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https://www.readbyqxmd.com/read/29427849/luminance-polarity-distribution-across-the-symmetry-axis-affects-the-electrophysiological-response-to-symmetry
#1
Damien Wright, Claire Mitchell, Benjamin R Dering, Elena Gheorghiu
Electrophysiological studies of symmetry have found a difference wave termed the Sustained Posterior Negativity (SPN) related to the presence of symmetry. Yet the extent to which the SPN is modulated by luminance-polarity and colour content is unknown. Here we examine how luminance-polarity distribution across the symmetry axis, grouping by luminance polarity, and the number of colours in the stimuli, modulate the SPN. Stimuli were dot patterns arranged either symmetrically or quasi-randomly. There were several arrangements: 'segregated'-symmetric dots were of one polarity and random dots of the other; 'unsegregated'-symmetric dots were of both polarities in equal proportions; 'anti-symmetric'-dots were of opposite polarity across the symmetry axis; 'polarity-grouped anti-symmetric'-as anti-symmetric but with half the pattern of one polarity and the other opposite; multi-colour symmetric patterns made of either two, three and four colours...
February 7, 2018: NeuroImage
https://www.readbyqxmd.com/read/29401159/late-spontaneous-dislocation-of-an-ab-interno-gelatin-microstent
#2
Erin A Boese, Manjool Shah
PURPOSE: To report a case of spontaneous dislocation of a gelatin microstent six months after the initial uncomplicated surgery. PATIENTS AND METHODS: We describe a 73-year-old male with a history of advanced primary open angle glaucoma who had previously undergone an unsuccessful micropulse transcleral cyclophotocoagulation (CPC) of the left eye. He underwent an uncomplicated combined phacoemulsification with an ab interno gelatin microstent, but was noted to have a spontaneous dislocation of the microstent six months post-operatively...
February 2, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29352255/offline-stimulation-of-human-parietal-cortex-differently-affects-resting-eeg-microstates
#3
Pierpaolo Croce, Filippo Zappasodi, Paolo Capotosto
The interference effects of transcranial magnetic stimulation (TMS) on several electroencephalographic (EEG) measures in both temporal and frequency domains have been reported. We tested the hypothesis whether the offline external inhibitory interference, although focal, could result in a global reorganization of the functional brain state, as assessed by EEG microstates. In 16 healthy subjects, we inhibited five parietal areas and used a pseudo stimulation (Sham) at rest. The EEG microstates were extracted before and after each stimulation...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29347348/consciousness-as-a-global-property-of-brain-dynamic-activity
#4
D M Mateos, R Wennberg, R Guevara, J L Perez Velazquez
We seek general principles of the structure of the cellular collective activity associated with conscious awareness. Can we obtain evidence for features of the optimal brain organization that allows for adequate processing of stimuli and that may guide the emergence of cognition and consciousness? Analyzing brain recordings in conscious and unconscious states, we followed initially the classic approach in physics when it comes to understanding collective behaviours of systems composed of a myriad of units: the assessment of the number of possible configurations (microstates) that the system can adopt, for which we use a global entropic measure associated with the number of connected brain regions...
December 2017: Physical Review. E
https://www.readbyqxmd.com/read/29330134/a-supplementary-functional-connectivity-microstate-attached-to-the-default-mode-network-in-depression-revealed-by-resting-state-magnetoencephalography
#5
Siqi Zhang, Shui Tian, Mohammad Ridwan Chattun, Hao Tang, Rui Yan, Kun Bi, Zhijian Yao, Qing Lu
Default mode network (DMN) has discernable involvement in the representation of negative, self-referential information in depression. Both increased and decreased resting-state functional connectivity between the anterior and posterior DMN have been observed in depression. These conflicting connectivity differences necessitated further exploration of the resting-state DMN dysfunction in depression. Hence, we investigated the time-varying dynamic interactions within the DMN via functional connectivity microstates in a sub-second level...
January 9, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29323898/caliber-corrected-markov-modeling-c2m2-correcting-equilibrium-markov-models
#6
Purushottam D Dixit, Ken Dill
Rate processes are often modeled using Markov State Models (MSM). Suppose you know a prior MSM, and then learn that your prediction of some particular observable rate is wrong. What is the best way to correct the whole MSM? For example, molecular dynamics simulations of protein folding may sample many microstates, possibly giving correct pathways through them, while also giving the wrong overall folding rate, when compared to experiment. Here, we describe Caliber Corrected Markov Modeling (C2M2): an approach based on the principle of maximum entropy for updating a Markov model by imposing state- and trajectory-based constraints...
January 11, 2018: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/29318353/the-barrel-vascular-reconstruction-device-a%C3%A2-retrospective-observational-multicentric-study
#7
C Kabbasch, A Mpotsaris, V Maus, J C Altenbernd, C Loehr
BACKGROUND AND PURPOSE: The Barrel device is an electrolytically detachable laser cut, closed-cell microstent that is used for neck reconstruction in wide-necked bifurcation and branching aneurysms to support coiling. The key feature is a barrel section that herniates over the aneurysmal ostium. The objective was to evaluate the safety, feasibility and the immediate and mid-term occlusion results of this new device. MATERIAL AND METHODS: The databases of two tertiary care centers were screened for all Barrel-based stent-assisted intracranial coil embolization of wide-necked aneurysms between June 2015 and September 2016...
