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Stroke in young age

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https://www.readbyqxmd.com/read/28427162/effect-of-age-on-long-term-outcomes-after-stroke-with-atrial-fibrillation-a-hospital-based-follow-up-study-in-china
#1
Tao Wang, Bin Li, Hongfei Gu, Yongzhong Lou, Xianjia Ning, Jinghua Wang, Zhongping An
Atrial fibrillation (AF) is an established predictor of poor outcomes after stroke. We aimed to assess the effect of age on outcomes at 1 year and 3 years in stroke patients with AF.We recruited acute ischemic stroke patients with AF between January 2006 and September 2014 in Tianjin, China. Clinical features and outcomes at 1 year and 3 years after stroke were compared between younger group and elderly group. Overall, 951 consecutive stroke patients with AF were included in this study. There was a higher mortality and dependency rate in the elderly group than in the young group at both 1 and 3 years after stroke...
February 25, 2017: Oncotarget
https://www.readbyqxmd.com/read/28420049/the-spectrum-of-neuropsychiatric-lupus-in-a-black-caribbean-population-a-report-of-the-barbados-national-lupus-registry
#2
C Flower, I Hambleton, D Corbin, S Marquez, R Edghill
Objective The objective of this study was to examine neuropsychiatric lupus in a Black Caribbean population. Methods We reviewed Barbados National Lupus Registry patients with ≥4 American College of Rheumatology criteria and a diagnosis of neuropsychiatric lupus using the American College of Rheumatology 19 case definitions. Results From 366 patients with four or more American College of Rheumatology criteria for systemic lupus erythematosus, 55 (15%) had evidence of neuropsychiatric lupus. There were 51 females and four males (F:M = 13:1) with a median age of 31 years...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28413184/risk-of-ischemic-stroke-in-patients-with-non-valvular-atrial-fibrillation-not-receiving-oral-anticoagulants%C3%A3-korean-nationwide-population-based-study
#3
Si-Hyuck Kang, Eue-Keun Choi, Kyung-Do Han, So-Ryoung Lee, Woo-Hyun Lim, Myung-Jin Cha, Youngjin Cho, Il-Young Oh, Seil Oh
BACKGROUND: Atrial fibrillation, the most common cardiac arrhythmia, is associated with an elevated thromboembolic risk, including ischemic stroke. Guidelines recommend the stratification of individual stroke risk and tailored antithrombotic therapy. This study investigated the demographics, comorbidities, and prognosis of non-valvular AF (NVAF) in Korean patients.Methods and Results:We extracted data on 10,846 patients with newly diagnosed NVAF who were naïve to oral anticoagulants from the National Health Insurance Service-National Sample Cohort...
April 12, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28412319/genetic-and-non-genetic-factors-affecting-the-quality-of-anticoagulation-control-and-vascular-events-in-atrial-fibrillation
#4
Yun Kyung Park, Mi Ji Lee, Jae Ha Kim, Jin Soo Lee, Rae Woong Park, Gyeong-Moon Kim, Chin-Sang Chung, Kwang Ho Lee, June Soo Kim, Soo-Youn Lee, Oh Young Bang
BACKGROUND: Warfarin has a narrow therapeutic window. We hypothesized that genetic factors related to warfarin metabolism (CYP2C9) and activity (VKORC1) would show stronger associations than modifiable factors with the quality of anticoagulation control and risks for thromboembolism and hemorrhage. METHODS: In this retrospective cohort analysis, clinical and genetic data were collected from 380 patients with atrial fibrillation (AF) who were followed for an average observation period of 4 years...
April 12, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28408257/ischemic-stroke-in-young-adults-with-moyamoya-disease-prognostic-factors-for-stroke-recurrence-and-functional-outcome-after-revascularization
#5
Meng Zhao, Xiaofeng Deng, Faliang Gao, Dong Zhang, Shuo Wang, Yan Zhang, Rong Wang, Jizong Zhao
OBJECTIVE: Stroke in young adults is uncommon and have rarely been described. Moyamoya disease is one of the leading causes of stroke in young adults. We aimed to study the prognostic factors for stroke recurrences and functional outcomes in young stroke patients with moyamoya disease after revascularization. METHODS: We reviewed 696 consecutive patients with moyamoya disease admitted to our hospital from 2009 to 2015 and identified patients aged 18-45 years with first-ever stroke...
April 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28407021/analysis-of-the-prevalence-and-associated-factors-of-overactive-bladder-in-adult-korean-men
#6
So Young Kim, Woojin Bang, Hyo Geun Choi
Overactive bladder (OAB) is a prevalent condition characterized by lower urinary tract symptoms (LUTS). Age, education, income, marital status, sleep, and emotional problems have been associated with OAB; however, conflicting results exist. The present study was conducted to estimate the prevalence of OAB and comprehensively analyze its associated factors in a large cross-sectional, population-based study. The data of 94,554 participants aged 19-107 were analyzed from the Korean Community Health Survey (KCHS) of 2012...
