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https://www.readbyqxmd.com/read/29449412/hemodynamic-characteristics-in-significant-symptomatic-and-asymptomatic-primary-mitral-valve-regurgitation-at-rest-and-during-exercise
#1
Rine Bakkestrøm, Ann Banke, Nicolaj L Christensen, Redi Pecini, Akhmadjon Irmukhamedov, Mads Andersen, Barry A Borlaug, Jacob E Møller
BACKGROUND: In severe asymptomatic primary mitral valve regurgitation without risk factors, surgery strategy is controversial. We sought to clarify whether being symptomatic corresponds to the hemodynamic burden and reduced exercise capacity. A better understanding of this may contribute to optimize timing of surgery. METHODS AND RESULTS: Subjects with asymptomatic (New York Heart Association functional class I, n=29) or symptomatic (New York Heart Association functional class II and III, n=28) significant primary mitral valve regurgitation (effective regurgitant orifice, ≥0...
February 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29444998/treatment-of-aortic-stenosis-with-a-self-expanding-resheathable-transcatheter-valve-one-year-results-of-the-international-multicenter-portico-transcatheter-aortic-valve-implantation-system-study
#2
Axel Linke, David Holzhey, Helge Möllmann, Ganesh Manoharan, Ulrich Schäfer, Christian Frerker, Stephen G Worthley, A J van Boven, Simon Redwood, Jan Kovac, Christian Butter, Lars Søndergaard, Alexander Lauten, Gerhard Schymik, Thomas Walther
BACKGROUND: The aim of the Portico TAVI (transcatheter aortic valve implantation) system study was to evaluate outcomes ≤1 year after implantation of a novel resheathable, self-expanding TAVI system in a multicenter patient population with severe aortic stenosis (AS). METHODS AND RESULTS: High-risk patients (n=222) with symptomatic severe AS (mean age, 83.0±4.6 years; 74.3% women) were enrolled across 12 centers in Europe and Australia. The study's primary end point was all-cause mortality at 30 days...
February 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29440192/impact-of-anticoagulation-therapy-on-valve-haemodynamic-deterioration-following-transcatheter-aortic-valve-replacement
#3
María Del Trigo, Antonio J Muñoz-García, Azeem Latib, Vincent Auffret, Harindra C Wijeysundera, Luis Nombela-Franco, Enrique Gutierrez, Asim N Cheema, Vicenç Serra, Ignacio J Amat-Santos, Joelle Kefer, Luis Miguel Benitez, Florence Leclercq, Antonio Mangieri, Hervé Le Breton, Pilar Jiménez-Quevedo, Bruno Garcia Del Blanco, Antonio Dager, Omar Abdul-Jawad Altisent, Rishi Puri, Philippe Pibarot, Josep Rodés-Cabau
OBJECTIVE: To evaluate the changes in transvalvular gradients and the incidence of valve haemodynamic deterioration (VHD) following transcatheter aortic valve replacement (TAVR), according to use of anticoagulation therapy. METHODS AND RESULTS: This multicentre study included 2466 patients (46% men; mean age 81±7 years) who underwent TAVR with echocardiography performed at 12-month follow-up. Anticoagulation therapy was used in 707 patients (28.7%) following TAVR (AC group)...
February 13, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29438721/changes-in-left-ventricular-systolic-and-diastolic-function-on-serial-echocardiography-after-out-of-hospital-cardiac-arrest
#4
Jacob C Jentzer, Nandan S Anavekar, Sunil V Mankad, Roger D White, Kianoush B Kashani, Gregory W Barsness, Alejandro A Rabinstein, Sorin V Pislaru
AIM: Reversible myocardial dysfunction is common after out-of-hospital cardiac arrest (OHCA). The aim of this study was to determine if changes on serial transthoracic echocardiography (TTE) can predict long-term mortality in OHCA subjects. METHODS: This is a single-center historical cohort study of OHCA subjects undergoing targeted temperature management who received >1 TTE during hospitalization. Two-dimensional and Doppler parameters of systolic and diastolic function were compared between paired TTE...
February 10, 2018: Resuscitation
https://www.readbyqxmd.com/read/29438511/prediction-of-ischaemic-stroke-in-non-valvular-atrial-fibrillation-if-advanced-echocardiography-plays-the-game
#5
Patrizio Lancellotti, Maurizio Galderisi
No abstract text is available yet for this article.
