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Omega 3 fatty acids

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https://www.readbyqxmd.com/read/27920494/presence-or-absence-of-ocular-surface-inflammation-directs-clinical-and-therapeutic-management-of-dry-eye
#1
Robert Sambursky
BACKGROUND: The presence of clinically significant inflammation has been confirmed in the tears of 40%-65% of patients with symptoms of dry eye. Ocular surface inflammation may lead to tear film instability, epithelial cell irregularities, and permeability, resulting in chronic symptomatic pain and fluctuating vision as well as negative surgical outcomes. PATIENTS AND METHODS: A retrospective single center medical chart review of 100 patients was conducted. All patients were tested with the InflammaDry test to determine if patients exhibited elevated levels of matrix metalloproteinase 9 (MMP-9)...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27919362/the-effect-of-omega-3-carboxylic-acids-on-apolipoprotein-ciii-containing-lipoproteins-in-severe-hypertriglyceridemia
#2
Allyson M Morton, Jeremy D Furtado, Jane Lee, William Amerine, Michael H Davidson, Frank M Sacks
BACKGROUND: Lipoprotein subspecies containing apoCIII adversely affect cardiovascular disease (CVD) risk; for example, low density lipoprotein (LDL) with apoCIII is a stronger CVD predictor than LDL without apoCIII. The Epanova for Lowering Very High Triglycerides (EVOLVE) trial showed that Epanova (omega-3 carboxylic acids [OM3-CA]) significantly lowered TG and apoCIII but raised LDL-C. However, it is unknown what subspecies of LDL were affected by treatment. OBJECTIVE: To determine how lipoprotein subspecies are affected by omega-3 fatty acid treatment, we studied the effect of OM3-CA on apoCIII concentrations in high density lipoprotein (HDL), LDL, and very low density lipoprotein (VLDL) and on the concentrations of subspecies of HDL, LDL, and VLDL that contain or do not contain apoCIII...
November 2016: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/27919272/enhanced-lipid-and-biomass-production-by-a-newly-isolated-and-identified-marine-microalga
#3
Mouna Dammak, Sandra Mareike Haase, Ramzi Miladi, Faten Ben Amor, Mohamed Barkallah, David Gosset, Chantal Pichon, Bernhard Huchzermeyer, Imen Fendri, Michel Denis, Slim Abdelkafi
BACKGROUND: The increasing demand for microalgae lipids as an alternative to fish has encouraged researchers to explore oleaginous microalgae for food uses. In this context, optimization of growth and lipid production by the marine oleaginous V2-strain-microalgae is of great interest as it contains large amounts of mono-unsaturated (MUFAs) and poly-unsaturated fatty acids (PUFAs). METHODS: In this study, the isolated V2 strain was identified based on 23S rRNA gene...
December 5, 2016: Lipids in Health and Disease
https://www.readbyqxmd.com/read/27916361/oral-omega-3-fatty-acids-promote-resolution-in-chemical-peritonitis
#4
Alexander C Chacon, Brett E Phillips, Miranda A Chacon, Deborah Brunke-Reese, Shannon L Kelleher, David I Soybel
BACKGROUND: Recent studies suggest that purified omega-3 fatty acids may attenuate acute inflammation and hasten the transition to healing. In this study, we tested the hypothesis that pretreatment with omega-3-rich fish oil (FO) would promote resolution of peritoneal inflammation through production of specific lipid mediators. METHODS: C57/BL6 mice were given a daily 200-μL oral gavage of saline (CTL) or FO (1.0-1.5 g/kg/d docosahexaenoic acid and 1.3-2.0 g/kg/d eicosapentaenoic acid) for 7 d before chemical peritonitis was induced with thioglycollate...
November 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27914517/effect-of-flaxseed-oil-and-microalgae-dha-on-the-production-performance-fatty-acids-and-total-lipids-of-egg-yolk-and-plasma-in-laying-hens
#5
M Neijat, O Ojekudo, J D House
The incorporation of omega-3 polyunsaturated fatty acids (PUFA) in the egg is dependent on both the transfer efficiency of preformed dietary omega-3 fatty acids to the eggs as well as endogenous PUFA metabolism and deposition. Employing an experimental design consisting of 70 Lohmann LSL-Classic hens (n=10/treatment) in a 6-week feeding trial, we examined the impact of graded levels of either flaxseed oil (alpha-linolenic acid, ALA) or algal DHA (preformed docosahexaenoic acid, DHA), each supplying 0.20%, 0...
