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https://www.readbyqxmd.com/read/28628955/recovering-the-father-in-mind-and-flesh-history-triadic-functioning-and-developmental-implications
#1
Michael J Diamond
This paper aims to restore the father and paternal function to their rightful place alongside the mother and maternity in order to counter the prevailing matricentric, dyadic bias in psychoanalytic theory and technique. The author contends that both the symbolic and the actual, flesh-and-blood father are necessary to optimize his child's development. The paternal function inevitably operates in a triadic matrix; thirdness is always psychically in existence-with the father ever present in the mother's unconscious mind-and the paternal third is necessary to open up symbolic space...
April 2017: Psychoanalytic Quarterly
https://www.readbyqxmd.com/read/28611664/2-pentadecyl-2-oxazoline-the-oxazoline-of-pea-modulates-carrageenan-induced-acute-inflammation
#2
Stefania Petrosino, Michela Campolo, Daniela Impellizzeri, Irene Paterniti, Marco Allarà, Enrico Gugliandolo, Ramona D'Amico, Rosalba Siracusa, Marika Cordaro, Emanuela Esposito, Vincenzo Di Marzo, Salvatore Cuzzocrea
N-acylethanolamines (NAEs) involve a family of lipid molecules existent in animal and plant, with N-palmitoylethanolamide (PEA) that arouses great attention owing to its anti-inflammatory, analgesic and neuroprotective activities. Because PEA is produced on demand and exerts pleiotropic effects, the modulation of specific amidases for NAEs (and in particular NAE-hydrolyzing acid amidase NAAA, which is more selective for PEA) could be a condition to preserve its levels. Here we investigate the effect of 2-Pentadecyl-2-oxazoline (PEA-OXA) the oxazoline of PEA, on human recombinant NAAA in vitro and in an established model of Carrageenan (CAR)-induced rat paw inflammation...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28605149/increase-in-multiple-paternity-across-the-reproductive-lifespan-in-a-sperm-storing-hermaphroditic-freshwater-snail
#3
Anja Bürkli, Jukka Jokela
Polyandry is a common phenomenon and challenges the traditional view of stronger sexual selection in males than in females. In simultaneous hermaphrodites, the physical proximity of both sex functions was long thought to preclude the operation of sexual selection. Laboratory studies suggest that multiple mating and polyandry in hermaphrodites may actually be common, but data from natural populations are sparse. We therefore estimated the rate of multiple paternity and its seasonal variability in the annual, sperm-storing, simultaneously hermaphroditic freshwater snail Radix balthica for the entire duration of the reproductive lifespan...
June 12, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28561420/cab4b-the-first-human-platelet-antigen-carried-by-gpix-discovered-in-a-context-of-severe-neonatal-thrombocytopenia
#4
V Jallu, T Beranger, F Bianchi, C Casale, C Chenet, N Ferre, S Philippe, J Quesne, C Martageix, R Petermann
BACKGROUND: After 3 miscarriages, a 39-year-old woman gave birth at 1 year interval to 2 severely thrombocytopenic neonates (4 and 33 G/L) with intracranial haemorrhages. Transfusion of platelets concentrates corrected thrombocytopenias. The outcome was favourable for the 1(st) child but the second one died 10 days after caesarean delivery (31 WG + 6 days). METHODS: Serological studies were performed using MAIPA and flow cytometry techniques. Human platelet antigens (HPA) genotyping was done by using the BioArray HPA BeadChip and PCR-SSP techniques...
May 31, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28557020/first-time-fathers-postnatal-experiences-and-support-needs-a-descriptive-qualitative-study
#5
Shefaly Shorey, Cindy-Lee Dennis, Shiho Bridge, Yap Seng Chong, Eleanor Holroyd, Hong-Gu He
AIM: To explore first-time fathers' postnatal experiences and support needs in the early postpartum period. BACKGROUND: The postnatal period is a stressful transition period for new fathers. It is imperative to understand their needs and experiences to provide appropriate support for them. The majority of previous studies were based in Western countries and explored fathers' needs during pregnancy and childbirth, with few studies conducted in the postnatal period...
