keyword
MENU ▼
Read by QxMD icon Read
search

Hong, Chang-Ki

keyword
https://www.readbyqxmd.com/read/28730614/synchrotron-tomographic-images-from-human-lung-adenocarcinoma-three-dimensional-reconstruction-and-histologic-correlations
#1
Eunjue Yi, Sung-Mi Han, Ji-Eun Chang, Hong-Tae Kim, Jong-Ki Kim, Seung-Jun Seo, Jin-Haeng Chung, Sanghoon Jheon
High-resolution tomographic images using synchrotron X-rays are expected to provide detailed reflection of microstructures, thereby allowing for the examination of histologic structures without destruction of the specimen. This study aims to evaluate the synchrotron tomographic images of mixed ground-glass opacity excised on 5-mm sections in comparison to pathologic examination. The Institutional Review Board of our institute approved this retrospective study, and written informed consent was obtained from each patient whose lung tissue would be used...
July 21, 2017: Microscopy Research and Technique
https://www.readbyqxmd.com/read/28729461/morphology-of-the-archaellar-motor-and-associated-cytoplasmic-cone-in-thermococcus-kodakaraensis
#2
Ariane Briegel, Catherine M Oikonomou, Yi-Wei Chang, Andreas Kjær, Audrey N Huang, Ki Woo Kim, Debnath Ghosal, Hong H Nguyen, Dorothy Kenny, Rachel R Ogorzalek Loo, Robert P Gunsalus, Grant J Jensen
Archaeal swimming motility is driven by archaella: rotary motors attached to long extracellular filaments. The structure of these motors, and particularly how they are anchored in the absence of a peptidoglycan cell wall, is unknown. Here, we use electron cryotomography to visualize the archaellar basal body in vivo in Thermococcus kodakaraensis KOD1. Compared to the homologous bacterial type IV pilus (T4P), we observe structural similarities as well as several unique features. While the position of the cytoplasmic ATPase appears conserved, it is not braced by linkages that extend upward through the cell envelope as in the T4P, but rather by cytoplasmic components that attach it to a large conical frustum up to 500 nm in diameter at its base...
July 19, 2017: EMBO Reports
https://www.readbyqxmd.com/read/28691907/prognosis-of-deferred-non-culprit-lesions-according-to-fractional-flow-reserve-in-patients-with-acute-coronary-syndrome
#3
Joo Myung Lee, Ki Hong Choi, Bon-Kwon Koo, Eun-Seok Shin, Chang-Wook Nam, Joon-Hyung Doh, Doyeon Hwang, Jonghanne Park, Jinlong Zhang, Hong-Seok Lim, Myeong-Ho Yoon, Seung-Jea Tahk
AIMS: There are limited data on the prognosis of deferred non-culprit lesions in patients with acute coronary syndrome (ACS) based on fractional flow reserve (FFR). We investigated the prognosis of deferred non-culprit lesions in ACS patients, compared with deferred lesions in patients with stable coronary artery disease (SCAD), on the basis of FFR. METHODS AND RESULTS: The clinical outcomes of 449 non-culprit lesions (301 patients with ACS) were compared with 2,484 lesions (1,295 patients with SCAD) in which revascularization was deferred on the basis of a high FFR (>0...
July 11, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28684150/sandwich-technique-using-fibrin-coated-collagen-fleece-for-sellar-reconstruction-in-large-dural-defects-during-transsphenoidal-surgery
#4
Jaeyoung So, Hunho Park, Kyeong-Soo Sung, Kyu Sung Lee, Chang-Ki Hong
PURPOSE: Various surgical methods to prevent intraoperative and postoperative cerebrospinal fluid (CSF) leaks during transsphenoidal approach (TSA) surgeries have been reported, but surgical techniques to address large dural defects have been less thoroughly investigated in the literature. The authors retrospectively evaluated the usefulness of the sandwich technique using fibrin-coated collagen fleece (TachoSil) to prevent intraoperative CSF leakage from large dural defects in TSA surgery...
