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https://www.readbyqxmd.com/read/28719868/quantitative-meta-analytic-approaches-for-the-systematic-synthesis-of-data-and-hazard-identification-a-case-study-of-decreased-pain-sensitivity-due-to-trimethylbenzene-exposure
#1
J Allen Davis, Andrew Kraft
Traditionally, human health risk assessments have relied on qualitative approaches for hazard identification, which involves weight of evidence determinations that integrate evidence across multiple studies. Recently, the National Research Council has recommended the development of quantitative approaches for evidence integration, including the application of meta-analyses, to help summarize and evaluate the results of a systematic review. In the meta-analytic approach, a pooled effect size is calculated after consideration of multiple potential confounding factors in order to determine whether the entire database under consideration indicates a chemical is a hazard...
July 15, 2017: Environmental Research
https://www.readbyqxmd.com/read/28719767/capacity-of-commune-health-stations-in-chi-linh-district-hai-duong-province-for-prevention-and-control-of-noncommunicable-diseases
#2
Nguyen Thi Thuy Nga, Bui Thi My Anh, Nguyen Nguyen Ngoc, Dang Minh Diem, Vu Duy Kien, Tran Bich Phuong, Tran Quynh Anh, Hoang Van Minh
The primary health care system in Vietnam has been playing an important role in prevention and control of diseases. This study aimed to describe the capacity of commune health stations in Chi Linh district, Hai Duong province for prevention and control of noncommunicable diseases (NCDs). A mixed-methods (quantitative and qualitative approaches) approach was applied to collect data in 20 commune health stations. The participants, including health workers, stakeholders, and patients with NCDs, were selected for the study...
July 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28719565/burnout-in-orthopaedic-surgeons-a-challenge-for-leaders-learners-and-colleagues-aoa-critical-issues
#3
S Elizabeth Ames, James B Cowan, Keith Kenter, Sanford Emery, David Halsey
Burnout, depression, suicidal ideation, and dissatisfaction with work-life balance have been reported in all medical specialties and at all stages of medical education and practice experience. Burnout consists of progressive emotional, attitudinal, and physical exhaustion. Physicians with burnout may treat patients as objects and feel emotionally depleted. Burnout is characterized by a loss of enthusiasm for work (emotional exhaustion), feelings of cynicism (depersonalization), and a low sense of personal accomplishment...
July 19, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28719551/annulus-fibrosus-repair-using-high-density-collagen-gel-an-in-vivo-ovine-model
#4
Brenton Pennicooke, Ibrahim Hussain, Connor Berlin, Stephen R Sloan, Brandon Borde, Yu Moriguchi, Gernot Lang, Rodrigo Navarro-Ramirez, Jonathan Cheetham, Lawrence J Bonassar, Roger Härtl
STUDY DESIGN: Ovine in vivo study. OBJECTIVE: To perform lateral approach lumbar surgery in an ovine model to administer an injectable riboflavin (RF) cross-linked high-density collagen (HDC) gel and to assess its ability to mitigate intervertebral disc (IVD) degeneration after induced annulus fibrosus (AF) injury. SUMMARY OF BACKGROUND DATA: Biological-based injectable gels have shown efficacy in restoring biomechanical, radiographic, and histological parameters in IVD-injured animal models...
July 17, 2017: Spine
https://www.readbyqxmd.com/read/28719143/osteoporotic-vertebral-fracture-prevalence-varies-widely-between-radiological-assessment-methods-the-rotterdam-study
#5
L Oei, F Koromani, S J Breda, J T Schousboe, E M Clark, Jbj van Meurs, M A Ikram, J H Waarsing, Fja van Rooij, M C Zillikens, G P Krestin, Ehg Oei, F Rivadeneira
BACKGROUND: Accurate diagnosis of vertebral osteoporotic fractures is crucial for the identification of individuals at high risk of future fractures. Different methods for radiological assessment of vertebral fractures exist, but a gold standard is lacking. The aim of our study was to estimate statistical measures of agreement and prevalence of osteoporotic vertebral fractures in the population-based Rotterdam Study, across the two most commonly applied assessment methods. METHODS: The quantitative morphometry (QM) method, evaluates vertebral height loss that affects vertebral shape whereas the algorithm based qualitative (ABQ) method judges endplate integrity and includes guidelines for the differentiation of vertebral fracture and non- fracture deformities...
