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Phase amplitude coupling

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https://www.readbyqxmd.com/read/28735144/entorhinal-tau-pathology-disrupts-hippocampal-prefrontal-oscillatory-coupling-during-associative-learning
#1
Stephanie E Tanninen, Bardia Nouriziabari, Mark D Morrissey, Rami Bakir, Robert D Dayton, Ronald L Klein, Kaori Takehara-Nishiuchi
A neural signature of asymptomatic preclinical Alzheimer's disease (AD) is disrupted connectivity between brain regions; however, its underlying mechanisms remain unknown. Here, we tested whether a preclinical pathologic feature, tau aggregation in the entorhinal cortex (EC) is sufficient to disrupt the coordination of local field potentials (LFPs) between its efferent regions. P301L-mutant human tau or green fluorescent protein (GFP) was virally overexpressed in the EC of adult rats. LFPs were recorded from the dorsal hippocampus and prelimbic medial prefrontal cortex while the rats underwent trace eyeblink conditioning where they learned to associate 2 stimuli separated by a short time interval...
July 6, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28734290/effect-of-interlamellar-interactions-on-shear-induced-multilamellar-vesicle-formation
#2
Y Kawabata, R Bradbury, S Kugizaki, K Weigandt, Y B Melnichenko, K Sadakane, N L Yamada, H Endo, M Nagao, H Seto
Shear-induced multilamellar vesicle (MLV) formation has been studied by coupling the small-angle neutron scattering (SANS) technique with neutron spin echo (NSE) spectroscopy. A 10% mass fraction of the nonionic surfactant pentaethylene glycol dodecyl ether (C12E5) in water was selected as a model system for studying weak inter-lamellar interactions. These interactions are controlled either by adding an anionic surfactant, sodium dodecyl sulfate, or an antagonistic salt, rubidium tetraphenylborate. Increasing the charge density in the bilayer induces an enhanced ordering of the lamellar structure...
July 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28729438/electrophysiological-evidence-that-the-retrosplenial-cortex-displays-a-strong-and-specific-activation-phased-with-hippocampal-theta-during-paradoxical-rem-sleep
#3
Koike Bruna Del Vechio, Farias Kelly Soares, Billwiller Francesca, Almeida-Filho Daniel, Libourel Paul-Antoine, Tiran-Cappello Alix, Parmentier Régis, Blanco Wilfredo, Ribeiro Sidarta, Luppi Pierre-Herve, Queiroz Claudio Marcos
It is widely accepted that cortical neurons are similarly more activated during waking and paradoxical sleep (PS, aka REM) than during slow wave sleep (SWS). However, we recently reported using Fos labeling that only a few limbic cortical structures including the retrosplenial (RSC) and anterior cingulate (ACA) cortices contain a large number of neurons activated during PS hypersomnia. Our aim in the present study was to record local field potentials (LFPs) and unit activity from these two structures across all vigilance states in freely moving male rats to determine whether the RSC and the ACA are electrophysiologically specifically active during basal PS episodes...
July 20, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28726858/pumping-and-probing-vibrational-modulated-coupled-electronic-coherence-in-hcn-using-short-uv-fs-laser-pulses-a-2d-quantum-nuclear-dynamical-study
#4
S van den Wildenberg, B Mignolet, R D Levine, F Remacle
The coupled electronic-nuclear coherent dynamics induced by a short strong VUV fs pulse in the low excited electronic states of HCN is probed by transient absorption spectroscopy with a second weaker fs UV pulse. The nuclear time-dependent Schrodinger equation is solved on a 2D nuclear grid with several electronic states with a Hamiltonian including the dipole coupling to the pump and the probe electric fields. The two internal nuclear coordinates describe the motion of the light H atom. There is a band of several excited electronic states at about 8 eV above the ground state (GS) that is transiently accessed by the pump pulse...
