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https://www.readbyqxmd.com/read/27936019/ultrasensitive-detection-of-porcine-epidemic-diarrhea-virus-from-fecal-samples-using-functionalized-nanoparticles
#1
Na Xing, Xiaoxiao Guan, Bin An, Beibei Cui, Zengguo Wang, Xiaoya Wang, Xiujuan Zhang, Qian Du, Xiaomin Zhao, Yong Huang, Dewen Tong
Porcine epidemic diarrhea virus (PEDV) is the main causative agent of porcine diarrhea, which has resulted in devastating damage to swine industry and become a perplexed global problem. PEDV infection causes lesions and clinical symptoms, and infected pigs often succumb to severe dehydration. If there is not a timely and effective method to control its infection, PEDV will spread rapidly across the whole swine farm. Therefore, preclinical identification of PEDV is of great significance for preventing the outbreak and spread of this disease...
2016: PloS One
https://www.readbyqxmd.com/read/27935574/europium-doping-of-superparamagnetic-iron-oxide-nanoparticles-enables-their-detection-by-fluorescence-microscopy-and-for-quantitative-analytics
#2
Yuske Kobayashi, Ralf Hauptmann, Harald Kratz, Monika Ebert, Susanne Wagner, Matthias Taupitz
BACKGROUND: Pharmacokinetic studies and histological detection of superparamagnetic iron oxide nanoparticles (SPIO) in biomedical research are limited due to a high iron background especially in pathological tissues. OBJECTIVE: The suitability of doping the iron oxide cores of SPIO with europium (Eu) was tested for improved histologic detection and for quantitative analysis without changing their properties as probes for magnetic resonance imaging (MRI). A special variant of SPIO, so called very small superparamagnetic iron oxide nanoparticles (VSOP), was used for this approach...
December 2, 2016: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/27934890/plasmonic-efficiencies-of-nanoparticles-made-of-metal-nitrides-tin-zrn-compared-with-gold
#3
Adrien Lalisse, Gilles Tessier, Jérome Plain, Guillaume Baffou
Metal nitrides have been proposed to replace noble metals in plasmonics for some specific applications. In particular, while titanium nitride (TiN) and zirconium nitride (ZrN) possess localized plasmon resonances very similar to gold in magnitude and wavelength, they benefit from a much higher sustainability to temperature. For this reason, they are foreseen as ideal candidates for applications in nanoplasmonics that require high material temperature under operation, such as heat assisted magnetic recording (HAMR) or thermophotovoltaics...
December 9, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27934429/-molecular-nanoclusters-a-2-nm-sized-mn29-cluster-with-a-spherical-structure
#4
Dimitris I Alexandropoulos, Adeline Fournet, Luís Cunha-Silva, George Christou, Theocharis C Stamatatos
The comproportionation reaction between Mn(II) and Mn(VII) sources in the presence of 3,3-dimethylacrylic acid and azides has led to a new {Mn29} molecular cluster with a spherical structure and dimensions of ∼2.2 nm, comparable in size to the smallest classical and magnetic nanoparticles.
December 5, 2016: Inorganic Chemistry
https://www.readbyqxmd.com/read/27934204/magneto-optical-response-of-cobalt-interacting-with-plasmonic-nanoparticle-superlattices
#5
Michael B Ross, Marc R Bourgeois, Chad A Mirkin, George C Schatz
The magneto-optical Kerr effect is a striking phenomenon whereby the optical properties of a material change under an applied magnetic field. Though promising for sensing and data storage technology, these properties are typically weak in magnitude and are inherently limited by the bulk properties of the active magnetic material. In this work, we theoretically demonstrate that plasmonic thin-film assemblies on a cobalt substrate can achieve tunable transverse magneto-optical (TMOKE) responses throughout the visible and near-infrared (300-900 nm)...
