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https://www.readbyqxmd.com/read/29145709/defining-a-unified-vascular-phenotype-in-systemic-sclerosis
#1
REVIEW
Yannick Allanore, Oliver Distler, Marco Matucci-Cerinic, Christopher P Denton
Microcirculation impairment and related vasculopathy is a hallmark of systemic sclerosis. Digital ulcers are second only to Raynaud's phenomenon as a vascular complication occurring in scleroderma patients. Digital ulcers are painful and generate disability. Furthermore, patients may develop recurrent digital ulcers and one may ask whether the outcomes of such patients might be different to those of unaffected ones. Recently several registries have provided relevant information about digital ulcers. Male sex and severe skin disease seem to be the main associated factors observed in several registries...
November 16, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29145557/comparative-analysis-of-the-growth-pattern-of-thyroid-cancer-in-young-patients-screened-by-ultrasonography-in-japan-after-a-nuclear-accident-the-fukushima-health-management-survey
#2
Sanae Midorikawa, Akira Ohtsuru, Michio Murakami, Hideto Takahashi, Satoru Suzuki, Takashi Matsuzuka, Hiroki Shimura, Tetsuya Ohira, Shin-Ichi Suzuki, Seiji Yasumura, Shunichi Yamashita, Hitoshi Ohto, Koichi Tanigawa, Kenji Kamiya
Importance: Thyroid cancer generally grows at a very slow rate in adults, and overdiagnosis is a global issue. However, the detection of early-stage thyroid cancer by screening is not well described in young patients. To prevent overdiagnosis, it is essential to understand the natural course of thyroid cancer growth detection by ultrasonography screening in young patients. Objective: To evaluate the natural progression of thyroid cancer in young patients. Design, Setting, and Participants: An observational study evaluated changes in the diameter of malignant or suspected malignant thyroid tumors on 2 occasions...
November 16, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29145516/preconceptual-zika-virus-asymptomatic-infection-protects-against-secondary-prenatal-infection
#3
Lucien H Turner, Jeremy M Kinder, Adrienne Wilburn, Rahul J D'Mello, Makayla R Braunlin, Tony T Jiang, Giang Pham, Sing Sing Way
Pregnant women, and their fetal offspring, are uniquely susceptible to Zika virus and other microbial pathogens capable of congenital fetal infection. Unavoidable exposure to Zika virus in endemic areas underscores the need for identifying at-risk individuals, and protecting expecting mothers and their fetal offspring against prenatal infection. Here we show that primary Zika virus asymptomatic infection in mice confers protection against re-infection, and that these protective benefits are maintained during pregnancy...
November 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/29145475/mapping-three-dimensional-surface-deformation-caused-by-the-2010-haiti-earthquake-using-advanced-satellite-radar-interferometry
#4
Hyung-Sup Jung, Soo-Min Hong
Mapping three-dimensional (3D) surface deformation caused by an earthquake is very important for the environmental, cultural, economic and social sustainability of human beings. Synthetic aperture radar (SAR) systems made it possible to measure precise 3D deformations by combining SAR interferometry (InSAR) and multiple aperture interferometry (MAI). In this paper, we retrieve the 3D surface deformation field of the 2010 Haiti earthquake which occurred on January 12, 2010 by a magnitude 7.0 Mw by using the advanced interferometric technique that integrates InSAR and MAI data...
2017: PloS One
https://www.readbyqxmd.com/read/29145459/the-construction-of-ventilation-turrets-in-atta-vollenweideri-leaf-cutting-ants-carbon-dioxide-levels-in-the-nest-tunnels-but-not-airflow-or-air-humidity-influence-turret-structure
#5
Florian Halboth, Flavio Roces
Nest ventilation in the leaf-cutting ant Atta vollenweideri is driven via a wind-induced mechanism. On their nests, workers construct small turrets that are expected to facilitate nest ventilation. We hypothesized that the construction and structural features of the turrets would depend on the colony's current demands for ventilation and thus might be influenced by the prevailing environmental conditions inside the nest. Therefore, we tested whether climate-related parameters, namely airflow, air humidity and CO2 levels in the outflowing nest air influenced turret construction in Atta vollenweideri...
