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https://www.readbyqxmd.com/read/28431031/sandbagging-on-the-immediate-post-concussion-assessment-and-cognitive-testing-impact-in-a-high-school-athlete-population
#1
Kathryn L Higgins, Robert L Denney, Arthur Maerlender
The Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) is a computerized neuropsychological test battery commonly used to assess cognitive functioning after a concussion. It is recommended that application of ImPACT utilizes a baseline administration so athletes have an individualized baseline with which to compare post-injury results should they sustain a concussion. It has been suggested that athletes may provide suboptimal effort, called "sandbagging," in order to return to their baseline cognitive scores, and thus to play, more quickly...
May 1, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28430849/performance-and-symptom-validity-testing-as-a-function-of-medical-board-evaluation-in-u-s-military-service-members-with-a-history-of-mild-traumatic-brain-injury
#2
Patrick Armistead-Jehle, Wesley R Cole, Robert L Stegman
Objective: The study was designed to replicate and extend pervious findings demonstrating the high rates of invalid neuropsychological testing in military service members (SMs) with a history of mild traumatic brain injury (mTBI) assessed in the context of a medical evaluation board (MEB). Method: Two hundred thirty-one active duty SMs (61 of which were undergoing an MEB) underwent neuropsychological assessment. Performance validity (Word Memory Test) and symptom validity (MMPI-2-RF) test data were compared across those evaluated within disability (MEB) and clinical contexts...
April 20, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28429733/sites-of-overt-and-covert-attention-define-simultaneous-spatial-reference-centers-for-visuomotor-response
#3
Yang Zhou, Lixin Liang, Yujun Pan, Ning Qian, Mingsha Zhang
The site of overt attention (fixation point) defines a spatial reference center that affects visuomotor response as indicated by the stimulus-response-compatibility (SRC) effect: When subjects press, e.g., a left key to report stimuli, their reaction time is shorter when stimuli appear to the left than to the right of the fixation. Covert attention to a peripheral site appears to define a similar reference center but previous studies did not control for confounding spatiotemporal factors or investigate the relationship between overt- and covert-attention-defined centers...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28429656/baseline-cognitive-test-performance-and-concussion-like-symptoms-among-adolescent-athletes-with-adhd-examining-differences-based-on-medication-use
#4
Nathan E Cook, Donna S Huang, Noah D Silverberg, Brian L Brooks, Bruce Maxwell, Ross Zafonte, Paul D Berkner, Grant L Iverson
OBJECTIVE: Youth with attention deficit hyperactivity disorder (ADHD) perform more poorly on preseason cognitive testing and report more baseline concussion-like symptoms but prior studies have not examined the influence of medication use on test performance or symptom reporting. This study investigated whether medication use is relevant when interpreting baseline ImPACT® results from student athletes with ADHD. METHOD: Participants were 39,247 adolescent athletes, ages 13-18 (mean age = 15...
April 21, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28427898/pharmacist-impact-on-pediatric-vaccination-errors-and-missed-opportunities-in-the-setting-of-clinical-decision-support
#5
Kelly A Wise, Sonya J Sebastian, Anna C Haas-Gehres, Melissa D Moore-Clingenpeel, Kristen E Lamberjack
OBJECTIVE: To determine pharmacist impact on vaccination errors and missed opportunities in the pediatric primary care setting with the presence of clinical decision support (CDS) by comparing a clinic with a pharmacist and CDS to a clinic with CDS alone. DESIGN: A retrospective chart review of patients' electronic medical records compared vaccination errors and missed opportunities between 2 pediatric primary care clinics. SETTING: Two urban, pediatric primary care clinics were selected for the study...