November 17, 2016: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/27934159/tailored-dual-pegylation-of-inorganic-porous-nanocarriers-for-extremely-long-blood-circulation-in-vivo
#6
Tuomo Nissinen, Simo Näkki, Hanne Laakso, Dalius Kučiauskas, Algirdas Kaupinis, Mikko I Kettunen, Timo Liimatainen, Mervi Hyvönen, Mindaugas Valius, Olli Gröhn, Vesa-Pekka Lehto
Drug carrier systems based on mesoporous inorganic nanoparticles generally face the problem of fast clearance from bloodstream thus failing in passive and active targeting to cancer tissue. To address this problem, a specific dual PEGylation (DPEG) method for mesoporous silicon (PSi) was developed and studied in vitro and in vivo. The DPEG coating changed significantly the behavior of the nanoparticles in vivo, increasing the circulation half-life from 1 to 241 min. Furthermore, accumulation of the coated particles was mainly taking place in the spleen whereas uncoated nanoparticles were rapidly deposited in the liver...
December 7, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27934080/remote-control-of-light-triggered-virotherapy
#7
S-Ja Tseng, Kuo-Yen Huang, Ivan M Kempson, Shih-Han Kao, Meng-Chia Liu, Shuenn-Chen Yang, Zi-Xian Liao, Pan-Chyr Yang
Clinical virotherapy has been successfully approved for use in cancer treatment by the U.S. Food and Drug Administration; however, a number of improvements are still sought to more broadly develop virotherapy. A particular challenge is to administer viral therapy systemically and overcome limitations in intratumoral injection, especially for complex tumors within sensitive organs. To achieve this, however, a technique is required that delivers the virus to the tumor before the body's natural self-defense eradicates the virus prematurely...
November 22, 2016: ACS Nano
https://www.readbyqxmd.com/read/27931227/epigenetics-of-amphetamine-induced-sensitization-hdac5-expression-and-microrna-in-neural-remodeling
#8
Philip K Liu, Christina H Liu
BACKGROUND: Histone deacetylase (HDAC) activities modify chromatin structure and play a role in learning and memory during developmental processes. Studies of adult mice suggest HDACs are involved in neural network remodeling in brain repair, but its function in drug addiction is less understood. We aimed to examine in vivo HDAC5 expression in a preclinical model of amphetamine-induced sensitization (AIS) of behavior. We generated specific contrast agents to measure HDAC5 levels by in vivo molecular contrast-enhanced (MCE) magnetic resonance imaging (MRI) in amphetamine-naïve mice as well as in mice with AIS...
December 8, 2016: Journal of Biomedical Science
https://www.readbyqxmd.com/read/27931160/preparation-of-hollow-core-shell-fe3o4-graphene-oxide-composites-as-magnetic-targeting-drug-nanocarriers
#9
Junmei Wang, Jianjun Fang, Pan Fang, Xian Li, Shijie Wu, Wenjing Zhang, Sufang Li
A main challenge for anticancer drugs is that the drugs can not arrive the cancer tissue at right time. In this work, a magnetic targeting nanoparticle based on hollow Fe3O4/graphene oxide (Fe3O4/GO) was developed as a potential tumor targeting drug carriers. The morphology results showed the Fe3O4 nanoparticles were uniformly wrapped by graphene oxide. After coating with graphene oxide, the Fe3O4/GO showed a higher saturation magnetization of 71.47 emu g(-1) as compared to neat Fe3O4 nanoparticles. The drug loading and releasing experiment indicated the obtained Fe3O4/GO has a good loading capacity of of 0...
December 8, 2016: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/27930297/measuring-spectroscopy-and-magnetism-of-extracted-and-intracellular-magnetosomes-using-soft-x-ray-ptychography
#10
Xiaohui Zhu, Adam P Hitchcock, Dennis A Bazylinski, Peter Denes, John Joseph, Ulysses Lins, Stefano Marchesini, Hung-Wei Shiu, Tolek Tyliszczak, David A Shapiro
Characterizing the chemistry and magnetism of magnetotactic bacteria (MTB) is an important aspect of understanding the biomineralization mechanism and function of the chains of magnetosomes (Fe3O4 nanoparticles) found in such species. Images and X-ray absorption spectra (XAS) of magnetosomes extracted from, and magnetosomes in, whole Magnetovibrio blakemorei strain MV-1 cells have been recorded using soft X-ray ptychography at the Fe 2p edge. A spatial resolution of 7 nm is demonstrated. Precursor-like and immature magnetosome phases in a whole MV-1 cell were visualized, and their Fe 2p spectra were measured...