2017: PloS One
https://www.readbyqxmd.com/read/28406586/total-cerebral-small-vessel-disease-score-is-associated-with-mortality-during-follow-up-after-acute-ischemic-stroke
#7
Tae Jin Song, Jinkwon Kim, Dongbeom Song, Joonsang Yoo, Hye Sun Lee, Yong Jae Kim, Hyo Suk Nam, Ji Hoe Heo, Young Dae Kim
BACKGROUND AND PURPOSE: The recently developed total cerebral small-vessel disease (CSVD) score might appropriately reflect the total burden or severity of CSVD. We investigated whether the total CSVD score is associated with long-term outcomes during follow-up in patients with acute ischemic stroke. METHODS: In total, 1,096 consecutive patients with acute ischemic stroke who underwent brain magnetic resonance imaging were enrolled. We calculated the total CSVD score for each patient after determining the burden of cerebral microbleeds (CMBs), high-grade white-matter hyperintensities (HWHs), high-grade perivascular spaces (HPVSs), and asymptomatic lacunar infarctions (ALIs)...
April 2017: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/28400903/neurosarcoidosis-presenting-with-recurrent-strokes-a-case-report-and-literature-review
#8
Naheed Raza, Karisa C Schreck
Neurosarcoidosis is a rare but important cause of stroke as it is treatable. Cases reported thus far have primarily been in young people who are relatively healthy. Here we report the case of a 73-year-old woman presenting with recurrent strokes and high-grade intracranial stenosis caused by probable neurosarcoidosis. This is unique as neurosarcoidosis is not usually considered as an etiology for recurrent strokes in our patient's age-group. We review and categorize published cases of neurosarcoidosis causing stroke and describe a classification scheme for certainty of diagnosis...
April 2017: Neurohospitalist
https://www.readbyqxmd.com/read/28395017/prevalence-of-cardiovascular-risk-factors-and-strokes-in-younger-adults
#9
Mary G George, Xin Tong, Barbara A Bowman
Importance: While stroke mortality rates have decreased substantially in the past 2 decades, this trend has been primarily limited to older adults. Increasing trends in stroke incidence and hospitalizations have been noted among younger adults, but there has been concern that this reflected improved diagnosis through an increased use of imaging rather than representing a real increase. Objectives: To determine whether stroke hospitalization rates have continued to increase and to identify the prevalence of associated stroke risk factors among younger adults...
April 10, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28390402/an-analysis-of-depressive-symptoms-in-stroke-survivors-verification-of-a-moderating-effect-of-demographic-characteristics
#10
Eun-Young Park, Jung-Hee Kim
BACKGROUND: The rehabilitation of depressed stroke patients is more difficult because poststroke depression is associated with disruption of daily activities, functioning, and quality of life. However, research on depression in stroke patients is limited. The aim of our study was to evaluate the interaction of demographic characteristics including gender, age, education level, the presence of a spouse, and income status on depressive symptoms in stroke patients and to identify groups that may need more attention with respect to depressive symptoms...
April 8, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28389240/association-of-exercise-and-metabolic-equivalent-of-task-met-score-with-survival-outcomes-after-out-of-hospital-cardiac-arrest-of-young-and-middle-age
#11
Young Sun Ro, Sang Do Shin, Kyoung Jun Song, Ki Jeong Hong, Ki Ok Ahn
BACKGROUND: Regular physical activity is recommended to prevent cardiovascular disease including out-of-hospital cardiac arrest (OHCA). However, it is uncertain whether the intensity during physical activity is associated with better outcomes. We studied the effect of exercise at the time of arrest and the association between metabolic equivalent of task (MET) score and survival of OHCA patients of young and middle age. METHODS: All OHCAs of presumed cardiac etiology who were 18-65 years of age and were witnessed by a layperson between 2013 and 2015 were analyzed...
April 4, 2017: Resuscitation
https://www.readbyqxmd.com/read/28381999/cognitive-processing-speed-across-the-lifespan-beyond-the-influence-of-motor-speed
#12
Deena Ebaid, Sheila G Crewther, Kirsty MacCalman, Alyse Brown, Daniel P Crewther
Traditional neuropsychological measurement of cognitive processing speed with tasks such as the Symbol Search and Coding subsets of the WAIS-IV, consistently show decline with advancing age. This is potentially problematic with populations where deficits in motor performance are expected, i.e., in aging or stroke populations. Thus, the aim of the current study was to explore the contribution of hand motor speed to traditional paper-and-pencil measures of processing speed and to a simple computer-customized non-motor perception decision task, the Inspection Time (IT) task...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28380324/a-15-year-epileptogenic-period-after-perinatal-brain-injury
#13
F Pisani, E Pavlidis, C Facini, C La Morgia, C Fusco, G Cantalupo
Seizures are a frequent acute neurological event in the neonatal period. Up to 12 to 18% of all seizures in newborns are due to perinatal stroke and up to 39% of affected children can then develop epilepsy in childhood. We report the case of a young patient who presented stroke-related seizures in the neonatal period and then developed focal symptomatic epilepsy at 15 years of age, and in whom the epileptic focus was found to co-localize with the site of his ischemic brain lesion. Such a prolonged silent period before onset of remote symptomatic epilepsy has not previously been reported...
