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https://www.readbyqxmd.com/read/28805235/how-do-singapore-patients-view-post-anaesthesia-adverse-outcomes-a-single-centre-willingness-to-pay-study
#1
Xinqi Look, May Un Sam Mok, Yan Sheng Tay, Hairil Rizal Abdullah
INTRODUCTION: Knowing how patients value quality of anaesthesia helps anaesthesiologists to customise their service. However, generalising findings from Western population-based willingness-to-pay (WTP) studies across different cultures and societies might overlook several important contextualised understandings of anaesthesia experience for Singapore patients. This study aimed to capture the Singapore perspective of undesired post-anaesthesia outcomes. METHODS: 132 patients recruited in the pre-anaesthetic evaluation clinic were given questionnaires describing ten possible post-anaesthetic outcomes to rank for undesirability and assign relative value through proportioning hypothetical SGD 100 to avoid their occurrence...
August 14, 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28804861/trends-and-socioeconomic-inequalities-in-amenable-mortality-in-switzerland-with-international-comparisons
#2
Anita Feller, Kurt Schmidlin, Kerri M Clough-Gorr
BACKGROUND: Amenable mortality is a composite measure of deaths from conditions that might be avoided by timely and effective healthcare. It was developed as an indicator to study health care quality. METHODS: We calculated mortality rates for the population aged 0-74 years for the time-period 1996-2010 and the following groups of causes of death: amenable conditions, ischaemic heart diseases (IHD, defined as partly amenable) and remaining conditions. We compared the Swiss results with those published for 16 other high-income countries...
August 14, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28802104/results-of-the-second-national-forest-soil-inventory-in-germany-interpretation-of-level-and-stock-profiles-for-pcdd-f-and-pcb-in-terms-of-vegetation-and-humus-type
#3
Marchela Pandelova, Bernhard Henkelmann, Bernd M Bussian, Karl-Werner Schramm
Polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) were detected in 86 humic topsoil layers and in a subset of 11 randomly selected top mineral forest soils at the depths of 0-5cm and 5-10cm collected from different federal states of Germany. The distribution of these persistent organic pollutants (POPs) in humic topsoils with respect to vegetation cover (coniferous vs. deciduous vs. mixed), total organic carbon (TOC), altitude and latitude data was investigated...
August 9, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28796060/candidate-genes-investigation-for-severe-nonalcoholic-fatty-liver-disease-based-on-bioinformatics-analysis
#4
Shan Qi, Changhong Wang, Chunfu Li, Pu Wang, Minghui Liu
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver condition worldwide. However, its etiology and fundamental pathophysiology for the disease process are poorly understood. In this study, we thus used bioinformatics to identify candidate genes potentially causative of severe NAFLD. METHODS: Gene expression profile data GSE49541 were downloaded from the Gene Expression Omnibus database. Tissues samples from 32 severe and 40 mild NAFLD patients were evaluated to identify differentially expressed genes (DEGs) between the 2 groups, followed by analyses of Gene Ontology (GO) functions and Kyoto Encyclopedia of Genes and Genomes pathways...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28795079/towards-shot-noise-limited-diffraction-experiments-with-table-top-femtosecond-hard-x-ray-sources
#5
Marcel Holtz, Christoph Hauf, Jannick Weisshaupt, Antonio-Andres Hernandez Salvador, Michael Woerner, Thomas Elsaesser
Table-top laser-driven hard x-ray sources with kilohertz repetition rates are an attractive alternative to large-scale accelerator-based systems and have found widespread applications in x-ray studies of ultrafast structural dynamics. Hard x-ray pulses of 100 fs duration have been generated at the Cu K α wavelength with a photon flux of up to 10(9) photons per pulse into the full solid angle, perfectly synchronized to the sub-100-fs optical pulses from the driving laser system. Based on spontaneous x-ray emission, such sources display a particular noise behavior which impacts the sensitivity of x-ray diffraction experiments...
