keyword
MENU ▼
Read by QxMD icon Read
search

Hypochlorite

keyword
https://www.readbyqxmd.com/read/28338335/stress-induced-protein-s-glutathionylation-and-s-trypanothionylation-in-african-trypanosomes-a-quantitative-redox-proteome-and-thiol-analysis
#1
Kathrin Ulrich, Caroline Finkenzeller, Sabine Merker, Federico Rojas, Keith Matthews, Thomas Ruppert, R Luise Krauth-Siegel
AIMS: Trypanosomatids have a unique trypanothione-based thiol redox metabolism. The parasite-specific dithiol is synthesized from glutathione and spermidine, with glutathionylspermidine as intermediate catalyzed by trypanothione synthetase. In this study, we address the oxidative stress response of African trypanosomes with special focus on putative protein S-thiolation. RESULTS: Challenging bloodstream Trypanosoma brucei with diamide, H2O2 or hypochlorite results in distinct levels of reversible overall protein S-thiolation...
March 24, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28325624/clinical-outcomes-for-primary-molars-treated-by-different-types-of-pulpotomy-a%C3%A2-retrospective-cohort-study
#2
Heng-Yeh Kuo, Jr-Rung Lin, Wen-Hsi Huang, Meng-Ling Chiang
BACKGROUND/PURPOSE: Pulpotomy is the amputation of coronally infected pulp tissue to maintain the vitality and function of the radicular pulp. This study was designed to assess the clinical and radiographic success rates of primary molars treated by pulpotomy using diode laser, sodium hypochlorite, or no medication after a follow-up period of 24 months. METHODS: A retrospective study was conducted by evaluating the success rates of primary molars treated by pulpotomy with diode laser, sodium hypochlorite, or no medication according to the clinical symptoms and signs and radiographic features...
March 18, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28322835/role-of-mitochondrial-dysfunction-in-renal-fibrosis-promoted-by-hypochlorite-modified-albumin-in-a-remnant-kidney-model-and-protective-effects-of-antioxidant-peptide-ss-31
#3
Hao Zhao, Yan-Jun Liu, Zong-Rui Liu, Dong-Dong Tang, Xiao-Wen Chen, Yi-Hua Chen, Ru-Ning Zhou, Si-Qi Chen, Hong-Xin Niu
Oxidative stress aggravates renal fibrosis, a pathway involved in almost all forms of chronic kidney disease (CKD). However, the underlying mechanism involved in the pathogenesis of renal oxidative stress has not been completely elucidated. In this study, we explored the role and mechanism of hypochlorite-modified albumin (HOCl-alb) in mediating oxidative stress and fibrotic response in a remnant-kidney rat model. Five-sixths nephrectomy (5/6 NX) was performed on the rats and then the animals were randomly assigned to intravenous treatment with either vehicle alone, or HOCl-rat serum albumin (RSA) in the presence or absence of SS-31 (administered intraperitoneally)...
March 18, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28318172/-accidental-injection-of-sodium-hypochlorite-in-inferior-alveolar-nerve-block-anesthesia
#4
Li Hongyan, Xu Jian, Zhang Baorong, Jia Yue, Liu Minhua, Luo Yilang, Zhao Jing
Sodium hypochlorite (NaClO) has been widely used in clinical practice as one of the most efficient root canal irrigants. Its properties include broad-spectrum antimicrobial activity and ability to dissolve necrotic tissues. However, when used improperly, NaClO can cause a series of adverse reactions, such as mucosal inflammation, irritation, or injury. This paper presents a case of accidental injection of NaClO in inferior alveolar nerve block anesthesia.
December 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28306162/analysis-of-the-effects-of-several-decalcifying-agents-alone-and-in-combination-with-sodium-hypochlorite-on-the-chemical-composition-of-dentine
#5
T Tartari, L Bachmann, R F Zancan, R R Vivan, M A H Duarte, C M Bramante
AIM: To investigate the effects of several decalcifying agents alone and in combination with sodium hypochlorite (NaOCl) on the organic and inorganic components of dentine using Attenuated Total Reflectance in Fourier Transform Infrared Spectroscopy (ATR-FTIR). METHODOLOGY: Dentine slices from bovine teeth were submitted to (n=5): 0.9% saline, 9% and 18% etidronic acid (HEDP), 5% and 10% tetrasodium EDTA (EDTANa4 ), 17% trisodium EDTA (EDTAHNa3 ), and 0.5% and 2...