July 18, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28719110/benefits-of-attending-a-weekend-childhood-cancer-survivor-family-retreat
#6
Lisa Bashore, Joyce Bender
PURPOSE: To explore the long-term benefits to families of childhood cancer survivors who attended a weekend childhood cancer survivor family retreat. DESIGN: Descriptive-qualitative study including families who had attended the weekend retreat at least once but not in the past 12 months, and who attend a large pediatric hematology and oncology cancer survivorship program in Texas. METHODS: A semistructured interview guide was used during three audio-taped focus groups to explore the benefits of having attended a weekend retreat...
July 18, 2017: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/28718938/quality-control-of-ultrasound-for-fetal-biometry-results-from-the-intergrowth-21-st-project
#7
Angelo Cavallaro, Stephen T Ash, Raffaele Napolitano, Sikolia Wanyonyi, Eric O Ohuma, Malid Molloholli, Joyce Sande, Ippokratis Sarris, Christos Ioannou, Tess Norris, Vera Donadono, Maria Carvalho, Manorama Purwar, Fernando C Barros, Yasmin A Jaffer, Enrico Bertino, Ruyan Pang, Michael G Gravett, Laurent J Salomon, Julia Alison Noble, Douglas G Altman, Aris T Papageorghiou
OBJECTIVES: To assess a comprehensive package of ultrasound quality control in a large multicentre study of fetal growth - the Fetal Growth Longitudinal Study of the INTERGROWTH-21(st) Project. METHODS: We performed quality control (QC) measures on 20,313 ultrasound scan images taken prospectively from 4,321 fetuses at 14-41 weeks' gestation in eight geographical locations. At the time of each ultrasound examination, three fetal biometric variables were measured in triplicate on separately generated images: head circumference (HC), abdominal circumference (AC) and femur length (FL)...
July 18, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28718828/tobacco-harm-reduction-with-vaporised-nicotine-thrive-the-study-protocol-of-an-uncontrolled-feasibility-study-of-novel-nicotine-replacement-products-among-people-living-with-hiv-who-smoke
#8
Stephanie Bell, Judith Dean, Charles Gilks, Mark A Boyd, Lisa Fitzgerald, Allyson Mutch, Peter Baker, Graham Neilsen, Coral E Gartner
Smoking is a leading cause of morbidity and premature mortality among people living with HIV (PLHIV), who have high rates of tobacco smoking. Vaporised nicotine products (VNPs) are growing in popularity as a quit aid and harm reduction tool. However, little is known about their acceptability and use among PLHIV. Using a pragmatic, uncontrolled, mixed methods design this exploratory clinical trial aims to examine the feasibility of conducting a powered randomised clinical trial of VNPs as a smoking cessation and harm reduction intervention among vulnerable populations, such as PLHIV who smoke tobacco...
July 18, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28718759/qualitative-investigation-of-the-wellness-recovery-action-plan-in-a-uk-nhs-crisis-care-setting
#9
Michael Ashman, Vanessa Halliday, Joseph G Cunnane
Crisis theory suggests that in addition to presenting a threat to mental well-being, crises are also opportunities where successful interventions can lead to successful outcomes. UK mental health crisis teams aim to reduce hospital admission by treating people at home and by building resilience and supporting learning from crisis, yet data on repeat crisis episodes suggest this could be improved. This qualitative study sought to explore the Wellness Recovery Action Plan (WRAP) as a means of supporting resilience-building and maximising the opportunity potential of crisis...