September 2017: Structural Dynamics (Melville, N.Y.)
https://www.readbyqxmd.com/read/28792966/maternal-exposure-to-an-environmentally-relevant-dose-of-triclocarban-results-in-perinatal-exposure-and-potential-alterations-in-offspring-development-in-the-mouse-model
#6
Heather A Enright, Miranda J S Falso, Michael A Malfatti, Victoria Lao, Edward A Kuhn, Nicholas Hum, Yilan Shi, Ana Paula Sales, Kurt W Haack, Kristen S Kulp, Bruce A Buchholz, Gabriela G Loots, Graham Bench, Kenneth W Turteltaub
Triclocarban (TCC) is among the top 10 most commonly detected wastewater contaminants in both concentration and frequency. Its presence in water, as well as its propensity to bioaccumulate, has raised numerous questions about potential endocrine and developmental effects. Here, we investigated whether exposure to an environmentally relevant concentration of TCC could result in transfer from mother to offspring in CD-1 mice during gestation and lactation using accelerator mass spectrometry (AMS). 14C-TCC (100 nM) was administered to dams through drinking water up to gestation day 18, or from birth to post-natal day 10...
2017: PloS One
https://www.readbyqxmd.com/read/28783031/patterns-in-the-distribution-and-directional-asymmetry-of-fleas-living-on-the-northern-white-breasted-hedgehog-erinaceus-roumanicus
#7
Krzysztof Dudek, Gabor Foldvari, Viktoria Majlathova, Igor Majlath, Krisztina Rigo, Viktor Molnar, Maria Toth, Lukasz Jankowiak, Piotr Tryjanowski
Fleas infecting northern white-breasted hedgehogs, Erinaceus roumanicus (Barrett-Hamilton), collected from 2009-2011 in Budapest (Hungary) were studied. A total of 305 white-breasted hedgehogs were captured and 1,251 fleas were collected. The flea community comprised two species, the hedgehog flea Archaeopsylla erinacei (Bouche, 1835) and the dog flea Ctenocephalides canis (Curtis, 1826), although the latter was only found on three hedgehogs. Fleas were found on half of the host specimens (51%; n = 156) where their distribution was strongly aggregated...
August 4, 2017: Folia Parasitologica
https://www.readbyqxmd.com/read/28782115/optical-coherence-tomography-image-guided-smart-laser-knife-for-surgery
#8
Nitesh Katta, Austin B McElroy, Arnold D Estrada, Thomas E Milner
BACKGROUND AND OBJECTIVE: Surgical oncology can benefit from specialized tools that enhance imaging and enable precise cutting and removal of tissue without damage to adjacent structures. The combination of high-resolution, fast optical coherence tomography (OCT) co-aligned with a nanosecond pulsed thulium (Tm) laser offers advantages over conventional surgical laser systems. Tm lasers provide superior beam quality, high volumetric tissue removal rates with minimal residual thermal footprint in tissue, enabling a reduction in unwanted damage to delicate adjacent sub-surface structures such as nerves or micro-vessels...
August 7, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28780873/control-of-rectification-in-molecular-junctions-contact-effects-and-molecular-signature
#9
Quyen Van Nguyen, Pascal Martin, Denis Frath, Maria Luisa Della Rocca, Frederic Lafolet, Clément Barraud, Philippe Lafarge, Vineetha Mukundan, David James, Richard L McCreery, Jean-Christophe Lacroix
Thin layers of oligomers with thickness between 7 and 9 nm were deposited on flat gold electrode surfaces by electrochemical reduction of diazonium reagents, then a Ti(2 nm)/Au top contact was applied to complete a solid-state molecular junction. The molecular layers investigated included donor molecules with relatively high energy HOMO, molecules with high HOMO-LUMO gaps and acceptor molecules with low energy LUMO and terminal alkyl chain. Using an oligo(bisthienylbenzene) based layer, a molecule whose HOMO energy level in vacuum is close to the fermi level of the gold bottom electrode, the devices exhibit robust and highly reproducible rectification ratios above 1000 at low voltage (2...
