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https://www.readbyqxmd.com/read/29149636/examining-characteristics-associated-with-quitting-smoking-during-pregnancy-and-relapse-postpartum
#1
Farnaaz Kia, Nicole Tosun, Samantha Carlson, Sharon Allen
INTRODUCTION: Smoking during pregnancy is a significant public health concern that can cause adverse health outcomes for both the mother and fetus. Studies have shown only 40% of women quit smoking during pregnancy, with more than half relapsing within 6months, and up to 90% relapsing within one year. This study investigates differences in demographics and smoking-related symptomatology between pregnant smokers and pregnant quitters, as well as factors associated with postpartum relapse...
November 10, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29148066/predicting-the-use-of-corporal-punishment-child-aggression-parent-religiosity-and-the-bdnf-gene
#2
Reut Avinun, Maayan Davidov, David Mankuta, Ariel Knafo-Noam
Corporal punishment (CP) has been associated with deleterious child outcomes, highlighting the importance of understanding its underpinnings. Although several factors have been linked with parents' CP use, genetic influences on CP have rarely been studied, and an integrative view examining the interplay between different predictors of CP is missing. We focused on the separate and joint effects of religiosity, child aggression, parent's gender, and a valine (Val) to methionine (Met) substitution in the brain-derived neurotrophic factor (BDNF) gene...
November 17, 2017: Aggressive Behavior
https://www.readbyqxmd.com/read/29146655/qualitative-evaluation-of-a-deferred-consent-process-in-paediatric-emergency-research-a-predict-study
#3
Jeremy Furyk, Kristin McBain-Rigg, Kerrianne Watt, Theophilus I Emeto, Richard C Franklin, Donna Franklin, Andreas Schibler, Stuart R Dalziel, Franz E Babl, Catherine Wilson, Natalie Phillips, Robin Ray
BACKGROUND: A challenge of conducting research in critically ill children is that the therapeutic window for the intervention may be too short to seek informed consent prior to enrolment. In specific circumstances, most international ethical guidelines allow for children to be enrolled in research with informed consent obtained later, termed deferred consent (DC) or retrospective consent. There is a paucity of data on the attitudes of parents to this method of enrolment in paediatric emergency research...
November 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29144396/salivary-oxytocin-concentration-changes-during-a-group-drumming-intervention-for-maltreated-school-children
#4
Teruko Yuhi, Hiroaki Kyuta, Hisa-Aki Mori, Chihiro Murakami, Kazumi Furuhara, Mari Okuno, Masaki Takahashi, Daikei Fuji, Haruhiro Higashida
Many emotionally-disturbed children who have been maltreated and are legally separated from their parents or primary caregivers live in group homes and receive compulsory education. Such institutions provide various special intervention programs. Taiko-ensou, a Japanese style of group drumming, is one such program because playing drums in a group may improve children's emotional well-being. However, evidence for its efficacy has not been well established at the biological level. In this study, we measured salivary levels of oxytocin (OT), a neuropeptide associated with social memory and communication, in three conditions (recital, practice, and free sessions) in four classes of school-aged children...
November 16, 2017: Brain Sciences
https://www.readbyqxmd.com/read/29143890/paternal-anxiety-in-relation-to-toddler-anxiety-the-mediating-role-of-maternal-behavior
#5
Robert C Gibler, Anne E Kalomiris, Elizabeth J Kiel
Despite robust investigations examining the impact of maternal anxiety and parenting behaviors and child anxiety risk, less is understood about the impact of paternal anxiety and parenting behaviors on child anxiety risk, particularly within the broader family context. An Actor Partner Interdependence Model (APIM) was used to examine whether paternal anxiety longitudinally predicted child anxiety risk indirectly through maternal and paternal parenting behaviors, while controlling for maternal anxiety. Both fathers and mothers of 12- to 30-month-olds (n = 94) provided self-report of their anxiety and parenting behaviors...
