Read by QxMD icon Read

sinonasal tumor

Moujahed Labidi, Kentaro Watanabe, Shunya Hanakita, Hun Ho Park, Schahrazed Bouazza, Anne-Laure Bernat, Sébastien Froelich
INTRODUCTION: Variations and additions to the endoscopic endonasal exposure have been proposed around a "modular" strategy. These extensions are often necessary to provide additional working space and reduce conflict between the instruments and the endoscope. Resection of endonasal structures, which affects negatively the sinonasal quality of life (QOL), is thus undertaken not only to obtain tumor exposure but also to improve the maneuverability of the instruments. METHODS: Our objective was to achieve the same skull base exposures and tumor resections while limiting the surgical footprint on sinonasal structures and patients' QOL...
June 7, 2018: World Neurosurgery
Kerem Ozturk, Rakhee Gawande, Mehmet Gencturk, Kevin Boegel, Emiro Caicedo-Granados, Zuzan Cayci
INTRODUCTION: Sinonasal inflammatory conditions account for a major component of head and neck pathologies, whereas neoplasms involving the sinonasal region make up only 2-3% of all head and neck lesions. The symptoms of sinonasal tumors are nonspecific; imaging plays a critical role in distinguishing benign and malignant disease and may illustrate characteristic radiological features of specific sinonasal tumors. OBJECTIVE: Aim was to determine the utilization of multimodality imaging, specifically the metabolic information provided by 18-fluorodeoxyglucose positron emission tomography (18 F-FDG PET/CT) and diffusivity characteristics seen with diffusion weighted images (DWI) of magnetic resonance imaging (MRI), in a wide range of benign and malignant sinonasal tumors drawn from over 200 sinonasal lesions from our institution and supplemented by the literature...
May 30, 2018: Clinical Imaging
Lichuan Zhang, Chunhua Hu, Xiaodan Zheng, Dawei Wu, Haili Sun, Wei Yu, Ying Wu, Dong Chen, Qianwen Lv, Ping Zhang, Xiping Li, Honggang Liu, Yongxiang Wei
RATIONALE: Oncocytic Schneiderian papillomas (OSP) are an uncommon type of sinonasal papillomas that arise from the Schneiderian epithelium, accounting for only 6% of all sinonasal papillomas. Malignancies arising in OSP are rare and are almost always described as in situ or invasive squamous cell carcinoma, although mucoepidermoid, small cell carcinoma and sinonasal undifferentiated carcinoma have also been reported. To our knowledge, only 18 such instances have been reported in the medical literature...
June 2018: Medicine (Baltimore)
Chan-Jung Chang, Chuan-Hung Sun, Tzu-Sheng Chen, Hung-Pin Wu
A glomangiopericytoma, or sinonasal type hemangiopericytoma, is a rare lesion which accounts for <0.5% of all sinonasal tumors. The mainstay treatment is wide excision. Instead of traditional open surgical approaches, such as midfacial degloving or lateral rhinotomy, we offer a case of 21-year-old male with diagnosis of glomangiopericytoma with skull base and intraorbital invasion and received navigation-assisted endoscopic excision of a glomangiopericytoma.
April 2018: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
J W Sun, Y F Wang, T Guo, Z Y Bie, W Gao, F Yin
No abstract text is available yet for this article.
May 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Vickie Y Jo, Adrián Mariño-Enríquez, Christopher D M Fletcher, Jason L Hornick
Biphenotypic sinonasal sarcoma (BSNS) is a distinctive, anatomically restricted, low-grade spindle cell sarcoma that shows considerable histologic overlap with other cellular spindle cell neoplasms. This tumor type shows both myogenic and neural differentiation, which can be demonstrated by immunohistochemistry; however, the available diagnostic markers are relatively nonspecific. BSNS is characterized by PAX3 rearrangements, with MAML3 as the most common fusion partner. Our aim was to determine whether immunohistochemistry using a monoclonal PAX3 antibody could distinguish BSNS from potential histologic mimics, as well as to evaluate a widely available polyclonal PAX8 antibody, which is known to cross-react with other paired box transcription factor family members...
May 31, 2018: American Journal of Surgical Pathology
Benjamin G Barrena, Billy J Phillips, Kenneth J Moran, Sasha J Betz
Ameloblastomas are benign but aggressive odontogenic tumors that most commonly affect the posterior mandible. Approximately 15% occur in the maxilla, with a subset thought to originate from the epithelial lining of the sinonasal cavities. Histologically, sinonasal ameloblastomas are identical to those of the oral cavity, with classical features of palisaded columnar basilar cells surrounding a central proliferation that resembles the stellate reticulum of a developing tooth. Unlike the gnathic variant, sinonasal ameloblastomas tend to affect males more than females, and the incidence of diagnosis peaks at a later age, approximately 60 years old...
