Kyan Younes, Valentina Borghesani, Maxime Montembeault, Salvatore Spina, Maria Luisa Mandelli, Ariane E Welch, Elizabeth Weis, Patrick Callahan, Fanny M Elahi, Alice Y Hua, David C Perry, Anna Karydas, Daniel Geschwind, Eric Huang, Lea T Grinberg, Joel H Kramer, Adam L Boxer, Gil D Rabinovici, Howard J Rosen, William W Seeley, Zachary A Miller, Bruce L Miller, Virginia E Sturm, Katherine P Rankin, Maria Luisa Gorno-Tempini
Focal anterior temporal lobe degeneration often preferentially affects the left or right hemisphere. While patients with left-predominant anterior temporal lobe atrophy show severe anomia and verbal semantic deficits and meet criteria for semantic variant primary progressive aphasia and semantic dementia, patients with early right anterior temporal lobe atrophy are more difficult to diagnose as their symptoms are less well understood. Focal right anterior temporal lobe atrophy is associated with prominent emotional and behavioural changes, and patients often meet, or go on to meet, criteria for behavioural variant frontotemporal dementia...
November 21, 2022: Brain