November 16, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/29143602/molecular-and-agro-morphological-characterization-of-ancient-wheat-landraces-of-turkey
#6
Kahraman Gurcan, Fatih Demirel, Mehmet Tekin, Serap Demirel, Taner Akar
BACKGROUND: Turkey is one of the important gene centers for many crop species. In this research, some ancient wheats such as tetraploid and diploid hulled wheats together with hexaploid tir wheats (Triticum aestivum ssp. leucospermum Korn.) landraces mainly adapted to harsh winter conditions of Eastern Anatolian region of Turkey were characterized at agro-morphological and molecular level. Totally 50 hulled wheat population from Kastamonu, Konya and Kayseri provinces and 15 tir wheats from Kars provinces of Turkey were in-situ collected for characterization in 2013...
November 14, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/29143567/couple-relationship-quality-and-offspring-attachment-security-a-systematic-review-with-meta-analysis
#7
Evelyn S Tan, Jennifer E McIntosh, Emily J Kothe, Jessica E Opie, Craig A Olsson
This paper provides a meta-analytic examination of strength and direction of association between parents' couple relationship quality and early childhood attachment security (5 years and under). A comprehensive search of four EBSCOhost databases, Informit, Web of Science, and grey literature yielded 24 studies meeting eligibility criteria. Heterogeneity of the couple quality construct and measurement was marked. To disaggregate potentially differentially acting factors, we grouped homogeneous studies, creating two predictor variables defined as "positive dyadic adjustment" and "inter-parental conflict"...
November 16, 2017: Attachment & Human Development
https://www.readbyqxmd.com/read/29143539/psychiatric-care-of-children-with-autism-spectrum-disorder-what-do-their-siblings-think-about-it-a-qualitative-study
#8
Jordan Sibeoni, Louise Chambon, Noel Pommepuy, Clementine Rappaport, Anne Revah-Levy
The expectations and role of families in the care of children with autism spectrum disorder are increasingly important. Nonetheless, no study has thus far explored the perspectives of siblings about the care received by a brother or sister with this disorder. The objective of this study was to fill this gap in the literature. This multicentre qualitative study took place in France, where we conducted semi-structured interviews with adolescents who were older siblings of children receiving care in a day hospital for an autism spectrum disorder...
November 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29140412/alcohol-consumption-and-lung-cancer-risk-in-never-smokers-a-pooled-analysis-of-case-control-studies
#9
José A García Lavandeira, Alberto Ruano-Ravina, Karl T Kelsey, María Torres-Durán, Isaura Parente-Lamelas, Virginia Leiro-Fernández, Maruxa Zapata, José Abal-Arca, Iria Vidal-García, Carmen Montero-Martínez, Margarita Amenedo, Olalla Castro-Añón, Antonio Golpe-Gómez, Rosirys Guzmán-Taveras, Cristina Martínez, Mariano Provencio, María J Mejuto-Martí, Silvia García-García, Alberto Fernández-Villar, María Piñeiro, Juan M Barros-Dios
Background: Lung cancer is the deadliest cancer in developed countries but the etiology of lung cancer risk in never smokers (LCRINS) is largely unknown. We aim to assess the effects of alcohol consumption, in its different forms, on LCRINS. Methods: We pooled six multi-center case-control studies developed in the northwest of Spain. Cases and controls groups were composed of never smokers. We selected incident cases with anatomopathologically confirmed lung cancer diagnoses...
November 13, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/29139565/leukocyte-adhesion-defect-i-rare-primary-immune-deficiency
#10
Nitesh Tewari, Vijay Prakash Mathur, Vikender Singh Yadav, Prabhat Chaudhari
Leukocyte adhesion defect I is a rare disorder (1:1,000,000) caused by diminished expression of CD-18 β2 integrins on leukocytes leading to abnormal adhesion, migration, and chemotaxis. Clinical manifestations include delayed separation of umbilical cord, omphalitis, recurrent severe infections, impaired wound healing, persistent oral ulcers, and severe periodontitis in primary and permanent dentition. A 5-year-old girl, second-born child to parents with consanguinity, presented with pain and mobility of lower teeth...
