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https://www.readbyqxmd.com/read/29126222/lumbar-disc-herniation-the-association-between-quantitative-sensorial-test-and-magnetic-resonance-imaging-findings
#1
Serpil Canan Erbüyün, Gülgün Yilmaz Ovali, Beyhan Özyurt, E Alp Yentür
Objective: Quantitative sensorial tests (QST) are used for evaluating specific sensorial nerve function. In this study, QST and magnetic resonance imaging (MRI) findings are compared in lumbar disc herniation patients, and the accuracy of QST data was investigated. Material and Methods: Sixty-four patients between 18 and 70 years of age suffering from radicular pain with positive Lasegue's test were included in this study. Specific criteria included complaints due to L5 discopathy...
November 6, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29105897/chronic-intensive-care-related-pain-exploratory-analysis-on-predictors-and-influence-on-health-related-quality-of-life
#2
P Baumbach, T Götz, A Günther, T Weiss, W Meissner
BACKGROUND: There is growing evidence for the development of chronic pain after intensive care. Nonetheless, there is only limited knowledge about factors leading to chronic intensive care-related pain (CIRP). Thus, the primary objective was the identification of predictors of CIRP. Moreover, we aimed to assess the impact of CIRP on patients' health-related quality of Life (HRQOL). METHODS: Comprehensive information on patients' pain before ICU admission and present pain was collected longitudinally by means of the German Pain Questionnaire 6 and 12 months after ICU discharge (ICUDC )...
November 5, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29089923/sensory-alterations-in-patients-with-isolated-idiopathic-dystonia-an-exploratory-quantitative-sensory-testing-analysis
#3
Lejla Paracka, Florian Wegner, Christian Blahak, Mahmoud Abdallat, Assel Saryyeva, Dirk Dressler, Matthias Karst, Joachim K Krauss
Abnormalities in the somatosensory system are increasingly being recognized in patients with dystonia. The aim of this study was to investigate whether sensory abnormalities are confined to the dystonic body segments or whether there is a wider involvement in patients with idiopathic dystonia. For this purpose, we recruited 20 patients, 8 had generalized, 5 had segmental dystonia with upper extremity involvement, and 7 had cervical dystonia. In total, there were 13 patients with upper extremity involvement...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29069724/association-of-serum-ninjurin2-levels-with-neurologic-damage-and-postherpetic-neuralgia-occurrence-an-observational-cohort-study-in-chinese-herpeszoster-patients
#4
Guozhuan Zhang, Yingjiao Sun, Lei Wang, Hui Tian, Lishuang Liang
OBJECTIVES: Postherpetic neuralgia(PHN) is the most common complication of herpeszoster (HZ) infection. The study aimed to explore whether serum Ninjurin2 (for nerve injury-induced protein 2, NINJ2), a novel neurologic damage related protein, is associated with nerve injury and the occurrence of PHN. RESULTS: Seventy-four of the eighty patients completed the study. On the 7th day of AHN, the patients had significantly higher values of NINJ2, cold-sense dispersion (ΔCS), warm-sense dispersion (ΔWS), cold-pain dispersion (ΔCP), heat-pain dispersion (ΔHP) and NRS score compared to controls...
September 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/29067398/investigating-gas-sorption-in-an-rht-metal-organic-framework-with-1-2-3-triazole-groups
#5
Katherine A Forrest, Tony Pham, Brian Space
Simulations of CO2 and H2 sorption were performed in an rht-metal-organic framework (MOF) that consists of Cu(2+) ions coordinated to 5,5',5''-(4,4',4''-(benzene-1,3,5-triyl)tris(1H-1,2,3-triazole-4,1-diyl))triisophthalate (BTTI) linkers; it is referred to as Cu-BTTI herein. This MOF was previously synthesized and reported by three different experimental groups [Zhao et al., Sci. Rep., 2013, 3, 1149; Schröder et al., Chem. Sci., 2013, 4, 1731-1736; Hupp et al., Energy Environ. Sci., 2013, 6, 1158-1163]. This MOF is notable for the presence of open-metal sites and nitrogen-rich regions through the copper paddlewheel ([Cu2(O2CR)4]) clusters and 1,2,3-triazole groups, respectively, which allows this material to display remarkable CO2 and H2 sorption properties...
