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https://www.readbyqxmd.com/read/29781922/screening-for-sexually-transmitted-infections-after-cervical-cancer-screening-guideline-and-medicaid-policy-changes-a-population-based-analysis
#1
Natasha Parekh, Julie M Donohue, Jennifer Corbelli, Aiju Men, David Kelley, Marian Jarlenski
BACKGROUND: Sexually transmitted infection (STI) screening prevents complications and is cost-effective. Annual screening is recommended in sexually active women <25 years and older women at increased risk. Cervical cancer (CC) screening guideline changes in 2009 and 2012 recommended less frequent screening, causing concern that STI screening would decrease. Pennsylvania Medicaid implemented a family planning program in 2007 which covered women's health services (including STI testing) for uninsured women...
May 17, 2018: Medical Care
https://www.readbyqxmd.com/read/29781754/taking-a-snapshot-evaluation-of-a-conversation-aid-for-identifying-psychosocial-needs-in-young-adults-with-cancer
#2
Hanneke Poort, Phoebe M Souza, Paige K Malinowski, Katelyn M MacDougall, Constance M Barysauskas, Teresa Lau Greenberg, James A Tulsky, Karen M Fasciano
PURPOSE: Young adults (YAs) aged 18-35 years with cancer often experience unmet psychosocial needs. We aimed to evaluate a conversation aid ("Snapshot") that offered a framework for discussing YA-specific psychosocial concerns between patients and clinicians. METHODS: We developed and implemented Snapshot between 2014 and 2016 as part of a quality improvement initiative at Dana-Farber Cancer Institute. We extracted pre- and postimplementation data from chart documentation of psychosocial concerns...
May 21, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29781039/sex-dependent-association-of-circulating-sex-steroids-and-pituitary-hormones-with-treatment-free-survival-in-chronic-lymphocytic-leukemia-patients
#3
Eric P Allain, Karin Venzl, Patrick Caron, Véronique Turcotte, David Simonyan, Michaela Gruber, Trang Le, Eric Lévesque, Chantal Guillemette, Katrina Vanura
Chronic lymphocytic leukemia (CLL) is not considered a hormone-regulated cancer although sex is a recognized risk factor with men more frequently diagnosed and developing progressive disease. We hypothesized that variable hormonal exposure may have a sexually dimorphic influence on treatment-free survival (TFS). In 156 CLL cases, we quantitatively profiled 29 circulating steroids (progesterone, adrenal precursors, androgens, estrogens, and catechol estrogens) as well as luteinizing hormone (LH) and follicle-stimulating hormone...
May 21, 2018: Annals of Hematology
https://www.readbyqxmd.com/read/29777397/telomeres-and-telomerase-during-human-papillomavirus-induced-carcinogenesis
#4
REVIEW
Anna Pańczyszyn, Ewa Boniewska-Bernacka, Grzegorz Głąb
Human papillomaviruses (HPVs) belong to a small spherical virus family and are transmitted through direct contact, most often through sexual behavior. More than 200 types of HPV are known, a dozen or so of which are classified as high-risk viruses (HR HPV) and may contribute to the development of cervical cancer. HPV is a small virus with a capsid composed of L1 and L2 proteins, which are crucial for entry to the cell. The infection begins at the basal cell layer and progresses to involve cells from higher layers of the cervical epithelium...
May 18, 2018: Molecular Diagnosis & Therapy
https://www.readbyqxmd.com/read/29777382/mood-sexuality-and-relational-intimacy-after-starting-androgen-deprivation-therapy-implications-for-couples
#5
Lauren M Walker, Pablo Santos-Iglesias, John Robinson
BACKGROUND: Patients on androgen deprivation therapy (ADT), a common treatment for prostate cancer, report significant declines in quality of life and detrimental impact on their intimate relationships. ADT depresses a man's testosterone to castrate levels, leading to declines in sexual function, and changes in mood. These changes can have profound impact on couples' intimate relationships. METHOD: Patients undergoing ADT, and their consenting partners, were followed on a variety of outcomes relating to mood, sexual changes, and relational intimacy...
