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https://www.readbyqxmd.com/read/29131489/evaluation-of-the-serum-zinc-level-in-adult-patients-with-melasma-is-there-a-relationship-with-serum-zinc-deficiency-and-melasma
#1
Majid Rostami Mogaddam, Nastaran Safavi Ardabili, Manouchehr Iranparvar Alamdari, Nasrollah Maleki, Maryam Aghabalaei Danesh
BACKGROUND: Melasma is a common acquired hypermelanosis of sun-exposed skin, particularly on the face, which presents as symmetric, light- to gray-brown-colored macules and patches. There are several studies of serum zinc levels in cutaneous disorders. So far, no studies have been carried out to assess the serum zinc level in patients with melasma. The aim of this study is to determine the serum zinc level in patients with melasma compared to healthy subjects. MATERIALS AND METHODS: A total of 118 patients with melasma and 118 healthy controls were enrolled in this prospective cross-sectional study...
November 12, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28926868/polycystic-ovary-syndrome-pcos-in-juvenile-and-adult-type-1-diabetes-in-a-german-austrian-cohort
#2
Christina Reinauer, Esther Bollow, Elke Fröhlich-Reiterer, Katharina Laubner, Dominik Bergis, Christof Schöfl, Hans-Peter Kempe, Michael Hummel, Pia Hennes, Katja Gollisch, Holger Haberland, Nicolin Datz, Thomas Meissner, Reinhard W Holl
Context While an association between PCOS and type 2 diabetes is well established, to date there have been few data on clinical care of type 1 diabetes (T1D) patients with PCOS. Objective The aim of our study was to characterize T1D patients with the comorbidity of PCOS within the DPV cohort with regard to diabetes phenotype, therapy and metabolic control. Design and Setting Clinical data from the prospective German/Austrian DPV cohort on patients with T1D and documented PCOS (n=76) were compared to female T1D controls (n=32,566) in reproductive age...
November 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/28713532/bilateral-cavernous-sinus-thrombosis-as-first-manifestation-of-primary-burkitt-lymphoma-of-the-thyroid-gland
#3
Mehdi Moghaddasi, Mona Nabovvati, Saeed Razmeh
Cavernous sinus thrombosis (CST) is a rare condition that is usually associated with infections, pregnancy, vasculitis and some types of medication, such as the contraceptive pill and paraneoplastic. Primary Burkitt lymphoma (PBL) of the thyroid gland is very uncommon and the clinical description of such cases has been largely limited to case reports. In this paper, we present a case of CST as the first manifestation of PBL of the thyroid gland. To the best of our knowledge, our patient is the first case report of PBL of the thyroid gland that presents with bilateral CST...
June 23, 2017: Neurology International
https://www.readbyqxmd.com/read/28588554/female-reproductive-factors-and-differentiated-thyroid-cancer
#4
REVIEW
Mariacarla Moleti, Giacomo Sturniolo, Maria Di Mauro, Marco Russo, Francesco Vermiglio
Differentiated thyroid cancer (DTC) is markedly more common in women than men, the highest female-to-male ratio being recorded during the reproductive period. This evidence has led to the suggestion that female hormonal and reproductive factors may account for the observed DTC gender disparity. This review focuses on current evidence on the risk of DTC in conjunction with major female reproductive factors, including the impact of pregnancy on DTC occurrence and progression/recurrence. Overall, studies exploring the link between the risk of DTC and menstrual and menopausal factors, oral contraceptives and/or hormone replacement therapy, showed these associations, if any, to be generally weak...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28525397/an-unusual-case-of-sudden-death-is-there-a-relationship-between-thyroid-disorders-and-fatal-pulmonary-thromboembolism-a-case-report-and-review-of-literature
#5
REVIEW
Isabella Aquila, Silvia Boca, Fiorella Caputo, Matteo A Sacco, Santo Gratteri, Vittorio Fineschi, Pietrantonio Ricci
In adults, the most common cause of sudden death is coronary heart disease or defects in the cardiac conduction system; however, there are many cases of sudden death occurring from other causes such as fatal pulmonary thromboembolism. Several risk factors are recognized, including hospitalization, surgery, obesity, pregnancy, the use of oral contraceptives, traumatic fractures, and genetic conditions, which cause hypercoagulable states such as factor V Leiden mutations. Although many risk factors have been identified, the mortality rate is still high...