December 2016: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/27913933/fatigue-reduction-diet-in-breast-cancer-survivors-a-pilot-randomized-clinical-trial
#6
Suzanna Maria Zick, Justin Colacino, Maria Cornellier, Tohfa Khabir, Katie Surnow, Zora Djuric
PURPOSE: Fatigue is a prevalent and burdensome effect of breast cancer. Fatigue has been linked to chronic inflammation, and diets high in antioxidant nutrients have been associated with lesser prevalence and severity of fatigue. Studies are needed, however, to test if antioxidant-rich diets could improve fatigue. METHODS: Pilot, randomized, trial conducted between January 2014 and April 2015, to investigate if a 3-month diet rich in fruit, vegetables, whole grains, and omega-3 fatty acid-rich foods, named the fatigue reduction diet (FRD), improved fatigue and sleep compared to an attention control, named the general health curriculum (GHC)...
December 2, 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27912872/anti-allergic-potential-of-typhonium-blumei-inhibition-of-degranulation-via-suppression-of-pi3k-plc%C3%AE-2-phosphorylation-and-calcium-influx
#7
Michal Korinek, Kuan-Ming Chen, Yu-Han Jiang, Mohamed El-Shazly, Joel Stocker, Chon-Kit Chou, Tsong-Long Hwang, Yang-Chang Wu, Bing-Hung Chen, Fang-Rong Chang
BACKGROUND: Typhonium blumei Nicolson & Sivadasan (Araceae) is a traditional Chinese medicinal herb possessing detumescent, detoxifying, and anti-inflammatory activities. It is used in Taiwan as a folk medicine to treat cancer and inflammatory diseases. Typhonium blumei is usually not distinguished from Typhonium roxburghii Schott and they are commonly used interchangeably. PURPOSE: To evaluate and compare the anti-allergic and anti-inflammatory properties of T...
December 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/27905863/associations-between-omega-3-fatty-acids-selenium-content-and-mercury-levels-in-wild-harvested-fish-from-the-dehcho-region-northwest-territories-canada
#8
Ellen S Reyes, Juan J Aristizabal Henao, Katherine M Kornobis, Rhona M Hanning, Shannon E Majowicz, Karsten Liber, Ken D Stark, George Low, Heidi K Swanson, Brian D Laird
To better understand the risks and benefits of eating wild-harvested fish from the Northwest Territories, Canada, levels of total mercury (HgT) and selenium (Se) and composition of omega-3 fatty acid (n-3 FA) were measured in muscle tissue of fish harvested from lakes in the Dehcho Region, Northwest Territories, Canada. Average HgT levels ranged from 0.057 mg/kg (cisco) to 0.551 mg/kg (northern pike), while average n-3 FA concentrations ranged from 101 mg/100 g (burbot) to 1,689 mg/100 g (lake trout). In contrast to HgT and n-3 FA, mean Se concentrations were relatively similar among species...
December 1, 2016: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/27903997/effects-of-omega-3-fatty-acid-supplementation-on-serum-biomarkers-inflammatory-agents-and-quality-of-life-of-patients-on-hemodialysis
#9
Firouzeh Moeinzadeh, Shahrzad Shahidi, Mojgan Mortazavi, Shahaboddin Dolatkhah, Mohammadhossein Kajbaf, Shaghayegh Haghjooy Javanmard, Alireza Moghtaderi
INTRODUCTION: Patients on long-term hemodialysis are at a higher risk of cardiovascular disease and premature mortality. It is generally believed that omega-3 supplementation can prevent cardiovascular events due to its anti-inflammatory and anti-atherosclerotic effects. MATERIALS AND METHODS: Fifty-two hemodialysis patients were divided into 2 groups to receive omega-3 and placebo for 6 six months. Serum biomarkers and inflammatory agents were measured in both groups before and after the intervention...
November 2016: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/27902774/intravenous-treatment-with-a-long-chain-omega-3-lipid-emulsion-provides-neuroprotection-in-a-murine-model-of-ischemic-stroke-a-pilot-study
#10
Dirk Berressem, Konrad Koch, Nicole Franke, Jochen Klein, Gunter P Eckert
Single long-chain omega-3 fatty acids (e.g. docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA)) are known for their neuroprotective properties associated with ischemic stroke. This pilot study aimed to test the effectiveness of an acute treatment with a long-chain omega-3 lipid emulsion (Omegaven 10%®, OGV) that contains fish oil (DHA 18 mg/ml; EPA 21 mg/ml) and α-tocopherol (0.2 mg/ml) in a transient middle cerebral artery occlusion (MCAO) model of ischemic stroke in mice. For this purpose, female CD-1 mice were anesthetized and subjected to 90 minutes of MCAO...