May 30, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28555302/respecting-the-dignity-of-children-with-disabilities-in-clinical-practice
#6
Adam Cureton, Anita Silvers
Prevailing philosophies about parental and other caregiver responsibilities toward children tend to be protectionist, grounded in informed benevolence in a way that countenances rather than circumvents intrusive paternalism. And among the kinds of children an adult might be called upon to parent or otherwise care for, children with disabilities figure among those for whom the strongest and snuggest shielding is supposed be deployed. In this article, we examine whether this equation of securing well-being with sheltering by protective parents and other care-givers should unreflectively be adopted for disabled children...
May 29, 2017: HEC Forum: An Interdisciplinary Journal on Hospitals' Ethical and Legal Issues
https://www.readbyqxmd.com/read/28492708/shadows-of-doubt-the-uneasy-incorporation-of-identification-science-into-legal-determination-of-paternity-in-brazil
#7
Sueann Caulfield, Alexandra Minna Stern
The arrival of DNA paternity testing in the 1980s was met with great enthusiasm in the Brazilian courts. Yet, over the past two decades, Brazilian legal doctrine and jurisprudence have increasingly rejected DNA proof as the sine qua non for paternity cases. Instead, DNA paternity testing has generated mountains of litigation, as biological proof has been challenged by the argument that paternity is primarily "socio-affective". Leading family law specialists describe this new conception of paternity as an outcome of the "revolutionary" provisions of the 1988 Constitution, which recognizes the "pluralism" of family forms in modern society and guarantees equal family rights for all children...
May 8, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28489339/de-novo-igf2-mutation-on-the-paternal-allele-in-a-patient-with-silver-russell-syndrome-and-ectrodactyly
#8
Kaori Yamoto, Hirotomo Saitsu, Norio Nakagawa, Hisakazu Nakajima, Tatsuji Hasegawa, Yasuko Fujisawa, Masayo Kagami, Maki Fukami, Tsutomu Ogata
Although paternally expressed IGF2 is known to play a critical role in placental and body growth, only a single mutation has been found in IGF2. We identified, through whole-exome sequencing, a de novo IGF2 indel mutation leading to frameshift (NM_000612.5:c.110_117delinsAGGTAA, p.(Leu37Glnfs*31)) in a patient with Silver-Russell syndrome, ectrodactyly, undermasculinized genitalia, developmental delay, and placental hypoplasia. Furthermore, we demonstrated that the mutation resided on the paternal allele by sequencing the long PCR product harboring the mutation- and methylation-sensitive SmaI and SalI sites before and after SmaI/SalI digestion...
May 10, 2017: Human Mutation
https://www.readbyqxmd.com/read/28450065/social-inequalities-and-dental-caries-in-six-year-old-children-from-the-netherlands
#9
Justin T van der Tas, Lea Kragt, Marlies E C Elfrink, Loes C M Bertens, Vincent W V Jaddoe, Henriëtte A Moll, Edwin M Ongkosuwito, Eppo B Wolvius
OBJECTIVES: The purpose of our study was to investigate the association of different socioeconomic and sociodemographic factors with dental caries in six-year-old children. Furthermore, we applied a district based approach to explore the distribution of dental caries among districts of low and high socioeconomic position (SEP). METHODS: In our cross-sectional study 5189 six-year-olds were included. This study was embedded in a prospective population-based birth cohort study in Rotterdam, the Netherlands, the Generation R Study...
April 24, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28437562/no-postcopulatory-selection-against-mhc-homozygous-offspring-evidence-from-a-pedigreed-captive-rhesus-macaque-colony
#10
E H M Sterck, R E Bontrop, N de Groot, A J M de Vos-Rouweler, G G M Doxiadis
The heterozygosity status of polymorphic elements of the immune system, such as the major histocompatibility complex (MHC), is known to increase the potential to cope with a wider variety of pathogens. Pre- and postcopulatory processes may regulate MHC heterozygosity. In a population where mating occurs among individuals that share identical MHC haplotypes, postcopulatory selection may disfavour homozygous offspring or ones with two MHC haplotypes identical to its mother. We tested these ideas by determining the incidence of MHC-heterozygous and MHC-homozygous individuals in a pedigreed, partially consanguineous captive rhesus monkey colony...
