keyword
MENU ▼
Read by QxMD icon Read
search

QST

keyword
https://www.readbyqxmd.com/read/29777310/mechanical-sensitivity-and-psychological-factors-in-patients-with-burning-mouth-syndrome
#1
Mika Honda, Takashi Iida, Hirona Kamiyama, Manabu Masuda, Misao Kawara, Peter Svensson, Osamu Komiyama
OBJECTIVES: The aim of this study was to compare mechanical sensitivity on the tongue using quantitative sensory testing (QST) and psychological factors using the General Health Questionnaire (GHQ) between burning mouth syndrome (BMS) patients and healthy participants. MATERIALS AND METHODS: Participants comprised 20 female BMS patients (68.1 ± 7.4 years) and 20 healthy females (65.4 ± 4.6 years). Psychological factors were evaluated with GHQ. Tactile detection thresholds (TDT) and filament-prick pain detection thresholds (FPT) were used to evaluate mechanical sensitivity on the tongue in all participants...
May 18, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29751194/the-central-sensitization-inventory-and-pain-sensitivity-questionnaire-an-exploration-of-construct-validity-and-associations-with-widespread-pain-sensitivity-among-individuals-with-shoulder-pain
#2
Rogelio A Coronado, Steven Z George
BACKGROUND: The Central Sensitization Inventory (CSI) and Pain Sensitivity Questionnaire (PSQ) are alternatives to quantitative sensory testing (QST) for inferring central sensitization. OBJECTIVE: Explore 1) comparative validity of the CSI and PSQ with QST (construct validity) and pain-related psychological questionnaires (concurrent validity), and 2) associations with widespread pain sensitivity. METHODS: Seventy-eight participants with unilateral shoulder pain less than 6 months (mean ± SD age = 39...
May 3, 2018: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/29742109/effect-of-single-dose-imipramine-on-chronic-low-back-and-experimental-pain-a-randomized-controlled-trial
#3
Jürg Schliessbach, Andreas Siegenthaler, Lukas Bütikofer, Andreas Limacher, Peter Juni, Pascal H Vuilleumier, Ulrike Stamer, Lars Arendt-Nielsen, Michele Curatolo
Antidepressants are frequently prescribed as co-analgesics in chronic pain. While their efficacy is well documented for neuropathic pain, the evidence is less clear in musculoskeletal pain conditions. The present study therefore evaluated the effect of the tricyclic antidepressant imipramine on chronic low-back pain in a randomized, double-blinded placebo-controlled design. To explore the mechanisms of action and the influence of drug metabolism, multimodal quantitative sensory tests (QST) and genotyping for cytochrome P450 2D6 (CYP2D6) were additionally performed...
2018: PloS One
https://www.readbyqxmd.com/read/29706009/relations-between-a-standardized-experimental-stressor-and-cutaneous-sensory-function-in-patients-with-chronic-pruritus-and-healthy-controls
#4
G Schneider, A Stumpf, M Burgmer, L Volmering, P Broecker, S Ständer
BACKGROUND: While chronic pruritus (CP) is a frequent symptom, many aspects of its underlying pathophysiological mechanisms still need elucidation. Research on sensory cutaneous function and on the influence of stress has been conducted mainly in patients with atopic dermatitis but is lacking for patients with CP. OBJECTIVE: To assess whether a standardized social stressor influences cutaneous sensory function in patients with CP in comparison to healthy controls (HC) METHODS: Case-control study; 33 CP and 30 HC were submitted to the standardized Quantitative Sensory Testing protocol before and after the Trier Social Stress Test and one hour later...
April 28, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29705914/a-longitudinal-study-of-painless-and-painful-intercostobrachial-neuropathy-after-breast-cancer-surgery
#5
S La Cesa, P Sammartino, C Mollica, G Cascialli, G Cruccu, A Truini, M Framarino-Dei-Malatesta
Intercostobrachial neuropathy, often resulting in neuropathic pain, is a common complication of breast cancer surgery. In this 1-year longitudinal study, we aimed at seeking information on the frequency, clinical features, and course of painless and painful intercostobrachial neuropathy. We enrolled 40 women previously undergoing breast cancer surgery. In these patients, we collected, at 3, 6 and 12 months after surgery, clinical and quantitative sensory testing (QST) variables to diagnose intercostobrachial neuropathy, DN4 questionnaire to identify neuropathic pain, Neuropathic Pain Symptom Inventory to assess the different neuropathic pain symptoms, the Beck Depression Inventory to assess depressive symptoms, and SF36 to assess quality of life and Patient Global Impression of Change...
