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https://www.readbyqxmd.com/read/29684602/trans-cinnamic-acid-application-for-rainbow-trout-oncorhynchus-mykiss-i-effects-on-haematological-serum-biochemical-non-specific-immune-and-head-kidney-gene-expression-responses
#1
Sevdan Yilmaz, Sebahattin Ergün
The present study investigated the effects of dietary trans-cinnamic acid (CA) on pre- and post-challenge haematological, serum biochemical, non-specific immune and head kidney gene expression responses of rainbow trout, Oncorhynchus mykiss juveniles. In this regard, fish with an average weight of 17.01 ± 0.05 g were divided into five groups, and fed daily with an additive free basal diet (control); 250, 500, 750 or 1500 mg kg-1  CA for a 60-day period. Fish were sampled every 20 days during the experiment...
April 20, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29684131/the-somatic-marker-hypothesis-and-sexual-decision-making-understanding-the-role-of-iowa-gambling-task-performance-and-daily-sexual-arousal-on-the-sexual-behavior-of-gay-and-bisexual-men
#2
H Jonathon Rendina, Brett M Millar, Genevieve Dash, Sarah W Feldstein Ewing, Jeffrey T Parsons
Background: The sexual decision-making literature suggests that sexual arousal and behavior are associated. The somatic marker hypothesis suggests that individual neuropsychological differences in decision making, as measured by the Iowa Gambling Task (IGT), may moderate these associations; however, this hypothesis has yet to be tested with event-level sexual behavior data. Purpose: We hypothesized that (a) daily sexual arousal would be positively associated with likelihood of engaging in sex and condomless anal sex (CAS) and (b) IGT scores would moderate these associations such that the associations would be stronger among those with higher IGT scores...
April 19, 2018: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/29683455/three-dimensional-inflammatory-human-tissue-equivalents-of-gingiva
#3
Li Xiao, Hisashi Okamura, Yasuo Kumazawa
Periodontal diseases (such as gingivitis and periodontitis) are the leading causes of tooth loss in adults. Inflammation in gingiva is the fundamental physiopathology of periodontal diseases. Current experimental models of periodontal diseases have been established in various types of animals. However, the physiopathology of animal models is different from that of humans, making it difficult to analyze cellular and molecular mechanisms and evaluate new medicines for periodontal diseases. Here, we present a detailed protocol for reconstructing human inflammatory tissue equivalents of gingiva (iGTE) in vitro...
April 3, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29680359/effects-of-6-vs-3-eucaloric-meal-patterns-on-glycaemic-control-and-satiety-in-people-with-impaired-glucose-tolerance-or-overt-type-2-diabetes-a-randomized-trial
#4
E Papakonstantinou, M D Kontogianni, P Mitrou, E Magriplis, D Vassiliadi, T Nomikos, V Lambadiari, E Georgousopoulou, G Dimitriadis
BACKGROUND/OBJECTIVES: The study aimed to compare the effects of two eucaloric meal patterns (3 vs 6 meals/day) on glycaemic control and satiety in subjects with impaired glucose tolerance and plasma glucose (PG) levels 140-199mg/dL at 120min (IGT-A) or PG levels 140-199mg/dL at 120min and >200mg/dL at 30/60/90min post-oral glucose load on 75-g OGTT (IGT-B), or overt treatment-naïve type 2 diabetes (T2D). SUBJECTS/METHODS: In this randomized crossover study, subjects with IGT-A (n=15, BMI: 32...
April 6, 2018: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29679628/long-and-short-term-outcomes-of-gestational-diabetes-mellitus-gdm-among-south-asian-women-a-community-based-study
#5
REVIEW
B H Sudasinghe, C N Wijeyaratne, P S Ginige
AIMS: To quantify short and long-term outcomes of Gestational Diabetes Mellitus (GDM) among South Asians METHODS: Prospective cohort-study in Gampaha District, Sri Lanka following a community-prevalence study (WHO 1999 criteria). All women with GDM (exposed) and within sample non-GDM (non-exposed) were recruited. Data was gathered at selected intervals until one-year post-partum by interviewer-administered questionnaire, anthropometry, blood pressure, post-partum 75gOGTT and cholesterol...