April 17, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28427428/quality-issues-with-malaria-rapid-diagnostic-test-accessories-and-buffer-packaging-findings-from-a-5-country-private-sector-project-in-africa
#6
Steven A Harvey, Sandra Incardona, Nina Martin, Cristina Lussiana, Elizabeth Streat, Stephanie Dolan, Nora Champouillon, Daniel J Kyabayinze, Robert Mugerwa, Grace Nakanwagi, Nancy Njoki, Ratsimandisa Rova, Jane Cunningham
BACKGROUND: Use of antigen-detecting malaria rapid diagnostic tests (RDTs) has increased exponentially over the last decade. WHO's Global Malaria Programme, FIND, and other collaborators have established a quality assurance scheme to guide product selection, lot verification, transport, storage, and training procedures. Recent concerns over the quality of buffer packaging and test accessories suggest a need to include these items in product assessments. This paper describes quality problems with buffer and accessories encountered in a project promoting private sector RDT use in five African countries and suggests steps to avoid or more rapidly identify and resolve such problems...
April 20, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28427133/-effects-of-application-of-vancomycin-in-the-early-stage-of-patients-with-extremely-severe-burn
#7
Z Zhu, G W Cao, J J Bao, Z H Hu, Z Shen, H Tao, B Cao, F Xu
Objective: To evaluate the effects of application of vancomycin in the early stage of patients with extremely severe burn, in order to provide reference to drug for anti-infection treatment in the early stage of patients with extremely severe burn. Methods: Data of 15 patients of Kunshan explosion on August 2nd, 2014, admitted to the Department of Intensive Care in our hospital were retrospectively analyzed. The clinical efficacy of continuously intravenous dripping of vancomycin (combined with imipenem) in the early stage of burns (before and on post burn day 14) was analyzed...
April 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28425726/comparisons-between-the-minnesota-multiphasic-personality-inventory-adolescent-restructured-form-mmpi-a-rf-and-mmpi-a-in-adolescent-psychiatric-inpatients
#8
John M Stokes, David L Pogge, Robert P Archer
This study explored the association between the Minnesota Multiphasic Personality Inventory (MMPI)-Adolescent-Restructured Form (MMPI-A-RF) and the MMPI-Adolescent (MMPI-A) form in a sample of 3,516 adolescents receiving inpatient psychiatric treatment, including 2,798 adolescents meeting validity inclusion cutoffs for both measures. There was 92.5% agreement rate with respect to global identification of cases as valid or invalid and some empirical support for lowering interpretive cutoffs for validity scales on the MMPI-A-RF...
April 20, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28415989/evaluation-of-genotype-mtbdrplus-ver-2-0-line-probe-assay-for-the-detection-of-mdr-tb-in-smear-positive-and-negative-sputum-samples
#9
Abyot Meaza, Abebaw Kebede, Zelalem Yaregal, Zekarias Dagne, Shewki Moga, Bazezew Yenew, Getu Diriba, Helina Molalign, Mengistu Tadesse, Desalegn Adisse, Muluwork Getahun, Kassu Desta
BACKGROUND: Multi drug resistant tuberculosis (MDR-TB) poses formidable challenges to TB control due to its complex diagnostic and treatment challenges and often associated with a high rate of mortality. Accurate and rapid detection of MDR-TB is critical for timely initiation of treatment. Line Probe Assay (LPA) is a qualitative in vitro diagnostic test based on DNA-STRIP technology for the identification of the M. tuberculosis complex and its resistance to rifampicin (RMP) and/or isoniazid (INH)...
April 17, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28415976/smrt-genome-assembly-corrects-reference-errors-resolving-the-genetic-basis-of-virulence-in-mycobacterium-tuberculosis
#10
Afif Elghraoui, Samuel J Modlin, Faramarz Valafar
BACKGROUND: The genetic basis of virulence in Mycobacterium tuberculosis has been investigated through genome comparisons of virulent (H37Rv) and attenuated (H37Ra) sister strains. Such analysis, however, relies heavily on the accuracy of the sequences. While the H37Rv reference genome has had several corrections to date, that of H37Ra is unmodified since its original publication. RESULTS: Here, we report the assembly and finishing of the H37Ra genome from single-molecule, real-time (SMRT) sequencing...