April 29, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29681015/cold-therapy-to-prevent-paclitaxel-induced-peripheral-neuropathy
#6
Claire Griffiths, Nancy Kwon, Jennifer L Beaumont, Judith A Paice
PURPOSE: This case-control study was designed to assess the efficacy of cryotherapy to prevent paclitaxel-induced painful peripheral neuropathy in women with breast cancer. METHODS: Participants served as their own paired control, with randomization of the cooled glove/sock to either the dominant or the non-dominant hand/foot, worn for 15 min prior to, during, and 15 min after completion of the paclitaxel infusion. Outcome measures included the Neuropathic Pain Symptom Inventory, the Brief Pain Inventory, and quantitative sensory testing...
April 21, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29680433/night-shift-work-increases-cold-pain-perception
#7
Christoph Pieh, Robert Jank, Christoph Waiß, Christian Pfeifer, Thomas Probst, Claas Lahmann, Stefan Oberndorfer
BACKGROUND: Although night-shift work (NSW) is associated with a higher risk for several physical and mental disorders, the impact of NSW on pain perception is still unclear. This study investigates the impact of NSW on cold pain perception considering the impact of mood and sleepiness. METHOD: Quantitative sensory testing (QST) was performed in healthy night-shift workers. Cold pain threshold as well as tonic cold pain was assessed after one habitual night (T1), after a 12-hour NSW (T2) and after one recovery night (T3)...
May 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29663492/efficacy-of-epinephrine-free-articaine-compared-to-articaine-with-epinephrine-1-100-000-for-maxillary-infiltration-a-randomized-clinical-trial
#8
Konstantinos Paterakis, Marc Schmitter, Sareh Said Yekta-Michael
OBJECTIVE: The selection of local anesthetic in dental practice is essential to the patient's comfort and the success of the treatment. Many patients prefer anesthesia even for short treatments. Articaine is a local anesthetic commonly used for dental practice. The duration of the effect of articaine on the nerve fibers is not yet precisely reported. This study was aimed to evaluate the clinical efficacy of 4% articaine with and without epinephrine in treatment of occlusal caries. MATERIALS AND METHODS: Thirty healthy patients were included in this randomized double-blind study...
April 16, 2018: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29662721/neural-mechanisms-of-qigong-sensory-training-massage-for-children-with-autism-spectrum-disorder-a-feasibility-study
#9
Kristin K Jerger, Laura Lundegard, Aaron Piepmeier, Keturah Faurot, Amanda Ruffino, Margaret A Jerger, Aysenil Belger
Objectives: Despite the enormous prevalence of autism spectrum disorder (ASD), its global impact has yet to be realized. Millions of families worldwide need effective treatments to help them get through everyday challenges like eating, sleeping, digestion, and social interaction. Qigong Sensory Training (QST) is a nonverbal, parent-delivered intervention recently shown to be effective at reducing these everyday challenges in children with ASD. This study tested the feasibility of a protocol for investigating QST's neural mechanism...
2018: Global Advances in Health and Medicine: Improving Healthcare Outcomes Worldwide
https://www.readbyqxmd.com/read/29617461/adaptive-differentiation-of-festuca-rubra-along-a-climate-gradient-revealed-by-molecular-markers-and-quantitative-traits
#10
Bojana Stojanova, Mária Šurinová, Jaroslav Klápště, Veronika Koláříková, Věroslava Hadincová, Zuzana Münzbergová
Species response to climate change is influenced by predictable (selective) and unpredictable (random) evolutionary processes. To understand how climate change will affect present-day species, it is necessary to assess their adaptive potential and distinguish it from the effects of random processes. This will allow predicting how different genotypes will respond to forecasted environmental change. Space for time substitution experiments are an elegant way to test the response of present day populations to climate variation in real time...
