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https://www.readbyqxmd.com/read/28448827/dopamine-cognitive-biases-and-assessment-of-certainty-a-neurocognitive-model-of-delusions
#1
REVIEW
Annabel Broyd, Ryan P Balzan, Todd S Woodward, Paul Allen
This paper examines the evidence that delusions can be explained within the framework of a neurocognitive model of how the brain assesses certainty. Here, 'certainty' refers to both low-level interpretations of one's environment and high-level (conscious) appraisals of one's beliefs and experiences. A model is proposed explaining how the brain systems responsible for assigning certainty might dysfunction, contributing to the cause and maintenance of delusional beliefs. It is suggested that delusions arise through a combination of perturbed striatal dopamine and aberrant salience as well as cognitive biases such as the tendency to jump to conclusions (JTC) and hypersalience of evidence-hypothesis matches...
April 18, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/28447186/comparison-of-the-recovery-response-from-high-intensity-and-high-volume-resistance-exercise-in-trained-men
#2
Sandro Bartolomei, Eliahu Sadres, David D Church, Eliott Arroyo, Joseph A Gordon Iii, Alyssa N Varanoske, Ran Wang, Kyle S Beyer, Leonardo P Oliveira, Jeffrey R Stout, Jay R Hoffman
PURPOSE: The purpose of this study was to compare the physiological responses of a high-volume (HV; 8 sets of 10 repetitions) versus high-intensity (HI; 8 sets of 3 repetitions) exercise protocol in resistance-trained men. METHODS: Twelve men (24.5 ± 4.2 years; 82.3 ± 8.4 kg; 175.2 ± 5.5 cm) with 6.3 ± 3.4 years of resistance training experience performed each protocol in a counterbalanced, randomized order. Performance [counter movement jump peak power (CMJP), isokinetic (ISOK) and isometric leg extension (MVIC), isometric mid-thigh pull (IMTP), and isometric squat (ISQ)] and muscle morphological [cross-sectional area (CSA) of vastus lateralis] assessments were performed at baseline (BL), 30-min (P-30 min), 24-h (P-24 h), 48-h (P-48 h), and 72-h (P-72 h) post-exercise for each testing session...
April 26, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28446669/salivary-blockade-protects-the-lower-respiratory-tract-of-mice-from-lethal-influenza
#3
Karen Ivinson, Georgia Deliyannis, Leanne McNabb, Lara Grollo, Brad Gilbertson, David Jackson, Lorena E Brown
It is possible to model progression of influenza virus from the upper respiratory tract to the lower respiratory tract in the mouse using viral inoculum delivered in a restricted manner to the nose. In this model, infection with the A/Udorn/307/72 (Udorn) strain of virus results ultimately in high viral titres in both the trachea and lungs. In contrast, the A/Puerto Rico/8/34 (PR8) strain causes an infection that is almost entirely limited to the nasal passages. The factors that govern the progression of virus down the respiratory tract are not well understood...
April 26, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28446620/how-to-win-the-hiv-1-drug-resistance-hurdle-race-running-faster-or-jumping-higher
#4
REVIEW
Anna Garbelli, Valentina Riva, Emmanuele Crespan, Giovanni Maga
Infections by the human immunodeficiency virus type 1 (HIV-1), the causative agent of the acquired immunodeficiency syndrome (AIDS), are still totaling an appalling 36.7 millions worldwide, with 1.1 million AIDS deaths/year and a similar number of yearly new infections. All this, in spite of the discovery of HIV-1 as the AIDS etiological agent more than 30 years ago and the introduction of an effective combinatorial antiretroviral therapy (cART), able to control disease progression, more than 20 years ago. Although very effective, current cART is plagued by the emergence of drug-resistant viral variants and most of the efforts in the development of novel direct-acting antiviral agents (DAAs) against HIV-1 have been devoted toward the fighting of resistance...