July 20, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28709240/extreme-events-in-fitzhugh-nagumo-oscillators-coupled-with-two-time-delays
#5
Arindam Saha, Ulrike Feudel
We study two identical FitzHugh-Nagumo oscillators which are coupled with one or two different time delays. If only a single-delay coupling is used, the length of the delay determines whether the synchronization manifold is transversally stable or unstable, exhibiting mixed-mode or chaotic oscillations in which the small amplitude oscillations are always in phase but the large amplitude oscillations are in phase or out of phase, respectively. For two delays we find an intricate dynamics which comprises an irregular alteration of small amplitude oscillations, in-phase and out-of-phase large amplitude oscillations, also called extreme events...
June 2017: Physical Review. E
https://www.readbyqxmd.com/read/28708551/indoor-airborne-ultrasonic-wireless-communication-using-ofdm-methods
#6
Wentao Jiang, William M D Wright
Concerns still exist over the safety of prolonged exposure to radio frequency (RF) wireless transmissions and there are also potential data security issues due to remote signal interception techniques such as Bluesniping. Airborne ultrasound may be used as an alternative to RF for indoor wireless communication systems for securely transmitting data over short ranges, as signals are difficult to intercept from outside the room. Two types of air-coupled capacitive ultrasonic transducer were used in the implementation of an indoor airborne wireless communication system...
July 11, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28679224/temporal-intermittency-and-the-lifetime-of-chimera-states-in-ensembles-of-nonlocally-coupled-chaotic-oscillators
#7
N I Semenova, G I Strelkova, V S Anishchenko, A Zakharova
We describe numerical results for the dynamics of networks of nonlocally coupled chaotic maps. Switchings in time between amplitude and phase chimera states have been first established and studied. It has been shown that in autonomous ensembles, a nonstationary regime of switchings has a finite lifetime and represents a transient process towards a stationary regime of phase chimera. The lifetime of the nonstationary switching regime can be increased to infinity by applying short-term noise perturbations.
June 2017: Chaos
https://www.readbyqxmd.com/read/28673716/contribution-of-the-supplementary-motor-area-and-the-cerebellum-to-the-anticipatory-postural-adjustments-and-execution-phases-of-human-gait-initiation
#8
Aliénor Richard, Angèle Van Hamme, Xavier Drevelle, Jean-Louis Golmard, Sabine Meunier, Marie-Laure Welter
Several brain structures including the brainstem, the cerebellum and the frontal cortico-basal ganglia network, with the primary and premotor areas have been shown to participate in the functional organization of gait initiation and postural control in humans, but their respective roles remain poorly understood. The aim of this study was to better understand the role of the supplementary motor area (SMA) and posterior cerebellum in the gait initiation process. Gait initiation parameters were recorded in 22 controls both before and after continuous theta burst transcranial stimulation (cTBS) of the SMA and cerebellum, and were compared to sham stimulation, using a randomized double-blind design study...
July 1, 2017: Neuroscience
https://www.readbyqxmd.com/read/28668004/a-compact-two-way-power-divider-based-on-five-port-structure
#9
Letian Guo, Jiawei Li, Wenhua Huang, Hao Shao, Tao Ba, Shaoyi Xie
A novel compact five-port waveguide power divider based on the single-ridge waveguide and three-ridge waveguide structure is proposed. It is realized by the coupling of the TE10 and TE30 modes. At the central coupling section, the single-ridge and three-ridge waveguides are used to constitute the conventional rectangular waveguide to reduce the sectional sizes. It consists of one input port, two output ports, and two isolated ports. For validation, a compact five-port power divider is designed, fabricated, and measured...
June 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28667703/hippocampal-gamma-slow-oscillation-coupling-in-macaques-during-sedation-and-sleep
#10
Andrew G Richardson, Xilin Liu, Pauline K Weigand, Eric D Hudgins, Joel M Stein, Sandhitsu R Das, Alexander Proekt, Max B Kelz, Milin Zhang, Jan Van der Spiegel, Timothy H Lucas
Behavioral and neurophysiological evidence suggests that the slow (≤ 1 Hz) oscillation (SO) during sleep plays a role in consolidating hippocampal (HIPP)-dependent memories. The effects of the SO on HIPP activity have been studied in rodents and cats both during natural sleep and during anesthetic administration titrated to mimic sleep-like slow rhythms. In this study, we sought to document these effects in primates. First, HIPP field potentials were recorded during ketamine-dexmedetomidine sedation and during natural sleep in three rhesus macaques...
