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https://www.readbyqxmd.com/read/29454166/a-water-based-topical-chinese-traditional-medicine-zicao-for-wound-healing-developed-using-2-hydroxypropyl-%C3%AE-cyclodextrin
#1
Ta Chen Chen, Song-Cu Yu, Chin-Mu Hsu, Fuu-Jen Tsai, Yuhsin Tsai
Zicao is a traditional Chinese herbal medicine that has been used for the topical treatment of wounds in the form of oil-based ointment for several hundred years. To overcome the disadvantages of oil-based ointment such as irritation, discomfort, and difficulty in cleaning, this study developed a water-based topical formulation of Zicao. An ethanol extract of Zicao was included in 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) to form a water-soluble Zicao-HP-β-CD complex. The formation of the Zicao-HP-β-CD complex was determined using LC-MS, 1 H NMR, ROSEY, and solubility analysis...
February 10, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29453270/retraction-effect-of-acupuncture-and-chinese-herbal-medicine-on-subacute-stroke-outcomes-a-single-center-randomized-controlled-trial
#2
(no author information available yet)
No abstract text is available yet for this article.
February 16, 2018: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
https://www.readbyqxmd.com/read/29452699/hypolipidemic-components-from-medicine-food-homology-species-used-in-china-pharmacological-and-health-effects
#3
REVIEW
De-Xing Song, Jian-Guo Jiang
Hyperlipidemia is a systemic disease caused by abnormal human lipid metabolism. Dietary control and treatment on hyperlipidemia is now a popular therapy pathway. This paper focuses on the medicine food homology (MFH) species used in China with hypolipidemic function, and emphasizes on the active ingredients and their pharmacological effect. The single herbal and its hypolipidemic active ingredients are summarized through reviewing the relevant literatures published in the past twenty years. The ingredients are divided into polysaccharides, flavonoids, steroidal saponins, quinones, alkaloids and others, of which the related researches are described from the aspects of sources, model and method, result and mechanisms, respectively...
February 13, 2018: Archives of Medical Research
https://www.readbyqxmd.com/read/29449878/complete-chloroplast-genome-of-the-medicinal-plant-amomum-compactum-gene-organization-comparative-analysis-and-phylogenetic-relationships-within-zingiberales
#4
Ming-Li Wu, Qing Li, Jiang Xu, Xi-Wen Li
Background: Amomum compactum is one of the basic species of the traditional herbal medicine amomi fructus rotundus, with great pharmacology effect. The system position of A. compactum is not clear yet, and the introduction of this plant has been hindered by many plant diseases. However, the correlational molecular studies are relatively scarce. Methods: The total chloroplast (cp) DNA was extracted according to previous studies, and then sequenced by 454 GS FLX Titanium platform...
2018: Chinese Medicine
https://www.readbyqxmd.com/read/29449876/authenticity-analyses-of-rhizoma-paridis-using-barcoding-coupled-with-high-resolution-melting-bar-hrm-analysis-to-control-its-quality-for-medicinal-plant-product
#5
Bao-Zhong Duan, Ya-Ping Wang, Hai-Lan Fang, Chao Xiong, Xi-Wen Li, Ping Wang, Shi-Lin Chen
Background: Rhizoma Paridis (Chonglou) is a commonly used and precious traditional Chinese medicine. Paris polyphylla Smith var. yunnanensis (Franch.) Hand. -Mazz. and Paris polyphylla Smith var . chinensis (Franch.) Hara are the two main sources of Chonglou under the monograph of Rhizoma Paridis in Chinese Pharmacopoeia. In the local marketplace, however, this medicine is prone to be accidentally contaminated, deliberately substituted or admixed with other species that are similar to Rhizoma Paridis in shape and color...