July 3, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28682902/long-term-outcomes-of-concomitant-chemoradiotherapy-with-temozolomide-for-newly-diagnosed-glioblastoma-patients-a-single-center-analysis
#5
Tae Hoon Roh, Hun Ho Park, Seok-Gu Kang, Ju Hyung Moon, Eui Hyun Kim, Chang-Ki Hong, Sung Soo Ahn, Hye Jin Choi, Jaeho Cho, Se Hoon Kim, Seung Koo Lee, Dong Seok Kim, Sun Ho Kim, Chang-Ok Suh, Kyu Sung Lee, Jong Hee Chang
The present study analyzed outcomes of surgery followed by concomitant chemoradiotherapy (CCRT) with temozolomide (TMZ) in patients with newly diagnosed glioblastoma (GBM) at a single institution. Outcomes were retrospectively reviewed in 252 consecutive patients with newly diagnosed GBM who underwent surgery followed by CCRT with TMZ at the authors' institution between 2005 and 2013. At initial operation, 126 (50.0%), 55 (21.8%), 45 (17.9%), and 26 (10.3%) patients underwent gross total resection (GTR), subtotal resection, partial resection (PR), and biopsy, respectively...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28671770/clinical-outcomes-of-patients-with-resectable-pancreatic-acinar-cell-carcinoma
#6
Seyoung Seo, Changhoon Yoo, Kyu-Pyo Kim, Baek-Yeol Ryoo, Heung-Moon Chang, Seung-Mo Hong, Jae Hoon Lee, Ki Byung Song, Dae Wook Hwang, Ki-Hun Kim, Shin Hwang, Song Cheol Kim
AIM: With rarity of disease, the post-resection clinical course of localized pancreatic acinar cell carcinoma (ACC) is largely unknown. Therefore, we analyzed the outcomes of patients with localized pancreatic ACCs who underwent surgical resection. METHODS: We retrospectively analyzed the outcomes of 20 patients with resectable pancreatic ACC who underwent surgery. RESULTS: Median age was 57 years and 16 were male. The ACCs were composed of 8 pure ACCs, 10 mixed acinar-neuroendocrine carcinomas, and 2 mixed acinar-ductal adenocarcinomas...
July 3, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28653247/post-traumatic-headache-in-patients-with-minimal-traumatic-intracranial-hemorrhage-after-traumatic-brain-injury-a-retrospective-matched-case-control-study
#7
Chang-Ki Hong, Yu Shik Shim, Sook Young Sim, Jin-Yang Joo, Min A Kwon, Yong Bae Kim, Joonho Chung
BACKGROUND: No evidence is available on the risks of neurologically asymptomatic minimal traumatic intracranial hemorrhage (mTIH) in patients with traumatic brain injury (TBI) for post-traumatic headache (PTH). The purpose of this study was to investigate whether mTIH in patients with TBI was associated with PTH and to evaluate its risk factors. METHODS: Between September 2009 and December 2014, 1484 patients with TBI were treated at our institution, 57 of whom had mTIH after TBI and were include in this study...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28653158/usefulness-of-mapping-biopsy-in-the-treatment-of-penoscrotal-extramammary-paget-s-disease
#8
Seong Oh Park, Jeong Hyun Ha, Ki Yong Hong, Hak Chang
BACKGROUND: Extramammary Paget's disease (EMPD) is a rare cutaneous malignancy; however, the standard treatment of EMPD has not been established. In this study, we applied mapping biopsy to penoscrotal EMPD and evaluated its effects. METHODS: A retrospective chart review was performed to determine the outcomes of patients with primary penoscrotal EMPD who underwent surgery at our institution between 2007 and 2014. Patients were divided into two groups (one group underwent mapping biopsy, while the other group did not), and the difference between the two groups was analyzed...
June 26, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28642210/rationale-and-design-for-a-randomized-comparison-of-efficacy-and-safety-between-aspirin-and-clopidogrel-in-atrial-fibrillation-patients-with-low-stroke-risk-cesac-af-trial
#9
Sang Min Park, Haemin Jeong, Mi-Hyang Jung, Kyung Soon Hong, Myeong-Ki Hong, Chang Seok Bang, Christopher Y Kim
BACKGROUND: Atrial fibrillation (AF) increases the risk of thromboembolic stroke. An oral anticoagulant should be administrated to prevent stroke in patients with moderate stroke risk (ie, CHA2DS2-VASc score>2). If the stroke risk is low (i.e. the score=1), however, antiplatelet agent such as aspirin is widely used. Aspirin can cause peptic ulcer disease (PUD) while its alternative, clopidogrel, theoretically does not. OBJECTIVE: To elucidate the efficacy and safety between aspirin and clopidogrel, a multicenter randomized controlled trial was designed in AF patients with low stroke risk...
June 19, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28639850/field-scale-electrolysis-ceramic-membrane-system-for-the-treatment-of-sewage-from-decentralized-small-communities
#10
Dong-Jin Son, Woo-Yeol Kim, Chan-Young Yun, Dae-Gun Kim, Duk Chang, Young Sunwoo, Ki-Ho Hong
The electrolysis process adopting copper electrodes and ceramic membrane with pore sizes of 0.1-0.2 μm were consisted to a system for the treatment of sewage from decentralized small communities. The system was operated under an HRT of 0.1 hour, voltage of 24 V, and TMP of 0.05 MPa. The system showed average removals of organics, nitrogen, phosphorus, and solids of up to 80%, 52%, 92%, and 100%, respectively. Removal of organics and nitrogen dramatically increased in proportion to increment of influent loading...