January 9, 2018: Clinical Neuroradiology
https://www.readbyqxmd.com/read/29258404/xen-gel-implant-a-new-surgical-approach-in-glaucoma
#8
Ankita Chaudhary, Lauriane Salinas, Jacopo Guidotti, André Mermoud, Kaweh Mansouri
Glaucoma is a leading cause of blindness worldwide. Intraocular pressure (IOP) lowering is the only effective treatment strategy. Traditional glaucoma surgeries are generally considered to be unpredictable and associated with a high rate of complications. This has led to the development of a novel XEN Gel Implant, a type of minimally invasive glaucoma surgery (MIGS), lowering the IOP without extensive surgical dissection. Areas covered: A literature search was undertaken on PubMed using the terms XEN glaucoma, gelatin microstent, and MIGS...
January 2018: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/29216191/transcription-factors-coregulators-and-epigenetic-marks-are-linearly-correlated-and-highly-redundant
#9
Tobias Ahsendorf, Franz-Josef Müller, Ved Topkar, Jeremy Gunawardena, Roland Eils
The DNA microstates that regulate transcription include sequence-specific transcription factors (TFs), coregulatory complexes, nucleosomes, histone modifications, DNA methylation, and parts of the three-dimensional architecture of genomes, which could create an enormous combinatorial complexity across the genome. However, many proteins and epigenetic marks are known to colocalize, suggesting that the information content encoded in these marks can be compressed. It has so far proved difficult to understand this compression in a systematic and quantitative manner...
2017: PloS One
https://www.readbyqxmd.com/read/29212344/results-obtained-by-combining-different-estimators-of-eeg-connectivity-become-uninterpretable-if-the-underlying-models-are-incompatible
#10
Thomas Koenig, Pedro A Valdes-Sosa
We comment on a recent paper published in Brain Connectivity (Hatz et al. 2016) that combined EEG microstate analysis with the phase locking index and found that the test-retest reliability of connectivity patterns as obtained by the phase locking index increased when the data had been previously parcellated into microstates. While we acknowledge the need to parcellate the continuous data into periods that supposedly correspond to transiently stable patterns of connectivity, we believe that the approach chosen by the authors is seriously mistaken...
December 6, 2017: Brain Connectivity
https://www.readbyqxmd.com/read/29196270/eeg-microstates-as-a-tool-for-studying-the-temporal-dynamics-of-whole-brain-neuronal-networks-a-review
#11
REVIEW
Christoph M Michel, Thomas Koenig
The present review discusses a well-established method for characterizing resting-state activity of the human brain using multichannel electroencephalography (EEG). This method involves the examination of electrical microstates in the brain, which are defined as successive short time periods during which the configuration of the scalp potential field remains semi-stable, suggesting quasi-simultaneity of activity among the nodes of large-scale networks. A few prototypic microstates, which occur in a repetitive sequence across time, can be reliably identified across participants...
November 28, 2017: NeuroImage
https://www.readbyqxmd.com/read/29188992/tracking-the-catalytic-cycle-of-adenylate-kinase-by-ultraviolet-photodissociation-mass-spectrometry
#12
M Rachel Mehaffey, Michael B Cammarata, Jennifer S Brodbelt
The complex interplay of dynamic protein plasticity and specific side-chain interactions with substrate molecules that allows enzymes to catalyze reactions has yet to be fully unraveled. Top-down ultraviolet photodissociation (UVPD) mass spectrometry is used to track conformational fluctuations of phosphotransferase adenylate kinase (AK) throughout its active reaction cycle by characterization of complexes containing AK and one of four adenosine phosphate ligands. Variations in efficiencies of UVPD backbone cleavages were consistently observed for three α-helices and the adenosine binding regions for AK complexes representing different steps of the catalytic cycle, implying that these stretches of the protein sample various structural microstates as the enzyme undergoes global open-to-closed transitions...
November 30, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29172013/the-association-between-brain-activity-and-motor-imagery-during-motor-illusion-induction-by-vibratory-stimulation
#13
Takayuki Kodama, Hideki Nakano, Osamu Katayama, Shin Murata
BACKGROUND: The association between motor imagery ability and brain neural activity that leads to the manifestation of a motor illusion remains unclear. OBJECTIVE: In this study, we examined the association between the ability to generate motor imagery and brain neural activity leading to the induction of a motor illusion by vibratory stimulation. METHODS: The sample consisted of 20 healthy individuals who did not have movement or sensory disorders...
