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Lumbar spondylosis

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https://www.readbyqxmd.com/read/28857901/two-unique-cases-of-ciprofloxacin-associated-avulsion-of-ligament-and-tendon
#1
Jeffrey David Smith, Robert W Irwin, Erin T Wolff
Ciprofloxacin is recognized to have a deleterious relationship with tendons, particularly Achilles tendinopathy, which makes up most case reports. Tendinopathy seems to occur because of induction of collagen-degrading enzymes causing damage and ischemia of the poorly vascularized regions preventing repair. The focus on the relationship of ciprofloxacin and the Achilles tendon leaves patients on fluoroquinolones with non-Achilles tendinopathy symptoms at risk of misdiagnosis. There have not been any documented instances of ligament damage with ciprofloxacin administration in the literature, although ligament and tendon compositions are similar and should have similar susceptibility...
August 25, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28735763/platelet-rich-plasma-enhances-bone-union-in-posterolateral-lumbar-fusion-a-prospective-randomized-controlled-trial
#2
Go Kubota, Hiroto Kamoda, Sumihisa Orita, Kazuyo Yamauchi, Yoshihiro Sakuma, Yasuhiro Oikawa, Kazuhide Inage, Takeshi Sainoh, Jun Sato, Michihiro Ito, Masaomi Yamashita, Junichi Nakamura, Takane Suzuki, Kazuhisa Takahashi, Seiji Ohtori
BACKGROUND CONTEXT: Platelet-rich plasma (PRP) accelerates bone union in vivo in a rodent model of spinal fusion surgery. However, PRP's effect on bone union after spinal surgery remains unclear. PURPOSE: The objective of this study was to evaluate the efficacy of PRP after posterolateral lumbar fusion (PLF) surgery. STUDY DESIGN/SETTING: Single-center prospective randomized controlled clinical trial with 2-year follow-up. PATIENT SAMPLE: The patient sample included a total 62 patients (31 patients in the PRP group or 31 patients in the control group)...
July 20, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28507882/aquaporin-1-expression-in-herniated-human-lumbar-intervertebral-discs
#3
Haydn Hoffman, Aaron W Choi, Victor Chang, Jon Kimball, Alan S Verkman, Rubeen Virani, Brian Kim, Tianyi Niu, Daniel C Lu
STUDY DESIGN: Case series. OBJECTIVE: Intervertebral disc (IVD) degeneration is the cause of spondylosis. The pathogenesis is poorly understood, but disc dehydration often plays a role. In this study, we aim to identify and quantify aquaporin-1 (AQP1) in ex vivo human degenerated IVDs obtained intraoperatively and to investigate the relationship between AQP1 levels and magnetic resonance imaging (MRI) T2 intensity of the disc. METHODS: Ex vivo samples of nucleus pulposus (NP) tissue from lumbar IVDs were obtained from 18 consecutive patients who underwent surgery for disc herniation at L4/5 and L5/S1 level...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28461958/management-of-degenerative-lumbar-spinal-stenosis-an-evidence-based-review
#4
REVIEW
Augusto Covaro, Gemma Vilà-Canet, Ana García de Frutos, Maite T Ubierna, Francesco Ciccolo, Enric Caceres
Lumbar spinal stenosis has become one of the most disabling pathologies in the elderly population.Some additional conditions such as foraminal stenosis or degenerative spondylosis with a history of back pain and leg pain must be considered before treatment.A completely appropriate protocol and unified management of spinal stenosis have not yet been well defined.The objective of this literature review is to provide evidence-based recommendations reflected in the highest-quality clinical literature available to address key clinical questions surrounding the management of degenerative lumbar spinal stenosis...
July 2016: EFORT open reviews
https://www.readbyqxmd.com/read/28413117/structure-specific-movement-patterns-in-patients-with-chronic-low-back-dysfunction-using-lumbar-combined-movement-examination
#5
Aubrey P Monie, Roger I Price, Christopher R P Lind, Kevin P Singer
OBJECTIVE: A test-retest cohort study was conducted to assess the use of a novel computer-aided, combined movement examination (CME) to measure change in low back movement after pain management intervention in 17 cases of lumbar spondylosis. Additionally we desired to use a CME normal reference range (NRR) to compare and contrast movement patterns identified from 3 specific structural pathologic conditions: intervertebral disc, facet joint, and nerve root compression. METHODS: Computer-aided CME was used before and after intervention, in a cohort study design, to record lumbar range of movement along with pain, disability, and health self-report questionnaires in 17 participants who received image-guided facet, epidural, and/or rhizotomy intervention...
