keyword
MENU ▼
Read by QxMD icon Read
search

caudal forelimb area

keyword
https://www.readbyqxmd.com/read/27864839/reduction-of-the-foreign-body-response-and-neuroprotection-by-apyrase-and-minocycline-in-chronic-cannula-implantation-in-the-rat-brain
#1
Linda Hayn, Linda Deppermann, Michael Koch
Implantation of electrodes or cannulae into the brain is accompanied by a tissue response referred to as foreign body response. Adenosine triphosphate (ATP) is one of the signalling molecules released by injured cells which mediate the chemoattraction of microglial cells. The constitutive release of pro-inflammatory and cytotoxic substances by microglial cells in chronic implants exacerbates neuronal cell death and the immune response. This study aimed to interfere with the initial events of the foreign body response in order to mitigate neurotoxicity and inflammation...
November 19, 2016: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/27743923/the-role-of-endogenous-neurogenesis-in-functional-recovery-and-motor-map-reorganization-induced-by-rehabilitative-therapy-after-stroke-in-rats
#2
Takashi Shiromoto, Naohiko Okabe, Feng Lu, Emi Maruyama-Nakamura, Naoyuki Himi, Kazuhiko Narita, Yoshiki Yagita, Kazumi Kimura, Osamu Miyamoto
BACKGROUND AND OBJECTIVE: Endogenous neurogenesis is associated with functional recovery after stroke, but the roles it plays in such recovery processes are unknown. This study aims to clarify the roles of endogenous neurogenesis in functional recovery and motor map reorganization induced by rehabilitative therapy after stroke by using a rat model of cerebral ischemia (CI). METHODS: Ischemia was induced via photothrombosis in the caudal forelimb area of the rat cortex...
October 12, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27725217/neural-network-remodeling-underlying-motor-map-reorganization-induced-by-rehabilitative-training-after-ischemic-stroke
#3
Naohiko Okabe, Takashi Shiromoto, Naoyuki Himi, Feng Lu, Emi Maruyama-Nakamura, Kazuhiko Narita, Nobuhisa Iwachidou, Yoshiki Yagita, Osamu Miyamoto
Motor map reorganization is believed to be one mechanism underlying rehabilitation-induced functional recovery. Although the ipsilesional secondary motor area has been known to reorganize motor maps and contribute to rehabilitation-induced functional recovery, it is unknown how the secondary motor area is reorganized by rehabilitative training. In the present study, using skilled forelimb reaching tasks, we investigated neural network remodeling in the rat rostral forelimb area (RFA) of the secondary motor area during 4weeks of rehabilitative training...
December 17, 2016: Neuroscience
https://www.readbyqxmd.com/read/27717064/high-order-motor-cortex-in-rats-receives-somatosensory-inputs-from-the-primary-motor-cortex-via-cortico-cortical-pathways
#4
Nobuo Kunori, Ichiro Takashima
The motor cortex of rats contains two forelimb motor areas; the caudal forelimb area (CFA) and the rostral forelimb area (RFA). Although the RFA is thought to correspond to the premotor and/or supplementary motor cortices of primates, which are higher-order motor areas that receive somatosensory inputs, it is unknown whether the RFA of rats receives somatosensory inputs in the same manner. To investigate this issue, voltage-sensitive dye (VSD) imaging was used to assess the motor cortex in rats following a brief electrical stimulation of the forelimb...
October 7, 2016: European Journal of Neuroscience
https://www.readbyqxmd.com/read/27488936/large-scale-analysis-reveals-populational-contributions-of-cortical-spike-rate-and-synchrony-to-behavioral-functions
#5
Rie Kimura, Akiko Saiki, Yoko Fujiwara-Tsukamoto, Yutaka Sakai, Yoshikazu Isomura
Spike synchrony within several milliseconds in presynaptic neurons enables effective integration of functional information in the postsynaptic neuron. However, few studies have systematically analyzed the population-wide relationships between spike synchrony and behavioral functions. Here we obtained a sufficiently large amount of spike data among regular-spiking (RS; putatively excitatory) and fast-spiking (FS; putatively inhibitory) neuron subtypes (>23,000 pairs) by multiple single-unit recording from deep layers in motor cortical areas [caudal forelimb area (CFA), rostral forelimb area (RFA)] in rats performing a forelimb movement task...