May 30, 2018: Head and Neck Pathology
Christoph Becker, Kilian Konrad Kenjiro Dahlem, Kitty Lange, Manuel Christoph Ketterer, Jens Pfeiffer
INTRODUCTION: To evaluate the influence of comorbidities and anemia on outcome and survival in patients with sinonasal carcinomas. MATERIALS AND METHODS: Review of medical records of 121 patients with carcinoma treated at a single quaternary medical care and cancer center between 2002 and 2015. Comorbidities were classified according to the age-adjusted Charlson comorbidity index (ACCI) scoring system. RESULTS: 71 patients were male, 50 were female...
May 9, 2018: Journal of Cranio-maxillo-facial Surgery
Piotr Czapiewski, Michał Kunc, Adam Gorczyński, Johannes Haybaeck, Krzysztof Okoń, Joanna Reszec, Anna Lewczuk, Jaroslaw Dzierzanowski, Joanna Karczewska, Wojciech Biernat, Mario Turri-Zanoni, Paolo Castelnuovo, Cecilia Taverna, Alessandro Franchi, Stefano La Rosa, Fausto Sessa, Günter Klöppel
Olfactory neuroblastoma (ONB) is a malignant neuroendocrine neoplasm with a usually slow course, but with considerable recurrence rate. Many neuroendocrine tumors have shown good response to the treatment with somatostatin analogues and somatostatin radioreceptor therapy. In ONBs, there are scarce data on somatostatin-based treatment and the cellular expression of somatostatin receptors (SSTR), the prerequisite for binding and effect of somatostatin on normal and tumor cells. The aim of our study was to investigate the immunohistochemical expression of somatostatin receptor (SSTR) 2A and 5 in a cohort of 40 ONBs...
May 25, 2018: Human Pathology
Hong Li, Sina J Torabi, Wendell G Yarbrough, Saral Mehra, Heather A Osborn, Benjamin Judson
Importance: Data are limited on the prognostic value of human papillomavirus (HPV) status for head and neck carcinoma subsites. Objective: To determine whether HPV positivity at each head and neck subsite is associated with improved overall survival. Design, Setting, and Participants: This retrospective population-based cohort study used the National Cancer Database to identify patients diagnosed with head and neck squamous cell carcinomas from January 1, 2010, to December 31, 2014...
May 10, 2018: JAMA Otolaryngology—Head & Neck Surgery
M H Wang, B Guan, A M Yu, B Y Dai, Q Yan, S S Chen
Objective: To evaluate the influence risk factors of recurrence and the methods for reducing recurrence of sinonasal inverted papilloma (SNIP). Method: Clinical data of 34 patients with SNIP were analyzed retrospectively. All of them were unilateral onset. The diagnosis was confirmed pathologically and the range of lesions was determined by endoscopic and imaging examination; clinical classification according to Krouse classification method; All operations were performed under nasal endoscope, of which 20 cases were operated by simple nasal endoscope, and 14 cases were operated by endoscopic anterior lacrimal recess approach...
December 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
J S Wang, A H Yan
Objective: The aim of this study is to evaluate the relationship between the expression of P16 and infection of HPV16 in sinonasal squamous cell carcinoma and its clinical and pathological features, futher prognosis was also investigated. Method: Fifty-five cases of sinonasal squamous cell carcinoma were collected,twenty cases of nasal in-verted papilloma and twenty cases of nasal polyp were chose as control. The expression of P16 and infection of HPV16 were detected by immunohistochemistry in both experimental group and control group...
December 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Y H Zhang, Q C Duan, Q Zuo, C Du, L F Xie, L Zhu
Objective: To investigate the clinical manifestation, imaging and histological features of different histological subtypes of non-Hodgkin's lymphoma of nasal cavity and paranasal sinuses. Method: Fifteen NHL patients of the sinonasal region were collected from the Department of Otolaryngology of Peking University Third Hospital from 2010 to 2016. HE staining and immunohistochemical staining were performed. The clinical characteristics and imaging features of different subtypes were described and analyzed. Result: :We analyzed a total of 6 patients with localized sinonasal diffuse large B cell lymphoma and 9 patients with localized sinonasal extranodal NK/T cell lymphoma...