April 26, 2017: Biochemical Journal
https://www.readbyqxmd.com/read/28442780/the-effect-of-body-composition-and-serum-inflammatory-markers-on-the-functional-muscle-bone-unit-in-premenopausal-women
#5
S M Mueller, I Herter-Aeberli, A C Cepeda-Lopez, M Flück, H H Jung, M Toigo
BACKGROUND/OBJECTIVES: A number of recent studies dealing with the relationship between the effects of high body mass (BM) and fat mass (FM) on bone mass and strength exhibit a range of contrasting variations in their findings. These diverse findings have led to an ongoing controversy as to whether high BM and FM positively or negatively affect bone mass and strength. Excessive fat mass and the associated low-grade inflammation might overturn the higher mechanical stimulus arising from a higher body mass...
April 26, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28441059/effectiveness-of-neuromuscular-training-based-on-the-neuromuscular-risk-profile
#6
Timothy E Hewett, Kevin R Ford, Yingying Y Xu, Jane Khoury, Gregory D Myer
BACKGROUND: The effects of targeted neuromuscular training (TNMT) on movement biomechanics associated with the risk of anterior cruciate ligament (ACL) injuries are currently unknown. Purpose/Hypotheses: To determine the effectiveness of TNMT specifically designed to increase trunk control and hip strength. The hypotheses were that (1) TNMT would decrease biomechanical and neuromuscular factors related to an increased ACL injury risk and (2) TNMT would decrease these biomechanical and neuromuscular factors to a greater extent in athletes identified as being at a high risk for future ACL injuries...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28433808/comparisons-of-hip-strength-and-countermovement-jump-height-in-elite-tennis-players-with-and-without-acute-history-of-groin-injuries
#7
V Moreno-Pérez, A Lopez-Valenciano, D Barbado, J Moreside, J L L Elvira, F J Vera-Garcia
BACKGROUND: Despite the high groin-injury (GI) prevalence in tennis, no studies have assessed the extent to which intrinsic groin injury risk factors, such as hip muscle strength, have recovered in elite tennis players with a history of previous GI. OBJECTIVE: To investigate whether elite tennis players with a history of GI show differences in hip strength and jump height between injured and uninjured limbs and compared with dominant limb in tennis players without history of acute groin-injuries (NGI)...
April 13, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28428033/a-critical-analysis-of-limb-symmetry-indices-of-hop-tests-in-athletes-after-anterior-cruciate-ligament-reconstruction-a-case-control-study
#8
Alli Gokeler, Wouter Welling, Anne Benjaminse, Koen Lemmink, Romain Seil, Stefano Zaffagnini
BACKGROUND: Hop tests are frequently used to determine return to sports (RTS) after anterior cruciate ligament reconstruction (ACLR). Given that bilateral deficits are present after ACLR, this may result in a falsely high limb symmetry index (LSI), since LSI is calculated as a ratio between the values of the limbs. HYPOTHESIS: Athletes after ACLR would achieve LSI > 90% for the hop test. Secondly, athletes after ACLR demonstrate decreased jump distance on the single hop for distance (SLH) and triple leg hop for distance (TLH) and decreased number of hops for the side hop (SH) for both involved and uninvolved limbs compared to normative data of sex, age and type of sports matched healthy athletes...
April 17, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28426514/comparison-of-the-hang-high-pull-and-loaded-jump-squat-for-the-development-of-vertical-jump-and-isometric-force-time-characteristics
#9
Dustin J Oranchuk, Tracey L Robinson, Zachary J Switaj, Eric J Drinkwater
Weightlifting movements have high skill demands and require expert coaching. Loaded jumps have a comparably lower skill demand, but may be similarly effective for improving explosive performance. The purpose of this study was to compare vertical jump performance, isometric force, and rate of force development (RFD) following a ten-week intervention employing the hang high-pull (hang-pull) or trap-bar jump squat (jump-squat). Eighteen NCAA Division II swimmers (8 males, 10 females) with at least one year of resistance training experience volunteered to participate...
April 15, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28424312/archer-fish-jumping-prey-capture-kinematics-and-hydrodynamics
#10
Anna M Shih, Leah Mendelson, Alexandra H Techet
Smallscale archer fish, Toxotes microlepis, are best known for spitting jets of water to capture prey, but also hunt by jumping out of the water to heights of up to 2.5 body lengths. In this study, high-speed imaging and particle image velocimetry were used to characterize the kinematics and hydrodynamics of this jumping behavior. Jumping used a set of kinematics distinct from those of in-water feeding strikes and was segmented into three phases: (1) hovering to sight prey at the surface, (2) rapid upward thrust production and (3) gliding to the prey once out of the water...
