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https://www.readbyqxmd.com/read/29347782/stationary-uphill-currents-in-locally-perturbed-zero-range-processes
#1
Emilio N M Cirillo, Matteo Colangeli
Uphill currents are observed when mass diffuses in the direction of the density gradient. We study this phenomenon in stationary conditions in the framework of locally perturbed one-dimensional zero range processes (ZRPs). We show that the onset of currents flowing from the reservoir with smaller density to the one with larger density can be caused by a local asymmetry in the hopping rates on a single site at the center of the lattice. For fixed injection rates at the boundaries, we prove that a suitable tuning of the asymmetry in the bulk may induce uphill diffusion at arbitrarily large, finite volumes...
November 2017: Physical Review. E
https://www.readbyqxmd.com/read/29317020/thrombosis-of-the-hepatic-round-ligament-associated-with-acure-colangitis
#2
Andrea Craus Miguel, Fátima Sena Ruiz, Myriam Fernández Isart, Francisco González Argente
No abstract text is available yet for this article.
January 6, 2018: Cirugía Española
https://www.readbyqxmd.com/read/29311424/jaw-bones-regeneration-using-mesenchymal-stem-cells-a-single-center-experience
#3
Walter Colangeli, Umberto Riccelli, Amerigo Giudice, Ida Barca, Davide Caruso, Daniela Novembre, Claudio Tortosa, Raffaella Cordaro, Maria Giulia Cristofaro
PURPOSE: Mesenchymal stem cells (MSC), which are multipotent stromal cells, are considered to be a promising resource in tissue engineering and tissue regeneration. MSCs have been used to generate new maxillary bone with clinically successful results. The aim of this study was to determine the role of MSC in bone regeneration procedures in patients with benign maxillary lesions. METHODS: A study was conducted on five patients treated for maxillary bone defects resulting from biopsy of benign lesions at the University Hospital of Magna Græcia, Catanzaro, Italy from January 2015 to October 2016...
December 21, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29239563/a-geographical-information-system-for-the-management-of-the-aquaculture-data-in-the-adriatic-sea-the-strengthening-of-centres-for-aquaculture-production-and-safety-surveillance-in-the-adriatic-countries-experience-present-capabilities-tools-and-functions
#4
Susanna Tora, Silvio Sacchini, Eddy Listeš, Tanja Bogdanović, Alessio Di Lorenzo, Muhamed Smajlović, Ahmed Smajlović, Jelena V Filipović, Vildana Tahirović, Danijela Šuković, Bojan Beljkas, Ardian Xinxo, Renis Maçi, Patrizia Colangeli, Federica Di Giacinto, Annamaria Conte
The European Commission (EC) regulation no. 854/2004 requires a systematic monitoring of chemical and microbiological contaminants in live bivalve molluscs, live echinoderms, live tunicates and live marine gastropods for human consumption through surveillance plans to be implemented in all European Union (EU) countries.A consortium of five Adriatic countries was set up in the framework of the Instrument of Pre-accession Assistance Adriatic Cross-border Cooperation Programme (IPA Adriatic CBC) 2007- 2013 with the aim of collecting data and distribute information on harvesting and production in mollusc areas...
November 8, 2017: Geospatial Health
https://www.readbyqxmd.com/read/29210336/simplification-to-dual-therapy-containing-lamivudine-and-darunavir-ritonavir-or-atazanavir-ritonavir-in-hiv-infected-patients-on-virologically-suppressive-antiretroviral-therapy
#5
Leonardo Calza, Matteo Cafaggi, Vincenzo Colangeli, Marco Borderi, Enrico Barchi, Massimiliano Lanzafame, Stefano Nicole', Anna Maria Degli Antoni, Isabella Bon, Maria Carla Re, Pierluigi Viale
BACKGROUND: The ritonavir-boosted protease inhibitor (PI/r)-based dual regimens are warranted in order to optimize the combination antiretroviral therapy (cART), prevent the long-term toxicity and reduce the cost of treatments. METHODS: We performed an observational, retrospective study of HIV-infected patients on suppressive antiretroviral therapy who switched to a dual regimen containing lamivudine (3TC) plus darunavir/ritonavir (DRV/r) 800/100 mg qd or atazanavir/ritonavir (ATV/r) 300/100 mg qd...