March 17, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28302859/inflammation-boosts-bacteriophage-transfer-between-salmonella-spp
#6
Médéric Diard, Erik Bakkeren, Jeffrey K Cornuault, Kathrin Moor, Annika Hausmann, Mikael E Sellin, Claude Loverdo, Abram Aertsen, Martin Ackermann, Marianne De Paepe, Emma Slack, Wolf-Dietrich Hardt
Bacteriophage transfer (lysogenic conversion) promotes bacterial virulence evolution. There is limited understanding of the factors that determine lysogenic conversion dynamics within infected hosts. A murine Salmonella Typhimurium (STm) diarrhea model was used to study the transfer of SopEΦ, a prophage from STm SL1344, to STm ATCC14028S. Gut inflammation and enteric disease triggered >55% lysogenic conversion of ATCC14028S within 3 days. Without inflammation, SopEΦ transfer was reduced by up to 10(5)-fold...
March 17, 2017: Science
https://www.readbyqxmd.com/read/28301954/the-role-of-bacillithiol-in-gram-positive-firmicutes
#7
Pete Chandrangsu, Vu Van Loi, Haike Antelmann, John D Helmann
SIGNIFICANCE: Since the discovery and structural characterization of bacillithiol (BSH), the biochemical functions of BSH-biosynthesis enzymes (BshA/B/C) and BSH-dependent detoxification enzymes (FosB, Bst, GlxA/B) have been explored in Bacillus and Staphylococcus species. It was shown that BSH plays an important role in detoxification of reactive oxygen and electrophilic species, alkylating agents, toxins and antibiotics. Recent Advances: More recently, new functions of BSH were discovered in metal homeostasis (Zn buffering, FeS-cluster and copper homeostasis) and virulence control in Staphylococcus aureus...
March 16, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28301017/intracanal-irrigating-solutions-prior-to-calcium-hydroxide-medication-and-its-effects-on-root-dentin-strength
#8
Leila Clarisse Hillesheim, Juliara Bellina Hoffmann, Daniela Peressoni Vieira Schuldt, Maybell Tedesco, Eduardo Antunes Bortoluzzi, Cleonice Silveira Teixeira
The aim of this study was to assess the effects of intracanal irrigation with sodium hypochlorite (NaOCl) and ethylenediaminetetracetic acid (EDTA) prior to calcium hydroxide medication on the compressive strength of root dentin. Forty-eight roots with single and straight canals were instrumented with a crown-down technique using Flexofile files and Gates Glidden burs, under 0.9% sodium chloride (NaCl) irrigation. Root canals were randomly separated into 4 groups (n=12), according to the irrigating solution: Control Group, 0...
January 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/28298975/evaluation-of-antimicrobial-and-antifungal-efficacy-of-chitosan-as-endodontic-irrigant-against-enterococcus-faecalis-and-candida-albicans-biofilm-formed-on-tooth-substrate
#9
Pankaj Yadav, Sarika Chaudhary, Rajendra K Saxena, Sangeeta Talwar, Sudha Yadav
BACKGROUND: Bacterial biofilms formed on the root canal wall are often difficult to remove. This study aimed to evaluate the cytotoxic effect and antibacterial efficacy of chitosan when used as root canal irrigant against E. Faecalis and Candida albicans biofilm formed on tooth substrate. MATERIAL AND METHODS: The present study evaluated antibacterial effect of 0.25% Chitosan, 0.5% Chitosan, 2% chlorhexidine and 3% sodium hypochlorite against Enterococcus faecalis and Candida Albicans...
March 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28296388/degradable-semiconducting-oligomer-amphiphile-for-ratiometric-photoacoustic-imaging-of-hypochlorite
#10
Chao Yin, Xu Zhen, Quli Fan, Wei Huang, Kanyi Pu
Upregulation of highly reactive oxygen species (ROS) such as hypochlorite (ClO-) is associated with many pathological conditions including cardiovascular diseases, neuron degeneration, lung injury and cancer. However, real-time imaging of ClO- is limited to the probes generally relying on fluorescence with shallow tissue-penetration depth. We here propose a self-assembly approach to develop activatable and degradable photoacoustic (PA) nanoprobes for in vivo imaging of ClO-. A near-infrared (NIR) absorbing amphiphilic oligomer was synthesized to undergo degradation in the presence of a specific ROS (ClO-), which integrates a π-conjugated but ClO- oxidizable backbone with hydrophilic PEG side chains...