June 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28402458/the-influence-of-pelvic-incidence-and-lumbar-lordosis-mismatch-on-development-of-symptomatic-adjacent-level-disease-following-single-level-transforaminal-lumbar-interbody-fusion
#6
Zachary J Tempel, Gurpreet S Gandhoke, Bryan D Bolinger, Nicolas K Khattar, Philip V Parry, Yue-Fang Chang, David O Okonkwo, Adam S Kanter
BACKGROUND: Annual incidence of symptomatic adjacent level disease (ALD) following lumbar fusion surgery ranges from 0.6% to 3.9% per year. Sagittal malalignment may contribute to the development of ALD. OBJECTIVE: To describe the relationship between pelvic incidence-lumbar lordosis (PI-LL) mismatch and the development of symptomatic ALD requiring revision surgery following single-level transforaminal lumbar interbody fusion for degenerative lumbar spondylosis and/or low-grade spondylolisthesis...
June 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28382238/evaluation-and-interventional-management-of-pain-after-vertebral-augmentation-procedures
#7
Jesse Hatgis, Michelle Granville, Robert E Jacobson
INTRODUCTION: A small subset of patients who underwent successful vertebral compression fracture (VCF) augmentation procedures may develop subsequent pain requiring spinal injections. In a retrospective analysis, we determined whether the pain was related to the original fracture site or to another area within the lumbar or thoracic spine. The pain occurred either at the same/adjacent level and/or non-adjacent level as the VCF. Interventional treatments primarily targeted the facet joints, specifically in the form of facet joint blocks and/or radiofrequency ablation to the medial branches...
February 28, 2017: Curēus
https://www.readbyqxmd.com/read/28362212/does-clinical-improvement-of-symptomatic-degenerative-lumbar-disease-impact-obesity
#8
Jacob R Joseph, Zishaan Farooqui, Brandon W Smith, Elyne N Kahn, Xilin Liu, Frank La Marca, Paul Park
OBJECTIVE Obesity and low-back pain associated with degenerative spondylosis or spondylolisthesis are common comorbid conditions. Many patients report that the pain and disability associated with degenerative lumbar disease are key factors in their inability to lose weight. The aim of this retrospective study was to determine if there is an association between improved functional status and weight loss following a successful transforaminal lumbar interbody fusion (TLIF) procedure. METHODS A retrospective cohort study of patients who underwent single-level TLIF was performed...
June 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28358974/the-impact-of-lumbar-spine-disease-and-deformity-on-total-hip-arthroplasty-outcomes
#9
Daniel J Blizzard, Charles Z Sheets, Thorsten M Seyler, Colin T Penrose, Mitchell R Klement, Michael A Gallizzi, Christopher R Brown
Concomitant spine and hip disease in patients undergoing total hip arthroplasty (THA) presents a management challenge. Degenerative lumbar spine conditions are known to decrease lumbar lordosis and limit lumbar flexion and extension, leading to altered pelvic mechanics and increased demand for hip motion. In this study, the effect of lumbar spine disease on complications after primary THA was assessed. The Medicare database was searched from 2005 to 2012 using International Classification of Diseases, Ninth Revision, procedure codes for primary THA and diagnosis codes for preoperative diagnoses of lumbosacral spondylosis, lumbar disk herniation, acquired spondylolisthesis, and degenerative disk disease...
May 1, 2017: Orthopedics
https://www.readbyqxmd.com/read/28303382/a-rare-case-of-non-traumatic-multi-level-bilateral-pedicle-fractures-of-the-lumbar-spine-in-a-60-year-old-patient
#10
Timo Schmid, Paul Heini, Lorin Benneker
INTRODUCTION: We report a 60-year-old patient who sustained non-traumatic, multi-level, bilateral lumbar pedicle fractures in the setting of unilateral lumbar spondylolysis. A possible fracture mechanism is evaluated and a review of the literature is presented. Whereas contralateral pedicle fractures of lumbar vertebrae with unilateral spondylosis are well described in young athletes, there is only one case report of multi-level, bilateral pedicle fractures of the lumbar spine in a young patient who sustained a high-impact motorcycle accident...