February 9, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29428185/lack-of-correlation-between-left-ventricular-outflow-tract-velocity-time-integral-and-stroke-volume-index-in-mechanically-ventilated-patients
#6
R Blancas, Ó Martínez-González, D Ballesteros, A Núñez, J Luján, D Rodríguez-Serrano, A Hernández, C Martínez-Díaz, C M Parra, B L Matamala, M A Alonso, M Chana
OBJECTIVE: To assess the correlation between left ventricular outflow tract velocity time integral (LVOT VTI) and stroke volume index (SVI) calculated by thermodilution methods in ventilated critically ill patients. DESIGN: A prospective, descriptive, multicenter study was performed. SETTING: Five intensive care units from university hospitals. PATIENTS: Patients older than 17 years needing mechanical ventilation and invasive hemodynamic monitoring were included...
February 7, 2018: Medicina Intensiva
https://www.readbyqxmd.com/read/29426678/low-yield-of-extensive-workup-for-embolic-sources-in-lacunar-stroke-patients
#7
Yan Wang, Yoon Choi, Joshuae Gallardo, Ifeoma Nwaneri, James R Brorson
OBJECTIVE: We aimed to evaluate the yield of extensive etiologic workup in lacunar stroke patients. BACKGROUND: As lacunar strokes are infrequently caused by thromboembolism, the clinical relevance of extensive workup for thromboembolic sources is questioned. METHODS: Among consecutive stroke admissions to a single center over 3 years, the 100 cases initially classified as lacunar stroke and a sample of 100 cases classified as non-lacunar ischemic strokes were studied...
February 6, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29426648/utility-of-left-atrial-expansion-index-and-stroke-volume-in-management-of-chronic-systolic-heart-failure
#8
Shih-Hung Hsiao, Shih-Kai Lin, Yi-Ran Chiou, Chin-Chang Cheng, Hwong-Ru Hwang, Kuan-Rau Chiou
BACKGROUND: Titration of evidence-based medications, important for treating heart failure (HF), is often underdosed by symptom-guided treatment. The aim of this study was to investigate, using echocardiographic parameters, stroke volume and left ventricular (LV) filling pressure to guide up-titration of medications, increasing prognostic benefits. METHODS: A total of 765 patients with chronic HF and severely reduced LV ejection fractions (<35%), referred from 2008 to 2016, were prospectively studied...
February 6, 2018: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29421006/mechanism-for-temporal-changes-in-exercise-capacity-after-fontan-palliation-role-of-doppler-echocardiography
#9
Alexander Egbe, Arooj R Khan, William R Miranda, Naser M Ammash, Carole A Warnes, Sameh S Said, Nathaniel W Taggart, Emmanuel Akintoye, Gruschen R Veldtman, Heidi M Connolly
BACKGROUND: The objective was to better understand Doppler hemodynamics and exercise capacity in patients with Fontan palliation by delineating the hemodynamic mechanism for temporal changes in their peak oxygen consumption (V̇o2). METHODS: We performed a retrospective review of adult Fontan patients with systemic left ventricle (LV) who underwent serial transthoracic echocardiograms (TTE) and cardiopulmonary exercise tests (CPET) at Mayo Clinic in 2000-2015. TTE and CPET data were used (1) to determine agreement between V̇o2 and Doppler-derived LV function indices (eg, stroke volume index [SVI] and cardiac index [CI]) and (2) to determine agreement between temporal changes in peak V̇o2 and LV function indices...
February 2018: American Heart Journal
https://www.readbyqxmd.com/read/29417743/cardiac-adaptation-to-hypertension-in-adult-female-dahl-salt-sensitive-rats-is-dependent-on-ovarian-function-but-loss-of-ovarian-function-does-not-predict-early-maladaptation
#10
Stian Ludvigsen, Costantino Mancusi, Simon Kildal, Giovanni de Simone, Eva Gerdts, Kirsti Ytrehus
Aim of study was to examine experimentally the adult female hypertensive heart in order to determine the role of ovary function in the response of the heart to salt-dependent hypertension. Dahl salt-sensitive rats, age 12 weeks, with/without ovariectomy were fed a standard (0.3% NaCl) or high-salt diet (8%) for 16 weeks. Mean arterial blood pressure monitored noninvasively in conscious state increased significantly by high salt. Echocardiography was performed at baseline and endpoint. Heart function and molecular changes were evaluated at endpoint by left ventricle catheterization, by sirius red staining for collagen and by gene expression using quantitative RT-PCR for selected genes...