March 15, 2017: ACS Nano
https://www.readbyqxmd.com/read/28294602/surface-cleaning-and-disinfection-efficacy-assessment-of-four-chlorine-types-using-e-coli-and-the-ebola-surrogate-phi6
#11
Karin Gallandat, Marlene K Wolfe, Daniele S Lantagne
In the 2014 West African Ebola outbreak, international organizations provided conflicting recommendations for disinfecting surfaces contaminated by uncontrolled patient spills. We compared the efficacy of four chlorine solutions (sodium hypochlorite, sodium dichloroisocyanurate, high-test hypochlorite, and generated hypochlorite) for disinfection of three surface types (stainless steel, heavy duty tarp, and nitrile), with and without pre-cleaning practices (pre-wiping and/or covering) and soil load. The test organisms were E...
March 15, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28292337/primary-tooth-vital-pulp-therapy-a-systematic-review-and-meta-analysis
#12
James A Coll, N Sue Seale, Kaaren Vargas, Abdullah A Marghalani, Shahad Al Shamali, Laurel Graham
PURPOSE: This systematic review and meta-analysis assessed outcomes in primary teeth for the vital pulp therapy (VPT) options of indirect pulp therapy (IPT), direct pulp capping (DPC), and pulpotomy after a minimum of 12 months to determine whether one VPT was superior. METHODS: The following databases were searched from 1960 to September 2016: MEDLINE, EMBASE, CENTRAL, EBSCO, ICTRP, Dissertation abstracts, and grey literature for parallel and split-mouth randomized controlled trials of at least 12 months duration comparing the success of IPT, DPC, and pulpotomy in children with deep caries in primary teeth...
January 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/28290673/oxidations-at-sulfur-centers-by-aqueous-hypochlorous-acid-and-hypochlorite-cl-versus-o-atom-transfer
#13
Ying Hu, Guangyuan Xie, David M Stanbury
Sulfur-containing compounds are known to be susceptible to oxidation by aqueous HOCl, but the factors affecting the rates of these reactions are not well-established. Here we report on the kinetics of oxidation of thiosulfate, thiourea, thioglycolate, (methylthio)acetate, tetrathionate, dithiodiglycolate, and dithiodipropionate at 25 °C and 0.4 M ionic strength. These reactions obey the general rate law -d[OCl(-)]/dt = (kOCl(-)[OCl(-)] + kHOCl[HOCl])[substrate] with some exceptions: tetrathionate and the two disulfides undergo rate-limiting hydrolysis at high pH, and dithiodiglycolate has an additional term in the rate law that is second order in [substrate]...
March 14, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28284611/dead-mouse-hopping-tyzzer-s-disease-in-spinifex-hopping-mice-notomys-alexis
#14
Hayley J Stannard, Melissa L Tulk, Julie M Old
Tyzzer's disease is caused by Clostridium piliformes and affects a wide range of domestic and wildlife species. Non-descript signs, if any, and a short incubation period make Tyzzer's disease difficult to diagnose and treat before death occurs. Here we describe an unexpected outbreak of Tyzzer's disease in a colony of native Australian spinifex hopping-mice (Notomys alexis). In this study captive hopping-mice were used in a nutrition trial (n=11), and others were housed in close proximity (n=4). During the nutrition trial, two hopping-mice exhibited signs of lethargy and diarrhoea, and were removed from the trial but died soon after...
March 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28276583/effect-of-photodynamic-therapy-in-combination-with-various-irrigation-protocols-on-an-endodontic-multispecies-biofilm-ex-vivo
#15
D Hoedke, C Enseleit, D Gruner, H Dommisch, S Schlafer, I Dige, K Bitter
AIM: To analyse the antibacterial effect of photodynamic therapy (PDT) in combination with various irrigation protocols on a multispecies biofilm in root canals ex vivo. METHODOLOGY: A total of 160 extracted human single-rooted teeth were divided into four groups (n = 40). In group (G) 1, root canals were instrumented up to size 60 (control group), whereas in G 2 - 4 canals were enlarged up to size 40. All root canals were inoculated with a multispecies biofilm (Enterococcus faecalis, Streptococcus oralis, Prevotella intermedia) for five days...