April 18, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29673500/the-time-bomb-of-igt
#6
EDITORIAL
Suvi Karuranga, Anne Wiebke Ohlrogge
No abstract text is available yet for this article.
April 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29672742/older-subjects-with-%C3%AE-cell-dysfunction-have-an-accentuated-incretin-release
#7
José de Jesús Garduno-Garcia, Amalia Gastaldelli, Ralph A DeFronzo, Raweewan Lertwattanarak, Jens J Holst, Nicolas Musi
Objective: Insulin secretion declines with age and this contributes to the increased risk of developing impaired glucose tolerance (IGT) and type 2 diabetes mellitus (T2DM) in older subjects. Insulin secretion is regulated by the incretin hormones glucagon-like peptide (GLP) 1 and glucose-dependent insulinotropic peptide (GIP). Here we tested the hypotheses that incretin release is reduced in older subjects, and that this decline is associated with β-cell dysfunction. Research Design: 40 young (25±3 y) and 53 older (74±7 y) lean non-diabetic subjects underwent a 2 h oral glucose tolerance test (OGTT)...
April 16, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29667317/relationships-between-executive-function-working-memory-and-decision-making-on-the-iowa-gambling-task-evidence-from-ventromedial-patients-dorsolateral-patients-and-normal-subjects
#8
Riadh Ouerchefani, Naoufel Ouerchefani, Philippe Allain, Mohamed Riadh Ben Rejeb, Didier Le Gall
The results of previous studies are inconsistent in regard to the relationship between the Iowa Gambling Task (IGT), working-memory (WM), and executive tasks, and whether these cognitive processes could be considered as mechanisms underlying a decision-making deficit. Moreover, the relationship between the IGT and executive measures is examined based on a limited number of executive tasks, within different populations showing diffuse damage. In addition, there are fewer studies carried out within control participants, with those studies also being inconclusive...
April 17, 2018: Journal of Neuropsychology
https://www.readbyqxmd.com/read/29665516/-cool-and-hot-executive-functions-in-suicide-attempters-with-major-depressive-disorder
#9
Ming-Chou Ho, Yi-Chieh Hsu, Mong-Liang Lu, Michael Gossop, Vincent Chin-Hung Chen
RATIONALE: The World Health Organization reports that, by 2030, depression is expected to be the largest contributor to disease burden. Only small proportion of patients with major depressive disorder (MDD) achieves remission and the majority of them do not achieve long-term functional recovery. One of the neuropsychological domains that have been shown to be particularly impaired in depression, is that of executive function (EF). OBJECTIVES: We examined whether the patients with MDD with and without suicide attempts had deteriorated 'cool' EF and 'hot' EF...
April 7, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29643267/measurement-of-breath-acetone-in-patients-referred-for-an-oral-glucose-tolerance-test
#10
Brian Terence Andrews, Wolfgang Denzer, Gus Hancock, Dan Lunn, Robert Peverall, Grant Ritchie, Karen Williams
Breath acetone concentrations were measured in 141 subjects (aged 19-91 yrs, mean=59.11yrs standard deviation=12.99yrs), male and female, undergoing an oral glucose tolerance test (OGTT), having been referred to clinic on suspicion of type 2 diabetes. Breath samples were measured using an ion-molecule-reaction mass spectrometer, at the commencement of the OGTT, and after 1 and 2hrs. Subjects were asked to observe the normal routine before and during the OGTT, which includes an overnight fast and ingestion of 75g glucose at the beginning of the routine...
April 12, 2018: Journal of Breath Research
https://www.readbyqxmd.com/read/29624902/one-hour-ogtt-plasma-glucose-at-gdm-diagnosis-is-a-common-predictor-of-the-need-for-insulin-therapy-in-pregnancy-and-postpartum-impaired-glucose-tolerance
#11
Takeshi Nishikawa, Keiko Ono, Shoko Hashimoto, Hiroyuki Kinoshita, Takuro Watanabe, Hirotaka Araki, Kae Otsu, Wakana Sakamoto, Masahiro Harada, Tetsushi Toyonaga, Shoichi Kawakami, Jyunichiro Fukuda, Yoshio Haga, Daisuke Kukidome, Takeshi Takahashi, Eiich Araki
AIMS/INTRODUCTION: Because gestational diabetes mellitus (GDM) is a risk for adverse perinatal outcomes, and patients with a history of GDM have an increased risk of impaired glucose tolerance (IGT). Here, we conducted two non-interventional and retrospective studies of GDM patients in Japan. MATERIALS AND METHODS: In the first study, we enrolled 529 GDM patients and assessed predictors of the need for insulin therapy. In the second study, we enrolled 185 patients from the first study, and assessed predictors of postpartum IGT...