February 2018: Physiological Reports
https://www.readbyqxmd.com/read/29415203/left-atrial-appendage-patency-and-device-related-thrombus-after-percutaneous-left-atrial-appendage-occlusion-a-computed-tomography-study
#11
Hubert Cochet, Xavier Iriart, Soumaya Sridi, Claudia Camaioni, Olivier Corneloup, Michel Montaudon, François Laurent, Wieme Selmi, Pauline Renou, Zakaria Jalal, Jean-Benoît Thambo
Aims: Transoesophageal echocardiography studies have reported frequent peri-device leaks and device-related thrombi (DRT) after percutaneous left atrial appendage (LAA) occlusion. We assessed the prevalence, characteristics and correlates of leaks and DRT on cardiac computed tomography (CT) after LAA occlusion. Methods and results: Consecutive patients underwent cardiac CT before LAA occlusion to assess left atrial (LA) volume, LAA shape, and landing zone diameter...
February 2, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29413646/assessment-of-left-ventricular-function-by-echocardiography-the-case-for-routinely-adding-global-longitudinal-strain-to-ejection-fraction
#12
REVIEW
Elizabeth Potter, Thomas H Marwick
Left ventricular (LV) ejection fraction (LVEF) is a simple measure of global systolic function that pervades the risk evaluation and management of many cardiovascular diseases. However, this parameter is limited not only by technical challenges, but also by pathophysiological entities where the ratio of stroke volume to LV cavity size is preserved. The assessment of global longitudinal strain (GLS) from speckle-tracking analysis of 2-dimensional echocardiography has become a clinically feasible alternative to LVEF for the measurement of myocardial function...
February 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29402843/sensitive-detection-of-atrial-fibrillation-in-acute-stroke-patients-by-short-term-bedside-electrocardiography-monitoring-software-analysis
#13
Linda Sarah Ross, Markus Bettin, Simon Kochhäuser, Martin Ritter, Jens Minnerup, Lars Eckardt, Florian Reinke, Ralf Dittrich
BACKGROUND: Atrial fibrillation (AF) is an important cause of stroke. Continuous electrocardiography (ECG) monitoring with software-based analysis algorithms has been suggested to enhance the AF detection rate. We investigated the ability of stroke risk analysis (SRA) in the detection of AF in acute stroke patients. METHODS: Consecutive stroke patients numbering 1,153 were screened. Patients with cardioembolic stroke related to AF (n = 296, paroxysmal n = 63, persistent n = 233) and patients with cryptogenic stroke (n = 309) after standard diagnostic work-up (bedside ECG monitoring, ultrasound, transesophageal echocardiography, 24 h Holter ECG) received SRA during their stay at the Stroke Unit...
January 17, 2018: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/29402710/safety-and-utility-of-dobutamine-and-pressure-wire-use-in-the-hemodynamic-assessment-of-low-flow-low-gradient-aortic-stenosis-with-reduced-left-ventricular-ejection-fraction
#14
Zaher Fanari, Prasad C Gunasekaran, Arslan Shaukat, Sumaya Hammami, Buddhadeb Dawn, Mark Wiley, Peter Tadros
BACKGROUND: The ACC/AHA guidelines recommend low-dose dobutamine challenge for hemodynamic assessment of the severity of AS in patients with low flow, low gradient aortic stenosis with reduced ejection fraction (EF) (LFLG-AS; stage D2). Inherent pitfalls of echocardiography could result in inaccurate aortic valve areas (AVA), which have downstream prognostic implications. Data on the safety and efficacy of coronary pressure wire and fluid-filled catheter use for low dose dobutamine infusion is sparse...
October 5, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29400653/short-term-dual-antiplatelet-therapy-after-interventional-left-atrial-appendage-closure-with-different-devices
#15
Felix K Weise, Stefano Bordignon, Laura Perrotta, Athanasios Konstantinou, Fabrizio Bologna, Takahiko Nagase, Shaojie Chen, K R Julian Chun, Boris Schmidt
AIMS: We aimed to assess the feasibility, efficacy and safety of short-term dual antiplatelet therapy (DAPT) for 6 weeks after left atrial appendage closure (LAAC). METHODS AND RESULTS: Data of the Cardioangiologisches Centrum Bethanien-LAAC registry were analysed. DAPT (aspirin 100mg plus clopidogrel 75mg) was administered until transoesophageal echocardiography (TEE) evaluation 6 weeks after LAAC. In the absence of significant peri-device flow or device-related thrombus (DRT) the medication was decreased to single antiplatelet therapy (SAPT)...