December 6, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29161288/switch-to-maraviroc-with-darunavir-r-both-qd-in-patients-with-suppressed-hiv-1-was-well-tolerated-but-virologically-inferior-to-standard-antiretroviral-therapy-48-week-results-of-a-randomized-trial
#6
Barbara Rossetti, Roberta Gagliardini, Genny Meini, Gaetana Sterrantino, Vincenzo Colangeli, Maria Carla Re, Alessandra Latini, Manuela Colafigli, Francesca Vignale, Stefano Rusconi, Valeria Micheli, Antonio Di Biagio, Giancarlo Orofino, Valeria Ghisetti, Alessandra Fantauzzi, Vincenzo Vullo, Pierfrancesco Grima, Daniela Francisci, Claudio Mastroianni, Andrea Antinori, Michele Trezzi, Lucia Lisi, Pierluigi Navarra, Benedetta Canovari, Antonella D'Arminio Monforte, Silvia Lamonica, Alessandro D'Avino, Maurizio Zazzi, Simona Di Giambenedetto, Andrea De Luca
OBJECTIVES: Primary study outcome was absence of treatment failure (virological failure, VF, or treatment interruption) per protocol at week 48. METHODS: Patients on 3-drug ART with stable HIV-1 RNA <50 copies/mL and CCR5-tropic virus were randomized 1:1 to maraviroc with darunavir/ritonavir qd (study arm) or continue current ART (continuation arm). RESULTS: In June 2015, 115 patients were evaluable for the primary outcome (56 study, 59 continuation arm)...
2017: PloS One
https://www.readbyqxmd.com/read/29040768/overview-of-neutron-measurements-in-jet-fusion-device
#7
P Batistoni, R Villari, B Obryk, L W Packer, I E Stamatelatos, S Popovichev, A Colangeli, B Colling, N Fonnesu, S Loreti, A Klix, M Klosowski, K Malik, J Naish, M Pillon, T Vasilopoulou, P De Felice, M Pimpinella, L Quintieri
The design and operation of ITER experimental fusion reactor requires the development of neutron measurement techniques and numerical tools to derive the fusion power and the radiation field in the device and in the surrounding areas. Nuclear analyses provide essential input to the conceptual design, optimisation, engineering and safety case in ITER and power plant studies. The required radiation transport calculations are extremely challenging because of the large physical extent of the reactor plant, the complexity of the geometry, and the combination of deep penetration and streaming paths...
October 5, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28894217/the-faah-inhibitor-urb597-suppresses-hippocampal-maximal-dentate-afterdischarges-and-restores-seizure-induced-impairment-of-short-and-long-term-synaptic-plasticity
#8
Roberto Colangeli, Massimo Pierucci, Arcangelo Benigno, Giuseppe Campiani, Sefania Butini, Giuseppe Di Giovanni
Synthetic cannabinoids and phytocannabinoids have been shown to suppress seizures both in humans and experimental models of epilepsy. However, they generally have a detrimental effect on memory and memory-related processes. Here we compared the effect of the inhibition of the endocannabinoid (eCB) degradation versus synthetic CB agonist on limbic seizures induced by maximal dentate activation (MDA) acute kindling. Moreover, we investigated the dentate gyrus (DG) granule cell reactivity and synaptic plasticity in naïve and in MDA-kindled anaesthetised rats...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28731819/the-close-up-imager-onboard-the-esa-exomars-rover-objectives-description-operations-and-science-validation-activities
#9
Jean-Luc Josset, Frances Westall, Beda A Hofmann, John Spray, Charles Cockell, Stephan Kempe, Andrew D Griffiths, Maria Cristina De Sanctis, Luigi Colangeli, Detlef Koschny, Karl Föllmi, Eric Verrecchia, Larryn Diamond, Marie Josset, Emmanuelle J Javaux, Francesca Esposito, Matthew Gunn, Audrey L Souchon-Leitner, Tomaso R R Bontognali, Oleg Korablev, Suren Erkman, Gerhard Paar, Stephan Ulamec, Frédéric Foucher, Philippe Martin, Antoine Verhaeghe, Mitko Tanevski, Jorge L Vago
The Close-Up Imager (CLUPI) onboard the ESA ExoMars Rover is a powerful high-resolution color camera specifically designed for close-up observations. Its accommodation on the movable drill allows multiple positioning. The science objectives of the instrument are geological characterization of rocks in terms of texture, structure, and color and the search for potential morphological biosignatures. We present the CLUPI science objectives, performance, and technical description, followed by a description of the instrument's planned operations strategy during the mission on Mars...