May 18, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29770611/the-changing-aetiology-of-head-and-neck-squamous-cell-cancer-a-tale-of-three-cancers
#6
Steven J Thomas, Chris M Penfold, Andrea Waylen, Andrew R Ness
Head and neck cancers are the sixth most common cancers worldwide and an important cause of ill health.(1) Each year about 9000 cases are reported in the UK.(2) Survival is poor and despite advances in treatment, has not improved until recently.(3) The majority of head and neck cancers are squamous cell carcinomas, affecting the larynx, oropharynx and oral cavity. The aetiology is changing and this has implications for prevention and treatment. Twenty years ago, tobacco and alcohol consumption were considered to be the established risk factors and it was estimated that these risk factors accounted for about 75% of cases...
May 16, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29770079/summary-of-the-naci-update-on-the-recommended-use-of-human-papillomavirus-hpv-vaccine-nine-valent-hpv-vaccine-two-dose-immunization-schedule-and-the-use-of-hpv-vaccines-in-immunocompromised-populations
#7
S L Deeks, M C Tunis, S Ismail
Background: Human papillomavirus (HPV) infections are the most common sexually transmitted infections. In the absence of vaccination, it is estimated that 75% of sexually active Canadians will have an HPV infection at some point in their lives. HPV vaccine programs were first recommended by Canada's National Advisory Committee on Immunization (NACI) in 2007. In addition to the existing HPV vaccine options in Canada, NACI recently recommended the use of a newly authorized nine-valent HPV (HPV9) vaccine according to a 3-dose immunization schedule for the prevention of HPV types 6-, 11-, 16-, 18-, 31-, 33-, 45-, 52- and 58-related cancers and anogenital warts in females aged 9 to 45 years and males aged 9 to 26 years...
June 1, 2017: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29768419/a-secreted-heat-shock-protein-90-of-trichomonas-vaginalis
#8
Meetali Singh, Divya Beri, Rishi Kumar Nageshan, Leena Chavaan, Darshak Gadara, Mukta Poojary, Suraj Subramaniam, Utpal Tatu
Trichomonas vaginalis is a causative agent of Trichomoniasis, a leading non-viral sexually transmitted disease worldwide. In the current study, we show Heat shock protein 90 is essential for its growth. Upon genomics analysis of the parasite, it was found to possess seven ORFs which could potentially encode Hsp90 isoforms. We identified a cytosolic Hsp90 homolog, four homologs which can align to truncated cytosolic Hsp90 gene products along with two Grp94 homologs (ER isoform of Hsp90). However, both Grp94 orthologs lacked an ER retention motif...
May 16, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29768322/lung-cancer-screening-ct-based-coronary-artery-calcification-in-predicting-cardiovascular-events-a-systematic-review-and-meta-analysis
#9
Lili Fan, Kaikai Fan
BACKGROUND: Coronary artery calcificition (CAC) is a well-established predictor of cardiovascular events (CVEs). We aimed to evaluate whether lung cancer screening computed tomography (CT)-based CAC score has a good cost-effectiveness for predicting CVEs in heavy smokers. METHODS: A literature search was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Pubmed, EMBASE, and Cochrane library databases were systematically searched for relevant studies that investigated the association between lung cancer screening CT-based CAC and CVEs up to December 31, 2017...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29767912/gender-differences-in-the-perception-of-quality-of-life-of-patients-with-colorectal-cancer
#10
Isadora Trinquinato, Rodrigo Marques da Silva, Sonia Betzabeth Ticona Benavente, Camila Cristine Antonietti, Ana Lúcia Siqueira Costa Calache
OBJECTIVES: To identify the gender differences in assessing quality of life of patients undergoing chemotherapy treatment for colorectal cancer. METHODS: This is a cross-sectional investigation conducted with 144 patients (72 men and 72 women) undergoing chemotherapy treatment in a southeastern Brazilian hospital. Data were gathered trough a sociodemographic and clinical information form and the Health-related Quality of Life instrument from the European Organization for Research and Treatment of Cancer...