February 6, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29398195/does-epiaortic-ultrasound-screening-reduce-perioperative-stroke-in-patients-undergoing-coronary-surgery-a-topical-review
#16
REVIEW
Asad Ikram, Hafsa Mohiuddin, Aisha Zia, Hafiz Umair Siddiqui, Hoda Javadikasgari, Marijan Koprivanac, Sajjad Raza, Atif Zafar
Although the occurrence of stroke in patients undergoing coronary artery bypass grafting (CABG) is decreasing, it remains an important concern. Therefore, it is important to identify and adopt strategies that can decrease the incidence of stroke in these patients. One of the strategies that have demonstrated the potential to decrease the rate of post-CABG stroke is an assessment of aorta for atherosclerosis before surgery and changing the surgical plan accordingly to minimize the stroke risk. This assessment can be done through palpation of the aorta, transesophageal echocardiography (TEE), and epiaortic ultrasound scanning (EAS)...
February 2, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29395765/emergency-medicine-considerations-in-atrial-fibrillation
#17
REVIEW
Brit Long, Jennifer Robertson, Alex Koyfman, Kurian Maliel, Justin R Warix
BACKGROUND: Atrial fibrillation (AF) is an abnormal heart rhythm which may lead to stroke, heart failure, and death. Emergency physicians play a role in diagnosing AF, managing symptoms, and lessening complications from this dysrhythmia. OBJECTIVE: This review evaluates recent literature and addresses ED considerations in the management of AF. DISCUSSION: Emergency physicians should first assess patient clinical stability and evaluate and treat reversible causes...
January 30, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29395705/assessment-and-management-of-the-left-atrial-appendage-thrombus-in-patients-with-nonvalvular-atrial-fibrillation
#18
REVIEW
Yang Zhan, Jacqueline Joza, Mohamed Al Rawahi, Rodrigo S Barbosa, Michelle Samuel, Martin Bernier, Thao Huynh, George Thanassoulis, Vidal Essebag
BACKGROUND: Intracardiac thrombi arising in the left atrial appendage (LAA) are the principal cause of stroke in nonvalvular atrial fibrillation (AF). Predicting the presence of LAA thrombi is of vital importance in stratifying patients that would need further LAA imaging prior to cardioversion or AF ablation. METHODS: We comprehensively searched PubMed from its inception to November 2017 for randomized controlled trials, cohort and case control studies, as well as for case series on LAA thrombi risk factors, imaging, prevention, and anticoagulation management in atrial fibrillation...
December 15, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29395002/resolving-apparent-inconsistencies-between-area-flow-and-gradient-measurements-in-patients-with-aortic-valve-stenosis-and-preserved-left-ventricular-ejection-fraction
#19
Yujing Mo, Martin Penicka, Giuseppe Di Gioia, Emanuele Barbato, Tomas Ondrus, Marc Vanderheyden, Bernard De Bruyne, Jozef Bartunek, Guy Van Camp
Inconsistencies between area (aortic valve area [AVA])-flow-gradient are common during the echocardiographic assessment of aortic stenosis (AS). This study was conducted to investigate the importance of these inconsistencies and the impact of 3 methods to resolve these inconsistencies. The study population consisted of 327 patients (age: 76.3 ± 8.6 years, 49.5% males) with severe AS (SAS) (AVA ≤ 1 cm2) and preserved left ventricular ejection fraction (≥50%). Inconsistent findings between AVA, flow, and mean gradient (MG) were observed in 78 (23...
December 25, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29389808/cross-modality-accuracy-of-dual-step-prospectively-electrocardiography-triggered-dual-source-computed-tomorgaphy-compared-with-same-day-echocardiography-and-cardiac-magnetic-resonance-imaging-in-the-follow-up-of-heart-transplant-patients
#20
Riccardo Marano, Biagio Merlino, Luigi Natale, Giancarlo Savino, Vincenzo Vingiani, Giuseppe Rovere, Anna Rita Larici, Roberto Iezzi, Nicola Magarelli, Antonella Lombardo, Massimo Pasquale, Riccardo Manfredi
PURPOSE: An accurate evaluation of left ventricular volumes, mass, and ejection fraction (EF) and an early exclusion or detection of significant coronary artery disease or cardiac allograft vasculopathy are mandatory for clinical management and prognosis assessment of heart-transplanted patients (HTP). The purpose of this article was to evaluate the role of dual-step prospective electrocardiography-triggered Dual-Source CT (pECGdual-step-DSCT) in HTP for the assessment of left-ventricular function, in comparison with echocardiography (echo) and cardiac magnetic resonance (CMR) performed on the same day, and of the coronary arteries as well...
January 31, 2018: Journal of Thoracic Imaging
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