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28511371/study-of-serum-total-psa-and-free-psa-as-an-oncological-marker-in-breast-tumour
#6
Elteza Tahjiba Jahir, Runi Devi, Bibhuti Bhushan Borthakur
INTRODUCTION: Breast Cancer (BC) cases are rising alarmingly all over the world and India is not an exception. This rising trend is due to an increased age at first child birth, decreased breast feeding, and the changing lifestyle mostly in urban India. With the advent of more sensitive methodologies and research works in this field, it has been suggested that Prostate Specific Antigen (PSA) plays an important role in the pathogenesis of breast cancer besides other established tumour markers...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28472893/prevalence-and-related-factors-of-irregular-menstrual-cycles-in-korean-women-the-5th-korean-national-health-and-nutrition-examination-survey-knhanes-v-2010-2012
#7
Eun-Kyung Jung, Seok-Won Kim, Sun-Myeong Ock, Kyu-In Jung, Chan-Hee Song
INTRODUCTION: There have been few population-based studies reporting medical, lifestyle and psychological factors associated with irregular menstrual cycles. This study aimed to elucidate the prevalence and related factors of irregular menstrual cycles in Korean women. METHODS: Cross-sectional data from the 5th Korean National Health and Nutrition Examination Survey were used. Eligible women were 19-40 years old, not currently taking oral contraceptives or using intrauterine devices, and not currently pregnant or breast feeding, and had no medical history of hysterectomy, thyroid diseases, cancers or renal failure...
May 4, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28431277/endocrine-disruption-by-environmental-gestagens-in-amphibians-a-short-review-supported-by-new-in%C3%A2-vitro-data-using-gonads-of-xenopus-laevis
#8
REVIEW
Andrea Ziková, Claudia Lorenz, Frauke Hoffmann, Wibke Kleiner, Ilka Lutz, Matthias Stöck, Werner Kloas
Endocrine disruption caused by various anthropogenic compounds is of persisting concern, especially for aquatic wildlife, because surface waters are the main sink of these so-called endocrine disruptors (ED). In the past, research focused on (anti)estrogenic, (anti)androgenic, and (anti)thyroidal substances, affecting primarily reproduction and development in vertebrates; however, other endocrine systems might be also targeted by ED. Environmental gestagens, including natural progestogens (e.g. progesterone (P4)) and synthetic progestins used for contraception, are supposed to affect vertebrate reproduction via progesterone receptors...
August 2017: Chemosphere
https://www.readbyqxmd.com/read/28426980/hormonal-and-reproductive-risk-factors-of-papillary-thyroid-cancer-a-population-based-case-control-study-in-france
#9
Emilie Cordina-Duverger, Christophe Leux, Monica Neri, Catherine Tcheandjieu, Anne-Valérie Guizard, Claire Schvartz, Thérèse Truong, Pascal Guénel
The three times higher incidence of thyroid cancer in women compared to men points to a role of female sex hormones in its etiology. However the effects of these factors are poorly understood. We analyzed the association between thyroid cancer and hormonal and reproductive factors among women enrolled in CATHY, a population-based case-control study conducted in France. The study included 430 cases of papillary thyroid cancer and 505 controls frequency-matched on age and area of residence. The odds ratios for thyroid cancer increased with age at menarche (p trend 0...
June 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28069897/impact-of-estrogen-receptor-%C3%AE-gene-and-oxytocin-receptor-gene-polymorphisms-on-female-sexuality
#10
Anastasia K Armeni, Konstantinos Assimakopoulos, Dimitra Marioli, Vassiliki Koika, Euthychia Michaelidou, Niki Mourtzi, Gregoris Iconomou, Neoklis A Georgopoulos
Over the past decades, research attention has increasingly been paid to the neurobiological component of sexual behavior. The aim of the present study was to investigate the correlation of estrogen receptor α (ERA) gene polymorphism (rs2234693-PvuII) (T→C substitution) and oxytocin receptor gene polymorphism (rs53576) (G→A substitution) with sexuality parameters of young, healthy women. One hundred thirty-three Greek heterosexual women, students in higher education institutions, 20-25 years of age, sexually active, with normal menstrual cycles (28-35 days), were recruited in the study...