April 6, 2018: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/29624416/traditional-chinese-patent-medicine-for-treating-impaired-glucose-tolerance-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#12
Bing Pang, Qing Ni, Yi-Qun Lin, Yi-Tian Wang, Yu-Jiao Zheng, Xue-Min Zhao, Shuo Feng, Xiao-Lin Tong
INTRODUCTION/AIM: To assess the effectiveness and safety of Traditional Chinese patent medicines (TCPMs) for managing impaired glucose tolerance (IGT). METHODS: Seven databases were searched to identify eligible trials published from incepting to May 1, 2016. Randomized controlled trials (RCTs) involving TCPM for IGT with a minimum follow-up duration of 6 months were included for analysis. Data extraction and quality assessment were performed by two reviewers independently...
April 6, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29615972/prediction-of-glucose-tolerance-without-an-oral-glucose-tolerance-test
#13
Rohit Babbar, Martin Heni, Andreas Peter, Martin Hrabě de Angelis, Hans-Ulrich Häring, Andreas Fritsche, Hubert Preissl, Bernhard Schölkopf, Róbert Wagner
Introduction: Impaired glucose tolerance (IGT) is diagnosed by a standardized oral glucose tolerance test (OGTT). However, the OGTT is laborious, and when not performed, glucose tolerance cannot be determined from fasting samples retrospectively. We tested if glucose tolerance status is reasonably predictable from a combination of demographic, anthropometric, and laboratory data assessed at one time point in a fasting state. Methods: Given a set of 22 variables selected upon clinical feasibility such as sex, age, height, weight, waist circumference, blood pressure, fasting glucose, HbA1c, hemoglobin, mean corpuscular volume, serum potassium, fasting levels of insulin, C-peptide, triglyceride, non-esterified fatty acids (NEFA), proinsulin, prolactin, cholesterol, low-density lipoprotein, HDL, uric acid, liver transaminases, and ferritin, we used supervised machine learning to estimate glucose tolerance status in 2,337 participants of the TUEF study who were recruited before 2012...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29615002/triglycerides-and-total-cholesterol-concentrations-in-association-with-ifg-igt-in-chinese-adults-in-qingdao-china
#14
Jing Cui, Jianping Sun, Wei Wang, Nafeesa Yasmeen, Ma Ke, Hualei Xin, Qing Qiao, Aiguo Ma, Zulqarnain Baloch
BACKGROUND: To investigative the association of triglycerides (TG) and total cholesterol (TC) concentrations with impaired fasting glucose/ impaired glucose tolerance (IFG/IGT) in Chinese adults. METHODS: The population-based cross-sectional diabetes survey was conducted in 2006 and 2009 in Qingdao, separately. 4400 participants (1 793 men and 2607 women) were include in current analysis. IFG/IGT was defined according to fasting plasma glucose (FPG) and/or 2 h post-load plasma glucose (2 h PG)...
April 3, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29614700/personality-traits-and-cortical-activity-affect-gambling-behavior-in-parkinson-s-disease
#15
Michela Balconi, Chiara Siri, Nicoletta Meucci, Gianni Pezzoli, Laura Angioletti
BACKGROUND: Pathological gambling (PG) in Parkinson's disease (PD) manifests as a persistent and uncontrollable gambling behavior, characterized by dysfunctional decision-making and emotional impairment related to high-risk decisions. OBJECTIVE: The aim of this study was to explore the relationship between personality traits and prefrontal cortex activity in PD patients with or without PG. METHODS: Thus, hemodynamic cortical activity measured by functional near-infrared spectroscopy (fNIRS) and Iowa Gambling Task (IGT) performance were recorded in forty-six PD patients, divided into three groups according to their gambling status: PD patients with active gambling behavior (PDG); PD patients who remitted from PG (PDNG); and a control group (CG) composed by patients with PD only...