2017: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/29163110/modeling-uncertainties-in-eeg-microstates-analysis-of-real-and-imagined-motor-movements-using-probabilistic-clustering-driven-training-of-probabilistic-neural-networks
#14
Martin Dinov, Robert Leech
Part of the process of EEG microstate estimation involves clustering EEG channel data at the global field power (GFP) maxima, very commonly using a modified K-means approach. Clustering has also been done deterministically, despite there being uncertainties in multiple stages of the microstate analysis, including the GFP peak definition, the clustering itself and in the post-clustering assignment of microstates back onto the EEG timecourse of interest. We perform a fully probabilistic microstate clustering and labeling, to account for these sources of uncertainty using the closest probabilistic analog to KM called Fuzzy C-means (FCM)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29163017/electrical-neuroimaging-of-music-processing-reveals-mid-latency-changes-with-level-of-musical-expertise
#15
Clara E James, Mathias S Oechslin, Christoph M Michel, Michael De Pretto
This original research focused on the effect of musical training intensity on cerebral and behavioral processing of complex music using high-density event-related potential (ERP) approaches. Recently we have been able to show progressive changes with training in gray and white matter, and higher order brain functioning using (f)MRI [(functional) Magnetic Resonance Imaging], as well as changes in musical and general cognitive functioning. The current study investigated the same population of non-musicians, amateur pianists and expert pianists using spatio-temporal ERP analysis, by means of microstate analysis, and ERP source imaging...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29158603/realization-of-ground-state-in-artificial-kagome-spin-ice-via-topological-defect-driven-magnetic-writing
#16
Jack C Gartside, Daan M Arroo, David M Burn, Victoria L Bemmer, Andy Moskalenko, Lesley F Cohen, Will R Branford
Arrays of non-interacting nanomagnets are widespread in data storage and processing. As current technologies approach fundamental limits on size and thermal stability, enhancing functionality through embracing the strong interactions present at high array densities becomes attractive. In this respect, artificial spin ices are geometrically frustrated magnetic metamaterials that offer vast untapped potential due to their unique microstate landscapes, with intriguing prospects in applications from reconfigurable logic to magnonic devices or hardware neural networks...
November 20, 2017: Nature Nanotechnology
https://www.readbyqxmd.com/read/29119612/are-you-surprised-to-hear-this-longitudinal-spectral-speech-exposure-in-older-compared-to-middle-aged-normal-hearing-adults
#17
Nathalie Giroud, Ulrike Lemke, Philip Reich, Julia Bauer, Susann Widmer, Martin Meyer
Cognitive abilities such as attention or working memory can support older adults during speech perception. However, cognitive abilities as well as speech perception decline with age, leading to the expenditure of effort during speech processing. This longitudinal study therefore investigated age-related differences in electrophysiological processes during speech discrimination, and assessed the extent of enhancement to such cognitive auditory processes through repeated auditory exposure. For that purpose, accuracy and reaction time were compared between 13 older adults (62-76y) and 15 middle-aged (28-52y) controls in an active oddball paradigm which was administered at three consecutive measurement time points at an interval of two weeks, while EEG was recorded...
November 9, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29119281/-swarm-relaxation-equilibrating-a-large-ensemble-of-computer-simulations-%C3%A2
#18
Shahrazad M A Malek, Richard K Bowles, Ivan Saika-Voivod, Francesco Sciortino, Peter H Poole
It is common practice in molecular dynamics and Monte Carlo computer simulations to run multiple, separately-initialized simulations in order to improve the sampling of independent microstates. Here we examine the utility of an extreme case of this strategy, in which we run a large ensemble of M independent simulations (a "swarm"), each of which is relaxed to equilibrium. We show that if M is of order [Formula: see text], we can monitor the swarm's relaxation to equilibrium, and confirm its attainment, within [Formula: see text], where [Formula: see text] is the equilibrium relaxation time...
November 10, 2017: European Physical Journal. E, Soft Matter
https://www.readbyqxmd.com/read/29110122/-suprachoroidal-minimally-invasive-glaucoma-surgery-procedures-and-clinical-outcome
#19
REVIEW
C Erb
The uveoscleral outflow route is via the ciliary muscles into the suprachoroidal spaces and then to the orbital blood and lymph systems. The main driving force behind this uveoscleral outflow is the high oncotic pressure in the choroidal vessels. Currently, the CyPass microstent is the only available suprachoroidal device for ab interno minimally invasive glaucoma surgery. The CyPass achieves a maximum reduction of intraocular pressure (IOP) to 16-17 mm Hg over 12-24 months and is approved for mild to moderate primary open-angle glaucoma...
November 6, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29096552/exploring-differences-between-left-and-right-hand-motor-imagery-via-spatio-temporal-eeg-microstate
#20
Weifeng Liu, Xiaoming Liu, Ruomeng Dai, Xiaoying Tang
EEG-based motor imagery is very useful in brain-computer interface. How to identify the imaging movement is still being researched. Electroencephalography (EEG) microstates reflect the spatial configuration of quasi-stable electrical potential topographies. Different microstates represent different brain functions. In this paper, microstate method was used to process the EEG-based motor imagery to obtain microstate. The single-trial EEG microstate sequences differences between two motor imagery tasks - imagination of left and right hand movement were investigated...
November 3, 2017: Computer Assisted Surgery (Abingdon, England)
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