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Albane Degrassat-Théas, François Bocquet, Martine Sinègre, Jérôme Peigné, Pascal Paubel
In 2012, following the Mediator(®) (benfluorex) scandal, France displayed the ambitious goal to implement a regulatory framework for controlling off-label drug use: the "Temporary Recommendations for Use" (RTUs). It aims to regulate the use of pharmaceuticals outside the scope of a marketing authorization (MA) by establishing a framework for patient monitoring and data collection. This is intended to ensure that the benefit/risk ratio is favorable for the indication approved by the RTU. The granting of an RTU enables the reimbursement of off-label drug use and encourages pharmaceutical companies to expand their MA...
November 2015: Health Policy
George Suciu, Victor Suciu, Alexandru Martian, Razvan Craciunescu, Alexandru Vulpe, Ioana Marcu, Simona Halunga, Octavian Fratu
Big data storage and processing are considered as one of the main applications for cloud computing systems. Furthermore, the development of the Internet of Things (IoT) paradigm has advanced the research on Machine to Machine (M2M) communications and enabled novel tele-monitoring architectures for E-Health applications. However, there is a need for converging current decentralized cloud systems, general software for processing big data and IoT systems. The purpose of this paper is to analyze existing components and methods of securely integrating big data processing with cloud M2M systems based on Remote Telemetry Units (RTUs) and to propose a converged E-Health architecture built on Exalead CloudView, a search based application...
November 2015: Journal of Medical Systems
Mogens Vyberg, Søren Nielsen
Despite extensive use of immunohistochemistry (IHC) for decades, lack of standardization remains a major problem, even aggravated in the era of targeted therapy. Nordic Immunohistochemical Quality Control (NordiQC) is an international academic proficiency testing (PT) program established in 2003 primarily aimed at assessing the analytical phases of the laboratory IHC quality. About 700 laboratories from 80 countries are currently participating. More than 30,000 IHC slides have been evaluated during 2003-2015...
January 2016: Virchows Archiv: An International Journal of Pathology
Sangeeta Rathi, Anita Zacharias, Rodney A Green
The close proximity of the infraspinatus to the teres minor and their functional similarity in producing external rotation of the glenohumeral joint make accurate insertion of electromyographic (EMG) electrodes into the teres minor difficult and questionable even when published guidelines are followed. The primary aim of this study was to examine the anatomical support for the current guidelines for inserting intramuscular EMG electrodes into the teres minor muscle. The secondary aim was to provide a technical description for ultrasound-guided electrode insertion into the teres minor...
September 2015: Clinical Anatomy
Melvin S Dassinger, Elizabeth J Renaud, Adam Goldin, Eunice Y Huang, Robert T Russell, Christian J Streck, Xinyu Tang, Martin L Blakely
PURPOSE: The purpose of this study was to document the attitudes and practice patterns of pediatric surgeons regarding use of RTUS with CVC placement. METHODS: An analytic survey composed of 20 questions was sent via APSA headquarters to all practicing members. Answers were summarized as frequency and percentage. Distributions of answers were compared using the chi-square tests. P-values ≤0.05 were considered statistically significant. RESULTS: 361 of 1072 members chose to participate for a response rate of 34%...
July 2015: Journal of Pediatric Surgery
Anthony C Camuglia, Malak Majed, Shane D Preston, Shahar Lavi
BACKGROUND: We assessed the value of routine real-time ultrasound (RTUS) guidance to improve transradial access (TRA) for cardiac catheterization. METHODS: A prospective, single-center descriptive observational study of patients presenting for cardiac catheterization via the transradial approach. The first phase of the study enrolled 100 consecutive patients who underwent TRA without the assistance of RTUS followed by 100 consecutive patients who underwent TRA using RTUS guidance...
March 2015: Journal of Invasive Cardiology
Oonagh M Giggins, Ulrik McCarthy Persson, Brian Caulfield
This paper reviews the literature relating to the biofeedback used in physical rehabilitation. The biofeedback methods used in rehabilitation are based on biomechanical measurements and measurements of the physiological systems of the body. The physiological systems of the body which can be measured to provide biofeedback are the neuromuscular system, the respiratory system and the cardiovascular system. Neuromuscular biofeedback methods include electromyography (EMG) biofeedback and real-time ultrasound imaging (RTUS) biofeedback...