April 17, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28407527/top-down-control-over-feedback-processing-the-probability-of-valid-feedback-affects-feedback-related-brain-activity
#11
Benjamin Ernst, Marco Steinhauser
Adaptive decision-making requires that feedback about decision outcomes is adequately processed. Recent studies have shown that fronto-central event-related potentials (ERPs) are sensitive to feedback valence and can be used as an index of feedback processing. The present study investigated whether the processes involved in feedback evaluation are affected by top-down mechanisms driven by knowledge about feedback validity. In a simple decision task, participants had to make use of feedback to learn which one of two stimuli was associated with a reward in a later test phase...
April 10, 2017: Brain and Cognition
https://www.readbyqxmd.com/read/28406501/culture-dependent-enumeration-methods-failed-to-simultaneously-detect-disinfectant-injured-and-genetically-modified-escherichia-coli-in-drinking-water
#12
Jing Li, Lu Liu, Dong Yang, Wei-Li Liu, Zhi-Qiang Shen, Hong-Mei Qu, Zhi-Gang Qiu, Ai-Ming Hou, Da-Ning Wang, Chen-Shi Ding, Jun-Wen Li, Jian-Hua Guo, Min Jin
Underestimation of Escherichia coli in drinking water, an indicator microorganism of sanitary risk, may result in potential risks of waterborne diseases. However, the detection of disinfectant-injured or genetically modified (GM) E. coli has been largely overlooked so far. To evaluate the accuracy of culture-dependent enumeration with regard to disinfectant-injured and GM E. coli, chlorine- or ozone-injured wild-type (WT) and GM E. coli were prepared and characterized. Then, water samples contaminated with these E...
April 13, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28403015/hr-hpv-e6-e7-mrna-in-situ-hybridization-validation-against-pcr-dna-in-situ-hybridization-and-p16-immunohistochemistry-in-102-samples-of-cervical-vulvar-anal-and-head-and-neck-neoplasia
#13
Anne M Mills, Dawn C Dirks, Melinda D Poulter, Stacey E Mills, Mark H Stoler
Dysregulated expression of oncogenic types of E6 and E7 is necessary for human papillomavirus (HPV)-driven carcinogenesis. An HPV E6/E7 mRNA in situ hybridization (ISH) assay covering 18 common high-risk types ("HR-RISH," aka HR-HPV RNA18 ISH) has not been extensively studied in the anogenital tract or validated on automated technology. We herein compare HR-RISH to DNA polymerase chain reaction (PCR), p16 immunohistochemistry, and a previously available HPV DNA ISH assay in HPV-related anogenital and head and neck (H&N) neoplasia...
May 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28401405/patient-choice-modelling-how-do-patients-choose-their-hospitals
#14
Honora Smith, Christine Currie, Pornpimol Chaiwuttisak, Andreas Kyprianou
As an aid to predicting future hospital admissions, we compare use of the Multinomial Logit and the Utility Maximising Nested Logit models to describe how patients choose their hospitals. The models are fitted to real data from Derbyshire, United Kingdom, which lists the postcodes of more than 200,000 admissions to six different local hospitals. Both elective and emergency admissions are analysed for this mixed urban/rural area. For characteristics that may affect a patient's choice of hospital, we consider the distance of the patient from the hospital, the number of beds at the hospital and the number of car parking spaces available at the hospital, as well as several statistics publicly available on National Health Service (NHS) websites: an average waiting time, the patient survey score for ward cleanliness, the patient safety score and the inpatient survey score for overall care...
April 11, 2017: Health Care Management Science
https://www.readbyqxmd.com/read/28398224/inertial-sensor-based-robust-gait-analysis-in-non-hospital-settings-for-neurological-disorders
#15
Can Tunca, Nezihe Pehlivan, Nağme Ak, Bert Arnrich, Gülüstü Salur, Cem Ersoy
The gold standards for gait analysis are instrumented walkways and marker-based motion capture systems, which require costly infrastructure and are only available in hospitals and specialized gait clinics. Even though the completeness and the accuracy of these systems are unquestionable, a mobile and pervasive gait analysis alternative suitable for non-hospital settings is a clinical necessity. Using inertial sensors for gait analysis has been well explored in the literature with promising results. However, the majority of the existing work does not consider realistic conditions where data collection and sensor placement imperfections are imminent...
