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sinonasal papillomas

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https://www.readbyqxmd.com/read/28722237/bone-involvement-histopathological-evidence-for-endoscopic-management-of-sinonasal-inverted-papilloma
#1
Na Liang, Zhenxiao Huang, Honggang Liu, Junfang Xian, Qian Huang, Bing Zhou
OBJECTIVE: The aim of this study is to provide histopathological evidence for a better understanding of the excision of bone underlying tumor. STUDY DESIGN: Retrospective study. METHODS: Thirty patients with histopathological diagnosis of sinonasal inverted papilloma (SIP) were enrolled. All patients underwent preoperative radiography to define the tumor location. The primary tumor and underlying bone, removed during endoscopic surgery, were examined under microscope...
July 19, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28699194/inverted-schneiderian-papilloma-of-the-supraglottis-case-report
#2
Robert Saddawi-Konefka, Nosaibah Hariri, Ahmed Shabaik, Philip A Weissbrod
Inverted schneiderian papillomas are rare benign tumors, most often arising from the sinonasal mucosa. We describe a case of a 59-year-old female with an inverted papilloma of the supraglottis. This is the first reported case of a supraglottic-presenting inverted papilloma. Although rare, this case demonstrates that these tumors should be considered during workup of supraglottic laryngeal masses. Laryngoscope, 2017.
July 12, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28693263/role-of-microrna-296-3p-in-the-malignant-transformation-of-sinonasal-inverted-papilloma
#3
Tomohiko Kakizaki, Hiromitsu Hatakeyama, Yuji Nakamaru, Dai Takagi, Takatsugu Mizumachi, Tomohiro Sakashita, Satoshi Kano, Akihiro Homma, Satoshi Fukuda
Inverted papilloma (IP) is a benign tumor occurring in the nasal cavity and paranasal sinuses. It is reported that 5-15% of IPs undergo malignant transformation into squamous cell carcinoma (SCC), and the role of microRNAs (miRNA/miR) in this process remains to be elucidated. In the present study, whole miRNA profiles using samples of IP and SCC were investigated, in order to detect the function of miRNA in the carcinogenesis of IP. Samples from IPs (n=5) and SCC lesions (n=5), which arose from IPs, were used for miRNA analysis...
July 2017: Oncology Letters
https://www.readbyqxmd.com/read/28689974/endoscopic-surgery-for-sinonasal-tumors-the-transcribriform-approach
#4
R Thomas, P Martin, D Patrick, M Justin
Over the past 10 to 20 years, endoscopic endonasal surgery has become for many teams the preferred treatment for sinonasal tumors. Technical advances in the field of surgical instrumentation (good visualization, hemostasis…) and the progress of imaging guidance (to avoid neurovascular complication) has made those procedures simpler and safer. Nevertheless, endonasal endoscopic procedures require a trained surgical team of ENT specialist and neurosurgeon. Endoscopic endonasal surgery has been reported to be feasible for all types of sinonasal tumors whether benign tumors such as inverted papillomas, or malignant tumors...
July 8, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28639124/low-grade-papillary-schneiderian-carcinoma-a-case-report
#5
Hui-Jeong Jeong, Jin Roh, Bong-Jae Lee, Kyung-Ja Cho
The nasal cavity and paranasal sinuses are covered with ciliated respiratory mucosa of ectodermal origin, known as Schneiderian epithelium, which can give rise to different types of sinonasal carcinomas. A 42-year-old woman with a history of nasal polypectomy 3 years previously presented with nasal obstruction and rhinorrhea. She was found to have a papillary mass involving the left nasal cavity, and the left maxillary and ethmoidal sinuses by radiologic examination. She underwent endonasal resection under the diagnosis of oncocytic papilloma...
June 21, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28635991/the-papillomas-of-the-sinonasal-tract-a-comprehensive-review
#6
G Leoncini, L Zanetti
Papillomas are uncommon tumors of the sinonasal tract histologically derived from the Schneiderian membrane. Three distinctive variants are described, the exophytic, the inverting and the oncocytic types. On physical examination, their appearance varies from exophytic-fungiform seen in the exophytic variant, to polypoid-papillary in both the inverting and oncocytic variant. The presence of an asymptomatic mass or epistaxis and unilateral nasal obstruction are the typical presenting symptoms. Clinically they tend to recur and, although benign, they may erode the bone laminas by pressure, especially the inverting type, causing proptosis and other co-morbidities...
March 2017: Pathologica
https://www.readbyqxmd.com/read/28620639/prevalence-of-human-papilloma-virus-in-sinonasal-papilloma-in-southern-iranian-population
#7
Behnaz Valibeigi, Mohamad Javad Ashraf, Narges Kerdegari, Akbar Safai, Elham Abedi, Bijan Khademi, Negar Azarpira
STATEMENT OF THE PROBLEM: Sinonasal papilloma (SNP) is a rare benign lesion characterized by high recurrence rate and malignant transformation. PURPOSE: This study aimed to investigate the prevalence of human papilloma virus (HPV) infection in these lesions in South of Iran. MATERIALS AND METHOD: In this cross sectional retrospective study, a total of 41 patients, 38 SNP and 3 SNP/Squamous cell carcinoma cases, from 2007 to 2014 were studied...
