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https://www.readbyqxmd.com/read/28530768/perioperative-management-of-rheumatoid-medications-in-orthopedic-surgery
#1
Kunal Sindhu, Brian Cohen, Joseph A Gil
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disorder known to cause progressive joint destruction. Over time, untreated RA can lead to pain and increasing disability, making orthopedic intervention necessary. The treatment of RA revolves around a variety of medications that blunt the overall immune response. However, this may increase the risk of infection and impair wound healing. Given the nature of this disease, orthopedists frequently encounter patients with RA in the operative setting. To optimize surgical outcomes, orthopedists must carefully manage and pay special attention to the adverse side effects of the complicated medication regimens of these patients perioperatively...
May 20, 2017: Orthopedics
https://www.readbyqxmd.com/read/28527519/-adult-intramedullary-gliomas
#2
C Campello, F Parker, S Slimani, A Le Floch, A Herbrecht, N Aghakhani, C Lacroix, H Loiseau, J P Lejeune, G Perrin, J Honnorat, H Dufour, O Chinot, D Figarella, L Bauchet, H Duffau, M Lonjon, P Labauge, M Messerer, J P Daures, P Fabbro, B Ducot
OBJECTIVES: Intramedullary gliomas are rare tumors accounting for less than 4% of all primary central nervous system tumors. The aims of this retrospective multicenter study were to assess their natural outcome as well as management. METHODS AND MATERIALS: We studied 332 patients from 1984 to 2011. Histopathological examination revealed 72% ependymomas (94% were low grade tumors), 24% astrocytomas (29% were high grade tumors), 2.4% mixed gliomas and 1.7% oligodendrogliomas...
May 17, 2017: Neuro-Chirurgie
https://www.readbyqxmd.com/read/28524910/cancer-related-pain-assessment-monitoring-the-effectiveness-of-interventions
#3
Eva Gallagher, Barbara B Rogers, Jeannine M Brant
BACKGROUND: Cancer-related pain is a major health problem because of its magnitude, the subjective nature of the pain experience, and the complexity of the disease, making it difficult to assess and control. When assessment is not performed, poor pain control can result.
. OBJECTIVES: This article provides an overview of the components of a comprehensive cancer pain assessment.
. METHODS: A review of the healthcare literature was performed...
June 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28513067/interventions-for-cutaneous-molluscum-contagiosum
#4
REVIEW
Johannes C van der Wouden, Renske van der Sande, Emma J Kruithof, Annet Sollie, Lisette Wa van Suijlekom-Smit, Sander Koning
BACKGROUND: Molluscum contagiosum is a common skin infection that is caused by a pox virus and occurs mainly in children. The infection usually resolves within months in people without immune deficiency, but treatment may be preferred for social and cosmetic reasons or to avoid spreading the infection. A clear evidence base supporting the various treatments is lacking.This is an update of a Cochrane Review first published in 2006, and updated previously in 2009. OBJECTIVES: To assess the effects of specific treatments and management strategies, including waiting for natural resolution, for cutaneous, non-genital molluscum contagiosum in people without immune deficiency...
May 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28506778/genetic-factors-explain-the-association-between-pain-catastrophizing-and-chronic-widespread-pain
#5
Soshiro Ogata, Frances Williams, Andrea Burri
This study aimed to clarify whether there are shared genetic and/or environmental factors explaining the strong link between pain catastrophizing (PC) and chronic widespread pain (CWP). Data were available for N = 1,109 female twins from TwinsUK. Information on self-reported CWP and PC was subject to variance component twin analysis. Heritabilities were 40% for PC and 77% for CWP. The genetic correlation between PC and CWP was rG = 0.40%, while no evidence of an environmental correlation could be detected (rE = 0...
May 12, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28506406/adrenal-ganglioneuroma-the-padua-endocrine-surgery-unit-experience
#6
Maurizio Iacobone, Francesca Torresan, Marilisa Citton, Donatella Schiavone, Giovanni Viel, Gennaro Favia
BACKGROUND: Adrenal ganglioneuroma (AGN) is a rare tumor that originates from the gangliar cells of the sympathetic nervous system. It represents less than 5% of all adrenal masses. AGN occurs as a large mass, with benign behavior and no relevant symptoms and hormonal secretion, but it is often misdiagnosed because the preoperative radiological diagnosis is generally challenging. The aim of the present paper is to report the experience of a tertiary referral academic center regarding the management of AGN and review the relevant literature...
May 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28503221/management-of-musculoskeletal-pain-in-retail-drug-outlets-within-a-nigerian-community-a-descriptive-study
#7
Samirah N Abdu-Aguye, Aishatu Shehu, Ubaidullah I Ahmad
OBJECTIVE: This work aimed to describe attitudes and practices of both community pharmacies and patent and proprietary medicine vendor (PPMV) outlets towards over-the-counter (OTC) analgesic use for musculoskeletal pain states within Zaria, Nigeria. METHODS: The study was carried out in 2 phases from May to August 2016. Phase one was a cross-sectional survey of 40 retail drug outlets (10 community pharmacies and 30 PPMVs). A simulated patient scenario of a young adult male complaining of acute onset back pain was used to collect data on the type and quality of analgesic recommended, duration of consultation, as well as nature of information provided during the drug dispensing process...
