorder is growing in global relevance as birth rates and survival of babies with low gestational age improve. Population data are scant and pathogenesis is incompletely understood, but enteral feed exposures are believed to affect risk. We aimed to quantify the national incidence of severe necrotising enterocolitis, describe variation across neonatal networks, and investigate enteral feeding-related antecedents of severe necrotising enterocolitis...
January 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28403572/development-and-application-of-a-probabilistic-risk-benefit-assessment-model-for-infant-feeding-integrating-microbiological-nutritional-and-chemical-components
#12
Géraldine Boué, Enda Cummins, Sandrine Guillou, Jean-Philippe Antignac, Bruno Le Bizec, Jeanne-Marie Membré
A probabilistic and interdisciplinary risk-benefit assessment (RBA) model integrating microbiological, nutritional, and chemical components was developed for infant milk, with the objective of predicting the health impact of different scenarios of consumption. Infant feeding is a particular concern of interest in RBA as breast milk and powder infant formula have both been associated with risks and benefits related to chemicals, bacteria, and nutrients, hence the model considers these three facets. Cronobacter sakazakii, dioxin-like polychlorinated biphenyls (dl-PCB), and docosahexaenoic acid (DHA) were three risk/benefit factors selected as key issues in microbiology, chemistry, and nutrition, respectively...
April 12, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28400946/the-state-of-asthma-epidemiology-an-overview-of-systematic-reviews-and-their-quality
#13
Jon Genuneit, Annina M Seibold, Christian J Apfelbacher, George N Konstantinou, Jennifer J Koplin, Stefania La Grutta, Kirsty Logan, Carsten Flohr, Michael R Perkin
BACKGROUND: Recently, we have published an overview of systematic reviews in allergy epidemiology and identified asthma as the most commonly reviewed allergic disease. Building on this work, we aimed to investigate the quality of systematic reviews in asthma using the AMSTAR checklist and to provide a reference for future, more in-depth assessment of the extent of previous knowledge. METHODS: We included all 307 systematic reviews indexed with asthma, including occupational asthma, and/or wheeze from our previous search in PubMed and EMBASE up to December 2014 for systematic reviews on epidemiological research on allergic diseases...
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/28395844/effect-of-co-trimoxazole-on-mortality-in-hiv-exposed-but-uninfected-children-in-botswana-the-mpepu-study-a-double-blind-randomised-placebo-controlled-trial
#14
Shahin Lockman, Michael Hughes, Kate Powis, Gbolahan Ajibola, Kara Bennett, Sikhulile Moyo, Erik van Widenfelt, Jean Leidner, Kenneth McIntosh, Loeto Mazhani, Joseph Makhema, Max Essex, Roger Shapiro
BACKGROUND: Co-trimoxazole prophylaxis reduces mortality among HIV-infected children, but efficacy in HIV-exposed but uninfected (HEU) children in a non-malarial, low-breastfeeding setting with a low risk of mother-to-child transmission of HIV is unclear. METHODS: HEU children in Botswana were randomly assigned to receive co-trimoxazole (100 mg/20 mg once daily until age 6 months and 200 mg/40 mg once daily thereafter) or placebo from age 14-34 days to age 15 months...
May 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28391117/delivery-and-feeding-mode-affects-fecal-calprotectin-levels-in-infants-7months-old
#15
Yoo Mi Lee, Chae-Yeon Min, You Jin Choi, Su Jin Jeong
BACKGROUND: Elevated fecal calprotectin (FC) is a non-invasive marker of inflammation indicating bowel disease. However, healthy infants have displayed high FC levels, with large variation. We sought to determine what factors might affect FC levels in children <6months old. METHODS: We recruited 133 healthy infants aged 0-6months from four Korean day care centers. Stool samples were analyzed by immunosorbent assay. All infants completed a questionnaire related to clinical characteristics including birth and feeding history...
April 6, 2017: Early Human Development
https://www.readbyqxmd.com/read/28386951/neonatal-characteristics-and-perinatal-complications-in-neonates-with-down-syndrome
#16
Zivanit Ergaz-Shaltiel, Offra Engel, Ira Erlichman, Yaron Naveh, Michael S Schimmel, Ariel Tenenbaum
The annual rate of Down syndrome (DS) births in Jerusalem is stable, regardless of prenatal screening, and diagnostic measures. We aimed to evaluate our historical cohort for obstetrical characteristics and the neonatal course and complications. We reviewed computerized medical files of neonates with the diagnosis of DS born in the four main hospitals in Jerusalem between the years 2000 and 2010 and evaluated for maternal history and primary neonatal hospitalization. A total of 403 neonates were diagnosed with DS...
April 6, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28379925/medically-graded-honey-supplementation-formula-to-preterm-infants-as-a-prebiotic-a-randomized-controlled-trial
#17
Hany Aly, Reem N Said, Iman E Wali, Amany Elwakkad, Yssra Soliman, Alaa Reda Awad, Mahmoud A Shawky, Mohamed A Mohamed
OBJECTIVES: To assess the effect of medically-graded enteral honey supplementation on the intestinal microbiota, immune response, and somatic growth of preterm infants. METHODS: A prospective randomized controlled trial was conducted on preterm infants with gestational age ≤ 34 weeks and postnatal age > 3 days. After reaching 1/2 goal enteral feeds, medically-graded bee honey was added to milk at a dose of 5, 10, 15, and 0 g/day for two weeks in groups A, B, C and D respectively...
April 5, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28365239/breastfeeding-initiation-for-aboriginal-and-torres-strait-islander-women-in-victoria-analysis-of-routinely-collected-population-based-data
#18
Helen L McLachlan, Touran Shafiei, Della A Forster
BACKGROUND: Increasing breastfeeding rates is one way of improving the short and long term health of Aboriginal and Torres Strait Islander children (hereafter referred to as Aboriginal). Despite the benefits of breastfeeding and recommendations for strategies to increase breastfeeding among Aboriginal people, there is a lack of available population data. AIM: To use population-based data from Victoria, Australia to compare breastfeeding initiation for Aboriginal and non-Aboriginal women and to explore factors associated with breastfeeding initiation of Aboriginal women...
March 29, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/28363110/-i-was-told-not-to-do-it-but%C3%A2-infant-feeding-practices-amongst-hiv-positive-women-in-southern-thailand
#19
Dusanee Suwankhong, Pranee Liamputtong
BACKGROUND AND OBJECTIVES: mothers living with HIV are encouraged not to breastfeed as it can transmit HIV to their infants. However, there is little known about how Thai women with HIV perceive and experience their infant feeding practices. This paper explores the breastfeeding experiences among Thai women living with HIV in southern Thailand. METHODS: semi-structured interviews and drawing methods were used with 30 HIV-positive women in rural communities of southern Thailand...
March 14, 2017: Midwifery
https://www.readbyqxmd.com/read/28362574/enteral-feeding-set-handling-techniques
#20
Beth Lyman, Maria Williams, Janet Sollazzo, Ashley Hayden, Pam Hensley, Hongying Dai, Cristine Roberts
BACKGROUND: Enteral nutrition therapy is common practice in pediatric clinical settings. Often patients will receive a pump-assisted bolus feeding over 30 minutes several times per day using the same enteral feeding set (EFS). This study aims to determine the safest and most efficacious way to handle the EFS between feedings. METHODS: Three EFS handling techniques were compared through simulation for bacterial growth, nursing time, and supply costs: (1) rinsing the EFS with sterile water after each feeding, (2) refrigerating the EFS between feedings, and (3) using a ready-to-hang (RTH) product maintained at room temperature...
April 2017: Nutrition in Clinical Practice
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