July 5, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28634823/a-nationwide-study-of-the-incidence-rate-of-herb-induced-liver-injury-in-korea
#11
Jung-Hyo Cho, Dal-Seok Oh, Sang-Hoon Hong, Heung Ko, Nam-Hun Lee, Sang-Eun Park, Chang-Woo Han, Seung-Mo Kim, Young-Chul Kim, Kang-San Kim, Chang-Won Choi, Seon-My Shin, Ki-Tae Kim, Hong-Sik Choi, Jang-Hoon Lee, Jun-Young Kim, Ji-Young Kang, Dong-Soo Lee, Yo-Chan Ahn, Chang-Gue Son
Discrepant incidence has been reported regarding the incidence of herb-induced liver injury (HILI). To address the growing worldwide concern of HILI, we evaluated the risk of HILI in a nationwide prospective study. Between April 2013 and January 2016, 1001 inpatients (360 males and 641 females) from 10 tertiary hospitals throughout South Korea were treated with herbal drugs and had their liver enzymes periodically measured. A total of six patients met the criteria for HILI with RUCAM scores ranging from 4 to 7...
June 20, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/28626049/dose-dependent-effect-of-statin-pretreatment-on-preventing-the-periprocedural-complications-of-carotid-artery-stenting
#12
Jeong-Ho Hong, Sung-Il Sohn, Jaehyuk Kwak, Joonsang Yoo, Hyuk Won Chang, O-Ki Kwon, Cheolkyu Jung, Inyoung Chung, Hee-Joon Bae, Ji Sung Lee, Moon-Ku Han
BACKGROUND AND PURPOSE: We investigated whether statin pretreatment can dose dependently reduce periprocedural complications in patients undergoing carotid artery stenting because of symptomatic carotid artery stenosis. METHODS: We enrolled a consecutive series of 397 symptomatic carotid artery stenosis (≥50% stenosis on conventional angiography) treated with carotid artery stenting at 2 tertiary university hospitals over a decade. Definition of periprocedural complications included any stroke, myocardial infarction, and death within 1 month after or during the procedure...
July 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28623761/the-added-value-of-the-csf-cleft-on-adc-in-distinguishing-extra-axial-from-intra-axial-tumors
#13
Junyoung Kim, Chang-Ki Hong, Sang Hyun Suh, Woo Sang Jung, Sung Jun Ahn
We investigated whether the CSF cleft sign on ADC maps is beneficial for differentiating extra-axial tumors from intra-axial tumors. Seventy-seven intracranial tumor patients were reviewed. Visual grades of CSF cleft sign on T2WI and ADC were compared. The diagnostic performance of CSF cleft sign using ADC plus T2WI was compared with that using T2WI alone. A CSF cleft was more easily visualized on ADC (P<0.01). The diagnostic performance of CSF cleft sign significantly increased in accuracy of 85.7 to 96...
April 27, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28621108/inhibitory-effects-of-flavonoids-from-spatholobus-suberectus-on-sortase-a-and-sortase-a-mediated-aggregation-of-streptococcus-mutans
#14
Wanki Park, Chan-Hong Ahn, Hyunjoo Cho, Chang-Kwon Kim, Jongheon Shin, Ki-Bong Oh
Seven flavonoids were isolated from Spatholobus suberectus via repetitive column chromatography and high-performance liquid chromatography. The chemical structures of these compounds were identified by spectroscopic analysis and comparison with values reported in the literature. Among the flavonoids tested, 7-hydroxy-6-methoxyflavanone (1) and formononetin (4) exhibited strong inhibitory activity against Streptococcus mutans SrtA, with IC50 values of 46.1 and 41.8 µM, respectively, but did not affect cell viability...
June 16, 2017: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28617845/frequency-and-significance-of-rare-rnf213-variants-in-patients-with-adult-moyamoya-disease
#15
Mi-Ae Jang, Jong-Won Chung, Je Young Yeon, Jong-Soo Kim, Seung Chyul Hong, Oh Young Bang, Chang-Seok Ki
PURPOSE: Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by stenosis of the internal carotid arteries with compensatory development of collateral vessels. Although a founder variant of RNF213, p.Arg4810Lys (c.14429G>A, rs112735431), is a major genetic risk factor for MMD in East Asians, the frequency and disease susceptibility of other variants in this gene remain largely unknown. In the present study, we investigated the association of RNF213 variants with MMD in Korean patients and population controls...