2017: PloS One
https://www.readbyqxmd.com/read/29145438/factors-associated-with-patients-satisfaction-in-brazilian-dental-primary-health-care
#6
Muath Abdullah Aldosari, Mary Angela Tavares, Antônio Thomaz Gonzaga Matta-Machado, Mauro Henrique Nogueira Guimarães Abreu
OBJECTIVE: To assess factors associated with patients' satisfaction with the treatment by dentists in primary health care (PHC) in Brazil. MATERIALS AND METHODS: The dataset was part of a nationwide cross-sectional survey for evaluating PHC teams conducted by the Brazilian Ministry of Health. Patients from each of 16,202 oral health teams were interviewed. In addition to sociodemographic information, the questionnaire included information about patient experience domains: access and booking of dental appointments, bonding and accountability, welcoming of the patient, and their perception of dental facilities...
2017: PloS One
https://www.readbyqxmd.com/read/29145397/post-kala-azar-dermal-leishmaniasis-in-the-indian-subcontinent-a-threat-to-the-south-east-asia-region-kala-azar-elimination-programme
#7
REVIEW
Eduard E Zijlstra, Fabiana Alves, Suman Rijal, Byron Arana, Jorge Alvar
BACKGROUND: The South-East Asia Region Kala-azar Elimination Programme (KAEP) is expected to enter the consolidation phase in 2017, which focuses on case detection, vector control, and identifying potential sources of infection. Post-kala-azar dermal leishmaniasis (PKDL) is thought to play a role in the recurrence of visceral leishmaniasis (VL)/kala-azar outbreaks, and control of PKDL is among the priorities of the KAEP. METHODOLOGY AND PRINCIPAL FINDING: We reviewed the literature with regard to PKDL in Asia and interpreted the findings in relation to current intervention methods in the KAEP in order to make recommendations...
November 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29145346/role-of-delayed-time-point-imaging-during-abdominal-and-pelvic-cancer-screening-using-fdg-pet-ct-in-the-general-population
#8
Shotaro Naganawa, Takeharu Yoshikawa, Koichiro Yasaka, Eriko Maeda, Naoto Hayashi, Osamu Abe
Although delayed-time-point imaging is expected to improve the results of [F]-fluorodeoxyglucose (FDG)-positron emission tomography/computed tomography (PET/CT), how examinees will benefit from dual-time-point imaging versus initial-time-point imaging alone, remains unclear. This study investigated the role of delayed-time-point imaging in improving the results of abdominal and pelvic cancer screening using FDG-PET/CT.This retrospective review included 3131 screening results (average subject age: 55.5 years, range: 40-88 years)...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145327/current-practice-and-usual-care-of-major-cervical-disorders-in-korea-a-cross-sectional-study-of-korean-health-insurance-review-and-assessment-service-national-patient-sample-data
#9
A Ryeon Choi, Joon-Shik Shin, Jinho Lee, Yoon Jae Lee, Me-Riong Kim, Min-Seok Oh, Eun-Jung Lee, Sungchul Kim, Mia Kim, In-Hyuk Ha
Neck pain is a highly common condition and is the 4th major cause of years lived with disability. Previous literature has focused on the effect of specific treatments, and observations of actual practice are lacking to date. This study examined Korean health insurance review and assessment service (HIRA) claims data to the aim of assessing prevalence and comparing current medical practice and costs of cervical disorders in Korea.Current practice trends were determined through assessment of prevalence, total expenses, per-patient expense, average days in care, average days of visits, sociodemographic characteristics, distribution of medical costs, and frequency of treatment types of high frequency cervical disorders (cervical sprain/strain, cervical intervertebral disc displacement [IDD], and cervicalgia)...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145300/cost-effectiveness-analysis-of-neonatal-screening-of-critical-congenital-heart-defects-in-china
#10
Ruoyan Gai Tobe, Gerard R Martin, Fuhai Li, Akinori Moriichi, Bin Wu, Rintaro Mori
BACKGROUND: Pulse oximetry screening is a highly accurate tool for the early detection of critical congenital heart disease (CCHD) in newborn infants. As the technique is simple, noninvasive, and inexpensive, it has potentially significant benefits for developing countries. The aim of this study is to provide information for future clinical and health policy decisions by assessing the cost-effectiveness of CCHD screening in China. METHODS AND FINDINGS: We developed a cohort model to evaluate the cost-effectiveness of screening all Chinese newborns annually using 3 possible screening options compared to no intervention: pulse oximetry alone, clinical assessment alone, and pulse oximetry as an adjunct to clinical assessment...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145100/environmental-assessment-of-microwaves-and-the-effect-of-european-energy-efficiency-and-waste-management-legislation
#11
Alejandro Gallego-Schmid, Joan Manuel F Mendoza, Adisa Azapagic
More than 130 million microwaves are affected by European Union (EU) legislation which is aimed at reducing the consumption of electricity in the standby mode ('Standby Regulation') and at more sustainable management of end-of-life electrical and electronic waste ('WEEE Directive'). While legislation focuses on these two life cycle stages, there is little information on the environmental impacts of the entire life cycle of microwaves. To address this gap, this paper presents a comprehensive life cycle assessment of microwaves and assesses the environmental implications of the Standby Regulation and the WEEE Directive at the EU level...