2018: PloS One
https://www.readbyqxmd.com/read/29603439/deciphering-the-mechanism-of-human-carbonic-anhydrases-inhibition-with-sulfocoumarins-computational-and-experimental-studies
#11
Alessio Nocentini, Fabrizio Carta, Muhammet Tanc, Silvia Selleri, Claudiu T Supuran, Carla Bazzicalupi, Paola Gratteri
The reaction mechanism of the carbonic anhydrase-mediated hydrolysis of sulfocoumarins to sulfonic acids has been investigated on an enzyme cluster model using the B3LYP hybrid density functional theory (DFT) and the QST procedure for the Transition State (TS) search. A multistep process was highlighted, with the rate determining step identified in the initial dual nucleophilic/acidic attack of the zinc bound-hydroxide ion to the sulfocoumarin sulfur atom and to the C3-C4 double bond. The reported multi-step process, combined to SAR analysis on a new set of derivatives, highlighted unprecedentedly considered mechanistic aspects of the CA-mediated prodrug activation, which in turn do possess relevant consequences to the isoforms-selective inhibition profiles reported by such a class of compounds...
March 30, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29577496/transcranial-direct-current-stimulation-for-upper-limb-neuropathic-pain-a-double-blind-randomized-controlled-trial
#12
Gwyn N Lewis, David A Rice, Michal Kluger, Peter J McNair
BACKGROUND: While promising, there are mixed findings for the efficacy of transcranial direct current stimulation (tDCS) for the management of chronic pain. The goal of the current study was to evaluate the effect of anodal tDCS on pain and function in people with upper limb neuropathic pain. METHODS: The study was a double-blinded, randomized controlled trial. Thirty participants were randomly allocated into active and sham tDCS groups. Baseline assessments of pain and function, as well as quantitative sensory testing (QST) to probe the function of the nociceptive system, were undertaken prior to participants receiving five days of active or sham anodal tDCS (1 mA) over the primary motor cortex...
March 25, 2018: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29577469/natural-selection-and-neutral-evolutionary-processes-contribute-to-genetic-divergence-in-leaf-traits-across-a-precipitation-gradient-in-the-tropical-oak-quercus-oleoides
#13
Ramírez-Valiente A José, Nicholas J Deacon, Julie Etterson, Alyson Center, Jed P Sparks, Kimberlee L Sparks, Timothy Longwell, George Pilz, Jeannine Cavender-Bares
The impacts of drought are expanding worldwide as a consequence of climate change. However, there is still little knowledge of how species respond to long-term selection in seasonally-dry ecosystems. In this study, we used QST -FST comparisons to investigate (i) the role of natural selection on population genetic differentiation for a set of functional traits related to drought resistance in the seasonally-dry tropical oak Quercus oleoides and (ii) the influence of water availability at the site of population origin and in experimental treatments on patterns of trait divergence...
March 25, 2018: Molecular Ecology
https://www.readbyqxmd.com/read/29568686/transthyretin-familial-amyloid-polyneuropathy-ttr-fap-parameters-for-early-diagnosis
#14
Fabiola Escolano-Lozano, Ana Paula Barreiros, Frank Birklein, Christian Geber
Background: Familial transthyretin amyloidosis is a life-threatening disease presenting with sensorimotor and autonomic polyneuropathy. Delayed diagnosis has a detrimental effect on treatment and prognosis. To facilitate diagnosis, we analyzed data patterns of patients with transthyretin familial amyloid polyneuropathy (TTR-FAP) and compared them to polyneuropathies of different etiology for clinical and electrophysiological discriminators. Methods: Twenty-four patients with TTR-FAP and 48 patients with diabetic polyneuropathy (dPNP) were investigated (neurological impairment score NIS; neurological disability score NDS) in a cross-sectional design...
January 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29565955/chronic-pelvic-pain-neurogenic-or-non-neurogenic-warm-detection-threshold-testing-supports-a-diagnosis-of-pudendal-neuropathy
#15
Stanley J Antolak, Christopher M Antolak
BACKGROUND: Chronic pelvic pain (CPP) in men is rarely considered to have a neurogenic (neuropathic) basis. Separation of neurogenic from non-neurogenic pain is possible using clinical examination and neurophysiologic tests. A definite diagnosis of neuropathic pain can be made. OBJECTIVES: We aim to demonstrate that definite pudendal neuropathic abnormalities can be supported by a quantitative sensory test (QST) called the warm temperature threshold detection (WDT) test in men with CPP...