2016: PloS One
https://www.readbyqxmd.com/read/27902432/self-replicating-shuttle-vectors-based-on-pans-a-small-endogenous-plasmid-of-the-unicellular-cyanobacterium-synechococcus-elongatus-pcc-7942
#11
You Chen, Arnaud Taton, Michaela Go, Ross E London, Lindsey M Pieper, Susan S Golden, James W Golden
To facilitate development of synthetic biology tools for genetic engineering of cyanobacterial strains, we constructed pANS-derived self-replicating shuttle vectors that are based on the minimal replication element of the Synechococcus elongatus strain PCC 7942 plasmid pANS. To remove the possibility of homologous recombination events between the shuttle plasmids and the native pANS plasmid, the endogenous pANS was cured through plasmid incompatibility-mediated spontaneous loss. A heterologous toxin-antitoxin cassette was incorporated into the shuttle vectors for stable plasmid maintenance in the absence of antibiotic selection...
October 14, 2016: Microbiology
https://www.readbyqxmd.com/read/27900411/inflammatory-protein-response-in-cdkl5-rett-syndrome-evidence-of-a-subclinical-smouldering-inflammation
#12
Alessio Cortelazzo, Claudio de Felice, Silvia Leoncini, Cinzia Signorini, Roberto Guerranti, Roberto Leoncini, Alessandro Armini, Luca Bini, Lucia Ciccoli, Joussef Hayek
BACKGROUND: Mutations in the cyclin-dependent kinase-like 5 gene cause a clinical variant of Rett syndrome (CDKL5-RTT). A role for the acute-phase response (APR) is emerging in typical RTT caused by methyl-CpG-binding protein 2 gene mutations (MECP2-RTT). No information is, to date, available on the inflammatory protein response in CDKL5-RTT. We evaluated, for the first time, the APR protein response in CDKL5-RTT. METHODS: Protein patterns in albumin- and IgG-depleted plasma proteome from CDKL5-RTT patients were evaluated by two-dimensional gel electrophoresis/mass spectrometry...
November 29, 2016: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
https://www.readbyqxmd.com/read/27898904/feeding-microalgae-meal-all-g-rich-ccap-4087-2-to-beef-heifers-i-effects-on-longissimus-lumborum-steak-color-and-palatibility
#13
K J Phelps, J S Drouillard, T G O'Quinn, D D Burnett, T L Blackmon, J E Axman, C L Van Bibber-Krueger, J M Gonzalez
The objective of this study was to examine effects of 4 levels of microalgae meal (All-G Rich, CCAP 4087/2; Alltech Inc., Nicholasville, KY) supplementation to the diet of finishing heifers on longissimus lumborum (LL) steak PUFA content, beef palatability, and color stability. Crossbred heifers ( = 288; 452 ± 23 kg initial BW) were allocated to pens (36 pens and 8 heifers/pen), stratified by initial pen BW (3,612 ± 177 kg), and randomly assigned within strata to 1 of 4 treatments: 0, 50, 100, and 150 g·heifer·d of microalgae meal...
September 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27897391/a-systematic-review-on-the-role-of-vitamins-minerals-proteins-and-other-supplements-for-the-treatment-of-cachexia-in-cancer-a-european-palliative-care-research-centre-cachexia-project
#14
REVIEW
Mochamat, Henning Cuhls, Milka Marinova, Stein Kaasa, Christiane Stieber, Rupert Conrad, Lukas Radbruch, Martin Mücke
We provide a systematic review to support the European Palliative Care Research Collaboration development of clinical guidelines for cancer patients suffering from cachexia. CENTRAL, MEDLINE, PsycINFO, ClinicalTrials.gov, and a selection of cancer journals have been searched up until 15 April 2016. The systematic literature research yielded 4214 publications with 21 of these included in the final evaluation. Regarding minerals, our search identified only one study examining the use of magnesium with no effect on weight loss...
July 20, 2016: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/27894336/curcumin-and-long-chain-omega-3-polyunsaturated-fatty-acids-for-prevention-of-type-2-diabetes-cop-d-study-protocol-for-a-randomised-controlled-trial
#15
Rohith N Thota, Shamasunder H Acharya, Kylie A Abbott, Manohar L Garg
BACKGROUND: Lifestyle interventions, including increase in physical activity and dietary counselling, have shown the ability to prevent type 2 diabetes (T2D) in high-risk state individuals, but the prevalence is still skyrocketing in Australia, in line with global prevalence. Currently, no medicines are approved by the Therapeutic Goods Administration in Australia for the management of prediabetes. Therefore, there is a need of developing a safer, biologically efficacious and cost-effective alternative for delaying the transition of individual health state from prediabetes into T2D...