August 4, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27487657/-the-distribution-of-cortico-thalamic-projections-of-different-of-different-somatotopic-representations-of-primary-motor-and-sensory-cortex
#6
N M Ipekchyan, S A Badalyan
The peculiarities of localization and distribution of cortico-thalamic efferents of different somatotopical representations of primary motor (MI) and sensory (SI) cortex were studied in cat brain. MI efferent fibers (4y, 6ab areas) preferentially projected to ventral posterolateral and medial (VPL, VPM), ventrolateral (VL), and reticular (R) nuclei, localized in rostral part of the thalamus (T), as opposed to SI (areas 1, 2, 3a, 3b), which projected preferentially to caudal part of T, VPL, VPM and R nuclei...
2016: Morfologi︠a︡
https://www.readbyqxmd.com/read/27037503/ipsilateral-cortical-inputs-to-the-rostral-and-caudal-motor-areas-in-rats
#7
Hisham Mohammed, Neeraj Jain
Rats have a complete body representation in the primary motor cortex (M1). Rostrally there are additional representations of the forelimb and whiskers, called the rostral forelimb area (RFA) and the rostral whisker area (RWA). Recently we showed that sources of thalamic inputs to RFA and RWA are similar, but they are different from those for the caudal forelimb area (CFA) and the caudal whisker area (CWA) of M1 (Mohammed and Jain [2014] J Comp Neurol 522:528-545). We proposed that RWA and RFA are part of a second motor area, the rostral motor area (RMA)...
October 15, 2016: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/26937002/corticospinal-inputs-to-primate-motoneurons-innervating-the-forelimb-from-two-divisions-of-primary-motor-cortex-and-area-3a
#8
Claire L Witham, Karen M Fisher, Steve A Edgley, Stuart N Baker
UNLABELLED: Previous anatomical work in primates has suggested that only corticospinal axons originating in caudal primary motor cortex ("new M1") and area 3a make monosynaptic cortico-motoneuronal connections with limb motoneurons. By contrast, the more rostral "old M1" is proposed to control motoneurons disynaptically via spinal interneurons. In six macaque monkeys, we examined the effects from focal stimulation within old and new M1 and area 3a on 135 antidromically identified motoneurons projecting to the upper limb...
March 2, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/26903653/rehabilitation-drives-enhancement-of-neuronal-structure-in-functionally-relevant-neuronal-subsets
#9
Ling Wang, James M Conner, Alan H Nagahara, Mark H Tuszynski
We determined whether rehabilitation after cortical injury also drives dynamic dendritic and spine changes in functionally distinct subsets of neurons, resulting in functional recovery. Moreover, given known requirements for cholinergic systems in mediating complex forms of cortical plasticity, including skilled motor learning, we hypothesized that cholinergic systems are essential mediators of neuronal structural and functional plasticity associated with motor rehabilitation. Adult rats learned a skilled forelimb grasping task and then, underwent destructive lesions of the caudal forelimb region of the motor cortex, resulting in nearly complete loss of grasping ability...
March 8, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/26721868/paradoxical-motor-recovery-from-a-first-stroke-after-induction-of-a-second-stroke-reopening-a-postischemic-sensitive-period
#10
Steven R Zeiler, Robert Hubbard, Ellen M Gibson, Tony Zheng, Kwan Ng, Richard O'Brien, John W Krakauer
BACKGROUND AND OBJECTIVE: Prior studies have suggested that after stroke there is a time-limited period of increased responsiveness to training as a result of heightened plasticity-a sensitive period thought to be induced by ischemia itself. Using a mouse model, we have previously shown that most training-associated recovery after a caudal forelimb area (CFA) stroke occurs in the first week and is attributable to reorganization in a medial premotor area (AGm). The existence of a stroke-induced sensitive period leads to the counterintuitive prediction that a second stroke should reopen this window and promote full recovery from the first stroke...
September 2016: Neurorehabilitation and Neural Repair
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"