April 15, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28422586/the-reactive-strength-index-reflects-vertical-stiffness-during-drop-jumps
#11
Kristof Kipp, Michael T Kiely, Matthew D Giordanelli, Philip J Malloy, Christopher F Geiser
The reactive strength index (RSI) is often used to quantify drop jump (DJ) performance; however, not much is known about the biomechanical determinants of the RSI. The purpose of this study was to investigate the correlations between the RSI and several biomechanical variables calculated from DJ performed with different initial drop heights. Twelve, male NCAA DI basketball players performed DJ from drop heights of 30, 45, and 60 cm. Force plates were used to calculate DJ performance parameters (i.e., DJ height, contact time, and RSI) and DJ biomechanical variables (i...
April 19, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28422525/soccer-match-play-represents-an-important-component-of-the-power-training-stimulus-in-premier-league-players
#12
Ryland Morgans, Rocco Di Michele, Barry Drust
PURPOSE: Competitive match-play is a dominant component of the physical load completed by soccer players within a training micro-cycle. Characterising the temporal disruption in homeostasis that follows exercise may provide some insight into the potential for match-play to elicit an adaptive response. METHODS: Countermovement jump (CMJ) performance was characterised 3 days post-match for 15 outfield players from an English Premier League soccer team (age: 25.8 ± 4...
April 19, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28422183/enhanced-superconductivity-accompanying-a-lifshitz-transition-in-electron-doped-fese-monolayer
#13
X Shi, Z-Q Han, X-L Peng, P Richard, T Qian, X-X Wu, M-W Qiu, S C Wang, J P Hu, Y-J Sun, H Ding
The origin of enhanced superconductivity over 50 K in the recently discovered FeSe monolayer films grown on SrTiO3 (STO), as compared to 8 K in bulk FeSe, is intensely debated. As with the ferrochalcogenides AxFe2-ySe2 and potassium-doped FeSe, which also have a relatively high-superconducting critical temperature (Tc), the Fermi surface (FS) of the FeSe/STO monolayer films is free of hole-like FS, suggesting that a Lifshitz transition by which these hole FSs vanish may help increasing Tc. However, the fundamental reasons explaining this increase of Tc remain unclear...
April 19, 2017: Nature Communications
https://www.readbyqxmd.com/read/28420999/functional-high-intensity-circuit-training-improves-body-composition-peak-oxygen-uptake-strength-and-alters-certain-dimensions-of-quality-of-life-in-overweight-women
#14
Billy Sperlich, Birgit Wallmann-Sperlich, Christoph Zinner, Valerie Von Stauffenberg, Helena Losert, Hans-Christer Holmberg
The effects of circuit-like functional high-intensity training (CircuitHIIT) alone or in combination with high-volume low-intensity exercise (Circuitcombined) on selected cardio-respiratory and metabolic parameters, body composition, functional strength and the quality of life of overweight women were compared. In this single-center, two-armed randomized, controlled study, overweight women performed 9-weeks (3 sessions·wk(-1)) of either CircuitHIIT (n = 11), or Circuitcombined (n = 8). Peak oxygen uptake and perception of physical pain were increased to a greater extent (p < 0...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28416900/measurement-errors-when-estimating-the-vertical-jump-height-with-flight-time-using-photocell-devices-the-example-of-optojump
#15
A Attia, W Dhahbi, A Chaouachi, J Padulo, D P Wong, K Chamari
Common methods to estimate vertical jump height (VJH) are based on the measurements of flight time (FT) or vertical reaction force. This study aimed to assess the measurement errors when estimating the VJH with flight time using photocell devices in comparison with the gold standard jump height measured by a force plate (FP). The second purpose was to determine the intrinsic reliability of the Optojump photoelectric cells in estimating VJH. For this aim, 20 subjects (age: 22.50±1.24 years) performed maximal vertical jumps in three modalities in randomized order: the squat jump (SJ), counter-movement jump (CMJ), and CMJ with arm swing (CMJarm)...
