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https://www.readbyqxmd.com/read/28087076/polarization-of-microglia-and-its-role-in-bacterial-sepsis
#1
REVIEW
Monique Michels, Beatriz Sonai, Felipe Dal-Pizzol
Microglial polarization in response to brain inflammatory conditions is a crescent field in neuroscience. However, the effect of systemic inflammation, and specifically sepsis, is a relatively unexplored field that has great interest and relevance. Sepsis has been associated with both early and late harmful events of the central nervous system, suggesting that there is a close link between sepsis and neuroinflammation. During sepsis evolution it is supposed that microglial could exert both neurotoxic and repairing effects depending on the specific microglial phenotype assumed...
January 3, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/28086889/hybrid-brain-computer-interface-for-biomedical-cyber-physical-system-application-using-wireless-embedded-eeg-systems
#2
Rifai Chai, Ganesh R Naik, Sai Ho Ling, Hung T Nguyen
BACKGROUND: One of the key challenges of the biomedical cyber-physical system is to combine cognitive neuroscience with the integration of physical systems to assist people with disabilities. Electroencephalography (EEG) has been explored as a non-invasive method of providing assistive technology by using brain electrical signals. METHODS: This paper presents a unique prototype of a hybrid brain computer interface (BCI) which senses a combination classification of mental task, steady state visual evoked potential (SSVEP) and eyes closed detection using only two EEG channels...
January 7, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28081561/a-novel-richardson-lucy-model-with-dictionary-basis-and-spatial-regularization-for-isolating-isotropic-signals
#3
Tiantian Xu, Yuanjing Feng, Ye Wu, Qingrun Zeng, Jun Zhang, Jianzhong He, Qichuan Zhuge
Diffusion-weighted magnetic resonance imaging is a non-invasive imaging method that has been increasingly used in neuroscience imaging over the last decade. Partial volume effects (PVEs) exist in sampling signal for many physical and actual reasons, which lead to inaccurate fiber imaging. We overcome the influence of PVEs by separating isotropic signal from diffusion-weighted signal, which can provide more accurate estimation of fiber orientations. In this work, we use a novel response function (RF) and the correspondent fiber orientation distribution function (fODF) to construct different signal models, in which case the fODF is represented using dictionary basis function...
2017: PloS One
https://www.readbyqxmd.com/read/28081519/interoception-and-psychopathology-a-developmental-neuroscience-perspective
#4
REVIEW
Jennifer Murphy, Rebecca Brewer, Caroline Catmur, Geoffrey Bird
Interoception refers to the perception of the physiological condition of the body, including hunger, temperature, and heart rate. There is a growing appreciation that interoception is integral to higher-order cognition. Indeed, existing research indicates an association between low interoceptive sensitivity and alexithymia (a difficulty identifying one's own emotion), underscoring the link between bodily and emotional awareness. Despite this appreciation, the developmental trajectory of interoception across the lifespan remains under-researched, with clear gaps in our understanding...
December 23, 2016: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28081148/characterization-of-multi-drug-resistant-enterococcus-faecalis-isolated-from-cephalic-recording-chambers-in-research-macaques-macaca-spp
#5
Stephanie E Woods, Mia T Lieberman, Francois Lebreton, Elise Trowel, César de la Fuente-Núñez, Joanne Dzink-Fox, Michael S Gilmore, James G Fox
Nonhuman primates are commonly used for cognitive neuroscience research and often surgically implanted with cephalic recording chambers for electrophysiological recording. Aerobic bacterial cultures from 25 macaques identified 72 bacterial isolates, including 15 Enterococcus faecalis isolates. The E. faecalis isolates displayed multi-drug resistant phenotypes, with resistance to ciprofloxacin, enrofloxacin, trimethoprim-sulfamethoxazole, tetracycline, chloramphenicol, bacitracin, and erythromycin, as well as high-level aminoglycoside resistance...
2017: PloS One
https://www.readbyqxmd.com/read/28081141/could-a-neuroscientist-understand-a-microprocessor
#6
Eric Jonas, Konrad Paul Kording
There is a popular belief in neuroscience that we are primarily data limited, and that producing large, multimodal, and complex datasets will, with the help of advanced data analysis algorithms, lead to fundamental insights into the way the brain processes information. These datasets do not yet exist, and if they did we would have no way of evaluating whether or not the algorithmically-generated insights were sufficient or even correct. To address this, here we take a classical microprocessor as a model organism, and use our ability to perform arbitrary experiments on it to see if popular data analysis methods from neuroscience can elucidate the way it processes information...