October 2017: Investigación y Educación en Enfermería
https://www.readbyqxmd.com/read/29762200/management-of-genitourinary-syndrome-of-menopause-in-women-with-or-at-high-risk-for-breast-cancer-consensus-recommendations-from-the-north-american-menopause-society-and-the-international-society-for-the-study-of-women-s-sexual-health
#11
(no author information available yet)
No abstract text is available yet for this article.
May 14, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29759898/risk-factors-for-human-papillomavirus-detection-in-urine-samples-of-heterosexual-men-visiting-urological-clinics-in-japan
#12
Kazufumi Nakashima, Kazuyoshi Shigehara, Tadaichi Kitamura, Hiroshi Yaegashi, Masayoshi Shimamura, Shohei Kawaguchi, Kouji Izumi, Yoshifumi Kadono, Atsushi Mizokami
OBJECTIVE: The present study aimed to investigate human papillomavirus (HPV) prevalence and identify risk factors for HPV detection in urine samples among heterosexual men attending urological clinics. MATERIALS AND METHODS: Spot urine samples including initial stream were collected from 845 participants, and the cell pellets were preserved into liquid-based cytological solution. After DNA extraction from each sample, HPV-DNA amplification and genotyping were performed using Luminex multiplex polymerase chain reaction...
May 11, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29755116/health-related-quality-of-life-after-treatment-for-bladder-cancer-in-england
#13
Samantha J Mason, Amy Downing, Penny Wright, Luke Hounsome, Sarah E Bottomley, Jessica Corner, Mike Richards, James W Catto, Adam W Glaser
BACKGROUND: Little is known about quality of life after bladder cancer treatment. This common cancer is managed using treatments that can affect urinary, sexual and bowel function. METHODS: To understand quality of life and inform future care, the Department of Health (England) surveyed adults surviving bladder cancer 1-5 years after diagnosis. Questions related to disease status, co-existing conditions, generic health (EQ-5D), cancer-generic (Social Difficulties Inventory) and cancer-specific outcomes (Functional Assessment of Cancer Therapy-Bladder)...
May 14, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29752836/effect-of-a-diagonal-intervention-on-uptake-of-hiv-and-reproductive-health-services-by-female-sex-workers-in-three-sub-saharan-african-cities
#14
Yves Lafort, Letitia Greener, Faustino Lessitala, Sophie Chabeda, Ross Greener, Mags Beksinska, Peter Gichangi, Sally Griffin, Jenni A Smit, Matthew Chersich, Wim Delva
OBJECTIVES: To enhance uptake of sexual and reproductive health (SRH) services by female sex workers (FSWs), we conducted an implementation study in which we piloted and tested context-specific 'diagonal' interventions, combining vertical, targeted interventions with horizontally improved access to the general health services, in three cities in sub-Saharan Africa. METHODS: We collected indicators of SRH service uptake through face-to-face interviews with approximately 400 FSWs, pre- and post-intervention, in Durban, South Africa; Tete, Mozambique; and Mombasa, Kenya, recruited by respondent-driven sampling...
May 12, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29744304/insights-for-public-education-provided-by-french-media-on-ideas-about-prostate-cancer-a-media-analysis-study
#15
Margareth S Zanchetta, Marguerite Cognet, Mary Rachel Lam-Kin-Teng, Marie Elisabeth Dumitriu, Carlos Haag, Bernard Kadio, François Desgrandchamps, Lise Rénaud
Background: This study explored the French media's presentation of ideas and medical information about prostate cancer (PC) that may influence men's understanding, attitudes and behavior. Methods: A qualitative media content analysis centered on PC information delivered by French professional media. The selected data were produced in the aftermath of the High Health Authority's decision in 2008 not to recommend systematic screening by prostate specific antigen(PSA) for men over 50. Source was the Media Archives of the French National Library...