July 2017: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/28718615/development-of-nanofiber-sponges-containing-nerve-guidance-conduit-for-peripheral-nerve-regeneration-in-vivo
#10
Binbin Sun, Zi-Fei Zhou, Tong Wu, Weiming Chen, Dawei Li, Hao Zheng, Hany El-Hamshary, Salem S Al-Deyab, Xiumei Mo, Yinxian Yu
In the study of hollow nerve guidance conduit (NGC), the dispersion of regenerated axons always confused the researchers. To address this problem, filler-containing NGC was prepared, which showed better effect in the application of nerve tissue engineering. In this study, nanofiber sponges with abundant macro-pores, high porosity, and superior compressive strength were fabricated by electrospinning and freeze-drying. Poly (l-lactic acid-co-ε-caprolactone)/silk fibroin (PLCL/SF) nanofiber sponges were used as filler to prepare three-dimensional nanofiber sponges-containing (NS-containing) NGC...
July 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28718496/-introduction-of-rapid-syphilis-and-hiv-testing-in-prenatal-care-in-colombia-qualitative-analysis
#11
María Teresa Ochoa-Manjarrés, Hernando Guillermo Gaitán-Duarte, Sidia Caicedo, Berta Gómez, Freddy Pérez
Objective: Interpret perceptions of Colombian health professionals concerning factors that obstruct and facilitate the introduction of rapid syphilis and HIV testing in prenatal care services. Methods: A qualitative study based on semi-structured interviews was carried out. A convenience sample was selected with 37 participants, who included health professionals involved in prenatal care services, programs for pregnant women, clinical laboratories, and directors of health care units or centers, as well as representatives from regional departments and the Ministry of Health...
December 2016: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28718325/collaborative-care-for-psychiatric-disorders-in-older-adults-a-systematic-review
#12
Pallavi Dham, Sarah Colman, Karen Saperson, Carrie McAiney, Lillian Lourenco, Nick Kates, Tarek K Rajji
OBJECTIVE: To evaluate the mode of implementation, clinical outcomes, cost-effectiveness, and the factors influencing uptake and sustainability of collaborative care for psychiatric disorders in older adults. DESIGN: Systematic review. SETTING: Primary care, home health care, seniors' residence, medical inpatient and outpatient. PARTICIPANTS: Studies with a mean sample age of 60 years and older. INTERVENTION: Collaborative care for psychiatric disorders...
January 1, 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/28718298/a-systematic-review-of-the-prevalence-of-comorbid-cancer-and-dementia-and-its-implications-for-cancer-related-care
#13
L McWilliams, C Farrell, G Grande, J Keady, C Swarbrick, J Yorke
OBJECTIVES: A comorbid diagnosis of cancer and dementia (cancer-dementia) may have unique implications for patient cancer-related experience. The objectives were to estimate prevalence of cancer-dementia and related experiences of people with dementia, their carers and cancer clinicians including cancer screening, diagnosis, treatment and palliative care. METHOD: Databases were searched (CINAHL, Psychinfo, Medline, Embase, BNI) using key terms such as dementia, cancer and experience...
July 18, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28718079/symptom-self-management-strategies-reported-by-adolescents-and-young-adults-with-cancer-receiving-chemotherapy
#14
Lauri A Linder, Jeanne M Erickson, Kristin Stegenga, Catherine Fiona Macpherson, Sarah Wawrzynski, Christina Wilson, Suzanne Ameringer
PURPOSE: Adolescents and young adults (AYAs) with cancer experience multiple symptoms related to their cancer and its treatment which can negatively impact their development and quality of life. An understanding of the strategies AYAs use to self-manage their symptoms is limited. This study described symptom self-management strategies reported by AYAs with cancer using an iPad-based symptom heuristics tool, the Computerized Symptom Capture Tool. METHODS: The study used a cross-sectional, descriptive design...
July 17, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28717985/basic-echocardiography-for-undergraduate-students-a-comparison-of-different-peer-teaching-approaches
#15
G Gradl-Dietsch, A K Menon, A Gürsel, A Götzenich, N Hatam, A Aljalloud, S Schrading, F Hölzl, M Knobe
BACKGROUND: The aim of this study was to assess the impact of different teaching interventions in a peer-teaching environment on basic echocardiography skills and to examine the influence of gender on learning outcomes. METHODS: We randomly assigned 79 s year medical students (55 women, 24 men) to one of four groups: peer teaching (PT), peer teaching using Peyton's four-step approach (PPT), team based learning (TBL) and video-based learning (VBL). All groups received theoretical and practical hands-on training according to the different approaches...