January 2017: Pharmacy Practice
https://www.readbyqxmd.com/read/28500651/predictors-of-response-in-emergency-department-patients-receiving-intravenous-opioids-for-severe-pain
#8
Jacob A Radcliff, Rachel M Rafeq, Jane F Bowen, Laura Pontiggia, Sanchita Sen
OBJECTIVE: The primary objective of this study was to identify significant environmental and patient characteristics of emergency department (ED) patients who responded to intravenous (IV) hydromorphone and IV morphine for severe pain. Secondary objectives were to 1) investigate the individual effect of the significant environmental and patient characteristics of responders and 2) assess the nature and strength of the correlation of initial dose and change in pain score from arrival to pre-administration...
May 13, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28493422/differences-in-presentation-progression-and-rates-of-arthroplasty-between-hip-and-knee-osteoarthritis-observations-from-an-osteoarthritis-cohort-study-a-clear-role-for-conservative-management
#9
Chamila Dabare, Kim Le Marshall, Albert Leung, Caroline J Page, Peter F Choong, Keith K Lim
AIM: To describe the natural progression and the rates of arthroplasty of a cohort of hip and knee osteoarthritis (OA) patients. METHODS: An observational study of 247 consecutive patients who attended an OA clinic between May 2008 and August 2009. Follow-up survey was conducted from July 2014 to December 2014, with the primary end point being joint replacement surgery. RESULTS: One hundred and sixty-seven patients had knee OA and 80 patients had hip OA...
May 10, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28491147/a-clinical-guide-to-the-management-of-genitourinary-symptoms-in-breast-cancer-survivors-on-endocrine-therapy
#10
REVIEW
Mariana S Sousa, Michelle Peate, Sherin Jarvis, Martha Hickey, Michael Friedlander
There is increasing attention and concern about managing the adverse effects of adjuvant endocrine therapy for women with early breast cancer as the side effects of therapy influence compliance and can impair quality of life (QoL). Most side effects associated with tamoxifen (TAM) and aromatase inhibitors (AIs) are directly related to estrogen deprivation, and the symptoms are similar to those experienced during natural menopause but appear to be more severe than that seen in the general population. Prolonged estrogen deprivation may lead to atrophy of the vulva, vagina, lower urinary tract and supporting pelvic structures, resulting in a range of genitourinary symptoms that can in turn lead to pain, discomfort, impairment of sexual function and negatively impact on multiple domains of QoL...
April 2017: Therapeutic Advances in Medical Oncology
https://www.readbyqxmd.com/read/28489477/combined-sciatic-and-lumbar-plexus-nerve-blocks-for-the-analgesic-management-of-hip-arthroscopy-procedures-a-retrospective-review
#11
J Douglas Jaffe, Theodore Ross Morgan, Gregory B Russell
Hip arthroscopy is a minimally invasive alternative to open hip surgery. Despite its minimally invasive nature, there can still be significant reported pain following these procedures. The impact of combined sciatic and lumbar plexus nerve blocks on postoperative pain scores and opioid consumption in patients undergoing hip arthroscopy was investigated. A retrospective analysis of 176 patients revealed that compared with patients with no preoperative peripheral nerve block, significant reductions in pain scores to 24 hours were reported and decreased opioid consumption during the post anesthesia care unit (PACU) stay was recorded; no significant differences in opioid consumption out to 24 hours were discovered...
May 10, 2017: Journal of Pain & Palliative Care Pharmacotherapy
https://www.readbyqxmd.com/read/28480126/the-life-process-of-children-who-survived-the-manjil-earthquake-a-decaying-or-renewing-process
#12
Abbas Shamsalinia, Fatemeh Ghaffari, Nahid Dehghan-Nayeri, Sarieh Poortaghi
INTRODUCTION: Among earthquake survivors, children are more vulnerable than other age groups due to their exposure to harrowing scenes of devastation as well as their drastically new living situations that result from an earthquake disaster. The life process of children survivors undergoes many different changes that are affected by a wide range of factors. Understanding the life process of these children may lead to effective outcomes and interventions. In addition, observing children survivors establishes knowledge and understanding of the challenges that correspond with earthquake disasters...
April 4, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28465612/incidence-worsening-and-risk-factors-of-daytime-sleepiness-in-a-population-based-5-year-longitudinal-study
#13
I Jaussent, C M Morin, H Ivers, Y Dauvilliers
Excessive daytime sleepiness (EDS) is highly prevalent in the general population; however little is known about its evolution and predictors. Our objectives were to document its natural history, provide estimates of its prevalence, incidence and persistence rates, and to identify predictors of increased daytime sleepiness (DS) in a longitudinal community study of 2157 adults over 5 years. Participants completed postal assessment at baseline and at each yearly follow-up. DS was evaluated by the Epworth Sleepiness scale (ESS)...