June 2017: Astrobiology
https://www.readbyqxmd.com/read/28683645/substitution-of-nevirapine-or-raltegravir-for-protease-inhibitor-vs-rosuvastatin-treatment-for-the-management-of-dyslipidaemia-in-hiv-infected-patients-on-stable-antiretroviral-therapy-nevrast-study
#10
Leonardo Calza, Eleonora Magistrelli, Vincenzo Colangeli, Marco Borderi, Linda Bussini, Isabella Bon, Maria Carla Re, Pierluigi Viale
OBJECTIVES: An observational, prospective, cohort study was performed to compare efficacy and safety of a switch from ritonavir-boosted protease inhibitor (PI/r) to nevirapine or raltegravir with that of rosuvastatin addition to current antiretroviral therapy in HIV-infected patients with hyperlipidaemia. METHODS: All HIV-infected patients receiving a stable PI/r-based antiretroviral regimen, with persistently suppressed viremia, naïve to non-nucleoside analogues and to integrase strand transfer inhibitors, with mixed hyperlipidaemia, and who underwent a switch from PI/r to nevirapine (Group A) or raltegravir (Group B) or who started rosuvastatin at 10 mg daily (group C) with unchanged antiretroviral regimen were enrolled into the study...
July 6, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28647290/effect-of-professional-expertise-and-exposure-to-everyday-life-decision-making-on-moral-choices
#11
Maddalena Boccia, Paola Verde, Gregorio Angelino, Paolo Carrozzo, Diego Vecchi, Laura Piccardi, Stefano Colangeli, Pierluigi Cordellieri, Fabio Ferlazzo, Anna Maria Giannini
Moral sense is defined as a feeling of fairness or unfairness of an action that knowingly causes harm to people other than the subject. It is crucial in determining human behavior and becomes pivotal in operational environments. Here we assessed whether professional daily life experience in an operational environment affects moral judgment by asking 41 military pilots of the Italian Air Force (P) and 69 controls (C) to solve 40 moral dilemmas. We found that P gave more morally acceptable utilitarian responses to moral dilemmas...
June 21, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28632329/postictal-hypoperfusion-hypoxia-provides-the-foundation-for-a-unified-theory-of-seizure-induced-brain-abnormalities-and-behavioral-dysfunction
#12
REVIEW
Jordan S Farrell, Roberto Colangeli, Marshal D Wolff, Alexandra K Wall, Thomas J Phillips, Antis George, Paolo Federico, G Campbell Teskey
A recent article by Farrell et al. characterizes the phenomenon, mechanisms, and treatment of a local and severe hypoperfusion/hypoxia event that occurs in brain regions following a focal seizure. Given the well-established role of cerebral ischemia/hypoxia in brain damage and behavioral dysfunction in other clinical settings (e.g., stroke, cerebral vasospasm), we put forward a new theory: postictal hypoperfusion/hypoxia is responsible for the negative consequences associated with seizures. Fortunately, inhibition of two separate molecular targets, cyclooxygenase-2 (COX-2) and l-type calcium channels, can prevent the expression of postictal hypoperfusion/hypoxia...