November 8, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29032189/laser-evoked-potentials-in-painful-radiculopathy
#6
P Hüllemann, C von der Brelie, G Manthey, J Düsterhöft, A K Helmers, M Synowitz, J Gierthmühlen, R Baron
OBJECTIVE: The aims of this exploratory study were (1) to develop a standardized objective electrophysiological technique with laser-evoked potentials to assess dorsal root damage quantitatively and (2) to correlate these LEP measures with clinical parameters and sensory abnormalities (QST) in the affected dermatome. METHODS: Thirty-eight patients with painful radiculopathy and 20 healthy subjects were investigated with LEP recorded from the affected dermatome and control areas as well as with quantitative sensory testing...
September 28, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29025096/efficacy-of-vibrating-gloves-for-chronic-hand-pain-due-to-osteoarthritis
#7
Robert N Jamison, Anna Mei, Robert R Edwards, Edgar L Ross
Objective: This study investigated the efficacy of vibration technology for women with hand pain due to osteoarthritis (OA) to see if mild compression and small vibrating motors were beneficial with periodic use. Methods: Sixty-nine (N = 69) women with OA hand pain were randomized into two groups, one that used vibrating gloves once a day for 20 minutes (Experimental, N = 34) and one that was monitored for three months without gloves (Control, N = 35)...
September 14, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28980347/sensory-processing-and-central-pain-modulation-in-patients-with-chronic-shoulder-pain-a-case-control-study
#8
K Kuppens, G Hans, N Roussel, F Struyf, E Fransen, P Cras, C P Van Wilgen, J Nijs
Chronicity and recurrence in musculoskeletal shoulder pain are highly prevalent and can possibly be attributed to the concept of central sensitization. Available studies suggest a role for central sensitization in explaining chronic shoulder pain, but so far a comprehensive quantitative sensory testing (QST) protocol has not been used. The aim of this study was to gain knowledge on sensory processing and central pain modulatory mechanisms in patients suffering from chronic shoulder pain using such a QST protocol...
October 4, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28974374/the-role-of-sex-in-sleep-deprivation-related-changes-of-nociception-and-conditioned-pain-modulation
#9
Nicole Eichhorn, Rolf-Detlef Treede, Sigrid Schuh-Hofer
Sex matters both in the clinical field of pain and sleep medicine. Sleep disturbances are highly prevalent in chronic pain patients and have been shown to deteriorate the pain condition. The pathomechanisms by which insomnia aggravates pain are currently unknown. Descending pain control may be compromised by disturbed sleep, but respective studies are few, inconsistent and largely imbalanced with respect to sex. We studied the role of sex on the effect of sleep deprivation on endogenous pain modulation and on nociceptive thresholds in a highly homogenous study population of 18 female (23...
October 1, 2017: Neuroscience
https://www.readbyqxmd.com/read/28967356/pain-sensitisation-in-osteoarthritis
#10
REVIEW
Lars Arendt-Nielsen
Treating chronic musculoskeletal pain, and chronic joint pain (osteoarthritis (OA)) in particular, is challenging as the peripheral and central pain mechanisms are not fully discovered, and safe and as efficient analgesic drugs are not available. In general, the preclinical models of OA are limited to provide fundamental understanding of the pain mechanisms involved in patients with chronic joint pain (1). The pain associated with joint discomfort is highly variable, often underestimated by clinicians, and shows only modest association with crude radiological scorings...