May 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28438745/management-of-chronic-pain-using-complementary-and-integrative-medicine
#14
REVIEW
Lucy Chen, Andreas Michalsen
Complementary and integrative medicine (CIM) encompasses both Western-style medicine and complementary health approaches as a new combined approach to treat a variety of clinical conditions. Chronic pain is the leading indication for use of CIM, and about 33% of adults and 12% of children in the US have used it in this context. Although advances have been made in treatments for chronic pain, it remains inadequately controlled for many people. Adverse effects and complications of analgesic drugs, such as addiction, kidney failure, and gastrointestinal bleeding, also limit their use...
April 24, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28433976/isolated-duodenal-rupture-primary-repair-without-diversion-is-it-safe-review-of-literature
#15
Muwaffaq Mezeil Telfah
Isolated duodenal rupture is a rare injury encountered among children following blunt abdominal trauma. Early diagnosis and treatment are essential to decrease the associated morbidity and mortality. The debate is about the optimum operative management. We report a 6-year-old child who presented with acute abdominal pain due to isolated duodenal injury following blunt abdominal trauma. Emergency laparotomy revealed duodenal rupture at the junction of the first and second part of duodenum and absence of any other visceral injuries...
April 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28420379/distribution-and-symmetrical-patellofemoral-pain-patterns-as-revealed-by-high-resolution-3d-body-mapping-a-cross-sectional-study
#16
S A Boudreau, E N Kamavuako, M S Rathleff
BACKGROUND: Detailed pain mapping of extent and distribution in individuals with patellofemoral pain (PFP) within and around a complex structure such as the knee has yet to be explored. METHODS: Perceptions of on-going pain from adolescents and young adults (N = 35) with long-standing (>10 months) PFP were collected on high-resolution 3D digital body-schema of the knees. Location, area of pain, pain intensity, laterality, worse side of knee pain, symptom duration, and symmetry in bilateral knee pain were recorded...
April 18, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28420009/temporal-summation-and-motor-function-modulation-during-repeated-jaw-movements-in-patients-with-temporomandibular-disorder-pain-and-healthy-controls
#17
Yuanxiu Zhang, Sheng Shao, Jinglu Zhang, Lin Wang, Kelun Wang, Peter Svensson
Temporal summation of nociceptive inputs may be an important pathophysiological mechanism in temporomandibular disorders (TMD) pain; however, it remains unknown how natural jaw function relates to underlying pain mechanisms. This study evaluated changes in pain and movement patterns during repeated jaw movements in patients with painful temporomandibular joints (TMJ) compared with healthy controls. Twenty patients with TMD with TMJ pain, and an anterior disk displacement without reduction and 20 age- and gender-matched healthy volunteers were included...
March 31, 2017: Pain
https://www.readbyqxmd.com/read/28395516/nanotechnology-application-for-pain-therapy
#18
Mahmoud Reza Moradkhani, Arash Karimi, Babak Negahdari
Prolonged delivery of analgesic drugs at target sites remains a critical issue for efficient pain management. The use of nano-carriers has been reported to facilitate applicable delivery of these agents to target sites with a reduced level of systemic toxicity. Different analgesics have been loaded onto various nano carriers, including those that are natural, synthetic and copolymer, for various medical applications. In this review, we will discuss the concept of nano-formulated carriers for analgesic drugs and their impacts on the field of pain management...
April 10, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28392188/the-impact-of-lameness-on-welfare-of-the-dairy-cow
#19
REVIEW
Helen Rebecca Whay, Jan K Shearer
The five freedoms offer a framework for discussion of lameness and its impact on the welfare of cows. Altered feeding behavior is a cause of reduced body condition, smaller digital cushion, and lameness. Providing a comfortable environment is critical to recovery and welfare. Pain associated with injury or disease of feet or legs is manifested by lameness. Pain management is an important part of therapy. In cases of severe lameness, euthanasia may be preferred. Lameness interferes with an animal's ability to exhibit natural behaviors by altering lying time, social interaction, ovarian activity and estrus intensity, and rumination behavior...
April 6, 2017: Veterinary Clinics of North America. Food Animal Practice
https://www.readbyqxmd.com/read/28391486/etiology-pathophysiology-and-biomarkers-of-interstitial-cystitis-painful-bladder-syndrome
#20
REVIEW
Sourav Sanchit Patnaik, Antonio Simone Laganà, Salvatore Giovanni Vitale, Salvatore Butticè, Marco Noventa, Salvatore Gizzo, Gaetano Valenti, Agnese Maria Chiara Rapisarda, Valentina Lucia La Rosa, Carlo Magno, Onofrio Triolo, Vani Dandolu
PURPOSE: Interstitial cystitis/painful bladder syndrome (IC/PBS) is a chronic pain syndrome and a chronic inflammatory condition prevalent in women that leads to urgency, sleep disruption, nocturia and pain in the pelvic area, to the detriment of the sufferer's quality of life. The aim of this review is to highlight the newest diagnostic strategies and potential therapeutic techniques. METHODS: A comprehensive literature review was performed on MEDLINE, PubMed, and Cochrane databases gathering all literature about "Interstitial cystitis" and "Painful Bladder Syndrome"...
April 8, 2017: Archives of Gynecology and Obstetrics
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