November 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29145086/active-learning-for-classifying-data-streams-with-unknown-number-of-classes
#12
Saad Mohamad, Moamar Sayed-Mouchaweh, Abdelhamid Bouchachia
The classification of data streams is an interesting but also a challenging problem. A data stream may grow infinitely making it impractical for storage prior to processing and classification. Due to its dynamic nature, the underlying distribution of the data stream may change over time resulting in the so-called concept drift or the possible emergence and fading of classes, known as concept evolution. In addition, acquiring labels of data samples in a stream is admittedly expensive if not infeasible at all...
October 27, 2017: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/29145075/isolation-and-characterisation-of-an-unexpected-byproduct-in-the-regioselective-butane-diacetal-protection-of-%C3%AE-methyl-galactopyranoside
#13
Clément Q Fontenelle, Ramakrishna Kuppala, Mark Light, Bruno Linclau
The regioselective protection of both methyl galactopyranoside anomers at the 2 and 3-positions as the butane diacetal (BDA) is well known. Here we describe the formation of an unexpected byproduct, which mainly occurs when α-methyl galactopyranoside is reacted with 2,3-butanedione under BF3•OEt2 catalysis. The structure of the byproduct, which did not arise from anomerisation to the β-anomer or from BDA formation at the galactopyranoside 3,4-positions, was elucidated by NMR and X-ray crystallographic analysis, and proved to be the expected BDA protected galactopyranoside, but in which the stereochemistry of both its BDA acetal centres are inverted...
November 6, 2017: Carbohydrate Research
https://www.readbyqxmd.com/read/29145020/evaluation-of-7-be-and-133-xe-atmospheric-radioactivity-time-series-measured-at-four-ctbto-radionuclide-stations
#14
Stefano Bianchi, Alessandro Longo, Wolfango Plastino, Pavel P Povinec
Time series analysis of (7)Be and (133)Xe atmospheric data and meteorological parameters measured at four CTBTO/IMS radionuclide stations have shown great variability in terms of noise structures, harmonic content, cross-correlation patterns and local Hurst exponent behaviour. This study focused on highlighting and characterising both differences and similarities expected for these radionuclides due to their different physical and chemical characteristics along with their different source terms. Detrended crosscorrelation analysis of different meteorological parameters influencing the residuals time series has shown that for Canadian and American stations the parameters mostly affecting radionuclide concentrations in the air seem to be wind direction and atmospheric pressure...
November 2, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/29144997/examination-of-a-therapeutic-recreation-based-clinical-placement-for-undergraduate-nursing-students-a-self-determined-perspective
#15
Dana Perlman, Ellie Taylor, Lorna Moxham, Susan Sumskis, Christopher Patterson, Renee Brighton, Tim Heffernan
Nursing students across the globe are expected to undertake clinical placements. To date, there have been no studies that have examined the potential educational benefits for undergraduate nursing students engaged in a mental health clinical placement grounded in self-determination theory. The present study examined the experiences of undergraduate students engaged in a mental health clinical placement termed Recovery Camp. An ethnographic methodology within a case study approach was used. The researchers were immersed in the clinical placement, which took place at a YMCA camp facility...