2018: Chinese Medicine
https://www.readbyqxmd.com/read/29449812/calycosin-orchestrates-osteogenesis-of-danggui-buxue-tang-in-cultured-osteoblasts-evaluating-the-mechanism-of-action-by-omics-and-chemical-knock-out-methodologies
#6
Amy G W Gong, Ran Duan, Huai Y Wang, Tina T X Dong, Karl W K Tsim
Danggui Buxue Tang (DBT), an ancient Chinese herbal decoction commonly used to mitigate menopausal osteoporosis, contains two herbs: Astragali Radix (AR) and Angelicae Sinensis Radix (ASR). The exact efficacy of individual chemical(s) within DBT, or in any herbal mixture, is hard to be revealed. Calycosin and ferulic acid have been reported to be the predominant chemicals found within DBT, and its roles in regulating osteoblastic differentiation have been proposed here. To probe the roles of calycosin and ferulic acid, these chemicals were specifically depleted from the DBT extracts...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29448088/antioxidant-activity-and-total-phenolic-content-of-ethanolic-extract-of-pomegranate-peels-juice-and-seeds
#7
Zahra Derakhshan, Margherita Ferrante, Marzieh Tadi, Farnoosh Ansari, Ali Heydari, Motahreh Sadat Hosseini, Gea Oliveri Conti, Elham Khalili Sadarabad
Pomegranate (Punica granatum L.) is extensively cultivated in Middle East especially in Iran. For centuries, this fruit has been used in Iranian herbal medicine. Pomegranate peel, seed and juice contain considerable amounts of phenolic compounds and have antioxidant activity. Pomegranate peels, juice and seeds from three regions of Natanz, Shahreza, and Doorak were obtained. Antioxidant activity, total phenolic, flavonoids, and flavonols contents of pomegranate peels, seeds and juices extracts were analyzed...
February 12, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29447984/salicin-7-sulfate-a-new-salicinoid-from-willow-and-implications-for-herbal-medicine
#8
Clarice Noleto-Dias, Jane L Ward, Alice Bellisai, Charlotte Lomax, Michael H Beale
Willow (Salix sp.) is a historically well-known herbal medicine that provided the lead compound (salicin) for the discovery of aspirin, one of the most successful plant derived drugs in human medicine. During a metabolomics screen of 86 Salix species contained in the UK National Willow Collection, we have discovered, isolated and fully characterised a new natural salicinoid - salicin-7-sulfate. This molecule may have important human pharmacological actions that need to be considered in determining the efficacy and safety of willow herbal medicines...
February 12, 2018: Fitoterapia
https://www.readbyqxmd.com/read/29446788/the-potential-role-of-herbal-products-in-the-treatment-of-parkinson-s-disease
#9
M S Amro, S L Teoh, A G Norzana, D Srijit
Parkinson's disease (PD) is a multifactorial disorder of the nervous system in which there is a progressive loss of dopaminergic neurons. There is a disturbance in the movement in PD and these include resting tremors, rigidity, bradykinesia or akinesia, disturbance, posture and freezing (motor block). The substantia nigra and other parts of the brain are commonly affected. The disorder could be related to oxidative stress and there is an important role of reactive oxygen species (ROS). A number of herbal products contain active components which are known to possess antioxidant action...
January 2018: La Clinica Terapeutica
https://www.readbyqxmd.com/read/29446722/herbal-compounds-with-special-reference-to-gastrodin-as-potential-therapeutic-agents-for-microglia-mediated-neuroin%C3%AF-ammation
#10
Juan-Juan Li, Shun-Jin Liu, Xiao-Yu Liu, Eng-Ang Ling
BACKGROUND: Activated microglia play a pivotal role neurodegenerative diseases by producing a variety of proinflammatory mediators including tumor necrosis factor-alpha (TNF-α), interleukin-1bea (IL-1β) and nitric oxide (NO) that are toxic to neurons and oligodendrocytes. METHODS: In view of the above, suppression of microglia mediated neuroinflammation is deemed a therapeutic strategy for neurodegenerative diseases. Several potential Chinese herbal extracts have been reported to exert neuroprotective effects against neurodegenerative diseases targeting specifically at the activated microglia...