2017: PloS One
https://www.readbyqxmd.com/read/28597870/potential-bias-factors-that-affect-the-course-evaluation-of-students-in-preclinical-courses
#16
Su Jin Chae, Miran Kim, Ki Hong Chang, Yoon-Sok Chung
PURPOSE: We aim to identify what potential bias factors affected students' overall course evaluation, and to observe what factors should be considered in the curriculum evaluation system of medical schools. METHODS: This study analyzed students' ratings of preclinical instructions at the Ajou University School of Medicine. The ratings of instructions involved 41 first-year and 45 second-year medical students. RESULTS: There was a statistically significant difference between years of study and ratings' scoring...
June 2017: Korean Journal of Medical Education
https://www.readbyqxmd.com/read/28579941/chronic-ketamine-exposure-causes-white-matter-microstructural-abnormalities-in-adolescent-cynomolgus-monkeys
#17
Qi Li, Lin Shi, Gang Lu, Hong-Luan Yu, Fu-Ki Yeung, Nai-Kei Wong, Lin Sun, Kai Liu, David Yew, Fang Pan, De-Feng Wang, Pak C Sham
Acute and repeated exposures to ketamine mimic aspects of positive, negative, and cognitive symptoms of schizophrenia in humans. Recent studies by our group and others have shown that chronicity of ketamine use may be a key element for establishing a more valid model of cognitive symptoms of schizophrenia. However, current understanding on the long-term consequences of ketamine exposure on brain circuits has remained incomplete, particularly with regard to microstructural changes of white matter tracts that underpin the neuropathology of schizophrenia...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28572614/early-detection-and-serial-monitoring-of-anthracycline-induced-cardiotoxicity-using-t1-mapping-cardiac-magnetic-resonance-imaging-an-animal-study
#18
Yoo Jin Hong, Heae Surng Park, Jeffrey Kihyun Park, Kyunghwa Han, Chul Hwan Park, Tai Kyung Kim, Sae Jong Yoo, Ji Yeon Lee, Pan Ki Kim, Jin Hur, Hye-Jeong Lee, Young Jin Kim, Young Joo Suh, Mun Young Paek, Byoung Wook Choi
A reliable, non-invasive diagnostic method is needed for early detection and serial monitoring of cardiotoxicity, a well-known side effect of chemotherapy. This study aimed to assess the feasibility of T1-mapping cardiac magnetic resonance imaging (CMR) for evaluating subclinical myocardial changes in a doxorubicin-induced cardiotoxicity rabbit model. Adult male New Zealand White rabbits were injected twice-weekly with doxorubicin and subjected to CMR on a clinical 3T MR system before and every 2-4 weeks post-drug administration...
June 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28564637/efficacy-and-safety-of-neoadjuvant-folfirinox-for-borderline-resectable-pancreatic-adenocarcinoma-improved-efficacy-compared-with-gemcitabine-based-regimen
#19
Changhoon Yoo, Jihoon Kang, Kyu-Pyo Kim, Jae-Lyun Lee, Baek-Yeol Ryoo, Heung-Moon Chang, Sang Soo Lee, Do Hyun Park, Tae Jun Song, Dong Wan Seo, Sung Koo Lee, Myung-Hwan Kim, Jin-Hong Park, Dae Wook Hwang, Ki Byung Song, Jae Hoon Lee, Song Cheol Kim
Borderline resectable pancreatic cancer (BRPC) is a potentially resectable disease but is associated with poorer survival compared to primary resectable disease. There has been no prospective trial that compare the efficacy of FOLFIRNOX and gemcitabine-based regimen for BRPC. Between February 2013 and December 2014, 18 patients with BRPC receiving FOLFIRINOX were reviewed retrospectively. For comparative analysis, data for all BRPC patients (n=18) in our previous phase 2 study of neoadjuvant fixed-dose rate-gemcitabine plus capecitabine were pooled...
July 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28562828/inhibitory-effects-on-the-production-of-inflammatory-mediators-and-reactive-oxygen-species-by-mori-folium-in-lipopolysaccharide-stimulated-macrophages-and-zebrafish
#20
DA Hye Kwon, Jin Woo Jeong, Eun Ok Choi, Hye Won Lee, Ki Won Lee, Ki Young Kim, Sung Goo Kim, Su Hyun Hong, Gi-Young Kim, Cheol Park, Hye-Jin Hwang, Chang-Gue Son, Yung Hyun Choi
Mori folium, the leaf of Morus alba L. (Moraceae), has been traditionally used for various medicinal purposes from ancient times to the present. In this study, we examined the effects of water extract of Mori folium (WEMF) on the production of inflammatory mediators, such as nitric oxide (NO) and prostaglandin E2 (PGE2), and reactive oxygen species (ROS) in lipopolysaccharide (LPS)-stimulated murine RAW 264.7 macrophages. Our data indicated that WEMF significantly suppressed the secretion of NO and PGE2 in RAW 264...
May 2017: Anais da Academia Brasileira de Ciências
keyword
keyword
86917
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"