December 7, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27928992/superspin-glass-state-in-a-diluted-nanoparticle-system-stabilized-by-interparticle-interactions-mediated-by-an-antiferromagnetic-matrix
#11
G Margaris, M Vasilakaki, D Peddis, K N Trohidou, S Laureti, C Binns, E Agostinelli, D Rinaldi, R Mathieu, D Fiorani
In nanoparticle systems consisting of two magnetic materials (bi-magnetic nanoparticles or nanoparticles embedded in a magnetic matrix), there is a constantly growing interest in the investigation of the interplay between interparticle interactions and the nanoparticle-matrix interface exchange coupling, because of its enormous impact on a number of technological applications. The understanding of the mechanisms of such interplay is a great challenge, as it would allow controlling equilibrium and non-equilibrium magnetization dynamics of exchange coupled nanoparticles systems and finely tuning their anisotropy...
December 8, 2016: Nanotechnology
https://www.readbyqxmd.com/read/27928531/a-simple-and-fast-method-based-on-new-magnetic-ion-imprinted-polymer-as-a-highly-selective-sorbent-for-preconcentration-and-determination-of-cadmium-in-environmental-samples
#12
Zahra Panjali, Ali Akbar Asgharinezhad, Homeira Ebrahimzadeh, Niloofar Jalilian, Rasoul Yarahmadi, Seyed Jamaleddin Shahtaheri
BACKGROUND: The analysis of heavy metals at trace level is one of the main toxicologists concern, due to their vital rules in human`s life. Cadmium is one of these toxic heavy metals, which released to the environment from various industries. METHODS: In order to determine Cd (II) ions in various matrices magnetic ion-imprinted polymer (IIP) method has been developed and applied. This nano-sorbent has been synthesized by coating an IIP compound on Fe3O4 nanoparticles core to achieve highest surface area...
August 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27924985/creating-bhb-imprinted-magnetic-nanoparticles-with-multiple-binding-sites
#13
Yanxia Li, Yiting Chen, Lu Huang, BenYong Lou, Guonan Chen
A kind of protein imprinted over magnetic Fe3O4@Au multifunctional nanoparticles (NPs) with multiple binding sites was synthesized and investigated. Magnetic Fe3O4@Au NPs as carrier materials were modified with 4-mercaptophenylboronic acid (MPBA) and mercaptopropionic acid (MPA) to introduce boronic acids and carboxyl groups. Using Bovine Hemoglobin (BHb) as a template, a polydopamine(PDA)-based molecular imprinted film was fabricated to produce a kind of magnetic molecularly imprinted nanoparticle (MMIP), possessing multiple binding sites with benzene-diol, amino groups, boronic acids and carboxyl groups...
December 7, 2016: Analyst
https://www.readbyqxmd.com/read/27924952/a-competitive-bio-barcode-amplification-immunoassay-for-small-molecules-based-on-nanoparticles
#14
Pengfei Du, Maojun Jin, Ge Chen, Chan Zhang, Zejun Jiang, Yanxin Zhang, Pan Zou, Yongxin She, Fen Jin, Hua Shao, Shanshan Wang, Lufei Zheng, Jing Wang
A novel detection method of small molecules, competitive bio-barcode amplification immunoassay, was developed and described in this report. Through the gold nanoparticles (AuNPs) probe and magnetic nanoparticles (MNPs) probe we prepared, only one monoclonal antibody can be used to detect small molecules. The competitive bio-barcode amplification immunoassay overcomes the obstacle that the bio-barcode assay cannot be used in small molecular detection, as two antibodies are unable to combine to one small molecule due to its small molecular structure...
December 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27924942/in-silico-before-in-vivo-how-to-predict-the-heating-efficiency-of-magnetic-nanoparticles-within-the-intracellular-space
#15
Beatriz Sanz, M Pilar Calatayud, Emilio De Biasi, Enio Lima, Marcelo Vasquez Mansilla, Roberto D Zysler, M Ricardo Ibarra, Gerardo F Goya
This work aims to demonstrate the need for in silico design via numerical simulation to produce optimal Fe3O4-based magnetic nanoparticles (MNPs) for magnetic hyperthermia by minimizing the impact of intracellular environments on heating efficiency. By including the relevant magnetic parameters, such as magnetic anisotropy and dipolar interactions, into a numerical model, the heating efficiency of as prepared colloids was preserved in the intracellular environment, providing the largest in vitro specific power absorption (SPA) values yet reported...