September 2017: Epilepsia
https://www.readbyqxmd.com/read/28420298/prevalence-of-metabolic-syndrome-in-hiv-infected-patients-naive-to-antiretroviral-therapy-or-receiving-a-first-line-treatment
#13
Leonardo Calza, Vincenzo Colangeli, Eleonora Magistrelli, Nicolo' Rossi, Elena Rosselli Del Turco, Linda Bussini, Marco Borderi, Pierluigi Viale
BACKGROUND: The combination antiretroviral therapy (cART) has dramatically improved the life expectancy of patients with HIV infection, but may lead to several long-term metabolic abnormalities. However, data about the frequency of metabolic syndrome (MS) in HIV-infected people vary considerably across different observational studies. METHODS: The prevalence of MS among HIV-infected patients was evaluated by a cross-sectional study conducted among subjects naive to cART or receiving the first antiretroviral regimen and referring to our Clinics from January 2015 to December 2015...
May 2017: HIV Clinical Trials
https://www.readbyqxmd.com/read/28296514/can-unilateral-progressive-or-sudden-hearing-loss-be-immune-mediated-in-origin
#14
Francesca Atturo, Roberta Colangeli, Giorgio Bandiera, Maurizio Barbara, Simonetta Monini
OBJECTIVE: The aim of the present study was to demonstrate that the positivity of nonspecific immunological tests could be found not only in bilateral hearing loss but also in unilateral cases, either sudden or progressive. METHOD: An observational case series study included subjects suffering from unilateral or bilateral, sudden or progressive, symmetric or asymmetric sensorineural hearing loss (SNHL). All the patients underwent pure tone audiometry and the following battery of blood exams: anti-nuclear antibody (ANA), extractable nuclear antigen (ENA) antibody screening, anti-thyroperoxidase (anti-TPO), anti-thyroglobulin and anti-smooth muscle antibody (ASMA)...
March 15, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28116848/plasma-trough-concentrations-of-darunavir-ritonavir-and-raltegravir-in-older-patients-with-hiv-1-infection
#15
L Calza, V Colangeli, E Magistrelli, L Bussini, M Conti, E Ramazzotti, R Mancini, P Viale
OBJECTIVES: The aim of the study was to assess plasma concentrations of darunavir/ritonavir and raltegravir in older patients compared with younger patients with HIV-1 infection. METHODS: In this observational, open-label study, adult HIV-infected out-patients aged ≤ 40 years (younger patients) or ≥ 60 years (older patients) and treated with tenofovir/emtricitabine plus darunavir/ritonavir (800/100 mg daily) or raltegravir (400 mg twice daily) were asked to participate...
August 2017: HIV Medicine
https://www.readbyqxmd.com/read/28088884/dual-raltegravir-etravirine-combination-as-maintenance-regimen-in-virologically-suppressed-hiv-1-infected-patients
#16
Leonardo Calza, Eleonora Magistrelli, Vincenzo Colangeli, Roberto Manfredi, Marco Borderi, Nicolo' Rossi, Matteo Conti, Rita Mancini, Pierluigi Viale
BACKGROUND: Nucleoside reverse transcriptase inhibitor (NRTI)- and protease inhibitor (PI)-sparing antiretroviral regimens may be useful in selected human immune deficiency virus (HIV)-infected patients with resistance or intolerance to these drug classes. METHODS: This was an observational prospective study of patients on suppressive antiretroviral therapy containing two NRTIs plus one ritonavir-boosted PI who switched to a dual regimen containing raltegravir plus etravirine...
February 16, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28060020/significant-association-between-statin-associated-myalgia-and-vitamin-d-deficiency-among-treated-hiv-infected-patients
#17
Leonardo Calza, Eleonora Magistrelli, Vincenzo Colangeli, Marco Borderi, Ilaria Contadini, Isabella Bon, Maria Carla Re, Pierluigi Viale
BACKGROUND: Several studies have shown a significant association between vitamin D deficiency and an increased risk of statin-related symptomatic myalgia in the general population, but there are no data among HIV-infected persons. METHODS: A retrospective, cohort study was conducted to assess the incidence of symptomatic myalgia and elevation in serum creatine kinase level among HIV-positive adults on combination antiretroviral therapy and treated with atorvastatin or rosuvastatin for at least 12 months between 2011 and 2015 in our outpatient unit...