April 11, 2017: Sensors
https://www.readbyqxmd.com/read/28397175/detecting-hijacked-journals-by-using-classification-algorithms
#16
Mona Andoohgin Shahri, Mohammad Davarpanah Jazi, Glenn Borchardt, Mehdi Dadkhah
Invalid journals are recent challenges in the academic world and many researchers are unacquainted with the phenomenon. The number of victims appears to be accelerating. Researchers might be suspicious of predatory journals because they have unfamiliar names, but hijacked journals are imitations of well-known, reputable journals whose websites have been hijacked. Hijacked journals issue calls for papers via generally laudatory emails that delude researchers into paying exorbitant page charges for publication in a nonexistent journal...
April 10, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/28397174/perceptions-of-chinese-biomedical-researchers-towards-academic-misconduct-a-comparison-between-2015-and-2010
#17
Qing-Jiao Liao, Yuan-Yuan Zhang, Yu-Chen Fan, Ming-Hua Zheng, Yu Bai, Guy D Eslick, Xing-Xiang He, Shi-Bing Zhang, Harry Hua-Xiang Xia, Hua He
Publications by Chinese researchers in scientific journals have dramatically increased over the past decade; however, academic misconduct also becomes more prevalent in the country. The aim of this prospective study was to understand the perceptions of Chinese biomedical researchers towards academic misconduct and the trend from 2010 to 2015. A questionnaire comprising 10 questions was designed and then validated by ten biomedical researchers in China. In the years 2010 and 2015, respectively, the questionnaire was sent as a survey to biomedical researchers at teaching hospitals, universities, and medical institutes in mainland China...
April 10, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/28395492/-the-clinical-features-and-efficacy-of-patients-with-geotropic-direction-changing-positional-nystagmus
#18
H Peng, L Y Wang, H T Song, W N Huang
Objective: The purpose of this study was to observe the clinical characteristics of two types of geotropic direction-changing positional nystagmus, the transient(nystagmus time <1 min) and the persistent(nystagmus time > 1 min), and to evaluate the efficacy of the barbecue roll maneuver. Methods: A total of 105 cases diagnosed by supine roll test were studied, which including 35 males and 70 females and the average age was (56.9±14.6)years. There were 70 transient geotropic DCPN and 35 persistent geotropic DCPN...
March 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28391774/exploring-the-sensitivity-of-the-personality-assessment-inventory-symptom-validity-tests-in-detecting-response-bias-in-a-mixed-neuropsychological-outpatient-sample
#19
Owen J Gaasedelen, Douglas M Whiteside, Michael Basso
OBJECTIVE: Few studies have evaluated the symptom validity tests (SVTs) within the Personality Assessment Inventory (PAI) in a neuropsychological assessment context. Accordingly, the present study explored the accuracy of PAI SVTs in identifying exaggerated cognitive dysfunction in a mixed sample of outpatients referred for neuropsychological assessment. METHOD: Participants who failed two or more Performance Validity Tests (PVTs) were classified as having exaggerated cognitive dysfunction (n = 49)...
April 10, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28387219/comments-on-evidence-of-the-hydrogen-release-mechanism-in-bulk-mgh2
#20
Alexander Surrey, Kornelius Nielsch, Bernd Rellinghaus
The effect of an electron beam induced dehydrogenation of MgH2 in the transmission electron microscope (TEM) is largely underestimated by Nogita et al., and led the authors to a misinterpretation of their TEM observations. Firstly, the selected area diffraction (SAD) pattern is falsely interpreted. A re-evaluation of the SAD pattern reveals that no MgH2 is present in the sample, but that it rather consists of Mg and MgO only. Secondly, the transformation of the sample upon in-situ heating in the TEM cannot be ascribed to dehydrogenation, but is rather to be explained by the (nanoscale) Kirkendall effect, which leads to the formation of hollow MgO shells without any metallic Mg in their cores...
April 7, 2017: Scientific Reports
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