March 9, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28275851/the-effect-of-chemical-treatments-on-lampenflora-and-a-collembola-indicator-species-at-a-popular-tour-cave-in-california-usa
#16
Erik Meyer, L Don Seale, Brianne Permar, Andrew McClary
Growth of invasive, opportunistic plants (i.e. lampenflora) in popular tour caves is a significant concern for land managers worldwide. Numerous chemicals at various concentrations have been utilized to remove phototrophic lampenflora colonizing artificially lit surfaces within these caves; however formulations, effectiveness, and impacts appear anecdotal and temporally limited. At Crystal Cave, Sequoia National Park, California, we study lampenflora and cave springtail (Tomocerus celsus) response to a single 0...
March 8, 2017: Environmental Management
https://www.readbyqxmd.com/read/28266133/effectiveness-of-a-polyhexanide-irrigation-solution-on-methicillin-resistant-staphylococcus-aureus-biofilms-in-a-porcine-wound-model
#17
Stephen C Davis, Andrew Harding, Joel Gil, Fernando Parajon, Jose Valdes, Michael Solis, Alex Higa
Irrigation and removal of necrotic debris can be beneficial for proper healing. It is becoming increasingly evident that wounds colonized with biofilm forming bacteria, such as Staphylococcus aureus (SA), can be more difficult to eradicate. Here we report our findings of the effects of an irrigation solution containing propyl-betaine and polyhexanide (PHMB) on methicillin-resistant Staphylococcus aureus (MRSA) biofilms in a porcine wound model. Thirty-nine deep partial thickness wounds were created with six wounds assigned to one of six treatment groups: (i) PHMB, (ii) Ringer's solution, (iii) hypochlorous acid/sodium hypochlorite, (iv) sterile water, (v) octenidine dihydrochloride, and (vi) octenilin...
March 7, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28263585/acute-responses-of-microorganisms-from-membrane-bioreactors-in-the-presence-of-naocl-protective-mechanisms-of-extracellular-polymeric-substances
#18
Xiaomeng Han, Zhiwei Wang, Mei Chen, Xingran Zhang, Chuyang Y Tang, Zhichao Wu
Extracellular polymeric substances (EPS) are key foulants in membrane bioreactors (MBRs). However, their positive functions of protecting microorganisms from environmental stresses, e.g., during in situ hypochlorite chemical cleaning of membranes, have not been adequately elucidated. In this work, we investigated the response of microorganisms in an MBR to various dosages of NaOCl, with a particular emphasis on the mechanistic roles of EPS. Results showed that functional groups in EPS such as the hydroxyl and amino groups were attacked by NaOCl, causing the oxidation of polysaccharides, denaturation of amino acids, damage to protein secondary structure, and transformation of tryptophan protein-like substances to condensed aromatic ring substances...
March 21, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28258812/antibacterial-efficacy-of-octenisept-alexidine-chlorhexidine-and-sodium-hypochlorite-against-enterococcus-faecalis-biofilms
#19
Sundus Bukhary, Hanan Balto
INTRODUCTION: The purpose of this study was to evaluate the antibacterial effectiveness of Octenisept (OCT; Schülke & Mayr GmBH, Norderstedt, Germany), 1% alexidine (ALX) (Santa Cruz Biotechnology, Inc, Santa Cruz, CA), and 2% chlorhexidine (CHX) against Enterococcus faecalis biofilm using confocal laser scanning microscopy. METHODS: Root dentin discs were prepared from extracted human teeth, sterilized, and inoculated with E. faecalis strain (ATCC 29212) to establish 3-week-old biofilm model...
February 28, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28258273/additive-and-reducing-effects-between-calcium-hydroxide-and-current-irrigation-solutions
#20
Zahed Mohammadi, Hamid Jafarzadeh, Sousan Shalavi, Rasoul Sahebalam, Jun Ichiro Kinoshita
Microorganisms should be considered to have the major role in starting and perpetuation of pulpo-periapical diseases. Using intracanal medicaments is necessary to gain a bacteria-free environment in the canal system. Calcium hydroxide (abbreviated as Ca(OH)2), which is the most commonly used medicament in endodontic therapy, has been shown to be effective against primary sources of infection; however, its effectiveness against some microorganisms, such as Candida albicans and Enterococcus faecalis has not been proved...
March 1, 2017: Journal of Contemporary Dental Practice
keyword
keyword
86992
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"