February 14, 2018: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29445628/medicinal-properties-of-adiantum-capillus-veneris-linn-in-traditional-medicine-and-modern-phytotherapy-a-review-article
#11
REVIEW
Sahar Dehdari, Homa Hajimehdipoor
Background: Adiantum capillus-veneris Linn (Maidenhair fern) is an herb belonging to the family Pteridaceae. It is named as " Pare-siavashan " in medical and pharmaceutical textbooks of Iranian Traditional Medicine. The fronds of Maidenhair fern were mainly administrated by ancient physicians as single medicine or in combination with other plants in multi-herbal formulations for curing different diseases. Because of different chemical compositions, the herb fronds were also assessed for its numerous pharmacological effects...
February 2018: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29445390/approaches-and-recent-developments-for-the-commercial-production-of-semi-synthetic-artemisinin
#12
REVIEW
Stephanie H Kung, Sean Lund, Abhishek Murarka, Derek McPhee, Chris J Paddon
The antimalarial drug artemisinin is a natural product produced by the plant Artemisia annua . Extracts of A. annua have been used in Chinese herbal medicine for over two millennia. Following the re-discovery of A. annua extract as an effective antimalarial, and the isolation and structural elucidation of artemisinin as the active agent, it was recommended as the first-line treatment for uncomplicated malaria in combination with another effective antimalarial drug (Artemisinin Combination Therapy) by the World Health Organization (WHO) in 2002...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29445375/the-role-of-cytochromes-p450-in-infection
#13
REVIEW
Elisavet Stavropoulou, Gratiela G Pircalabioru, Eugenia Bezirtzoglou
Cytochromes are expressed in many different tissues of the human body. They are found mostly in intestinal and hepatic tissues. Cytochromes P450 (CYPs) are enzymes that oxidize substances using iron and are able to metabolize a large variety of xenobiotic substances. CYP enzymes are linked to a wide array of reactions including and O-dealkylation, S-oxidation, epoxidation, and hydroxylation. The activity of the typical P450 cytochrome is influenced by a variety of factors, such as genus, environment, disease state, herbicide, alcohol, and herbal medications...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29444684/medicinal-plants-used-by-traditional-healers-to-treat-malignancies-and-other-human-ailments-in-dalle-district-sidama-zone-ethiopia
#14
Nigatu Tuasha, Beyene Petros, Zemede Asfaw
BACKGROUND: Medicinal plants (MPs) used by traditional healers (THs) were investigated in Megera and adjacent subdistricts (kebeles) of Dalle District, Sidama Zone, southern Ethiopia. The objective of the study was to identify and record MPs and their traditional uses in the treatment of various human ailments with emphasis on malignancies and other most frequently reported diseases. METHODS: Traditional medicinal knowledge held by 20 THs was investigated following standard ethnobotanical approaches...
February 14, 2018: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/29444611/the-effect-of-goreisan-on-the-prevention-of-chronic-subdural-hematoma-recurrence-multicenter-randomized-controlled-study
#15
Kosuke Katayama, Naoya Matsuda, Kiyohide Kakuta, Masato Naraoka, Atsuhito Takemura, Seiko Hasegawa, Kenichi Akasaka, Norihito Shimamura, Katsuhiro Itoh, Kenichiro Asano, Konno Hiromu, Hiroki Ohkuma
The relatively high rate of postoperative recurrence in the treatment of chronic subdural hematoma (CSDH) is a significant problem. Goreisan is an herbal medicine that exhibits a hydragogue effect by inhibiting the expression of aquaporins, and its efficacy in preventing postoperative CSDH recurrence has been suggested by several case trials. This multicenter, prospective, randomized controlled trial was performed to investigate the preventative effect of goreisan on postoperative CSDH recurrence. Patients with symptomatic CSDH over 60 years old undergoing burr hole surgery were enrolled in this study...