December 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27924296/data-in-support-of-covalent-attachment-of-tyrosinase-onto-cyanuric-chloride-crosslinked-magnetic-nanoparticles
#16
Kourosh Abdollahi, Farshad Yazdani, Reza Panahi
Preparation and characterization of cross linked amine-functionalized magnetic nanoparticles as an appropriate support for covalent immobilization on tyrosinase was presented in the study "Covalent immobilization of tyrosinase onto cyanuric chloride crosslinked amine-functionalized superparamagnetic nanoparticles: synthesis and characterization of the recyclable nanobiocatalyst" (Abdollahi et al., 2016 ) [1]. Herein, complementary data regarding X-ray powder diffraction (XRD) to characterize the synthesized magnetic nanoparticles, and transmission electron microscopy (TEM) to determine the size and morphology of tyrosinase immobilized magnetic nanoparticles (tyrosinase-MNPs) were reported...
December 2016: Data in Brief
https://www.readbyqxmd.com/read/27924295/dataset-on-the-physical-characterization-of-biopolymer-coated-magnetic-nanoparticles
#17
Shazia Bano, Muhammad Afzal
The data presented in this article is related to the research article entitled "Paclitaxel loaded magnetic nanocomposites with folate modified chitosan/carboxymethyl surface; a vehicle for imaging and targeted drug delivery" (S. Bano, M. Afzal, M.M. Waraich, K. Alamgir, S. Nazir, 2016) [1]. It contains the absorbance spectra, band gap energies of pure nickel-ferrite nano cores (NFs), and calibration curve of Paclitaxel. Thermal stability analysis of pure NFs, chitosan (CS) and carboxymethyl cellulose (CMC)-conjugated NFs samples is also included in the data...
December 2016: Data in Brief
https://www.readbyqxmd.com/read/27924220/silica-coated-magnetite-nanoparticles-core-shell-spheres-fe3o4-sio2-for-natural-organic-matter-removal
#18
Elahe Karimi Pasandideh, Babak Kakavandi, Simin Nasseri, Amir Hossein Mahvi, Ramin Nabizadeh, Ali Esrafili, Roshanak Rezaei Kalantary
BACKGROUND: In this work, the magnetite (Fe3O4) nanoparticles (MNPs) and silica-coated magnetite nanoparticles (SMNPs) were synthesized as adsorbents for removing humic acid (HA) from water resources. METHODS: The adsorption processes were performed in batch experiments with which the influence of pH, reaction time, adsorbent dosage, initial concentrations of HA and temperature were investigated. Specific techniques were applied to characterize the features of both adsorbents (i...
2016: Journal of Environmental Health Science & Engineering
https://www.readbyqxmd.com/read/27923991/a-specific-dna-nanoprobe-for-tracking-the-activities-of-human-apurinic-apyrimidinic-endonuclease-1-in-living-cells
#19
Junqiu Zhai, Yibin Liu, Shan Huang, Simin Fang, Meiping Zhao
Human apurinic/apyrimidinic endonuclease/redox effector factor 1 (APE1) is an essential DNA repair protein. Herein, we demonstrate that avidin-oriented abasic site-containing DNA strands (AP-DNA) on the surface of silica coated magnetic nanoparticles (SiMNP) can selectively respond to APE1 while resist the digestion by other nucleases. Mechanism studies have revealed that avidin may serve as an organizer protein and recruit APE1 to the DNA substrates on the nanoparticles via strong and specific interactions...
December 6, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27923765/better-together-strategies-based-on-magnetic-particles-and-quantum-dots-for-improved-biosensing
#20
REVIEW
Laura Moro, Mehmet Turemis, Bruna Marini, Rudy Ippodrino, Maria Teresa Giardi
Novel technologies and strategies for sensitive detection of biological responses in healthcare, food and environmental monitoring continue to be a priority. The present review focuses on bioassay development based on the simultaneous use of quantum dots and magnetic beads. Due to the outstanding characteristics of both particles for biosensing applications and the large number of publications using a combined approach, we aim to provide a comprehensive overview of the literature on different bioassays, the most recent advances and innovative strategies on the topic, together with an analysis of the main drawbacks encountered and potential solutions offered, with a special emphasis on the requirements that the transfer of technologies from the laboratory to the market will demand for future commercialization ofbiodevices...
December 3, 2016: Biotechnology Advances
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