August 6, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28777029/characterizing-smartphone-engagement-for-schizophrenia-results-of-a-naturalist-mobile-health-study
#10
John Torous, Patrick Staples, Linda Slaters, Jared Adams, Luis Sandoval, J P Onnela, Matcheri Keshavan
INTRODUCTION: Despite growing interest in smartphone apps for schizophrenia, little is known about how these apps are utilized in the real world. Understanding how app users are engaging with these tools outside of the confines of traditional clinical studies offers an important information on who is most likely to use apps and what type of data they are willing to share. METHODS: The Schizophrenia and Related Disorders Alliance of America, in partnership with Self Care Catalyst, has created a smartphone app for schizophrenia that is free and publically available on both Apple iTunes and Google Android Play stores...
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28772309/uvemaster-a-mobile-app-based-decision-support-system-for-the-differential-diagnosis-of-uveitis
#11
Jose A Gegundez-Fernandez, Jose I Fernandez-Vigo, David Diaz-Valle, Rosalia Mendez-Fernandez, Ricardo Cuiña-Sardiña, Enrique Santos-Bueso, Jose M Benitez-Del-Castillo
Purpose: To examine the diagnostic accuracy and performance of Uvemaster, a mobile application (app) or diagnostic decision support system (DDSS) for uveitis. The app contains a large database of knowledge including 88 uveitis syndromes each with 76 clinical items, both ocular and systemic (total 6688) and their respective prevalences, and displays a differential diagnoses list (DDL) ordered by sensitivity, specificity, or positive predictive value (PPV). Methods: In this retrospective case-series study, diagnostic accuracy (percentage of cases for which a correct diagnosis was obtained) and performance (percentage of cases for which a specific diagnosis was obtained) were determined in reported series of patients originally diagnosed by a uveitis specialist with specific uveitis (N = 88) and idiopathic uveitis (N = 71), respectively...
August 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28765803/most-cited-publications-in-cervical-spine-surgery
#12
Yu Chao Lee, Francis Brooks, Simon Sandler, Yun-Hom Yau, Michael Selby, Brian Freeman
PURPOSE: The purpose of this study is to perform a citation analysis on the most frequently cited articles in the topic of cervical spine surgery and report on the top 100 most cited publication in this topic. METHODS: We used the Thomson Reuters Web of Science to search citations of all articles from 1945 to 2015 relevant to cervical spine surgery and ranked them according to the number of citations. The 100 most cited articles that matched the search criteria were further analyzed by number of citations, first author, journal, year of publication, country and institution of origin...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28764080/supramolecular-solvents-combined-with-layered-double-hydroxide-coated-magnetic-nanoparticles-for-extraction-of-bisphenols-and-4-tert-octylphenol-from-fruit-juices
#13
Dezhi Yang, Xiaolan Li, Dongling Meng, Meng Wang, Yaling Yang
A magnesium-aluminum layered double hydroxides coated on magnetic nanoparticles (Fe3O4@MgAl-LDHs NPs) combined with the supramolecular solvents (SUPRASs) as the magnetic supramolecular fluids were successfully applied to the extraction and determination of four phenolic compounds (Bisphenol-A (BPA), bisphenol-AF (BPAF), tetrabromobisphenol-A (TBBPA) and 4-tert-octylphenol (4-TOP)). Magnetic supramolecular fluids (ferrofluids) composites were prepared through adding the mixture of n-octanol and tetrahydrofuran in distilled water as the supramolecular solvents into the solution containing magnetic Fe3O4@MgAl-LDHs NPs...
December 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28761373/chronic-constriction-injury-of-sciatic-nerve-changes-circular-rna-expression-in-rat-spinal-dorsal-horn
#14
Song Cao, Wenwen Deng, Ying Li, Bangyong Qin, Lin Zhang, Shouyang Yu, Peng Xie, Zhi Xiao, Tian Yu
BACKGROUND: Mechanisms of neuropathic pain are still largely unknown. Molecular changes in spinal dorsal horn may contribute to the initiation and development of neuropathic pain. Circular RNAs (circRNAs) have been identified as microRNA sponges and involved in various biological processes, but whether their expression profile changes in neuropathic pain condition is not reported. METHODS: To test whether neuropathic pain influences circRNA expression, we developed a sciatic chronic constriction injury (CCI) model in rats...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28760165/diagnostic-imaging-in-disasters-a-bibliometric-analysis
#15
Bo Gong, Mohammed F Mohammed, Savvas Nicolaou, Muazzam Nasrullah, Bruce B Forster, Faisal Khosa
OBJECTIVE: To investigate the role of diagnostic imaging in the clinical diagnosis, treatment, and follow-up management of patients in response to disasters. METHODS: A MEDLINE (OVID) search of original research articles identified 177 articles on this topic published since 2000. A bibliometric analysis was conducted on the top 100 articles ranked by average yearly citation. RESULTS: The most frequently studied disaster categories were disease outbreak (55 articles), armed conflict (23 articles), terrorist incident (10 articles), and earthquake (7 articles)...