February 14, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29442084/comparative-evaluation-of-antiplaque-and-antigingivitis-effects-of-an-herbal-and-chlorine-dioxide-mouthwashes-a-clinicomicrobiological-study
#16
Srinivasa T Siddeshappa, Shruti Bhatnagar, Ramreddy K Yeltiwar, Humera Parvez, Asmita Singh, Saket Banchhor
Aim: The aim of the present study was to compare the efficacy of herbal mouthwash and chlorine dioxide mouthwash in reduction of plaque and gingivitis. Settings and Design: In a randomized clinical trial, forty patients were randomly selected and divided equally into two groups. Materials and Methods: After professional oral prophylaxis, the clinical parameters plaque index, gingival index, and modified sulcular bleeding index were recorded at baseline, 7 th day, 14 th day, and 21 st day...
January 2018: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/29442017/determination-of-coumarin-in-seasonal-bakery-products-using-quechers-and-gc-ms
#17
F Vetter, C Müller, M Stöckelhuber, F Bracher
Cinnamon is a traditional herbal drug, but more importantly, it is used as a flavor compound in the production of foodstuff. Due to the content of significant concentrations of coumarin in Cassia cinnamon, effective control of the coumarin content in seasonal bakery products like ginger bread and cinnamon biscuits is urgently needed. Here we present a novel, fast and fully validated protocol for the determination of coumarin in marketed bakery products using the QuEChERS sample preparation technique in combination with GC-MS analysis...
June 1, 2017: Die Pharmazie
https://www.readbyqxmd.com/read/29441985/total-phenolic-and-tannins-determination-a-modification-of-ph-eur-2-8-14-for-higher-throughput
#18
S Wiesneth, G Jürgenliemk
A principle mostly being used to quantify phenols and tannins is the Folin-Ciocalteu's reagent method described in the European Pharmacopeia's method 2.8.14. Aim of the present study was to simplify this procedure in order to handle larger sample numbers. By changing the wavelength, the amounts of reagents, miniaturizing the setting to microtiter scale and changing the incubation time before measurement, the Ph. Eur. method 2.8.14 was optimized for a larger number of experiments. Calibration curves and time kinetics with different phenolic compounds (catechol, procyanidin B1, gallic acid, (+)-catechin, tannic acid, salicylic acid, ferulic acid) were determined...
April 1, 2017: Die Pharmazie
https://www.readbyqxmd.com/read/29439653/unexplained-chronic-liver-disease-in-ethiopia-a-cross-sectional-study
#19
Stian Magnus Staurung Orlien, Nejib Yusuf Ismael, Tekabe Abdosh Ahmed, Nega Berhe, Trine Lauritzen, Borghild Roald, Robert David Goldin, Kathrine Stene-Johansen, Anne Margarita Dyrhol-Riise, Svein Gunnar Gundersen, Marsha Yvonne Morgan, Asgeir Johannessen
BACKGROUND: Hepatitis B virus (HBV) infection is assumed to be the major cause of chronic liver disease (CLD) in sub-Saharan Africa. The contribution of other aetiological causes of CLD is less well documented and hence opportunities to modulate other potential risk factors are being lost. The aims of this study were to explore the aetiological spectrum of CLD in eastern Ethiopia and to identify plausible underlying risk factors for its development. METHODS: A cross-sectional study was undertaken between April 2015 and April 2016 in two public hospitals in Harar, eastern Ethiopia...
February 13, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29439451/wogonin-suppresses-the-activity-of-matrix-metalloproteinase-9-and-inhibits-migration-and-invasion-in-human-hepatocellular-carcinoma
#20
Ming Hong, Honghui Cheng, Lei Song, Wencai Wang, Qi Wang, Donggang Xu, Weiwei Xing
As one of the major active ingredients in Radix Scutellariae, wogonin has been shown to be associated with various pharmacological activities on cancer cell growth, apoptosis, and cell invasion and migration. Here, we demonstrated that wogonin may harbor potential anti-metastatic activities in hepatocarcinoma (HCC). The anti-metastasis potential of wogonin and its underlying mechanisms were evaluated by ligand-protein docking approach, surface plasmon resonance assay, and in vitro gelatin zymography studies...
February 11, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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