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sinonasal papillomas

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https://www.readbyqxmd.com/read/29909780/sinonasal-papilloma-what-influences-the-decision-to-request-a-magnetic-resonance-imaging-scan
#1
A V Kasbekar, C Swords, B Attlmayr, T Kulkarni, A C Swift
BACKGROUND: Computed tomography is the standard pre-operative imaging modality for sinonasal papilloma. The complementary use of magnetic resonance imaging as an additional investigation is debated. This study aimed to establish whether magnetic resonance imaging can accurately detect tumour extent and is a useful adjunct to computed tomography. METHODS: A retrospective review was conducted on 19 patients with sinonasal papilloma. The interpretation of computed tomography and magnetic resonance imaging scans, by three clinicians, was conducted by comparing prediction of tumour extent...
June 18, 2018: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/29879069/oncocytic-schneiderian-papilloma-associated-adenocarcinoma-and-kras-mutation-a-case-report
#2
Lichuan Zhang, Chunhua Hu, Xiaodan Zheng, Dawei Wu, Haili Sun, Wei Yu, Ying Wu, Dong Chen, Qianwen Lv, Ping Zhang, Xiping Li, Honggang Liu, Yongxiang Wei
RATIONALE: Oncocytic Schneiderian papillomas (OSP) are an uncommon type of sinonasal papillomas that arise from the Schneiderian epithelium, accounting for only 6% of all sinonasal papillomas. Malignancies arising in OSP are rare and are almost always described as in situ or invasive squamous cell carcinoma, although mucoepidermoid, small cell carcinoma and sinonasal undifferentiated carcinoma have also been reported. To our knowledge, only 18 such instances have been reported in the medical literature...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29873223/-human-papillomavirus-infection-and-sinonasal-inverted-papilloma
#3
REVIEW
D Wu, C S Wang, L Zhang
Sinonasal inverted papilloma is the most common seen benign disease of nasal cavities and paranasal sinuses area characterized by great recurrence rate and malignancy tendency. The infection of human papillomavirus is considered as a risk factor playing a role underneath the mechanism. However, the association between the infection of HPV and the recurrence or malignancy of SNIP remains controversial. By summarizing the existing research results, this paper further explores the association between HPV infection and SNIP...
May 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29798318/-analysis-of-the-recurrence-related-factors-of-sinonasal-inverted-papilloma
#4
M H Wang, B Guan, A M Yu, B Y Dai, Q Yan, S S Chen
Objective: To evaluate the influence risk factors of recurrence and the methods for reducing recurrence of sinonasal inverted papilloma (SNIP). Method: Clinical data of 34 patients with SNIP were analyzed retrospectively. All of them were unilateral onset. The diagnosis was confirmed pathologically and the range of lesions was determined by endoscopic and imaging examination; clinical classification according to Krouse classification method; All operations were performed under nasal endoscope, of which 20 cases were operated by simple nasal endoscope, and 14 cases were operated by endoscopic anterior lacrimal recess approach...
December 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29798313/-a-study-on-p16-and-hpv16-in-sinonasal-squamous-cell-carcinoma
#5
J S Wang, A H Yan
Objective: The aim of this study is to evaluate the relationship between the expression of P16 and infection of HPV16 in sinonasal squamous cell carcinoma and its clinical and pathological features, futher prognosis was also investigated. Method: Fifty-five cases of sinonasal squamous cell carcinoma were collected,twenty cases of nasal in-verted papilloma and twenty cases of nasal polyp were chose as control. The expression of P16 and infection of HPV16 were detected by immunohistochemistry in both experimental group and control group...