September 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28958193/quantitative-sensory-testing-qst-in-the-orofacial-region-of-healthy-chinese-influence-of-site-gender-and-age
#11
Yanting Wang, Xueyin Mo, Jinglu Zhang, Yuan Fan, Kelun Wang, Svensson Peter
OBJECTIVE: To establish a preliminary thermal and mechanical somatosensory profile using a standardized quantitative sensory testing (QST) to investigate site, gender and age differences in healthy Chinese. MATERIALS AND METHODS: Twenty younger (age: 20-40 years, 10 men, 10 women) and twenty older (age: 41-61 years, 10 men, 10 women) healthy participants completed the study. Cold detection threshold (CDT), warm detection threshold (WDT), cold pain threshold (CPT), heat pain threshold (HPT), mechanical detection threshold (MDT) and mechanical pain threshold (MPT) were measured at five sites: Left hand, bilaterally at the mental area, tip of tongue and the lower lip mucosa...
September 28, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28956436/effective-approach-for-increasing-the-heteroatom-doping-levels-of-porous-carbons-for-superior-co2-capture-and-separation-performance
#12
Yomna H Abdelmoaty, Tsemre-Dingel Tessema, Nazgol Norouzi, Oussama M El-Kadri, Joseph B McGee Turner, Hani M El-Kaderi
Development of efficient sorbents for carbon dioxide (CO2) capture from flue gas or its removal from natural gas and landfill gas is very important for environmental protection. A new series of heteroatom-doped porous carbon was synthesized directly from pyrazole/KOH by thermolysis. The resulting pyrazole-derived carbons (PYDCs) are highly doped with nitrogen (14.9-15.5 wt %) as a result of the high nitrogen-to-carbon ratio in pyrazole (43 wt %) and also have a high oxygen content (16.4-18.4 wt %). PYDCs have a high surface area (SABET = 1266-2013 m(2) g(-1)), high CO2 Qst (33...
October 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28937248/theta-burst-stimulation-in-the-treatment-of-chronic-orofacial-pain-a-randomized-controlled-trial
#13
B Kohútová, J Fricová, M Klírová, T Novák, R Rokyta
Theta burst stimulation (TBS) is a modified form of high-frequency repetitive transcranial magnetic stimulation (rTMS) with promising effect in chronic pain. The aim of our double-blind, sham-controlled, parallel-group, randomized study was to assess an efficacy of intermittent TBS (iTBS) in the treatment of patients with chronic orofacial pain. Nineteen patients (twelve females) with chronic orofacial pain were prospectively included and randomly assigned to single session of an active (iTBS) or sham (intermediate TBS; imTBS) stimulation delivered to the primary motor cortex (M1) contralateral to painful side...
September 22, 2017: Physiological Research
https://www.readbyqxmd.com/read/28929829/quantitative-sensory-testing-for-assessment-of-somatosensory-function-in-human-oral-mucosa-a-review
#14
Pin Zhou, Yaming Chen, Jinglu Zhang, Kelun Wang, Peter Svensson
OBJECTIVE: This narrative review provides an overview of the quantitative sensory testing (QST) to assess somatosensory function in human oral mucosa. MATERIAL AND METHODS: A literature search was conducted in the PubMed database to identify studies in vivo on human oral mucosa using QST methods. A list of 149 articles was obtained and screened. A total of 36 relevant articles remained and were read in full text. Manual search of the reference lists identified eight additional relevant studies...
September 20, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28925520/rational-design-of-a-bifunctional-two-fold-interpenetrated-zn-ii-metal-organic-framework-for-selective-adsorption-of-co2-and-efficient-aqueous-phase-sensing-of-2-4-6-trinitrophenol
#15
Sandeep Singh Dhankhar, Nayuesh Sharma, Sandeep Kumar, T J Dhilip Kumar, C M Nagaraja
A bifunctional, microporous Zn(II) metal-organic framework, [Zn2 (NH2 BDC)2 (dpNDI)]n (MOF1) (where, NH2 BDC=2-aminoterephthalic acid, dpNDI=N,N'-di(4-pyridyl)-1,4,5,8-naphthalenediimide) has been synthesized solvothermally. MOF1 shows an interesting two-fold interpenetrated, 3D pillar-layered framework structure composed of two types of 1D channels with dimensions of approximately 2.99×3.58 Å and 4.58×5.38 Å decorated with pendent -NH2 groups. Owing to the presence of a basic functionalized pore surface, MOF1 exhibits selective adsorption of CO2 with high value of heat of adsorption (Qst =46...