August 1, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28759536/ranking-prediction-model-using-the-competition-record-of-ladies-professional-golf-association-players
#16
Jin Seok Chae, Jin Park, Wi-Young So
The purpose of this study was to suggest a ranking prediction model using the competition record of the Ladies Professional Golf Association (LPGA) players. The top 100 players on the tour money list from the 2013-2016 US Open were analyzed in this model. Stepwise regression analysis was conducted to examine the effect of performance and independent variables (i.e., driving accuracy, green in regulation, putts per round, driving distance, percentage of sand saves, par-3 average, par-4 average, par-5 average, birdies average, and eagle average) on dependent variables (i...
July 28, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28758260/vapomechanically-responsive-motion-of-microchannel-programmed-actuators
#17
Lidong Zhang, Pancˇe Naumov, Xuemin Du, Zhigao Hu, Juan Wang
Materials that respond rapidly and reversibly to external stimuli currently stand among the top choices as actuators for real-world applications. Here, a series of programmable actuators fabricated as single- or bilayer elements is described that can reversibly respond to minute concentrations of acetone vapors. By using templates, microchannel structures are replicated onto the surface of two highly elastic polymers, polyvinylidene fluoride (PVDF) and polyvinyl alcohol, to induce chiral coiling upon exposure to acetone vapors...
July 31, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28756294/vitamin-d-cod-liver-oil-sunshine-and-phototherapy-safe-effective-and-forgotten-tools-for-treating-and-curing-tuberculosis-infections-a-comprehensive-review
#18
REVIEW
Patrick J McCullough, Douglas S Lehrer
Tuberculosis remains an epidemic throughout the world, with over 2 billion people, or more than one third of the world's population, infected with TB. In 2015, there were an estimated 10.4 million new cases of tuberculosis, and 1.8 million deaths, making TB one of the top ten causes of death worldwide. Approximately 95% of new TB cases occur in developing countries, where the costs of treatment force many patients and their families into poverty. The United Nations and the World Health Organization are working to end this global epidemic...
July 26, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28753682/a-new-computational-strategy-for-identifying-essential-proteins-based-on-network-topological-properties-and-biological-information
#19
Chao Qin, Yongqi Sun, Yadong Dong
Essential proteins are the proteins that are indispensable to the survival and development of an organism. Deleting a single essential protein will cause lethality or infertility. Identifying and analysing essential proteins are key to understanding the molecular mechanisms of living cells. There are two types of methods for predicting essential proteins: experimental methods, which require considerable time and resources, and computational methods, which overcome the shortcomings of experimental methods. However, the prediction accuracy of computational methods for essential proteins requires further improvement...
2017: PloS One
https://www.readbyqxmd.com/read/28747877/combining-multiple-resting-state-fmri-features-during-classification-optimized-frameworks-and-their-application-to-nicotine-addiction
#20
Xiaoyu Ding, Yihong Yang, Elliot A Stein, Thomas J Ross
Machine learning techniques have been applied to resting-state fMRI data to predict neurological or neuropsychiatric disease states. Existing studies have used either a single type of resting-state feature or a few feature types (<4) in the prediction model. However, resting-state data can be processed in many different ways, yielding different feature types containing complementary and/or novel information, leaving uncertain the most informative features to provide to the classifier. In this study, multiple resting-state features were calculated from two main analytical categories: local measures and network measures...
2017: Frontiers in Human Neuroscience
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