December 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29779136/genetic-mutation-analysis-of-the-malignant-transformation-of-sinonasal-inverted-papilloma-by-targeted-amplicon-sequencing
#6
Shinichiro Yasukawa, Satoshi Kano, Hiromitsu Hatakeyama, Yuji Nakamaru, Dai Takagi, Takatsugu Mizumachi, Masanobu Suzuki, Takayoshi Suzuki, Akira Nakazono, Shinya Tanaka, Hiroshi Nishihara, Akihiro Homma
BACKGROUND: The mechanism underlying the malignant transformation of inverted papilloma (IP) has not yet been elucidated. METHODS: To clarify the genes responsible for the malignant transformation, we analyzed 10 cases of IP, 8 of IP with dysplasia, and 11 of squamous cell carcinoma (SCC) by targeted amplicon sequencing. RESULTS: The number of mutant genes increased in the order of IP < dysplasia < SCC. Significant differences were observed in the mutation rates of three genes (KRAS, APC and STK11) in particular...
May 19, 2018: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29764790/a-case-of-inverted-papilloma-of-the-mastoid-cavity-after-cholesteatoma-surgery
#7
Goh Eui-Kyung, Cho Ilyoung, Oh Se-Joon, Choi Sung-Won, Kim Young-Keum
An inverted papilloma is a benign neoplasm that occurs exclusively in the sinonasal cavity; an inverted papilloma involving the mastoid cavity is extremely rare. We present the case of a patient with an inverted papilloma of the mastoid cavity secondary to cholesteatoma surgery. No case that occurred after acquired cholesteatoma has been reported in literature. A 39-year-old female who was diagnosed with cholesteatoma was treated with a modified radical mastoidectomy in 1988. After recurrence, the patient underwent a canal wall down mastoidectomy in 2006...
April 2018: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29763337/raman-spectroscopy-for-inverted-papilloma-a-proof-of-concept-study
#8
Marco A Mascarella, Abdulaziz Alrasheed, Naif Fnais, Ophelie Gourgas, Ghulam Jalani, Marta Cerruti, Marc A Tewfik
Inverted papillomas are tumors of the sinonasal tract with a propensity to recur. Raman spectroscopy can potentially identify inverted papillomas from other tissue based on biochemical signatures. A pilot study comparing Raman spectroscopy to histopathology for 3 types of sinonasal tissue was performed. Spectral data of biopsies from patients with normal sinonasal mucosa, chronic rhinosinusitis, and inverted papillomas are compared to histopathology using principal component analysis and linear discriminant analysis after data preprocessing...
May 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29737509/optical-coherence-tomography-and-confocal-laser-scanning-microscopy-as-non-invasive-tools-in-the-diagnosis-of-sinonasal-inverted-papilloma-a-pilot-study
#9
Attila Óvári, N Starke, T Schuldt, S Schröder, S Zonnur, A Erbersdobler, E Lankenau, O Stachs, T Just, R Mlynski, B Olzowy
Optical coherence tomography (OCT) and confocal laser scanning microscopy (CLSM) are light-based imaging techniques that allow for a visualization of microscopic tissue properties in vivo. Our study was to examine whether they allow for differentiation of inverted papilloma (IP) from nasal polyps (NP). Five cases of IP and NP, respectively, were investigated intraoperatively with OCT and CLSM. Biopsies were taken of the investigated area and were analyzed ex vivo with OCT and CLSM and then underwent HE-staining for standard light microscopy...
May 8, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29696477/imaging-features-of-benign-mass-lesions-in-the-nasal-cavity-and-paranasal-sinuses-according-to-the-2017-who-classification
#10
REVIEW
Hiroyuki Tatekawa, Taro Shimono, Masahiko Ohsawa, Satoshi Doishita, Shinichi Sakamoto, Yukio Miki
The World Health Organization (WHO) 2017 classification of head and neck tumors has been just published and has reorganized tumors of the nasal cavity and paranasal sinuses. In this classification, three new entities (seromucinous hamartoma, NUT carcinoma, and biphenotypic sinonasal sarcoma) were included, while the total number of tumors has been reduced by excluding tumors if they did not occur exclusively or predominantly in this region. Among these entities, benign tumors were classified as sinonasal papillomas, respiratory epithelial lesions, salivary gland tumors, benign soft tissue tumors, or other tumors...