January 2017: Functional Neurology
https://www.readbyqxmd.com/read/28372902/prognostic-value-of-peripheral-leukocyte-counts-and-plasma-glucose-in-intracerebral-haemorrhage
#14
S Kayhanian, C K Weerasuriya, U Rai, A M H Young
INTRODUCTION: The value of routine blood markers as prognostic indicators is increasingly established in acute ischaemic stroke. The relationship is less well defined in haemorrhagic stroke. In this study, we examined routine admission blood markers and applied a logistic regression model to predict outcome in haemorrhagic stroke. METHOD: A retrospective study was performed between September 2009-2011 in a general admission stroke unit in the UK. 1400 patients were admitted with stroke during this period, of which 117 were haemorrhagic...
March 31, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28372804/changing-trends-of-atherosclerotic-risk-factors-among-patients-with-acute-myocardial-infarction-and-acute-ischemic-stroke
#15
Shikhar Agarwal, Karan Sud, Badal Thakkar, Venu Menon, Wael A Jaber, Samir R Kapadia
We aimed to evaluate the secular trends in demographics, risk factors, and clinical characteristics of patients presenting with acute myocardial infarction (AMI) or acute ischemic stroke (AIS), using a large nationally representative data set of in-hospital admissions. We used the 2003 to 2013 Nationwide Inpatient Sample. All admissions with primary diagnosis of AMI or AIS were included. Across 2003 to 2013, a total of 1,360,660 patients with AMI and 937,425 patients with AIS were included in the study. We noted a progressive reduction in the mean age of patients presenting with AMI and AIS (p trend <0...
March 31, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28368898/the-effect-of-sleep-disturbances-on-the-functional-recovery-of-rehabilitation-inpatients-following-mild-and-moderate-stroke
#16
Kyung-Lim Joa, Won-Hyoung Kim, Ha-Yoon Choi, Chan-Hyuk Park, Eun-Suk Kim, Sook-Joung Lee, Soo-Yeon Kim, Sung-Hwa Ko, Han-Young Jung
OBJECTIVE: The aim of the study was to explore the impact of insomnia and sleep disturbance on the functional outcomes of mild and moderated stroke. DESIGN: A multicenter-observational and correlation study was performed. Two hundred eighty patients with mild-moderate severity stroke admitted to three acute hospitals rehabilitation departments. Diagnostic Statistical Manual of Mental Disorders, Fourth Edition, criteria were used to define patients with insomnia and any sleep disturbance...
March 31, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28356037/markers-of-early-vascular-ageing
#17
Vasilios Kotsis, Christina Antza, Ioannis Doundoulakis, Stella Stabouli
BACKGROUND: Cardiovascular damage is clinically manifested as coronary artery disease, heart failure, stroke and peripheral artery disease. The prevalence of these adverse conditions is higher with advancing age. Although many patients present cardiovascular damage late in their life, it is common to see patients with early atherosclerosis in cardiovascular intensive care units at ages lower than 50 years in men and 55 for women. METHODS AND RESULTS: In this review of the literature we identified risk factors of early vascular damage...
March 28, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28355959/does-national-expenditure-on-research-and-development-influence-stroke-outcomes
#18
Young Dae Kim, Yo Han Jung, Bo Norrving, Bruce Ovbiagele, Gustavo Saposnik
Background Expenditure on research and development is a macroeconomic indicator representative of national investment. International organizations use this indicator to compare international research and development activities. Aim We investigated whether differences in expenditures on research and development at the country level may influence the incidence of stroke and stroke mortality. Methods We compared stroke metrics with absolute amount of gross domestic expenditure on R&D (GERD) per-capita adjusted for purchasing power parity (aGERD) and relative amount of GERD as percent of gross domestic product (rGERD)...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/28355718/-the-clinical-characteristics-of-stroke-in-young-patients-with-cardiac-myxoma
#19
G F Cao, Q Bi, L Cao, C Wang
Objective: To investigate the clinical characteristics of stroke in young patients with cardiac myxoma. Methods: Medical records of young patients (aged between 18-44 years) diagnosed with cardiac myxoma in Beijing Anzhen Hospital affiliated to Capital Medical University from January 2005 to March 2016 were retrospective reviewed. Results: A total of 117 cases were included (85 female and 32 male)with the average age (36±7)years old. Most myxomas (83.8%) were located in the left atrium, 7.7% were in the right atrium, 3...
April 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/28350246/frequency-presentation-and-outcome-of-takayasu-arteritis-in-western-australia
#20
Krista Makin, Maxine Isbel, Johannes Nossent
OBJECTIVES: Takayasu arteritis (TAK) is large-vessel vasculitis that predominantly affects young women. There is worldwide variation in the frequency of TAK depending on genetic and/or environmental factors. With Australian data lacking, we describe the epidemiology, clinical features and outcomes of TAK in Western Australia (WA). METHODS: Retrospective case cohort study of incident TAK cases between 1 January 2000 and 30 June 2015 in WA identified from multiple sources...
March 28, 2017: Modern Rheumatology
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