January 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28080966/active-interoceptive-inference-and-the-emotional-brain
#7
REVIEW
Anil K Seth, Karl J Friston
We review a recent shift in conceptions of interoception and its relationship to hierarchical inference in the brain. The notion of interoceptive inference means that bodily states are regulated by autonomic reflexes that are enslaved by descending predictions from deep generative models of our internal and external milieu. This re-conceptualization illuminates several issues in cognitive and clinical neuroscience with implications for experiences of selfhood and emotion. We first contextualize interoception in terms of active (Bayesian) inference in the brain, highlighting its enactivist (embodied) aspects...
November 19, 2016: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28080961/interoception-beyond-homeostasis-affect-cognition-and-mental-health
#8
Manos Tsakiris, Hugo Critchley
Interoception refers to the sensing of the internal state of one's body. Interoception is distinct from the processing of sensory information concerning external (non-self) stimuli (e.g. vision, hearing, touch and smell) and is the afferent axis to internal (autonomic and hormonal) physiological control. However, the impact of interoception extends beyond homeostatic/allostatic reflexes: it is proposed to be fundamental to motivation, emotion (affective feelings and behaviours), social cognition and self-awareness...
November 19, 2016: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28079736/report-on-neurosciences-sessions-during-the-16th-world-congress-of-anaesthesiologists-wca-2016-hong-kong
#9
Gyaninder P Singh, Girija P Rath
No abstract text is available yet for this article.
January 10, 2017: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/28079187/a-spiking-neural-network-model-of-3d-perception-for-event-based-neuromorphic-stereo-vision-systems
#10
Marc Osswald, Sio-Hoi Ieng, Ryad Benosman, Giacomo Indiveri
Stereo vision is an important feature that enables machine vision systems to perceive their environment in 3D. While machine vision has spawned a variety of software algorithms to solve the stereo-correspondence problem, their implementation and integration in small, fast, and efficient hardware vision systems remains a difficult challenge. Recent advances made in neuromorphic engineering offer a possible solution to this problem, with the use of a new class of event-based vision sensors and neural processing devices inspired by the organizing principles of the brain...
January 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28079083/neuroscience-the-risks-of-reading-the-brain
#11
Russell Poldrack
No abstract text is available yet for this article.
January 11, 2017: Nature
https://www.readbyqxmd.com/read/28079076/neuroscience-age-sees-boost-in-facial-recognition
#12
(no author information available yet)
No abstract text is available yet for this article.
January 11, 2017: Nature
https://www.readbyqxmd.com/read/28078990/mass-spectrometry-imaging-in-nanomedicine-unraveling-the-potential-of-msi-for-the-detection-of-nanoparticles-in-neuroscience
#13
Florian Py Barré, Ron Ma Heeren, Nina Ogrinc Potočnik
Mass spectrometry imaging (MSI) can uniquely detect thousands of compounds allowing both their identification and localization within biological tissue samples. MSI is an interdisciplinary science that crosses the borders of physics, chemistry and biology, and enables local molecular analysis at a broad range of length scales: From the subcellular level to whole body tissue sections. The spatial resolution of some mass spectrometers now allows nano-scale research, crucial for studies in nanomedicine. Recent developments in MSI have enabled the optimization and localization of drug delivery with nanoparticles within the body and in specific organs such as kidney, liver and brain...
January 11, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28077259/the-growth-of-language-universal-grammar-experience-and-principles-of-computation
#14
REVIEW
Charles Yang, Stephen Crain, Robert C Berwick, Noam Chomsky, Johan J Bolhuis
YANG, C., S. Crain, R.C. Berwick, N. Chomsky and J.J. Bolhuis. The growth of language. NEUROSCI BIOBEHAV REV VOL (ISSUE) XXX-XXX, 2016. Human infants develop language remarkably rapidly and without overt instruction. We argue that the distinctive ontogenesis of child language arises from the interplay of three factors: domain-specific principles of language (Universal Grammar), external experience, and properties of non-linguistic domains of cognition including general learning mechanisms and principles of efficient computation...