January 2017: Endocrine Connections
https://www.readbyqxmd.com/read/27659896/pregnancy-and-the-hair-growth-cycle-anagen-induction-against-hair-growth-disruption-using-nourkrin-%C3%A2-with-marilex-%C3%A2-a-proteoglycan-replacement-therapy
#11
REVIEW
Erling Thom
Postpartum effluvium is a well-known clinical fact. However, following some minor research activities in the 1960s, very little has happened on the research front of the subject. It was hypothesized that postpartum hair loss might be a manifestation of a change in the hair growth cycle occurring normally during pregnancy. Recently, new research has been published trying to explain the mechanism of action behind this frequently occurring hair growth disruption, and to develop a functional treatment schedule and regime...
September 23, 2016: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/27599836/successful-live-birth-in-a-woman-with-resistant-ovary-syndrome-following-in-vitro-maturation-of-oocytes
#12
Yu Li, Ping Pan, Ping Yuan, Qi Qiu, Dongzi Yang
BACKGROUND: Resistant ovary syndrome (ROS) is a rare endocrine disorder characterized with hypergonadotrophic hypogonadism. Infertility is a common complaint of woman presenting with ROS, and little progress has been made in term of reproduction with the patient's own gamete. So far only one case report of live birth has been reported after in vitro maturation (IVM) of oocytes in a patient suffering from ROS in 2013. CASE PRESENTATION: A secondary infertile woman of 33 years-old was manifested with oligomenorrhea and markedly increased gonadotropin levels around postmenopausal range, but had normal antral follicle count, normal serum inhibin B and anti-Müllerian hormone levels...
September 6, 2016: Journal of Ovarian Research
https://www.readbyqxmd.com/read/27334113/drug-prescribing-trends-in-adults-with-rheumatoid-arthritis-a-population-based-comparative-study-from-2005-to-2014
#13
Jorge A Zamora-Legoff, Elena Myasoedova, Eric L Matteson, Sara J Achenbach, Cynthia S Crowson
The aim of this study was to examine drug prescribing trends for patients with rheumatoid arthritis (RA) over recent years and compare them to matched non-RA subjects. Retrospective prescription data were examined from 2005 to 2014 in a population-based incidence cohort of patients with RA and comparable non-RA subjects. Drugs for or related to the treatment of RA were excluded. Comparisons between cohorts of percentages of patients with at least one prescription in a specific drug category/class were performed using Poisson regression models adjusted for age and sex...
October 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27216973/epidemiology-of-endometriosis-and-its-comorbidities
#14
F Parazzini, G Esposito, L Tozzi, S Noli, S Bianchi
Genetic profile, inflammation, hormonal activity, menstrual cyclicity, organochlorine burden, prostaglandin metabolism and immunological factors have been suggested to play a role in the establishment and development of endometriosis. From the epidemiological perspective, several risk factors have been studied to suggest or support the different aetiological hypotheses. Social class and family history apart, the factors most consistently associated with endometriosis are early age at menarche and long and heavy menstrual cycles...
February 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27114331/novel-correlates-between-antim%C3%A3-llerian-hormone-and-menstrual%C3%A2-cycle-characteristics-in%C3%A2-african-american-women-23-35%C3%A2-years-old
#15
Erica E Marsh, Lia A Bernardi, Marissa L Steinberg, Peter J de Chavez, Jenny A Visser, Mercedes R Carnethon, Donna D Baird
OBJECTIVE: To characterize normative antimüllerian hormone (AMH) levels and ascertain which factors are associated with AMH in a large cohort of reproductive-age women. DESIGN: Cross-sectional study. SETTING: Not applicable. PATIENT(S): A total of 1,654 African-American women (AAW) ages 23-34 at recruitment. INTERVENTION(S): Not applicable. MAIN OUTCOME MEASURE(S): Serum AMH measured using an ultrasensitive ELISA...