March 26, 2018: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/29603379/impact-of-prediabetes-on-poststroke-depression-in-chinese-patients-with-acute-ischemic-stroke
#16
REVIEW
Meijuan Xiao, Qiongzhang Wang, Wenwei Ren, Zheng Zhang, Xujie Wu, Zhen Wang, Liang Feng, Siyan Chen, Jincai He
OBJECTIVE: It is unknown whether prediabetes is a predictor of poststroke depression (PSD). We aimed to explore the relationship between prediabetes and PSD in Chinese patients with acute ischemic stroke. METHODS: This is a prospective cohort study, and a total of 358 patients with acute ischemic stroke were recruited and enrolled. Patients were divided into 3 groups: normal glucose group (NGT, n = 96), prediabetes group (preDM, n = 134, impaired fasting glucose (IFG), and/or impaired glucose tolerance (IGT) and/or HbA1c (A1c) 5...
March 30, 2018: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29596944/postpartum-risk-of-diabetes-and-predictive-factors-for-glucose-intolerance-in-east-asian-women-with-gestational-diabetes
#17
Hiromi Inoue, Ko Ishikawa, Kenji Takeda, Akina Kobayashi, Kenichi Kurita, Jin Kumagai, HidetakaYokoh, Koutaro Yokote
AIMS: Women with a history of gestational diabetes mellitus (GDM) are likely to develop postpartum diabetes mellitus (DM). We examined women in the early stages of pregnancy who were at high risk of postpartum DM progression to establish a follow-up method for early detection. METHODS: We performed the oral glucose tolerance test (OGTT) and identified predictive factors for postpartum impaired glucose tolerance (IGT) or DM in 77 women after GDM, for 2 years after delivery, retrospectively...
March 26, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29596721/substance-use-comorbidity-in-bipolar-disorder-a-qualitative-review-of-treatment-strategies-and-outcomes
#18
REVIEW
Alexandra K Gold, Michael W Otto, Thilo Deckersbach, Louisa G Sylvia, Andrew A Nierenberg, Gustavo Kinrys
BACKGROUND AND OBJECTIVES: Substance use disorders (SUDs) are present in up to 70% of patients with bipolar disorder (BD) and contribute to high rates of disability, morbidity, and treatment non-adherence. Despite this prevalence, few trials have investigated targeted psychosocial interventions for comorbid BD and SUDs. METHODS: Using PubMed and PsycINFO, we conducted a search of the literature up to January 2018 for psychosocial interventions targeted to patients with comorbid BD and SUDs...
April 2018: American Journal on Addictions
https://www.readbyqxmd.com/read/29593946/prevalence-of-type-2-diabetes-mellitus-among-urban-bihari-communities-in-dhaka-bangladesh-a-cross-sectional-study-in-a-minor-ethnic-group
#19
Muhammad Asaduzzaman, Shahanaz Chowdhury, Jahid Hossen Shahed, Mohammad Abdullah Heel Kafi, Md Nazim Uzzaman, Mahfuza Talukder Flowra, Msa Mansur Ahmed
Introduction The prevalence, disease progression, and treatment outcomes for patients with type 2 diabetes vary significantly between ethnic groups. The Bihari community constitutes one of the most vulnerable populations in Bangladesh on the basis of access to health services and other fundamental rights. Our study aimed at finding out the prevalence and risk factors of type 2 diabetes among the Bihari adults in Dhaka city. Methods This cross-sectional community-based study was carried out among stranded Pakistanis (known as Bihari) living in camps in the Mirpur area from July 2014 to June 2015...
January 26, 2018: Curēus
https://www.readbyqxmd.com/read/29593541/a-preliminary-investigation-on-smokeless-tobacco-use-and-its-cognitive-effects-among-athletes
#20
Thomas Zandonai, Cristiano Chiamulera, Alberto Mancabelli, Danilo Falconieri, Marco Diana
Introduction: Among athletes, an increasing use of nicotine via smokeless tobacco has been reported. However, there are currently unanswered questions about whether the use by athletes is due to nicotine's addictive properties and/or to benefits in physical and cognitive performance (e.g., decision-making). In this original article we reported about, (i) snus-induced reinforcing effects among snus-user athletes (Survey) and (ii) the effects of snus on the Iowa Gambling Task (IGT) in snus-user skiers (Experimental study)...
2018: Frontiers in Pharmacology
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