January 7, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28077003/influence-of-extrinsic-inputs-and-synaptic-gains-on-dynamics-of-wendling-s-neural-mass-model-a-bifurcation-analysis
#15
Shujuan Geng, Weidong Zhou
We analyze the neurodynamics attributed by a model proposed by Wendling and co-workers (2002) [Wendling, F., Bartolomei, F., Bellanger, J.J. & Chauvel, P. (2002) Epileptic fast activity can be explained by a model of impaired GABAergic dendritic inhibition. Eur. J. Neurosci., 15, 1499.] to explain several different types of electroencephalographic activities. We could find three principal types of steady states when the system parameters change slowly: (i) the model produce a constant output when it is under a state of stable equilibrium point with a constant input...
January 11, 2017: Journal of Integrative Neuroscience
https://www.readbyqxmd.com/read/28076353/a-topological-criterion-for-filtering-information-in-complex-brain-networks
#16
Fabrizio De Vico Fallani, Vito Latora, Mario Chavez
In many biological systems, the network of interactions between the elements can only be inferred from experimental measurements. In neuroscience, non-invasive imaging tools are extensively used to derive either structural or functional brain networks in-vivo. As a result of the inference process, we obtain a matrix of values corresponding to a fully connected and weighted network. To turn this into a useful sparse network, thresholding is typically adopted to cancel a percentage of the weakest connections...
January 11, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28074926/disrupted-global-metastability-and-static-and-dynamic-brain-connectivity-across-individuals-in-the-alzheimer-s-disease-continuum
#17
Aldo Córdova-Palomera, Tobias Kaufmann, Karin Persson, Dag Alnæs, Nhat Trung Doan, Torgeir Moberget, Martina Jonette Lund, Maria Lage Barca, Andreas Engvig, Anne Brækhus, Knut Engedal, Ole A Andreassen, Geir Selbæk, Lars T Westlye
As findings on the neuropathological and behavioral components of Alzheimer's disease (AD) continue to accrue, converging evidence suggests that macroscale brain functional disruptions may mediate their association. Recent developments on theoretical neuroscience indicate that instantaneous patterns of brain connectivity and metastability may be a key mechanism in neural communication underlying cognitive performance. However, the potential significance of these patterns across the AD spectrum remains virtually unexplored...
January 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28074777/cell-assemblies-at-multiple-time-scales-with-arbitrary-lag-constellations
#18
Eleonora Russo, Daniel Durstewitz
Hebb's idea of a cell assembly as the fundamental unit of neural information processing has dominated neuroscience like no other theoretical concept within the past 60 years. A range of different physiological phenomena, from precisely synchronized spiking to broadly simultaneous rate increases, has been subsumed under this term. Yet progress in this area is hampered by the lack of statistical tools that would enable to extract assemblies with arbitrary constellations of time lags, and at multiple temporal scales, partly due to the severe computational burden...
January 11, 2017: ELife
https://www.readbyqxmd.com/read/28074755/attachment-theory-and-neuroscience-for-care-managers
#19
Thomas J Blakely, Gregory M Dziadosz
This article describes a model for care managers that is based on attachment theory supplemented by knowledge from neuroscience. Together, attachment theory and basic knowledge from neuroscience provide for both an organizing conceptual framework and a scientific, measureable approach to assessment and planning interventions in a care plan.
September 1, 2016: Care Management Journals: Journal of Case Management ; the Journal of Long Term Home Health Care
https://www.readbyqxmd.com/read/28074581/conflating-capacity-authority-why-we-re-asking-the-wrong-question-in-the-adolescent-decision-making-debate
#20
Erica K Salter
Whether adolescents should be allowed to make their own medical decisions has been a topic of discussion in bioethics for at least two decades now. Are adolescents sufficiently capacitated to make their own medical decisions? Is the mature-minor doctrine, an uncommon legal exception to the rule of parental decision-making authority, something we should expand or eliminate? Bioethicists have dealt with the curious liminality of adolescents-their being neither children nor adults-in a variety of ways. However, recently there has been a trend to rely heavily, and often exclusively, on emerging neuroscientific and psychological data to answer these questions...
January 2017: Hastings Center Report
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