July 1, 2017: Hippocampus
https://www.readbyqxmd.com/read/28659769/propofol-sevoflurane-and-ketamine-induce-a-reversible-increase-in-delta-gamma-and-theta-gamma-phase-amplitude-coupling-in-frontal-cortex-of-rat
#11
Dinesh Pal, Brian H Silverstein, Lana Sharba, Duan Li, Viviane S Hambrecht-Wiedbusch, Anthony G Hudetz, George A Mashour
Studies from human and non-human species have demonstrated a breakdown of functional corticocortical connectivity during general anesthesia induced by anesthetics with diverse molecular, neurophysiological, and pharmacological profiles. Recent studies have demonstrated that changes in long-range neural communication, and by corollary, functional connectivity, might be influenced by cross-frequency coupling (CFC) between the phase of slow oscillations and the amplitude of local fast oscillations. Phase-amplitude coupling (PAC) between slow oscillations and alpha rhythm during general anesthesia reveal distinct patterns depending on the anesthetic...
2017: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/28632051/quantifying-coordination-among-the-rearfoot-midfoot-and-forefoot-segments-during-running
#12
Tomoya Takabayashi, Mutsuaki Edama, Erika Yokoyama, Chiaki Kanaya, Masayoshi Kubo
Because previous studies have suggested that there is a relationship between injury risk and inter-segment coordination, quantifying coordination between the segments is essential. Even though the midfoot and forefoot segments play important roles in dynamic tasks, previous studies have mostly focused on coordination between the shank and rearfoot segments. This study aimed to quantify coordination among rearfoot, midfoot, and forefoot segments during running. Eleven healthy young men ran on a treadmill. The coupling angle, representing inter-segment coordination, was calculated using a modified vector coding technique...
February 28, 2017: Sports Biomechanics
https://www.readbyqxmd.com/read/28621980/converting-quasiclassical-states-into-arbitrary-fock-state-superpositions-in-a-superconducting-circuit
#13
W Wang, L Hu, Y Xu, K Liu, Y Ma, Shi-Biao Zheng, R Vijay, Y P Song, L-M Duan, L Sun
We propose and experimentally demonstrate a new method to generate arbitrary Fock state superpositions in a superconducting quantum circuit, where a qubit is dispersively coupled to a microwave cavity mode. Here, the qubit is used to conditionally modulate the probability amplitudes of the Fock state components of a coherent state to those of the desired superposition state, instead of pumping photons one by one into the cavity as in previous schemes. Our method does not require the adjustment of the qubit frequency during the cavity state preparation and is more robust to noise and accumulation of experimental errors compared to previous ones...
June 2, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28612156/reduction-of-sr-ca-2-leak-and-arrhythmogenic-cellular-correlates-by-smp-114-a-novel-camkii-inhibitor-with-oral-bioavailability
#14
Stefan Neef, Christian Mann, Anne Zwenger, Nataliya Dybkova, Lars S Maier
Sarcoplasmic reticulum (SR) Ca(2+) leak induced by Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is centrally involved in atrial and ventricular arrhythmogenesis as well as heart failure remodeling. Consequently, treating SR Ca(2+) leak has been proposed as a novel therapeutic paradigm, but compounds for use in humans are lacking. SMP-114 ("Rimacalib") is a novel, orally available CaMKII inhibitor developed for human use that has already entered clinical phase II trials to treat rheumatoid arthritis...
July 2017: Basic Research in Cardiology
https://www.readbyqxmd.com/read/28610902/post-stimulus-fmri-and-eeg-responses-evidence-for-a-neuronal-origin-hypothesised-to-be-inhibitory
#15
K J Mullinger, M T Cherukara, R B Buxton, S T Francis, S D Mayhew
Post-stimulus undershoots, negative responses following cessation of stimulation, are widely observed in functional magnetic resonance (fMRI) blood oxygenation level dependent (BOLD) data. However, the debate surrounding whether the origin of this response phase is neuronal or vascular, and whether it provides functionally relevant information, that is additional to what is contained in the primary response, means that undershoots are widely overlooked. We simultaneously recorded electroencephalography (EEG), BOLD and cerebral blood-flow (CBF) [obtained from arterial spin labelled (ASL) fMRI] fMRI responses to hemifield checkerboard stimulation to test the potential neural origin of the fMRI post-stimulus undershoot...