August 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27099539/adverse-obstetrical-and-perinatal-outcome-in-adolescent-mothers-associated-with-first-birth-a-hospital-based-case-control-study-in-a-tertiary-care-hospital-in-north-east-india
#16
Robin Medhi, Banani Das, Arpana Das, Mansur Ahmed, Sonika Bawri, Suditi Rai
PURPOSE: To analyze the adverse obstetrical and perinatal outcome of adolescent mothers associated with first birth. PATIENTS AND METHODS: This prospective case-control study was conducted in a tertiary care teaching hospital of North-East India between January 2014 and December 2014. All adolescent primigravidae completing 28 weeks of gestation with singleton pregnancy and delivered at our institution were included in the study group. Primigravidae aged between 20 and 25 years were taken as a control group...
2016: Adolescent Health, Medicine and Therapeutics
https://www.readbyqxmd.com/read/26999878/prevention-and-management-of-pregnancy-in-adolescents-with-endocrine-disorders
#17
REVIEW
Paula J Adams Hillard
Because 83% of adolescent pregnancies among teens 15 to 19 years old are unintended and because adolescents with chronic medical conditions are as likely to be sexually involved as are healthy teens, preventing unintended pregnancies among teens with chronic endocrine conditions, including diabetes mellitus (both types 1 and 2), PCOS, and thyroid dysfunction, is critically important. Evidence-based guidelines are available to assist with assessment of the risks versus the benefits of specific options for contraception in teens with these and other medical conditions...
August 2015: Adolescent Medicine: State of the Art Reviews
https://www.readbyqxmd.com/read/26987767/frontal-fibrosing-alopecia-possible-association-with-leave-on-facial-skin-care-products-and-sunscreens-a-questionnaire-study
#18
MULTICENTER STUDY
N Aldoori, K Dobson, C R Holden, A J McDonagh, M Harries, A G Messenger
BACKGROUND: Since its first description in 1994, frontal fibrosing alopecia (FFA) has become increasingly common, suggesting that environmental factors are involved in the aetiology. OBJECTIVES: To identify possible causative environmental factors in FFA. METHODS: A questionnaire enquiring about exposure to a wide range of lifestyle, social and medical factors was completed by 105 women with FFA and 100 age- and sex-matched control subjects...
October 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/26942253/cabozantinib-cometriq%C3%A2-in-medullary-thyroid-cancer-more-harmful-than-beneficial-as-is-vandetanib
#19
COMPARATIVE STUDY
(no author information available yet)
Surgery is the mainstay of treatment for medullary thyroid cancer. Cytotoxic chemotherapy is generally ineffective in patients with progressive, inoperable, advanced-stage or metastatic tumours. Vandetanib is also authorised in this setting, but it has more harms than benefits. Cabozantinib, like vandetanib, inhibits several tyrosine kinases involved in angiogenesis. Cabozantinib has been authorised in the European Union for use in this setting. In a randomised, placebo-controlled trial in 330 patients, adding cabozantinib to tailored symptomatic treatment did not prolong survival or improve symptoms, despite a favourable effect on tumour imaging and certain laboratory parameters...
January 2016: Prescrire International
https://www.readbyqxmd.com/read/26769886/diagnosis-and-management-of-breast-milk-oversupply
#20
REVIEW
Lauren Trimeloni, Jeanne Spencer
Managing breastfeeding problems is an essential part of newborn care. While much is written on breast milk undersupply, little is written on oversupply, sometimes known as hyperlactation or hypergalactia. Infants of mothers with oversupply may have increased or decreased weight gain. Some may have large, frothy stools. They may develop a disordered latch. Mothers may report overly full, leaking breasts. Thyroid function should be assessed. Treatment is mostly anecdotal and includes methods to maintain breast fullness, such as block feedings...
January 2016: Journal of the American Board of Family Medicine: JABFM
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