November 15, 2017: Special Care in Dentistry
https://www.readbyqxmd.com/read/29138497/rapid-purification-of-human-bispecific-antibodies-via-selective-modulation-of-protein-a-binding
#11
Adam Zwolak, Catherine N Leettola, Susan H Tam, Dennis R Goulet, Mehabaw G Derebe, Jose R Pardinas, Songmao Zheng, Rose Decker, Eva Emmell, Mark L Chiu
Methods to rapidly generate high quality bispecific antibodies (BsAb) having normal half-lives are critical for therapeutic programs. Here, we identify 3 mutations (T307P, L309Q, and Q311R or "TLQ") in the Fc region of human IgG1 which disrupt interaction with protein A while enhancing interaction with FcRn. The mutations are shown to incrementally alter the pH at which a mAb elutes from protein A affinity resin. A BsAb comprised of a TLQ mutant and a wild-type IgG1 can be efficiently separated from contaminating parental mAbs by differential protein A elution starting from either a) purified parental mAbs, b) in-supernatant crossed parental mAbs, or c) co-transfected mAbs...
November 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29136483/fitness-sleep-disordered-breathing-symptoms-of-depression-and-cognition-in-inactive-overweight-children-mediation-models
#12
Monika M K Stojek, Amanda K Montoya, Christopher F Drescher, Andrew Newberry, Zain Sultan, Celestine F Williams, Norman K Pollock, Catherine L Davis
OBJECTIVES: We used mediation models to examine the mechanisms underlying the relationships among physical fitness, sleep-disordered breathing (SDB), symptoms of depression, and cognitive functioning. METHODS: We conducted a cross-sectional secondary analysis of the cohorts involved in the 2003-2006 project PLAY (a trial of the effects of aerobic exercise on health and cognition) and the 2008-2011 SMART study (a trial of the effects of exercise on cognition). A total of 397 inactive overweight children aged 7-11 received a fitness test, standardized cognitive test (Cognitive Assessment System, yielding Planning, Attention, Simultaneous, Successive, and Full Scale scores), and depression questionnaire...
November 2017: Public Health Reports
https://www.readbyqxmd.com/read/29122994/childhood-psychosocial-adversity-and-female-reproductive-timing-a-cohort-study-of-the-alspac-mothers
#13
Maria C Magnus, Emma L Anderson, Laura D Howe, Carol J Joinson, Ian S Penton-Voak, Abigail Fraser
BACKGROUND: Previous studies of childhood psychosocial adversity and age at menarche mostly evaluated single or a few measures of adversity, and therefore could not quantify total psychosocial adversity. Limited knowledge is currently available regarding childhood psychosocial adversity in relation to age at menopause and reproductive lifespan. METHODS: We examined the associations of total and specific components of childhood psychosocial adversity with age at menarche (n=8984), age at menopause (n=945), and length of reproductive lifespan (n=841), in mothers participating in the Avon Longitudinal Study of Parents and Children...
November 9, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29119714/cross-cultural-adaptation-and-validation-of-the-spanish-version-of-the-paediatric-throat-disorders-outcome-test-t-14
#14
Francisco Larrosa, Laura Samara, Eduard Esteller, Maria J Dura, Yolanda Escamilla, Anna Alberti, Rosa Rosell, Claire Hopkins
OBJECTIVES: The Paediatric Throat Disorders Outcome Test (T-14) is a disease-specific questionnaire that parents are requested to complete; it aims to assess the quality of life related to tonsil and adenoid disease or its treatment in children with throat disorders. The aim of this study was to validate the Spanish adaptation of the T-14, thus allowing comparison across studies and facilitating international multicentre projects. DESIGN, SETTING AND PARTICIPANTS: This was a multicentre prospective instrument validation study...
November 9, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29119460/personal-genomic-testing-genetic-inheritance-and-uncertainty
#15
Paul H Mason
The case outlined below is the basis for the In That Case section of the "Ethics and Epistemology of Big Data" symposium. Jordan receives reports from two separate personal genomic tests that provide intriguing data about ancestry and worrying but ambiguous data about the potential risk of developing Alzheimer's disease. What began as a personal curiosity about genetic inheritance turns into an alarming situation of medical uncertainty. Questions about Jordan's family tree are overshadowed by even more questions about Alzheimer's disease and healthy ageing...