June 2018: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/29678350/better-surgical-outcome-by-image-guided-navigation-system-in-endoscopic-removal-of-sinonasal-inverted-papilloma
#11
Sang Hyeon Ahn, Eun Jung Lee, Jin Won Kim, Kwang Ha Baek, Hyung-Ju Cho, Joo-Heon Yoon, Chang-Hoon Kim
PURPOSE: The purpose of this study was to validate and compare treatment outcomes for endoscopic resection of sinonasal inverted papilloma (IP) with or without the use of a navigation system. MATERIALS AND METHODS: A total of 58 patients who underwent endoscopic resection of sinonasal inverted papilloma by a single surgeon from 2007 to 2016 at our institution were retrospectively reviewed. Depending on the use of the navigation system, subjects were divided into two groups: a conventional endoscopic resection group without navigation system (CER group) and a navigation-assisted endoscopic resection group (NER group)...
June 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29669359/low-ct-attenuation-values-of-sinonasal-benign-tumours-relative-to-the-brainstem-identify-schwannomas
#12
Tomoaki Nakada, Shu Kikuta, Harushi Mori, Yuya Shimizu, Hironobu Nishijima, Kenji Kondo, Tatsuya Yamasoba
OBJECTIVES: On computed tomography (CT), sinonasal schwannoma displays as a soft-tissue mass without any distinctive features. Our aim was to define the radiological criteria for distinguishing schwannoma from other sinonasal benign tumours. METHODS: We retrospectively identified consecutive patients who were pathologically diagnosed with benign sinonasal tumours between 2007 and 2016. CT attenuation values were compared between benign tumours and the brainstem...
2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/29668071/human-papillomavirus-an-unlikely-etiologic-factor-in-sinonasal-inverted-papilloma
#13
Sepideh Mohajeri, Chi Lai, Bibianna Purgina, Dakheelallah Almutairi, Tabassom Baghai, Jim Dimitroulakos, Shaun Kilty
OBJECTIVES/HYPOTHESIS: Tenuous evidence has supported the hypothesis that sinonasal inverted papilloma (SNIP) arise from human papillomavirus (HPV) infection. To clarify the role of HPV in SNIP, all known HPV sub-types were evaluated by employing a robust polymerase chain reaction-based method in a wide variety of SNIPs from a single institution. STUDY DESIGN: Retrospective surgical specimen tumor sample analysis. METHODS: HPV positivity among SNIP samples and those with squamous cell carcinoma (SCC) were compared...
April 18, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29649889/endoscopic-resection-of-sinonasal-inverted-papillomas-systematic-review-and-meta-analysis
#14
John K Goudakos, Sarantis Blioskas, Angelos Nikolaou, Konstantinos Vlachtsis, Peter Karkos, Konstantinos D Markou
Background Pure endoscopic surgery (functional endoscopic sinus surgery) has been increasingly replacing external approaches in the management of sinonasal inverted papillomas. Objective To analyze and compare the effectiveness of pure endoscopic procedure with external or combined procedures to paranasal inverted papillomas, including the experience from two institutions in North Greece, over a 20-year period. Methods Systematic literature searches of MEDLINE (1952-2016), EMBASE (1974-2016), and the Cochrane Central Register of Controlled Trials...
May 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29644904/survivin-and-cortactin-expression-in-sinonasal-schneiderian-inverted-papilloma-and-associated-carcinoma
#15
Gino Marioni, Giuseppe Brescia, Lorenzo Nicolè, Rosario Marchese-Ragona, Umberto Barion, Luciano Giacomelli, Filippo Marino, Alessandro Martini, Giancarlo Ottaviano
BACKGROUND: Sinonasal inverted (schneiderian) papilloma (IP) is histologically benign but shows a propensity for malignant transformation. Survivin, a member of the inhibitor of the apoptosis family of proteins that controls cell division, apoptosis, metastasis, and, probably, also neoangiogenesis, is overexpressed in essentially all human cancers. Overexpression of the multidomain protein cortactin has also been associated with increased cell migration, invasion, and metastatic potential in several malignancies...