November 29, 2016: Trials
https://www.readbyqxmd.com/read/27889806/a-comparative-assessment-of-arsenic-risks-and-the-nutritional-benefits-of-fish-consumption-in-kuwait-arsenic-versus-omega-3-fatty-acids
#16
Adnan Husain, Kurunthachalam Kannan, Hing Man Chan, Brian Laird, Hanan Al-Amiri, Basma Dashti, Anwar Sultan, Amani Al-Othman, Bedraya Mandekar
Inorganic and organic forms of arsenic (As), as well as omega-3 fatty acids were measured in 578 fish/seafood samples that belong to 15 species of commonly consumed seafood in Kuwait. Arsenic speciation data, with the toxicological profile of inorganic arsenic (iAs) and fish consumption rates were applied in a probabilistic risk assessment to estimate the risk from exposure to iAs. The nutritional benefits of omega-3-fatty acid levels in various species of fish were taken into consideration. Results showed that the mean daily intake of iAs through fish consumption among the Kuwaiti population was 0...
November 26, 2016: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/27888762/nutritional-preconditioning-by-marine-omega-3-fatty-acids-in-patients-with-st-segment-elevation-myocardial-infarction-a-metocard-cnic-trial-substudy
#17
Aleix Sala-Vila, Rodrigo Fernández-Jiménez, Gonzalo Pizarro, Carlos Calvo, Jose M García-Ruiz, Leticia Fernández-Friera, Maite D Rodriguez, Noemí Escalera, Jorge Palazuelos, Angel Macías, Braulio Pérez-Asenjo, Antonio Fernández-Ortiz, Emilio Ros, Valentín Fuster, Borja Ibáñez
No abstract text is available yet for this article.
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27884389/omega-3-fatty-acids-for-the-treatment-of-dementia
#18
Patrick Phillips
No abstract text is available yet for this article.
September 14, 2016: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/27883909/anti-inflammatory-effect-of-a-fatty-acid-mixture-with-high-%C3%AF-9-%C3%AF-6-ratio-and-low-%C3%AF-6-%C3%AF-3-ratio-on-rats-submitted-to-dental-extraction
#19
Radamés Bezerra Melo, Paulo Goberlânio de Barros Silva, Reinaldo Barreto Oriá, José Ulisses de Souza Melo, Conceição da Silva Martins, Aline Matos Cunha, Paulo Roberto Leitão Vasconcelos
OBJECTIVE: To evaluate the anti-inflammatory effect of pretreatment for three days with a fatty acid mixture with high ω-9:ω-6 ratio and low ω-6:ω-3 ratio on rats submitted to dental extraction. MATERIAL AND METHODS: Thirty-two male Wistar rats (270-310g) were randomly distributed in four groups (n=8/group): the sham control group and the negative control group received saline; the high omega-6/low omega-9 group received isolipid fatty acid with high ω-6:ω-3 ratio and low ω-9:ω-6 ratio; the high omega-3/low omega-6 group received fatty acid with low ω-6:ω-3 ratio and high ω-9:ω-6 ratio...
November 16, 2016: Archives of Oral Biology
https://www.readbyqxmd.com/read/27883274/impact-of-the-chronic-omega-3-fatty-acids-supplementation-in-hemiparkinsonism-model-induced-by-6-hydroxydopamine-in-rats
#20
Alexandre Sales Barros, Rafael Yuri Gouveia Crispim, Juliana Cavalcante Uchoa, Ricardo Basto Souza, Jonatas Cavalcante Lemos, Gerardo Cristino Filho, Mirna Marques Bezerra, Thales Fontenele Moraes Pinheiro, Silvânia Maria Mendes de Vasconcelos, Danielle Silveira Macêdo, Glauce Socorro de Barros Viana, Lissiana Magna Vasconcelos Aguiar
Parkinson's disease (PD) is characterized by a progressive degeneration of dopaminergic neurons in the substantia nigra. The neuronal degeneration may result from the convergence of a number of different pathogenic factors, including apoptosis, excitotoxicity and oxidative stress. Many studies emphasize the importance of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) in vital processes such as maintenance of the properties of cell membranes and the participation in signal transduction and biodynamic activity of neuronal membranes...
November 24, 2016: Basic & Clinical Pharmacology & Toxicology
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