April 24, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28407234/mediterranean-diet-decreases-adolescent-waist-circumference
#11
Flora Bacopoulou, Georgios Landis, Anastasios Rentoumis, Artemis Tsitsika, Vasiliki Efthymiou
BACKGROUND: To explore the effects of a multicomponent-multilevel school-based educational intervention on the nutritional habits and abdominal obesity indices of a representative adolescent sample. MATERIALS AND METHODS: A representative sample of 1610 adolescents aged 12-17 years in 23 public high schools of three municipalities in the Attica region in Greece participated in a programme funded by the European Union (August 2013-August 2014). Participants underwent dietary assessment with the use of the Mediterranean Diet Quality Index in children and adolescents (KIDMED), blood pressure (BP) assessment and screening for general and abdominal obesity by measuring body mass index, waist circumference (WC) and waist-to-height ratio (WHtR), at baseline and following a 6-month school-based intervention...
April 13, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28401836/insensitive-parenting-may-accelerate-the-development-of-the-amygdala-medial-prefrontal-cortex-circuit
#12
Sandra Thijssen, Ryan L Muetzel, Marian J Bakermans-Kranenburg, Vincent W V Jaddoe, Henning Tiemeier, Frank C Verhulst, Tonya White, Marinus H Van Ijzendoorn
This study examined whether the association between age and amygdala-medial prefrontal cortex (mPFC) connectivity in typically developing 6- to 10-year-old children is correlated with parental care. Resting-state functional magnetic resonance imaging scans were acquired from 124 children of the Generation R Study who at 4 years old had been observed interacting with their parents to assess maternal and paternal sensitivity. Amygdala functional connectivity was assessed using a general linear model with the amygdalae time series as explanatory variables...
May 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28394407/novel-case-of-paternal-paracentric-inversion-causing-partial-trisomy-13-and-review-of-the-literature
#13
Chad Douglas, Stephen A Smith, Luis Rohena
Partial trisomies have often been reported secondary to inversion mutations. These occurrences are most frequently associated with pericentric inversions. In this report, we describe the first documented case of partial trisomy 13 secondary to a parental paracentric inversion, in this case a paternal paracentric 13q inversion. Our Patient exhibits a variety of clinical findings including global developmental delay with intellectual disability, sensorineural hearing loss, bilateral congenital polar cataracts with associated foveal and optic nerve hypoplasia, right retinal detachment, atrial septal defect, absence of corpus callosum, celiac disease, microcephaly, as well as other dysmorphic features...
June 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28387056/effects-of-ovarian-fluid-and-genetic-differences-on-sperm-performance-and-fertilization-success-of-alternative-reproductive-tactics-in-chinook-salmon
#14
S J Lehnert, I A E Butts, E W Flannery, K M Peters, D D Heath, T E Pitcher
In many species, sperm velocity affects variation in the outcome of male competitive fertilization success. In fishes, ovarian fluid (OF) released with the eggs can increase male sperm velocity and potentially facilitate cryptic female choice for males of specific phenotypes and/or genotypes. Therefore, to investigate the effect of OF on fertilization success, we measured sperm velocity and conducted in vitro competitive fertilizations with paired Chinook salmon (Oncorhynchus tshawytscha) males representing two alternative reproductive tactics, jacks (small sneaker males) and hooknoses (large guarding males), in the presence of river water alone and OF mixed with river water...