2013: Journal of Neuroengineering and Rehabilitation
A C Katheria, S E Fleming, J H Kim
OBJECTIVE: The placement of a peripherally inserted central catheter (PICC) routinely incorporates tip position confirmation using standard radiographs. In this study, we sought to determine whether real-time ultrasound (RTUS) could be used to place a PICC in a shorter time period, with fewer manipulations and fewer radiographs than the use of radiographs to determine accurate placement. STUDY DESIGN: This was a prospective, randomized, trial of infants who required PICC placement...
October 2013: Journal of Perinatology: Official Journal of the California Perinatal Association
Shao-yong Wu, Quan Ling, Long-hui Cao, Jian Wang, Mei-xi Xu, Wei-an Zeng
BACKGROUND: Use of ultrasound-guided techniques to facilitate central venous cannulation (CVC) may reduce the risk of misplacement and complications. A meta-analysis was conducted to compare real-time two-dimensional ultrasound (RTUS) guidance technique with anatomical landmark technique for CVC to determine whether RTUS has any advantages. METHODS: Randomized studies comparing outcomes in patients undergoing CVC with either RTUS or landmark technique were retrieved from PubMed, ISI Web of Knowledge, EMBASE, and OVID EBM Reviews from their inception to March 2012...
February 2013: Anesthesiology
Davina Buntsma, Amanda Stock, Catherine Bevan, Franz E Babl
OBJECTIVE: Suprapubic aspiration (SPA) is the gold standard for obtaining uncontaminated urine specimens in young febrile children. The use of real-time ultrasound (RTUS) has been shown to increase the success rate of SPA. The BladderScan (BSUS) Verathon(®) is an alternative portable ultrasound device designed to provide automated measurement of bladder volume. Although simple and requiring minimal training, there are no data on the success rate of SPA using the device. METHODS: An audit of current SPA practice using BSUS in the ED of a tertiary referral children's hospital was conducted...
December 2012: Emergency Medicine Australasia: EMA
Innes Crawford, Paul B McBeth, Mark Mitchelson, James Ferguson, Corina Tiruta, Andrew W Kirkpatrick
BACKGROUND: Worldwide ultrasound equipment accessibility is at an all-time high, as technology improves and costs decrease. Ensuring that patients benefit from more accurate resuscitation and diagnoses from a user-dependent technology, such as ultrasound, requires accurate examination, typically entailing significant training. Remote tele-mentored ultrasound (RTUS) examination is, however, a technique pioneered in space medicine that has increased applicability on earth. We, thus, sought to create and demonstrate a cost-minimal approach and system with potentially global applicability...
2012: Critical Ultrasound Journal
Manuel Toledano-Ayala, Gilberto Herrera-Ruiz, Genaro M Soto-Zarazúa, Edgar A Rivas-Araiza, Rey D Bazán Trujillo, Rafael E Porrás-Trejo
In this paper a long-range wireless mesh network system is presented. It consists of three main parts: Remote Terminal Units (RTUs), Base Terminal Units (BTUs) and a Central Server (CS). The RTUs share a wireless network transmitting in the industrial, scientific and medical applications ISM band, which reaches up to 64 Km in a single point-to-point communication. A BTU controls the traffic within the network and has as its main task interconnecting it to a Ku-band satellite link using an embedded microcontroller-based gateway...
2011: Sensors
Catherine Bevan, Davina Buntsma, Amanda Stock, Tania Griffiths, Susan Donath, Franz E Babl
OBJECTIVES: Automated bladder ultrasound (ABUS) devices are portable and designed to provide automated measurement of bladder volume. They are simple and require minimal training compared to conventional real-time ultrasound (RTUS). Their most common application in the acute pediatric setting is to assess bladder volumes prior to performing invasive urine collection such as suprapubic aspiration (SPA) in children younger than 2 years of age. However, data on ABUS in young children are limited...
