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Axios and stent

Eduardo Rodrigues-Pinto, Todd H Baron
INTRODUCTION: Endoscopic ultrasound guided translumenal drainage of pancreatic fluid collections (PFCs) has been widely practiced for over a decade, using conventional plastic and self-expandable metal stents. The use of such stents for transmural drainage is off-label and limited by the lack of lumen-to-lumen anchorage, which can lead to leakage, migration and tissue trauma. AREAS COVERED: Novel stent designs dedicated to applications of translumenal drainage have recently emerged and promise to make transmural drainage quicker, safer, and more effective...
September 2016: Expert Review of Medical Devices
Carmelo Barbera, Giuseppe Grande, Nadia Alberghina, Mauro Manno, Rita Luisa Conigliaro
No abstract text is available yet for this article.
2016: Endoscopy
Reem Z Sharaiha, Amy Tyberg, Mouen A Khashab, Nikhil A Kumta, Kunal Karia, Jose Nieto, Uzma D Siddiqui, Irving Waxman, Virendra Joshi, Petros C Benias, Peter Darwin, Christopher J DiMaio, Christopher J Mulder, Shai Friedland, David G Forcione, Divyesh V Sejpal, Tamas A Gonda, Frank G Gress, Monica Gaidhane, Ann Koons, Ersilia M DeFilippis, Sanjay Salgado, Kristen R Weaver, John M Poneros, Amrita Sethi, Sammy Ho, Vivek Kumbhari, Vikesh K Singh, Alan H Tieu, Viviana Parra, Alisa Likhitsup, Craig Womeldorph, Brenna Casey, Sreeni S Jonnalagadda, Amit P Desai, David L Carr-Locke, Michel Kahaleh, Ali A Siddiqui
BACKGROUND & AIMS: Endoscopic ultrasound-guided transmural drainage and necrosectomy have become the standard treatment for patients with pancreatic walled-off necrosis (WON). Lumen-apposing metal stents (LAMS) have shown success in the management of pancreatic fluid collections. However, there are few data on their specific roles in management of WON. We investigated the efficacy and safety of LAMS in treatment of WON. METHODS: We performed a retrospective multicenter case series of 124 patients with WON who underwent endoscopic transmural drainage by using LAMS at 17 tertiary care centers from January 2014 through May 2015...
May 14, 2016: Clinical Gastroenterology and Hepatology
Rashmee Patil, Mel A Ona, Charilaos Papafragkakis, Sury Anand, Sushil Duddempudi
Pancreatic fluid collections (PFCs) have conventionally been treated with surgery, percutaneous drainage, or with the more recently established endoscopic ultrasound (EUS)-guided drainage modality. Currently, endoscopic plastic or metallic stents are used for PFC drainage. Plastic stents present issues with stent migration and premature occlusion requiring frequent stent exchanges or placement of additional stents. Metallic stents are tubular and may migrate, resulting in inefficient drainage, content leakage, retrieval and replacement, and possible mucosal injury...
April 2016: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
Rastislav Kunda, Manuel Pérez-Miranda, Uwe Will, Sebastian Ullrich, Dirk Brenke, Markus Dollhopf, Michelle Meier, Alberto Larghi
BACKGROUND: A novel lumen-apposing, self-expanding metal stent to perform EUS-guided drainage procedures has been recently developed. The aim of this study was to analyze the safety, technical and clinical effectiveness of this device for EUS-guided choledochoduodenostomy (EUS-CD) with palliative intent. METHODS: Retrospective analysis of all consecutive patients with unresectable malignant distal bile duct obstruction who, between March 2012 and September 2014, underwent EUS-CD using the study devices (AXIOS™ and Hot AXIOS™, Xlumena Inc...
March 11, 2016: Surgical Endoscopy
Felipe Martínez Alcalá, Felipe R Martínez-Alcalá García, Andres Sánchez-Yague, Alvaro Martínez-Alcalá García, Jose Antonio Ciria Avila, Jose Manuel Perez Pozo
No abstract text is available yet for this article.
2015: Endoscopy
Kenneth F Binmoeller, Ioana Smith, Monica Gaidhane, Michel Kahaleh
OBJECTIVE: Transluminal pseudocyst drainage with currently available tools remains technically challenging, time consuming and limited to fluid collections adherent to the GI tract. Multiple tools and steps are still required to achieve pseudocyst drainage. We evaluated a novel kit to facilitate endoscopic ultrasonography (EUS)-guided access, drainage and rapid decompression in a porcine model. METHODS: The kit consists of the NAVIX access device and the AXIOS stent delivery system...
October 2012: Endoscopic Ultrasound
Joan B Gornals, Carlos De la Serna-Higuera, Andrés Sánchez-Yague, Carme Loras, Andrés M Sánchez-Cantos, Manolo Pérez-Miranda
BACKGROUND: The purpose of this study is to report our initial experience with a new fully covered metallic stent with a novel design (AXIOS) to prevent migration and fluid leakage, in the drainage of pancreatic fluid collections (PFC). METHODS: We included nine patients from four Spanish centers undergoing endoscopic ultrasound (EUS)-guided drainage of PFC with placement of an AXIOS stent. The lesions were accessed via transgastric (n = 7), transesophageal (n = 1), and transduodenal (n = 1) by using a novel access device (NAVIX) in six cases or a 19-G needle in three...
April 2013: Surgical Endoscopy
K F Binmoeller, J Shah
BACKGROUND AND STUDY AIMS: Tubular stents have been used to accomplish endoscopic transluminal drainage, but do not impart lumen-to-lumen anchorage. We evaluated a novel lumen-apposing stent designed for enteric drainage of nonadherent lumens. MATERIAL AND METHODS: Ex vivo benchtop testing was performed to quantify various physical and performance metrics of the stent (Axios). A simulator was developed to test the stent deployment through an echoendoscope. Survival experiments were performed on four pigs...
April 2011: Endoscopy
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