September 19, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28919806/how-stable-are-quantitative-sensory-testing-measurements-over-time-report-on-10-week-reliability-and-agreement-of-results-in-healthy-volunteers
#16
Helen Nothnagel, Christian Puta, Thomas Lehmann, Philipp Baumbach, Martha B Menard, Brunhild Gabriel, Holger H W Gabriel, Thomas Weiss, Frauke Musial
BACKGROUND: Quantitative sensory testing (QST) is a diagnostic tool for the assessment of the somatosensory system. To establish QST as an outcome measure for clinical trials, the question of how similar the measurements are over time is crucial. Therefore, long-term reliability and limits of agreement of the standardized QST protocol of the German Research Network on Neuropathic Pain were tested. METHODS: QST on the lower back and hand dorsum (dominant hand) were assessed twice in 22 healthy volunteers (10 males and 12 females; mean age: 46...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28894389/quantification-of-small-fiber-pathology-in-patients-with-sarcoidosis-and-chronic-pain-using-cornea-confocal-microscopy-and-skin-biopsies
#17
Linda Cj Oudejans, Marieke Niesters, Michael Brines, Albert Dahan, Monique van Velzen
Small fiber pathology with concomitant chronic neuropathic pain is a common complication of sarcoidosis. The gold standard of diagnosis of small fiber neuropathy (SFN) is the quantification of small nerve fibers in skin biopsies in combination with patient history and psychophysical tests; a new technique is the quantification of small nerve fibers in the cornea using cornea confocal microscopy (CCM). Here, we studied small fiber morphology in sarcoidosis patients with neuropathic pain using skin biopsies, CCM, and quantitative sensory testing (QST)...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28879245/effects-of-high-dose-capsaicin-on-tmd-subjects-a-randomized-clinical-study
#18
B K Campbell, R B Fillingim, S Lee, R Brao, D D Price, J K Neubert
Temporomandibular joint disorder (TMD) is a complex musculoskeletal disorder that presents with pain, limited jaw opening, and abnormal noises in the temporomandibular joint. Despite the significant impact that TMD has in terms of suffering and financial burden, relatively few new treatments have emerged; therefore, development of novel treatments to treat TMD pain remains a high priority. The rationale of this study was to use a double-blind, vehicle-controlled clinical trial to evaluate the effects of a high-concentration (8%) capsaicin cream on TMD...
January 2017: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/28865379/quantitative-sensory-tests-qst-are-promising-tests-for-clinical-relevance-of-anti-nociceptive-effects-of-new-analgesic-treatments
#19
Satu K Jääskeläinen
No abstract text is available yet for this article.
August 30, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28859684/sex-differences-in-thermal-detection-and-thermal-pain-threshold-and-the-thermal-grill-illusion-a-psychophysical-study-in-young-volunteers
#20
Beate Averbeck, Lena Seitz, Florian P Kolb, Dieter F Kutz
BACKGROUND: Sex-related differences in human thermal and pain sensitivity are the subject of controversial discussion. The goal of this study in a large number of subjects was to investigate sex differences in thermal and thermal pain perception and the thermal grill illusion (TGI) as a phenomenon reflecting crosstalk between the thermoreceptive and nociceptive systems. The thermal grill illusion is a sensation of strong, but not necessarily painful, heat often preceded by transient cold upon skin contact with spatially interlaced innocuous warm and cool stimuli...
September 1, 2017: Biology of Sex Differences
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