March 2018: Pain Physician
https://www.readbyqxmd.com/read/29554015/quantitative-sensory-testing-after-macroreplantation-evidence-for-a-specific-somatosensory-profile
#16
Kathrin R Blume, Juliane Racz, Marcel Franz, Caroline Dietrich, Christian Puta, Reinhard Friedel, Gunther O Hofmann, Wolfgang H R Miltner, Thomas Weiss
A comprehensive functional recovery is one of the criteria for successful replantation of an amputated limb. Functionality of a replanted limb is strongly dependent on its regained sensibility. In previous studies concerning the sensibility of replanted limbs, only a few somatosensory submodalities were examined in small samples. The purpose of the present study is to provide a full pattern of somatosensory symptoms following replantation. Quantitative Sensory Testing (QST) was carried out according to a standardized protocol in a sample of 15 patients who underwent replantation of their upper limb proximal to the radiocarpal joint (macroreplantation)...
March 15, 2018: Pain
https://www.readbyqxmd.com/read/29550702/surface-engineering-of-a-chromium-metal-organic-framework-with-bifunctional-ionic-liquids-for-selective-co-2-adsorption-synergistic-effect-between-multiple-active-sites
#17
Chong Chen, Nengjie Feng, Qirui Guo, Zhong Li, Xue Li, Jing Ding, Lei Wang, Hui Wan, Guofeng Guan
Targeting CO2 capture application, a new strategy for building multiple adsorption sites in metal-organic framework MIL-101(Cr) was constructed through the incorporation of diethylenetriamine-based ionic liquid (DETA-Ac) via a post-synthetic modification approach. The DETA-Ac, with multi-amine-tethered cation and acetate anion, could not only provide additional binding sites, but also enhance the affinity of framework surfaces toward CO2 . Simultaneously, the high surface area and large cage size of MIL-101(Cr) ensured the better dispersion of IL, thus exposing more active sites for CO2 adsorption...
March 12, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29541956/towards-bridging-translational-gap-in-cardiotoxicity-prediction-an-application-of-progressive-cardiac-risk-assessment-strategy-in-tdp-risk-assessment-of-moxifloxacin
#18
Nikunjkumar Patel, Oliver Hatley, Alexander Berg, Klaus Romero, Barbara Wisniowska, Debra Hanna, David Hermann, Sebastian Polak
Drug-induced cardiac arrhythmia, especially occurrence of torsade de pointes (TdP), has been a leading cause of attrition and post-approval re-labeling and withdrawal of many drugs. TdP is a multifactorial event, reflecting more than just drug-induced cardiac ion channel inhibition and QT interval prolongation. This presents a translational gap in extrapolating pre-clinical and clinical cardiac safety assessment to estimate TdP risk reliably, especially when the drug of interest is used in combination with other QT-prolonging drugs for treatment of diseases such as tuberculosis...
March 14, 2018: AAPS Journal
https://www.readbyqxmd.com/read/29541548/asymptomatic-loss-of-intraepidermal-nerve-fibers-with-preserved-thermal-detection-thresholds-after-repeated-exposure-to-severe-cold
#19
Thomas Krøigård, Martin Wirenfeldt, Toke K Svendsen, Søren H Sindrup
Background: Cold-induced peripheral neuropathy has been described in individuals exposed to severe cold resulting in pain, hypersensitivity to cold, hyperhidrosis, numbness, and skin changes. Nerve conduction studies and thermal detection thresholds are abnormal in symptomatic patients, and intraepidermal nerve fiber density (IENFD) in skin biopsies is reduced. Case presentation: A 41-year-old male was included as a healthy subject in a study of the spontaneous variability of quantitative sensory testing (QST), nerve conduction studies (NCS), and IENFD...
March 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29526115/sensory-profiles-are-comparable-in-patients-with-distal-and-proximal-entrapment-neuropathies-while-the-pain-experience-differs
#20
Brigitte Tampin, Jan Vollert, Annina B Schmid
OBJECTIVE: Distal and proximal entrapment neuropathies such as carpal tunnel syndrome (CTS) and cervical radiculopathy (CR) share similar etiologies. Experimental models suggest that, despite comparable etiology, pathomechanisms associated with injuries of the peripheral and central axon branches are distinct. This study therefore compared self-reported and elicited sensory profiles in patients with distal and proximal entrapment neuropathies. METHODS: Patients with electrodiagnostically confirmed CTS (n = 103) and patients with CR (n = 23) were included in this study...
April 13, 2018: Current Medical Research and Opinion
keyword
keyword
86843
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"