2018: Health Promotion Perspectives
https://www.readbyqxmd.com/read/29743199/evaluation-of-dried-blood-spots-and-oral-fluids-as-alternatives-to-serum-for-human-papillomavirus-antibody-surveillance
#16
Karly S Louie, Jama Dalel, Caroline Reuter, Sara L Bissett, Michelle Kleeman, Lesley Ashdown-Barr, Rawinder Banwait, Anna Godi, Peter Sasieni, Simon Beddows
Human papillomavirus (HPV) vaccination elicits high-titer genotype-specific antibody responses that are associated with a reduced risk of cervical disease caused by vaccine-incorporated genotypes. Our objective was to evaluate dried blood spots (DBSs) and oral mucosal transudate (OMT) as alternative samples to serum to confirm HPV vaccine antibody status. A study was carried out to evaluate the feasibility of detecting HPV16 and HPV18 antibodies in OMT, DBSs, and sera among women who self-reported being unvaccinated or fully vaccinated with the HPV vaccine...
June 27, 2018: MSphere
https://www.readbyqxmd.com/read/29742760/functioning-in-women-with-cervical-cancer-in-brazil-the-perspective-of-experts
#17
Luciana Castaneda, Anke Bergmann, Shamyr Castro, Rosalina Koifman
OBJECTIVE:  The objective of this study was to identify the perspective of the specialists about functioning in women with cervical cancer (CC). METHODS:  A study was conducted with specialists using the Delphi methodology. The specialist contacts were found in oncology organizations and associations, as well as in a referral hospital in the treatment of CC. The questions that the experts answered covered the biopsychosocial domains of the International Classification of Functioning, Disability and Health (ICF)...
May 9, 2018: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29742008/sex-body-image-and-relationships-a-brightlight-workshop-on-information-and-support-needs-of-adolescents-and-young-adults
#18
Ana Martins, Rachel M Taylor, Brian Lobel, Beth McCann, Louise Soanes, Jeremy S Whelan, Lorna A Fern
PURPOSE: Discovering sexuality and romantic relationships are important development milestones in adolescence and young adulthood. A cancer diagnosis imposes obstacles for young people such as changes in their sexual function due to the disease and/or side effects of treatment, body image concerns, and interpersonal relationship difficulties. This can cause psychological distress and can impact on quality of life. We aimed to explore sexual health information and support needs of adolescents and young adults with cancer...
May 9, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29741607/modeling-recovery-curves-with-application-to-prostatectomy
#19
Fulton Wang, Cynthia Rudin, Tyler H Mccormick, John L Gore
In many clinical settings, a patient outcome takes the form of a scalar time series with a recovery curve shape, which is characterized by a sharp drop due to a disruptive event (e.g., surgery) and subsequent monotonic smooth rise towards an asymptotic level not exceeding the pre-event value. We propose a Bayesian model that predicts recovery curves based on information available before the disruptive event. A recovery curve of interest is the quantified sexual function of prostate cancer patients after prostatectomy surgery...
May 5, 2018: Biostatistics
https://www.readbyqxmd.com/read/29740782/quality-of-life-problems-and-needs-of-disease-free-breast-cancer-survivors-5-years-after-diagnosis
#20
Martina E Schmidt, Joachim Wiskemann, Karen Steindorf
PURPOSE: After cancer treatment, it is desirable to maintain or regain a high quality of life (QoL) and the ability to accomplish everyday tasks well. Therefore, we substantiated the scarce knowledge regarding long-term QoL after breast cancer, burdensome problems, and unmet needs for more support. METHODS: Disease-free breast cancer survivors (n = 190) who had participated in two randomized controlled exercise trials during primary treatment were followed up to 5 years post-diagnosis...
May 8, 2018: Quality of Life Research
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