November 8, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/29119256/gas-chromatographic-retention-behavior-of-polycyclic-aromatic-hydrocarbons-pahs-and-alkyl-substituted-pahs-on-two-stationary-phases-of-different-selectivity
#16
Federica Nalin, Lane C Sander, Walter B Wilson, Stephen A Wise
Retention indices (I) for 45 polycyclic aromatic hydrocarbons (PAHs) and 63 methyl-substituted PAHs were determined by gas chromatography - mass spectrometry (GC-MS) using two different stationary phases: a Rxi-PAH phase (a "higher phenyl-content stationary phase") and a 50% (mole fraction) liquid crystalline dimethylpolysiloxane phase. Retention data were obtained for parent PAHs from molecular mass (MM) 128 g/mol (naphthalene) to 328 g/mol (benzo[c]picene) and for 12 sets of methyl-PAHs (methylfluorenes, methylanthracenes, methylphenanthrenes, methylfluoranthenes, methylpyrenes, methylbenz[a]anthracenes, methylbenzo[c]phenanthrenes, methylchrysenes, methyltriphenylenes, methylbenzo[a]pyrenes, methylperylenes, and methylpicenes)...
November 8, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29119001/a-swedish-national-adoption-study-of-risk-of-irritable-bowel-syndrome-ibs
#17
Rasmus Waehrens, Bengt Zöller, Jan Sundquist, Kristina Sundquist, MirNabi Pirouzifard
Objectives: Irritable bowel syndrome (IBS) clusters in families, but the familial risk of IBS has not been determined in adoptees. Studying adoptees and their biological and adoptive parents is a strong study design for separating genetic from environmental causes of familial clustering. This nationwide study aimed to separate the biological (genetic) and familial environmental contribution to the familial transmission of IBS. Methods: We performed a family study for Swedish-born adoptees born from 1951 until 1995, and their biological and adoptive parents...
2017: BMJ Open Gastroenterology
https://www.readbyqxmd.com/read/29118775/accumulation-profiles-of-embryonic-salt-soluble-proteins-in-maize-hybrids-and-parental-lines-indicate-matroclinous-inheritance-a-proteomic-analysis
#18
Fen Ning, Xiaolin Wu, Hang Zhang, Zhaokun Wu, Liangjie Niu, Hao Yang, Wei Wang
Maize is one of the most widely cultivated crops. It accumulates a large quantity of seed storage proteins, which are important for seed development and germination, and contribute to the nutritional quality of seeds. Based on solubility, the storage proteins are divided into albumins (water-soluble), globulins (salt-soluble), prolamins (alcohol-soluble), and glutelins (acid- or alkali-soluble). Maize hybrids are cultivated due to the superior performance of F1 hybrids than that of their parents, a phenomenon known as heterosis...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29114859/antiepileptic-drug-behavioral-side-effects-and-baseline-hyperactivity-in-children-and-adolescents-with-new-onset-epilepsy
#19
Shanna M Guilfoyle, Katherine Follansbee-Junger, Aimee W Smith, Angela Combs, Shannon Ollier, Brooke Hater, Avani C Modi
OBJECTIVE: To examine baseline psychological functioning and antiepileptic drug (AED) behavioral side effects in new onset epilepsy and determine, by age, whether baseline psychological functioning predicts AED behavioral side effects 1 month following AED initiation. METHODS: A retrospective chart review was conducted between July 2011 and December 2014 that included youths with new onset epilepsy. As part of routine interdisciplinary care, caregivers completed the Behavior Assessment System for Children, 2nd Edition: Parent Rating Scale to report on baseline psychological functioning at the diagnostic visit and the Pediatric Epilepsy Side Effects Questionnaire to identify AED behavioral side effects at the 1-month follow-up clinic visit following AED initiation...
November 8, 2017: Epilepsia
https://www.readbyqxmd.com/read/29112839/environmental-fate-of-amine-oxide-using-measured-and-predicted-values-to-determine-aquatic-exposure
#20
Kathleen McDonough, Nina Itrich, Jennifer Menzies, Kenneth Casteel, Scott Belanger, Kenneth Wehmeyer
Amine oxide (AO) surfactants are used widely in North American household detergents resulting in >44,000mtons disposed down the drain annually. Due to AOs substantial down the drain disposal volume, wide dispersive use, and high aquatic toxicity, there is a need to evaluate ecological exposure and corresponding risk. This study refined the current knowledge regarding the fate of AO disposed down the drain through laboratory simulation studies to evaluate biodegradation in the sewer and during activated sludge wastewater treatment...
November 4, 2017: Science of the Total Environment
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