March 2017: Biology of Sport
https://www.readbyqxmd.com/read/28416635/vprbp-dcaf1-regulates-the-degradation-and-non-proteolytic-activation-of-the-cell-cycle-transcription-factor-foxm1
#16
Xianxi Wang, Anthony Arceci, Kelly Bird, Christine A Mills, Rajarshi Choudhury, Jennifer L Kernan, Chunxiao Zhou, Victoria Bae-Jump, Albert Bowers, Michael J Emanuele
The oncogenic transcription factor FoxM1 plays a vital role in cell cycle progression, is activated in numerous human malignancies and linked to chromosome instability. We characterize here a Cullin4-based E3 ubiquitin ligase and its substrate receptor VprBP/DCAF1 (CRL4(VprBP)) that we show regulate FoxM1 ubiquitylation and degradation. Paradoxically, we also found that the substrate receptor VprBP is a potent FoxM1 activator. VprBP depletion reduces expression of FoxM1 target genes and impairs mitotic entry, whereas ectopic VprBP expression strongly activates a FoxM1 transcriptional reporter...
April 17, 2017: Molecular and Cellular Biology
https://www.readbyqxmd.com/read/28415064/physical-demands-of-multimodal-training-competitions-and-their-relationship-to-measures-of-performance
#17
Andrew R Jagim, Owen Rader, Margaret T Jones, Jonathan M Oliver
Jagim, AR, Rader, O, Jones, MT, and Oliver, JM. Physical demands of multimodal training competitions and their relationship to measures of performance. J Strength Cond Res 31(5): 1212-1220, 2017-The purpose of this study was to identify the physical demands of multimodal training (MMT) competitions and to determine the extent of their relationship to select measures of performance. Eighteen (>1.5 years of strength training experience) men (n = 10) and women (n = 8) (mean ± SD; age: 37.8 ± 10.6 years, height: 172...
May 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28410998/a-retrospective-longitudinal-analysis-of-anthropometric-and-physical-qualities-that-associate-with-adult-career-attainment-in-junior-rugby-league-players
#18
Kevin Till, David Morley, John O'Hara, Ben L Jones, Chris Chapman, Clive B Beggs, Carlton Cooke, Stephen Cobley
OBJECTIVES: To retrospectively compare the longitudinal physical development of junior rugby league players between the Under 13 and 15 age categories in relation to their adult career attainment outcome. DESIGN: Retrospective longitudinal design. METHODS: Fifty-one former junior rugby league players were retrospectively grouped according to their career attainment outcome as adults (i.e., amateur, academy or professional). As juniors, players undertook a physical testing battery on three consecutive annual occasions (Under 13s, 14s, 15s) including height, body mass, sum of four skinfolds, maturation, vertical jump, medicine ball chest throw, 10-60m sprint, agility 505 and estimated V˙O2max ...
March 30, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28409516/relationships-between-fitness-test-and-kicking-velocity-in-young-soccer-players
#19
Víctor Torreblanca-Martínez, José A González-Jurado, Fernando M Otero-Saborido
BACKGROUND: To study the relation between fitness test and kicking velocity in young soccer players, which has not been previously studied in this group of age. METHODS: Ninety eight Under-11 soccer players who belonged to two professional Spanish clubs and two amateur clubs were subjected to sprint test (15 and 30 meters), CMJ (Countermovement Jump), estimation of maximal oxygen intake (VO2max), kicking velocity test, fatigue index of jump height and anthropometrical measures...
April 13, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28409512/immediate-effects-of-different-types-of-stretching-exercises-on-badminton-jump-smash
#20
Hwi S Jang, Daeho Kim, Jihong Park
BACKGOUND: Since different types of stretching exercises may alter athletic performance, we compared the effects of three types of stretching exercises on badminton jump smash. METHODS: Sixteen male collegiate badminton players performed one of three different stretching exercises in a counterbalanced order on different days. Static stretching had seven typical stretches, while dynamic stretching involved nine dynamic movements, and resistance dynamic stretching was performed with weighted vests and dumbbells...
April 13, 2017: Journal of Sports Medicine and Physical Fitness
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