Anne Marshall, Leandros Rapteas, Jamie Burgess, David Riley, Matthew Anson, Kohei Matsumoto, Amanda Bennett, Stephen Kaye, Andrew Marshall, James Dunham, Nicholas Fallon, Sizheng S Zhao, Anne Pritchard, Nicola Goodson, Rayaz A Malik, Andreas Goebel, Bernhard Frank, Uazman Alam
A proportion of people with fibromyalgia demonstrate small fibre pathology (SFP). However, it is unclear how SFP directly relates to pain phenomenology. Thirty-three individuals with FMS and ten healthy volunteers underwent assessment of SFP and sensory phenotyping using corneal confocal microscopy, validated questionnaires and quantitative sensory testing (QST). Corneal nerve fibre length was used to stratify participants with fibromyalgia into with SFP [SFP+] and without SFP [SFP-]. SFP was detected in 50% of the fibromyalgia cohort...
February 16, 2024: Scientific Reports