July 17, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28717767/breaking-bad-news-in-ethnic-settings-perspectives-of-patients-and-families-in-northern-sri-lanka
#16
Chrishanthi Rajasooriyar, Jenny Kelly, Thanikai Sivakumar, Gowcikan Navanesan, Shahini Nadarasa, Madona Hashanthy Sriskandarajah, Sabe Sabesan
PURPOSE: The discussion of a cancer diagnosis and prognosis often is difficult. This study explored the expectations of Tamil-speaking patients with cancer and their families with respect to receiving their cancer diagnosis in northern Sri Lanka. METHODS: This exploratory, descriptive, qualitative study used semistructured interviews. RESULTS: Thematic analysis identified two major themes: communication and information seeking. The findings illustrate a discrepancy between patient preference for direct disclosure of the diagnosis and that of families...
June 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/28717749/perceptions-and-barriers-of-survivorship-care-in-asia-perceptions-from-asian-breast-cancer-survivors
#17
Alexandre Chan, Zheng Kang Lum, Terence Ng, Tewodros Eyob, Xiao Jun Wang, Jung-Woo Chae, Sreemanee Dorajoo, Maung Shwe, Yan Xiang Gan, Rose Fok, Kiley Wei-Jen Loh, Yee Pin Tan, Gilbert Fan
PURPOSE: With the long-term goal to optimize post-treatment cancer care in Asia, we conducted a qualitative study to gather in-depth descriptions from multiethnic Asian breast cancer survivors on their perceptions and experiences of cancer survivorship and their perceived barriers to post-treatment follow-up. METHODS: Twenty-four breast cancer survivors in Singapore participated in six structured focus group discussions. The focus group discussions were voice recorded, transcribed verbatim, and analyzed by thematic analysis...
April 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/28717741/patient-reported-burden-of-a-neuroendocrine-tumor-net-diagnosis-results-from-the-first-global-survey-of-patients-with-nets
#18
Simron Singh, Dan Granberg, Edward Wolin, Richard Warner, Maia Sissons, Teodora Kolarova, Grace Goldstein, Marianne Pavel, Kjell Öberg, John Leyden
PURPOSE: Despite the considerable impact of neuroendocrine tumors (NETs) on patients' daily lives, the journey of the patient with a NET has rarely been documented, with published data to date being limited to small qualitative studies. NETs are heterogeneous malignancies with nonspecific symptomology, leading to extensive health care use and diagnostic delays that affect survival. A large, international patient survey was conducted to increase understanding of the experience of the patient with a NET and identify unmet needs, with the aim of improving disease awareness and care worldwide...
February 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/28717600/implementation-of-the-xpert-mtb-rif-assay-for-tuberculosis-in-mongolia-a-qualitative-exploration-of-barriers-and-enablers
#19
Nicole L Rendell, Solongo Bekhbat, Gantungalag Ganbaatar, Munkhjargal Dorjravdan, Madhukar Pai, Claudia C Dobler
OBJECTIVE: The aim of our study was to identify barriers and enablers to implementation of the Xpert MTB/RIF test within Mongolia's National Tuberculosis Program. METHODS: Twenty-foursemi-structured interviews were conducted between June and September 2015 with laboratory staff and tuberculosis physicians in Mongolia's capital Ulaanbaatar and regional towns where Xpert MTB/RIF testing had been implemented. Interviews were recorded, transcribed, translated and analysed thematically using NVIVO qualitative analysis software...
2017: PeerJ
https://www.readbyqxmd.com/read/28717515/changing-needs-for-information-and-support-in-an-online-system-for-parents-of-children-with-kidney-disease
#20
Maury Pinsk, David Nicholas
BACKGROUND: Pediatric chronic kidney disease is psychologically, financially, and physically demanding on parents providing care. Parents often feel isolated because of the rarity of the condition, and geographic isolation often compounds this perception in Canada. Many parents seek assistance online for both information and social support. OBJECTIVE: This study examines an online portal, titled "Ability Online," which was designed to provide support and information to a diverse group of parents using chat facilities, bulletin boards, and e-mail...
2017: Canadian Journal of Kidney Health and Disease
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