June 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28599459/advances-in-recurrence-and-malignant-transformation-of-sinonasal-inverted-papillomas
#8
Qingjia Sun, Lifeng An, Jun Zheng, Dongdong Zhu
Sinonasal inverted papilloma (SIP) is a benign tumor of the nasal cavity and sinus. SIP is characterized by aggressive malignant transformation and a high rate of recurrence. Inadequate removal of the tumor during surgery is one of the most significant contributors to SIP recurrence. A growing body of evidence suggests that molecular alteration in SIP, including human papilloma virus infections, single nucleotide polymorphisms of key genes, deregulation of signaling pathways and immunological changes, may lead to SIP occurrence and malignant transformation...
June 2017: Oncology Letters
https://www.readbyqxmd.com/read/28597339/the-clinical-behavior-of-sinonasal-inverted-papilloma-with-cellular-dysplasia-case-series-and-review-of-the-literature
#9
Ahmad Safadi, Daniel Yafit, Sara Abu-Ghanem, Omer J Ungar, Anat Wengier, Avraham Abergel, Dan M Fliss, Ilan Koren
The prognosis and recurrence rate of inverted papilloma (IP) with concomitant cellular dysplasia are not well-delineated. Demographic, clinical and imaging data of all patients who were surgically treated for sinonasal inverted papilloma (SNIP) in our center between 1996 and 2013 were reviewed. Data regarding the coexistence of dysplastic changes or malignancy within the resected tissues were also retrieved. After the exclusion of malignant cases and patients who were lost for follow-up, 92 patients were included in the study...
June 8, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28586604/orbital-involvement-in-sinonasal-diseases
#10
Zia-Us-Salam Qazi, Sarfraz Latif, Sadia Maqsood Awan
BACKGROUND: Orbital involvement in sinonasal diseases can present as proptosis, ophthalmoplegia or even as blindness due to optic nerve damage. There are a number of sinonasal diseases which can involve eyes. The purpose of this study was to enlist diagnoses of all the patients with sinonasal disease, in which orbit was also involved unilaterally or bilaterally and to analyse the management strategy and final outcome in all the cases. METHODS: Hundred consecutive patients having orbital symptoms along with sinonasal complaints that presented in ENT department of Shaikh Zayed federal postgraduate medical institute were included in our prospective study...
October 2016: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28583236/complete-response-of-skull-base-inverted-papilloma-to-chemotherapy-case-report
#11
Edward C Kuan, John W Frederick, Miguel F Palma Diaz, Dean W Lim, Jeffrey D Suh
BACKGROUND: Inverted papilloma (IP) is the most common benign sinonasal neoplasm. Endoscopic techniques, improved understanding of pathophysiology, and novel surgical approaches have allowed rhinologists to treat IPs more effectively, with surgery being the mainstay of therapy. Frontal sinus IP poses a challenge for surgical therapy due to complex anatomy and potentially difficult surgical access. OBJECTIVES: We reported a unique case of a massive frontal sinus IP that presented with intracranial and orbital extension, with near resolution after chemotherapy...
June 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/28490410/recurrence-of-sinonasal-inverted-papilloma-following-surgical-approach-a-meta-analysis
#12
Ronald G Amedee
No abstract text is available yet for this article.
May 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28485293/the-rapid-change-in-sinonasal-inverted-papilloma-incidence-the-epidemiological-analysis
#13
Roland Zydroń, Grażyna Greczka, Małgorzata Wierzbicka
In recent years, the incidence of sinonasal inverted papilloma (IP) in a stable population has increased significantly. The aim of the study was to analyze the occurrence of IP between the years 2002-2012 in relation to epidemiological factors in an unalterable area. Moreover, we wanted to start a discussion about the difficulties in determining the inci¬dence of benign lesions that are not included in registers. This retrospective study included a group of 69 patients who were treated in the Department of Otolaryngology, ENT Oncology, Poznań University of Medical Sciences...
February 28, 2017: Otolaryngologia Polska
https://www.readbyqxmd.com/read/28485287/clinical-outcomes-of-treatment-of-sinonasal-inverted-papillomas-ips-depending-on-the-surgical-technique-and-learning-curve
#14
Roland Zydroń, Małgorzata Wierzbicka, Grażyna Greczka
INTRODUCTION: Sinonasal inverted papillomas (IPs) are a major challenge for ENT specialists. In the last decades, the number of endoscopic procedures has increased, while the percentage of external or double approach procedures has decreased. The aim of this study was to evaluate long-term IP treatment outcomes according to the applied surgical method. MATERIAL AND METHODS: the retrospective study included 69 patients (28 women and 41 men) treated during 2002-2012 in the Department of Otolaryngology and Laryngological Oncology of Poznań University of Medical Sciences...