March 13, 2017: AIDS
https://www.readbyqxmd.com/read/27995558/is-there-benefit-to-free-over-pedicled-vascularized-grafts-in-augmenting-tibial-intercalary-allograft-constructs
#18
COMPARATIVE STUDY
Marco Manfrini, Srimanth Bindiganavile, Ferhat Say, Marco Colangeli, Laura Campanacci, Massimiliano Depaolis, Massimo Ceruso, Davide Donati
BACKGROUND: Intercalary reconstruction of tibial sarcomas with vascularized fibula autografts and massive bone allografts is reliable with predictable long-term results. However, inadequate data exist comparing free and pedicled vascularized fibula autografts in combination with a massive bone allograft in patients undergoing intercalary tibia reconstructions. QUESTIONS/PURPOSES: Among patients undergoing large-segment intercalary allografting, we sought to compare supplemental free vascularized fibular autografts with supplemental pedicled vascularized fibular autografts, in terms of (1) oncologic results, (2) complications associated with surgery, (3) Musculoskeletal Tumor Society (MSTS) scores, and (4) surgical time...
May 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27856846/seasonal-exposure-of-carbon-dioxide-ice-on-the-nucleus-of-comet-67p-churyumov-gerasimenko
#19
G Filacchione, A Raponi, F Capaccioni, M Ciarniello, F Tosi, M T Capria, M C De Sanctis, A Migliorini, G Piccioni, P Cerroni, M A Barucci, S Fornasier, B Schmitt, E Quirico, S Erard, D Bockelee-Morvan, C Leyrat, G Arnold, V Mennella, E Ammannito, G Bellucci, J Benkhoff, J P Bibring, A Blanco, M I Blecka, R Carlson, U Carsenty, L Colangeli, M Combes, M Combi, J Crovisier, P Drossart, T Encrenaz, C Federico, U Fink, S Fonti, M Fulchignoni, W-H Ip, P Irwin, R Jaumann, E Kuehrt, Y Langevin, G Magni, T McCord, L Moroz, S Mottola, E Palomba, U Schade, K Stephan, F Taylor, D Tiphene, G P Tozzi, P Beck, N Biver, L Bonal, J-Ph Combe, D Despan, E Flamini, M Formisano, A Frigeri, D Grassi, M S Gudipati, D Kappel, A Longobardo, F Mancarella, K Markus, F Merlin, R Orosei, G Rinaldi, M Cartacci, A Cicchetti, Y Hello, F Henry, S Jacquinod, J M Reess, R Noschese, R Politi, G Peter
Carbon dioxide (CO2) is one of the most abundant species in cometary nuclei, but because of its high volatility, CO2 ice is generally only found beneath the surface. We report the infrared spectroscopic identification of a CO2 ice-rich surface area located in the Anhur region of comet 67P/Churyumov-Gerasimenko. Spectral modeling shows that about 0.1% of the 80- by 60-meter area is CO2 ice. This exposed ice was observed a short time after the comet exited local winter; following the increased illumination, the CO2 ice completely disappeared over about 3 weeks...
December 23, 2016: Science
https://www.readbyqxmd.com/read/27727402/hiv-1-early-and-late-diagnosis-in-the-emilia-romagna-region-italy-a-three-year-study
#20
Giuseppina Musumeci, Giacomo Magnani, Isabella Bon, Serena Longo, Alessia Bertoldi, Anna Maria Degli Antoni, Maria Rita Rossi, Alessandro Ruggeri, Vittorio Sambri, Simona Semprini, Laura Sighinolfi, Maria Alessandra Ursitti, Alessandro Zerbini, Vincenzo Colangeli, Leonardo Calza, Alba Carola Finarelli, Erika Massimiliani, Maria Carla Re
It is crucial to establish the timing of infection and distinguish between early and long-lasting HIV-1 infections not only for partner notification and epidemiological surveillance, but also to offer early drug treatment and contain the spread of infection. This study analyzed serum and/or plasma samples with a first positive HIV antibody/antigen result coming from different Medical Centers in the Emilia Romagna Region, North East Italy, using the avidity assay, Western Blotting, RNA viral load, CD4 cell counts and genotyping assay...
October 2016: New Microbiologica
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