June 10, 2017: NeuroImage
https://www.readbyqxmd.com/read/28608044/parametric-sensitivity-analysis-of-oscillatory-delay-systems-with-an-application-to-gene-regulation
#16
Brian Ingalls, Maya Mincheva, Marc R Roussel
A parametric sensitivity analysis for periodic solutions of delay-differential equations is developed. Because phase shifts cause the sensitivity coefficients of a periodic orbit to diverge, we focus on sensitivities of the extrema, from which amplitude sensitivities are computed, and of the period. Delay-differential equations are often used to model gene expression networks. In these models, the parametric sensitivities of a particular genotype define the local geometry of the evolutionary landscape. Thus, sensitivities can be used to investigate directions of gradual evolutionary change...
June 12, 2017: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/28596820/neural-synchronization-deficits-linked-to-cortical-hyper-excitability-and-auditory-hypersensitivity-in-fragile-x-syndrome
#17
Lauren E Ethridge, Stormi P White, Matthew W Mosconi, Jun Wang, Ernest V Pedapati, Craig A Erickson, Matthew J Byerly, John A Sweeney
BACKGROUND: Studies in the fmr1 KO mouse demonstrate hyper-excitability and increased high-frequency neuronal activity in sensory cortex. These abnormalities may contribute to prominent and distressing sensory hypersensitivities in patients with fragile X syndrome (FXS). The current study investigated functional properties of auditory cortex using a sensory entrainment task in FXS. METHODS: EEG recordings were obtained from 17 adolescents and adults with FXS and 17 age- and sex-matched healthy controls...
2017: Molecular Autism
https://www.readbyqxmd.com/read/28592690/dynamics-of-human-subthalamic-neuron-phase-locking-to-motor-and-sensory-cortical-oscillations-during-movement
#18
Witold J Lipski, Thomas A Wozny, Ahmad Alhourani, Efstathios Kondylis, Robert S Turner, Donald J Crammond, Robert Mark Richardson
Coupled oscillatory activity recorded between sensorimotor regions of the basal ganglia-thalamocortical loop is thought to reflect information transfer relevant to movement. A neuronal firing-rate model of basal ganglia-thalamocortical circuitry, however, has dominated thinking about basal ganglia function for the past three decades, without knowledge of the relationship between basal ganglia single neuron firing and cortical population activity during movement itself. We recorded activity from 34 subthalamic nucleus (STN) neurons, simultaneously with cortical local field potentials and motor output, in eleven subjects with Parkinson's disease (PD) undergoing awake deep brain stimulator lead placement...
June 7, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28579102/wideband-frequency-swept-excitation-in-pulsed-epr-spectroscopy
#19
Andrin Doll, Gunnar Jeschke
Excitation of electron spins with monochromatic rectangular pulses is limited to bandwidths that are smaller than the spectral widths of most organic radicals and much smaller than the spectral widths of transition and rare earth metal ions. With frequency-swept pulses, bandwidths of up to 800MHz have previously been attained for excitation and detection of spin packets at frequencies of about 9.6GHz and bandwidths of up to 2.5GHz in a polarization transfer experiment at frequencies of about 34GHz. The remaining limitations, mainly due to resonator bandwidth and due to pulse length restrictions are discussed...
July 2017: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/28555125/determinants-of-motion-sickness-in-tilting-trains-coriolis-cross-coupling-stimuli-and-tilt-delay
#20
Giovanni Bertolini, Meek Angela Durmaz, Kim Ferrari, Alexander Küffer, Charlotte Lambert, Dominik Straumann
Faster trains require tilting of the cars to counterbalance the centrifugal forces during curves. Motion sensitive passengers, however, complain of discomfort and overt motion sickness. A recent study comparing different control systems in a tilting train, suggested that the delay of car tilts relative to the curve of the track contributes to motion sickness. Other aspects of the motion stimuli, like the lateral accelerations and the car jitters, differed between the tested conditions and prevented a final conclusion on the role of tilt delay...
2017: Frontiers in Neurology
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