November 20, 2016: Otolaryngologia Polska
https://www.readbyqxmd.com/read/28485285/endoscopic-surgical-management-of-sinonasal-inverted-papilloma-extending-to-frontal-sinuses
#15
Yukiko Takahashi, Fumi Shoji, Yukio Katori, Hiroshi Hidaka, Naoya Noguchi, Yasuhiro Abe, Risako Kakuta Kakuta, Takahiro Suzuki, Yusuke Suzuki, Nobuo Ohta, Seiji Kakehata, Yoshitaka Okamoto
OBJECTIVE: Sinonasal inverted papilloma has been traditionally managed with external surgical approaches. Advances in imaging guidance systems, surgical instrumentation, and intraoperative multi-visualization have led to a gradual shift from external approaches to endoscopic surgery. However, for anatomical and technical reasons, endoscopic surgery of sinonasal inverted papilloma extending to the frontal sinuses is still challenging. Here, we present our experience in endoscopic surgical management of sinonasal inverted papilloma extending to one or both frontal sinuses...
November 10, 2016: Otolaryngologia Polska
https://www.readbyqxmd.com/read/28479047/the-analysis-of-expression-of-p16-protein-in-group-of-53-patients-treated-for-sinonasal-inverted-papilloma
#16
Roland Zydroń, Andrzej Marszałek, Magdalena Bodnar, Paweł Kosikowski, Grażyna Greczka, Małgorzata Wierzbicka
INTRODUCTION: Sinonasal Inverted Papilloma (IP) constitute relevant therapeutic problem due to destructive character of growth, tendency to recur and the possibility of malignant transformation. Therefore, many attempts to identify risk factors for IP occurrence have been undertaken, as well as research to find markers that would allow for the earlier detection of tumors and the application of adequate therapy. A widely known risk factor of IP is HPV infection. One of the markers of HPV infection and the ongoing effect of this change (although arousing some controversy) is the expression of the p16 protein...
April 19, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28473663/expression-pattern-of-estroprogestinic-receptors-in-sinonasal-inverted-papilloma
#17
Agostino Serra, Rosario Caltabiano, Giacomo Spinato, Salvatore Gallina, Salvatore Caruso, Venerando Rapisarda, Paola Di Mauro, Veronica Castro, Angelo Conti, Luisa Licciardello, Luigi Maiolino, Salvatore Lanzafame, Salvatore Cocuzza
Inverted papilloma (IP) is a locally destructive, benign neoplasm of the nose and paranasal sinuses with a high tendency for recurrence, a significant potential for malignancy, and an etiology that today is still uncertain. The expression of hormonal receptors in neoplastic tissues has been the focus of intensive research for its potential diagnostic, prognostic, and therapeutic significance. The aim of this study was to assess the potential estroprogestinic receptor expression in patients undergoing sinus surgery for IP...
June 13, 2017: Oncotarget
https://www.readbyqxmd.com/read/28444451/new-tumor-entities-in-the-4th-edition-of-the-world-health-organization-classification-of-head-and-neck-tumors-nasal-cavity-paranasal-sinuses-and-skull-base
#18
REVIEW
Lester D R Thompson, Alessandro Franchi
The World Health Organization recently published the 4th edition of the Classification of Head and Neck Tumors, including several new entities, emerging entities, and significant updates to the classification and characterization of tumor and tumor-like lesions, specifically as it relates to nasal cavity, paranasal sinuses, and skull base in this overview. Of note, three new entities (NUT carcinoma, seromucinous hamartoma, biphenotypic sinonasal sarcoma,) were added to this section, while emerging entities (SMARCB1-deficient carcinoma and HPV-related carcinoma with adenoid cystic-like features) and several tumor-like entities (respiratory epithelial adenomatoid hamartoma, chondromesenchymal hamartoma) were included as provisional diagnoses or discussed in the setting of the differential diagnosis...
April 25, 2017: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/28432463/malignant-transformation-of-sinonasal-inverted-papilloma-and-related-genetic-alterations-a-systematic-review
#19
REVIEW
M Re, F M Gioacchini, A Bajraktari, M Tomasetti, S Kaleci, C Rubini, A Bertini, G Magliulo, E Pasquini
Schneiderian papillomas are uncommon tumors which may develop within the nasal cavity and comprise three well-defined histological types: sinonasal inverted papilloma (SNIP), exophytic papilloma, and oncocytic papilloma. It is well known the rate of Schneiderian papilloma may also present a malignant degeneration and SNIP represents the most important subgroup in consideration of its frequency and malignant propensity. Although HPV infection is always considered the first event favoring the development of SNIP, however, it is not established as an eventual connection between viral actions and malignant transformation...
August 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28421830/sinonasal-inverted-papilloma-risk-factors-for-local-recurrence-after-surgical-resection
#20
Quentin Lisan, Ollivier Laccourreye, Pierre Bonfils
OBJECTIVES: Sinonasal inverted papillomas (SIP) present a potential for recurrence years after the surgery, but most studies report short-term follow-up, and risk factors for recurrence are still debated. Furthermore, several classifications are described, and no consensus exists regarding which one should be used. The aims of this study were to report our long-term results, investigate for potential risk factors for recurrence, and compare the existing 8 staging systems. METHODS: Over a 28-year period, 110 patients with a diagnosis of SIP were enrolled...
June 2017: Annals of Otology, Rhinology, and Laryngology
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