November 10, 2017: Nurse Education in Practice
https://www.readbyqxmd.com/read/29144981/barriers-to-self-compassion-for-female-survivors-of-childhood-maltreatment-the-roles-of-fear-of-self-compassion-and-psychological-inflexibility
#16
Derrecka M Boykin, Sara J Himmerich, Caitlin M Pinciotti, Lindsay M Miller, Lynsey R Miron, Holly K Orcutt
Preliminary evidence has demonstrated the benefits of targeting self-compassion in the treatment of posttraumatic stress disorder (PTSD). However, survivors of childhood maltreatment may present with unique challenges that compromise the effectiveness of these and other PTSD treatments. Specifically, childhood maltreatment victims often exhibit a marked fear and active resistance of self-kindness and warmth (i.e., fear of self-compassion). Victims may also attempt to control distressing internal experiences in a way that hinders engagement in value-based actions (i...
November 13, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29144977/birthplace-in-australia-processes-and-interactions-during-the-intrapartum-transfer-of-women-from-planned-homebirth-to-hospital
#17
Deborah Fox, Athena Sheehan, Caroline Homer
OBJECTIVE: the aim of the study was to explore the views and experiences of women, midwives and obstetricians on the intrapartum transfer of women from planned homebirth to hospital in Australia. DESIGN: a Constructivist Grounded Theory approach was taken, to conceptualise the social interactions and processes grounded in the data. SETTING: urban and regional areas in four states of south-eastern Australia. PARTICIPANTS: semi-structured qualitative interviews were conducted with 36 women, midwives and obstetricians who had experienced an intrapartum homebirth transfer within three years prior to the interview...
November 2, 2017: Midwifery
https://www.readbyqxmd.com/read/29144847/explaining-the-sexuality-gap-in-protest-participation
#18
Eric Swank
This study investigated the relationship between sexual orientations and the protest actions of adults in the United States. Drawing from General Social Survey data from 1996 to 2004, we found that lesbians, gays, and bisexuals were more than twice as likely to protest as heterosexuals. To account for this sexuality gap, we used Patrick Egan's (2008) political distinctiveness theories to identify possible underlying causes of these protesting differences. After running several regressions, we found that sexuality and protesting relationships were moderated by issues of educational attainment, marital statuses, metropolitan residencies, political partisanships, governmental grievances, and gender role expectations...
November 16, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/29144838/human-t-cell-leukemia-virus-type-1-persistence-and-pathogenesis
#19
Charles R M Bangham
Human T cell leukemia virus type 1 (HTLV-1), also known as human T lymphotropic virus type 1, was the first exogenous human retrovirus discovered. Unlike the distantly related lentivirus HIV-1, HTLV-1 causes disease in only 5-10% of infected people, depending on their ethnic origin. But whereas HIV-1 infection and the consequent diseases can be efficiently contained in most cases by antiretroviral drug treatment, there is no satisfactory treatment for the malignant or inflammatory diseases caused by HTLV-1...
November 16, 2017: Annual Review of Immunology
https://www.readbyqxmd.com/read/29144837/evolution-of-alternative-adaptive-immune-systems-in-vertebrates
#20
Thomas Boehm, Masayuki Hirano, Stephen J Holland, Sabyasachi Das, Michael Schorpp, Max D Cooper
Adaptive immunity in jawless fishes is based on antigen recognition by three types of variable lymphocyte receptors (VLRs) composed of variable leucinerich repeats, which are differentially expressed by two T-like lymphocyte lineages and one B-like lymphocyte lineage. The T-like cells express either VLRAs or VLRCs of yet undefined antigen specificity, whereas the VLRB antibodies secreted by B-like cells bind proteinaceous and carbohydrate antigens. The incomplete VLR germline genes are assembled into functional units by a gene conversion-like mechanism that employs flanking variable leucine-rich repeat sequences as templates in association with lineage-specific expression of cytidine deaminases...
November 16, 2017: Annual Review of Immunology
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