August 2011: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
Irmina Nahon, Gordon Waddington, Roger Adams, Grace Dorey
AIMS: Following surgical removal of the prostate, there may be compromise to the function of the pelvic floor muscles causing continence problems. Assessing the pelvic floor muscles of male patients can be an invasive process that causes discomfort, making it worthwhile to evaluate alternatives to the conventional method of Digital Rectal Examination (DRE). Real time ultrasound (RTUS) has been used with female patients as an alternative to internal assessments. This paper examines the reliability and validity of assessing the male pelvic floor using abdominal RTUS...
September 2011: Neurourology and Urodynamics
Jay A Requarth
BACKGROUND: The use of real-time two-dimensional B-mode ultrasound (RTUS)-aided central venous access device (CVAD) insertion has been recommended by health-care agencies, but a realistic failure rate for bedside attempts is unknown. METHODS: The failure rate of RTUS-aided CVAD insertion is estimated using data from adult inpatients and outpatients referred to a tertiary referral radiology department for a new CVAD insertion during the 2.5-year period ending February 29, 2008...
December 2010: World Journal of Surgery
A La Torre, M Gianferro, G Spera
Plant protection in conventional farming, and even more so in organic farming, requires careful and prudent action agro-environmental monitoring and epidemic risk assessment. Often, however, the plant protection products are distributed in a non-targeted way, even when reduced incidence of pests do not require any treatment. In order to optimize the treatments against downy mildew, multi-annual field trials, both in conventional and organic vineyards, have been carried out. In all farms were considered 3 thesis: 1 untreated control thesis (Test), in order to follow the coarse of infection, 1 standard farm reference thesis (St), where the treatments were carried out according to the usual farm procedures and 1 experimental thesis (X)...
2008: Communications in Agricultural and Applied Biological Sciences
A Jedrzejczak, L S Chipchase
BACKGROUND AND PURPOSE: Real time ultrasound (RTUS) is an emerging imaging modality in physiotherapy. Anecdotal evidence suggests that it is being used as an assessment and biofeedback tool for various deep core stabilizing muscles. However, how and why physiotherapists use RTUS in the clinical setting has not yet been reported. Therefore, this study aimed to establish the availability and usage frequency of RTUS by physiotherapists in South Australia. In addition, the study aimed to describe how physiotherapists were using RTUS and how they were educated in its use...
December 2008: Physiotherapy Research International: the Journal for Researchers and Clinicians in Physical Therapy
R Bugliosi, G Spera, A La Torre, L Campoli, M Scaglione
Most of the forecasting models of Plasmopara viticola infections are based upon empiric correlations between meteorological/environmental data and pathogen outbreak. These models generally overestimate the risk of infections and induce to treat the vineyard even if it should be not necessary. In rare cases they underrate the risk of infection leaving the pathogen to breakout. Starting from these considerations we have decided to approach the problem from another point of view utilizing Artificial Intelligence techniques for data elaboration and analysis...
2006: Communications in Agricultural and Applied Biological Sciences
J I Hwang, Y H Chou, S H Tsay, J H Chiang, C Y Chang, G W Boland, P R Mueller
BACKGROUND: To demonstrate the radiologic-pathologic correlation of adenomyomatosis of gallbladder (GBA) and emphasize the role of high-resolution real-time ultrasound (RTUS) in the diagnosis of GBA. METHODS: Ten (four male and six female, mean age = 49 years) patients with proven GBA (three diffuse, three segmental, and four fundal) diagnosed by histopathology or confirmed by oral cholecystography (OCG) were reviewed. Radiologic studies included OCG (n = 8), RTUS (n = 8), and computed tomography (CT; n = 4)...
January 1998: Abdominal Imaging
J L Leake, J R Hawkins, D Locker
OBJECTIVES: The purpose of this study was to investigate the factors influencing the pattern (amount and types) of dental care provided to dental visitors participating in the baseline stage of the Ontario Study of the Oral Health of Older Adults. METHODS: We interviewed and examined older adults from four municipalities in Ontario and obtained dental service records for the previous two years for those reporting a dental visit. Individual services and their corresponding time and values were aggregated into categories...
1996: Journal of Public Health Dentistry
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