Camila Maringolo Ribeiro, Cesar Augusto Roque-Borda, Maria Carolina Franzini, Karyn Fernanda Manieri, Fernanda Manaia Demarqui, Débora Leite Campo, Rachel Temperani Amaral Machado, Isabel Cristiane da Silva, Marcela Tavares Luiz, Leonardo Delello Di Filippo, Patrícia Bento da Silva, Márcia Cristina Oliveira da Rocha, Sônia Nair Báo, Domiziana Masci, Guilherme F S Fernandes, Daniele Castagnolo, Marlus Chorilli, Fernando Rogério Pavan
Tuberculosis (TB) is an infectious disease that annually affects millions of people, and resistance to available antibiotics has exacerbated this situation. Another notable characteristic of Mycobacterium tuberculosis, the primary causative agent of TB, is its ability to survive inside macrophages, a key component of the immune system. In our quest for an effective and safe treatment that facilitates the targeted delivery of antibiotics to the site of infection, we have proposed a nanotechnology approach based on an iron chelator...
March 25, 2024: International Journal of Pharmaceutics