May 2017: European Spine Journal
https://www.readbyqxmd.com/read/28278042/a-cell-attracting-composite-of-lumbar-fusion-cage
#11
Busra Gunay, Nesrin Hasirci, Vasif Hasirci
Lumbar fusion cages are devices used in spinal fusion procedures for disorders such as spondylosis and degenerative disc diseases that may occur due to age, trauma or genetic reasons. These devices are most frequently made of metals and polymers. The mechanical properties of such devices should be comparable to the bone to avoid stress shielding. Besides, cages should interact with the cells to prevent extrusion and achieve satisfactory fusion. In this study, poly(methylmethacrylate) (PMMA) and hydroxyapatite (HAp) were compounded to create products with HAp contents up to 40% (w/w), processed by hot melt extrusion and injection molded to produce composites with maximum polymer-mineral interaction...
March 13, 2017: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/28219354/relationship-between-facet-tropism-and-facet-joint-degeneration-in-the-sub-axial-cervical-spine
#12
Xin Rong, Ziyang Liu, Beiyu Wang, Xuelin Pan, Hao Liu
BACKGROUND: Facet tropism is the angular asymmetry between the left and right facet joint orientation. Although debatable, facet tropism was suggested to be associated with disc degeneration, facet degeneration and degenerative spondylolisthesis in the lumbar spine. The purpose of this study was to explore the relationship between facet tropism and facet degeneration in the sub-axial cervical spine. METHODS: A total of 200 patients with cervical spondylosis were retrospectively analyzed...
February 20, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28207315/diagnosis-of-lumbosacral-diskospondylosis-in-a-bucking-bull-assisted-by-high-definition-thermal-and-nuclear-scintigraphic-imaging
#13
Marc Caldwell, Thomas Passler, Ram C Purohit, David Pascoe, Dwight F Wolfe
CASE DESCRIPTION An 8-year-old Brahman-cross bull was evaluated for left hind limb lameness of 2 months' duration. The lameness was first noticed during a rodeo bucking performance, immediately after the bull appeared to land inappropriately on the affected limb. CLINICAL FINDINGS Physical examination findings revealed left hind limb lameness, ataxia, and left-sided epaxial muscle atrophy. Palpation per rectum along the lumbar portion of the vertebral column revealed evidence of exostosis of the ventral aspect...
March 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28139188/sagittal-plane-analysis-of-the-spine-and-pelvis-in-degenerative-lumbar-scoliosis
#14
Fei Han, Li Weishi, Sun Zhuoran, Ma Qingwei, Chen Zhongqiang
BACKGROUND: Previous studies have reported the normative values of pelvic sagittal parameters, but no study has analyzed the sagittal spino-pelvic alignment in degenerative lumbar scoliosis (DLS) and its role in the pathogenesis. METHODS: Retrospective analysis was applied to 104 patients with DLS, together with 100 cases of asymptomatic young adults as a control group and another control group consisting of 145 cases with cervical spondylosis. The coronal and sagittal parameters were measured on the anteroposterior and lateral radiograph of the whole spine in the DLS group as well as in the two control groups...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28097242/anterior-to-psoas-atp-fusion-of-the-lumbar-spine-evolution-of-a-technique-facilitated-by-changes-in-equipment
#15
Cristian Gragnaniello, Kevin Seex
BACKGROUND: Lateral interbody cages have been proven useful in spinal fusions. Spanning both lateral cortical rims while sparing the Anterior Longitudinal Ligament, the lateral interbody cages restore and maintain disc height while adding stability prior to supplemental fixation. The standard approach for their insertion is by a 90-degree lateral transpsoas method. This is relatively bloodless compared to other techniques although has its limitations, requiring neuro-monitoring and being, at times, very difficult at L4/5 due to iliac crest obstruction or an anterior plexus position...