November 5, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
S M Ju, F Chen, J Liu, G Qin, Y L Xie, Z L Wang, X M Wei
Objective: To establish a stable and reliable orthotopic murine model of mucosal malignant melanoma of the maxillary sinus so as to provide animal models for further studying for pathogenesis and therapy of sinonasal malignancy. Method: B16 were implanted in the right maxillary sinus of male nude mice. After tumors appeared in right maxillary sinus, tumor growth and survival rate were recorded. The degree of tumor infiltration was observed through the MRI. Result: Mice with B16 implanted in right maxillary sinus developed primary tumors...
October 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
J L Liu, L Y Zhang, D F Yao, J E Li
Objective: To study the clinical features and nasal image of children with nasal tumors. Method: The samples of 40 cases of pediatric nasal tumors, which were diagnosed based on pathology, were collected. Clinical features, pathological histology and imaging characteristics were also summarized. Result: There were 23 cases of benign tumors and 17 cases of malignancy. The most common benign tumors were angiofibroma (7 cases), capillary hemangioma (4 cases) and ossifying fibroma (4 cases), while the most common malignant tumors were lymphoma (10 cases) and embryonal rhabdomyosarcoma (3 cases)...
October 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
D N Kapitanov, L A Satanin, N A Chernikova, L V Shishkina, E V Shelesko, S R Arustamyan, E Yu Bukharin
Schwannomas (neurinomas) are benign, encapsulated, and slow-growing neoplasms developing from any peripheral, cranial, or vegetative nerve that has the Schwann sheath. Schwannomas of the nasal cavity and paranasal sinuses in adults occur rarely, less than 4% of cases. The world literature lacks similar data for the pediatric age group because these tumors in children are unique and extremely rare. The most common clinical symptoms of sinonasal schwannoma are nasal breathing disorders, hyposmia or anosmia, and snoring at night...
2018: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
Goh Eui-Kyung, Cho Ilyoung, Oh Se-Joon, Choi Sung-Won, Kim Young-Keum
An inverted papilloma is a benign neoplasm that occurs exclusively in the sinonasal cavity; an inverted papilloma involving the mastoid cavity is extremely rare. We present the case of a patient with an inverted papilloma of the mastoid cavity secondary to cholesteatoma surgery. No case that occurred after acquired cholesteatoma has been reported in literature. A 39-year-old female who was diagnosed with cholesteatoma was treated with a modified radical mastoidectomy in 1988. After recurrence, the patient underwent a canal wall down mastoidectomy in 2006...
April 2018: Journal of International Advanced Otology
Marco A Mascarella, Abdulaziz Alrasheed, Naif Fnais, Ophelie Gourgas, Ghulam Jalani, Marta Cerruti, Marc A Tewfik
Inverted papillomas are tumors of the sinonasal tract with a propensity to recur. Raman spectroscopy can potentially identify inverted papillomas from other tissue based on biochemical signatures. A pilot study comparing Raman spectroscopy to histopathology for 3 types of sinonasal tissue was performed. Spectral data of biopsies from patients with normal sinonasal mucosa, chronic rhinosinusitis, and inverted papillomas are compared to histopathology using principal component analysis and linear discriminant analysis after data preprocessing...
May 1, 2018: Otolaryngology—Head and Neck Surgery
Santosh Tummidi, Kanchan Kothari, Roshni Patil, Shruti S Singhal, Vyoma Shah
Background: Adenoid cystic carcinoma (ACC), a rare tumor of epithelial cell origin, commonly arises from the major salivary glands. Uncommonly it may be found outside the salivary glands and it's especially rare in the nasal cavity. Case presentation: A 71-year female had complaints of swelling at the base of nose, Fine needle aspiration (FNA) from the swelling revealed features of adenoid cystic carcinoma; cell block & IHC for CD-117 was positive. Conclusions: Sino-nasal ACC (SNACC) continues to pose diagnostic and therapeutic challenges to clinicians...
2018: BMC Ear, Nose, and Throat Disorders
Xin Yan Cui, Li Qin Wang, Min Yin, Xi Chen, Mei Ping Lu, Han Zhou, Wei Da Dong, Zhi Bin Chen, Lei Cheng
OBJECTIVES: To investigate the clinical and pathological features of patients with unilateral sinonasal disease (USD). METHODS: A retrospective analysis was completed on 376 adult patients with USD from January 2015 to December 2016. Their presenting symptoms, nasal endoscope, CT scanning, and pathology were analyzed respectively. RESULTS: Among the 267 (71.01%) patients with inflammatory disease, there were 4 pathological types. And there were 8 pathological types in 60 (15...
March 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"