March 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29622347/optical-imaging-with-a-high-resolution-microendoscope-to-identify-sinonasal-pathology
#16
Sarah M Kidwai, Arjun K Parasher, Victor J Schorn, Elizabeth G Demicco, Rebecca Richards-Kortum, Alfred Marc Iloreta, Satish Govindaraj, Brett A Miles
OBJECTIVES: High-resolution microendoscopy (HRME) is an optical imaging modality that allows real time imaging of epithelial tissue and structural changes within. We hypothesize that HRME, using proflavine, a contrast agent that preferentially stains cell nuclei and allows detection of cellular morphologic changes, can distinguish sinonasal pathology from uninvolved mucosa, potentially enabling real-time surgical margin differentiation. STUDY DESIGN: Ex vivo imaging of histopathologically confirmed samples of sinonasal pathology and uninvolved, normal sinus epithelium...
July 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29607821/human-papilloma-virus-hpv-in-sinonasal-papillomas-and-squamous-cell-carcinomas-a-pcr-based-study-of-60-cases
#17
Ambreen Beigh, Ruby Rashi, Sheikh Junaid, Mehnaz Sultan Khuroo, Summyia Farook
This study was carried out to observe the association of Human Papilloma Virus (HPV) with papillomas and squamous cell carcinomas of the sinonasal region. The present study was a hospital-based study conducted over a period of three years from May, 2014 to May, 2017 in the Department of Pathology, Government Medical College, Srinagar. A total of 196 cases of non-neoplastic and neoplastic lesions of nasal cavity and paranasal sinuses were observed during the study period. Out of total 196 cases, 102 were non-neoplastic and 94 were neoplastic...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29548524/clinical-features-of-nasal-and-sinonasal-inverted-papilloma-associated-with-malignancy
#18
Takuya Miyazaki, Yasuharu Haku, Akira Yoshizawa, Ken Iwanaga, Takashi Fujiwara, Masanobu Mizuta, Atsuhiro Yoshida, Shinichi Satou, Hisanobu Tamaki
OBJECTIVE: Nasal and sinonasal inverted papilloma (IP) are rare benign tumors and have the potential to exhibit malignancy in approximately 10% of cases. This study aimed to analyze the clinical features of IP associated with malignancy. Furthermore, we reviewed our therapeutic strategy and the clinical course of malignant IP. METHODS: Overall, 70 patients with IP at our institution were retrospectively analyzed from April 2006 to December 2015; of these, six (9%) had associated malignancy...
March 13, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29547549/hpv-virus-transcriptional-status-assessment-in-a-case-of-sinonasal-carcinoma
#19
Gennaro Ilardi, Daniela Russo, Silvia Varricchio, Giovanni Salzano, Giovanni Dell'Aversana Orabona, Virginia Napolitano, Rosa Maria Di Crescenzo, Alessandra Borzillo, Francesco Martino, Francesco Merolla, Massimo Mascolo, Stefania Staibano
Human Papilloma Virus (HPV) can play a causative role in the development of sinonasal tract malignancies. In fact, HPV may be the most significant causative agent implicated in sinonasal tumorigenesis and is implicated in as many as 21% of sinonasal carcinomas. To date, there are no definitive, reliable and cost-effective, diagnostic tests approved by the FDA for the unequivocal determination of HPV status in head and neck cancers. We followed an exhaustive algorithm to correctly test HPV infection, including a sequential approach with p16INK4a IHC, viral DNA genotyping and in situ hybridization for E6/E7 mRNA...
March 16, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29459588/magnetic-resonance-imaging-in-evaluation-of-sinonasal-masses-with-histopathological-correlation
#20
M S Begum, U K Sarker, M A Islam, M A Sangma, P Paul, M A Rahman
Sinonasal mass is the abnormal growth of tissue from nasal cavity and mucosa of the paranasal sinuses. The growth may be benign or malignant. The benign lesion grows slowly and does not metastasize. The malignant lesion grows rapidly and metastasizes early. The aim of this study is to evaluate and diagnose the various types of sinonasal masses with MRI and its correlation with histopathological findings. This cross sectional descriptive study was carried out for a period of 02 years, from July 2015 to June 2017...
January 2018: Mymensingh Medical Journal: MMJ
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