April 7, 2017: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/28386961/adult-dietary-protein-has-age-and-context-dependent-effects-on-male-post-copulatory-performance
#15
Erin L Macartney, Angela J Crean, Russell Bonduriansky
The highly-conserved effect of dietary protein restriction on life-span and ageing is observed in both sexes and across a vast range of taxa. This extension of life-span is frequently accompanied by a reduction in female fecundity and it has been hypothesised that individuals may reallocate resources away from reproduction and into somatic maintenance. However, effects of dietary protein restriction on male reproduction are less consistent, suggesting that these effects may depend on other environmental parameters...
April 7, 2017: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/28371365/a-memory-b-cell-crossmatch-assay-for-quantification-of-donor-specific-memory-b-cells-in-the-peripheral-blood-of-hla-immunized-individuals
#16
G E Karahan, Y J H de Vaal, J Krop, C Wehmeier, D L Roelen, F H J Claas, S Heidt
Humoral responses against mismatched donor HLA are routinely measured as serum HLA antibodies, which are mainly produced by bone marrow-residing plasma cells. Individuals with a history of alloimmunization but lacking serum antibodies may harbor circulating dormant memory B cells, which may rapidly become plasma cells on antigen reencounter. Currently available methods to detect HLA-specific memory B cells are scarce and insufficient in quantifying the complete donor-specific memory B cell response due to their dependence on synthetic HLA molecules...
March 30, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28370951/multivariate-genetic-architecture-of-the-anolis-dewlap-reveals-both-shared-and-sex-specific-features-of-a-sexually-dimorphic-ornament
#17
R M Cox, R A Costello, B E Camber, J W McGlothlin
Darwin viewed the ornamentation of females as an indirect consequence of sexual selection on males and the transmission of male phenotypes to females via the 'laws of inheritance'. Although a number of studies have supported this view by demonstrating substantial between-sex genetic covariance for ornament expression, the majority of this work has focused on avian plumage. Moreover, few studies have considered the genetic basis of ornaments from a multivariate perspective, which may be crucial for understanding the evolution of sex differences in general, and of complex ornaments in particular...
March 31, 2017: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/28370606/sports-activities-in-preschool-children-differed-between-those-born-to%C3%A2-immigrants-and-native-italians
#18
Luciana Zaccagni, Stefania Toselli, Francesca Celenza, Augusta Albertini, Emanuela Gualdi-Russo
AIM: Despite the health benefits of physical activity in early childhood, little is known about sports practices in preschool children with different ethnic origins. The aim of this study was to investigate the sport activity patterns in native and immigrant children in northern Italy. The influence of some child and family determinants on the child's practice of club-organised sport was analysed to plan interventions. METHODS: The study group comprised 2682 preschool children (49...
March 31, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28370584/benefits-of-polyandry-molecular-evidence-from-field-caught-dung-beetles
#19
Erin L McCullough, Bruno A Buzatto, Leigh W Simmons
When females mate with multiple males, they set the stage for postcopulatory sexual selection via sperm competition and/or cryptic female choice. Surprisingly little is known about the rates of multiple mating by females in the wild, despite the importance of this information in understanding the potential for postcopulatory sexual selection to drive the evolution of reproductive behaviour, morphology and physiology. Dung beetles in the genus Onthophagus have become a laboratory model for studying pre- and postcopulatory sexual selection, yet we still lack information about the reproductive behaviour of female dung beetles in natural populations...
March 30, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28369868/pre-and-postcopulatory-sexual-selection-favor-aggressive-young-males-in-polyandrous-groups-of-red-junglefowl
#20
Grant C McDonald, Lewis G Spurgin, Eleanor A Fairfield, David S Richardson, Tommaso Pizzari
A challenge in evolutionary biology is to understand the operation of sexual selection on males in polyandrous groups, where sexual selection occurs before and after mating. Here, we combine fine-grained behavioral information (>41,000 interactions) with molecular parentage data to study sexual selection in replicated, age-structured groups of polyandrous red junglefowl, Gallus gallus. Male reproductive success was determined by the number of females mated (precopulatory sexual selection) and his paternity share, which was driven by the polyandry of his female partners (postcopulatory sexual selection)...
June 2017: Evolution; International Journal of Organic Evolution
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