December 2016: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28094419/postoperative-computed-tomography-and-low-field-magnetic-resonance-imaging-findings-in-dogs-with-degenerative-lumbosacral-stenosis-treated-by-dorsal-laminectomy
#16
Martin Rapp, Charles J Ley, Kerstin Hansson, Lennart Sjöström
OBJECTIVES: To describe postoperative computed tomography (CT) and magnetic resonance imaging (MRI) findings in dogs with degenerative lumbosacral stenosis (DLSS) treated by dorsal laminectomy and partial discectomy. METHODS: Prospective clinical case study of dogs diagnosed with and treated for DLSS. Surgical and clinical findings were described. Computed tomography and low field MRI findings pre- and postoperatively were described and graded. Clinical, CT and MRI examinations were performed four to 18 months after surgery...
March 20, 2017: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/28061494/prevalence-and-risk-factors-for-lumbar-spondylosis-and-its-association-with-low-back-pain-among-rural-korean-residents
#17
Sung Yeon Lee, Nam H Cho, Young Ok Jung, Young Il Seo, Hyun Ah Kim
OBJECTIVE: The purpose of this study was to investigate the prevalence of and the relevant risk factors for lumbar spondylosis (LS) among middle-aged and elderly rural Korean residents and to explore the association between radiographic LS and lower back pain (LBP) in relation to age and gender. METHODS: This community-based, cross-sectional study evaluated 1512 subjects with available radiograph. The prevalence of LBP was obtained using a questionnaire and disability resulting from LBP was measured using a validated Korean version of the Oswestry disability index (ODI)...
January 1, 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/27935449/multiple-hook-fixation-in-revision-spinal-deformity-surgery-for-patients-with-a-previous-multilevel-fusion-mass-technical-note-and-preliminary-outcomes
#18
Ning Liu, Kirkham B Wood
OBJECTIVE A previous multilevel fusion mass encountered during revision spinal deformity surgery may obscure anatomical landmarks, making instrumentation unworkable or incurring substantial blood loss and operative time. This study introduced a surgical technique of multiple-hook fixation for fixating previous multilevel fusion masses in revision spinal deformity surgeries and then evaluated its outcomes. METHODS Patients with a previous multilevel fusion mass who underwent revision corrective surgery down to the lumbosacral junction were retrospectively studied...
March 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/27917347/identification-of-lumbar-disc-disease-hallmarks-a-large-cross-sectional-study
#19
Jun Zhang, Fei Zhao, Feng-Liang Wang, Yong-Feng Yang, Chen Zhang, Yue Cao, You-Lin Wang, Xiao-Juan Shi, Yi Wan, Min Zhang, Meng-Qiao Liu, Chun-Guang Zuo, Hai-Qiang Wang
BACKGROUND: Lumbar disc disease has a disabling impact on global people with heavy burden on society, mainly consisting of lumbar disc degeneration (LDD) and lumbar disc herniation (LDH). The recently released lumbar disc nomenclature version 2.0 deepens our understandings on the diseases. Consequently, there is an urgent need to clarify the occurrence and distribution features of LDD and LDH in a large-scale sample in terms of the novel version. QUESTION/PURPOSES: We asked: (1) Is there a difference in the occurrence and distribution hallmarks of LDD and LDH in a population-based large-scale sample? (2) Does the novel nomenclature version bring novel vision on lumbar disc disease? METHODS: Five thousand two hundred eighty-eight consecutive cases (26,440 lumbar discs) undergoing lumbar spine MRI were retrospectively included from Jan 2008 to Dec 2010 in a territory university hospital...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27905911/prevalence-of-lumbar-spondylosis-and-its-association-with-low-back-pain-among-community-dwelling-japanese-women
#20
Ritsu Tsujimoto, Yasuyo Abe, Kazuhiko Arima, Takayuki Nishimura, Masato Tomita, Akihiko Yonekura, Takashi Miyamoto, Shohei Matsubayashi, Natsumi Tanaka, Kiyoshi Aoyagi, Makoto Osaki
BACKGROUND: Lumbar spondylosis is more prevalent among the middle-aged and elderly, but few population-based studies have been conducted, especially in Japan. The purpose of this study was to explore the prevalence of lumbar spondylosis and its associations with low back pain among community-dwelling Japanese women. METHODS: Lateral radiographs of the lumbar spine were obtained from 490 Japanese women ≥ 40 years old, and scored for lumbar spondylosis using the Kellgren-Lawrence (KL) grade at lumbar intervertebral level from L1/2 to L5/S1...
December 1, 2016: BMC Musculoskeletal Disorders
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