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https://www.readbyqxmd.com/read/28436739/prediabetes-exhibits-decreased-disposition-index-correlated-with-deterioration-of-glycemic-parameters-in-nonobese-japanese-subjects-a-cross-sectional-study-from-medical-examination
#1
Yasutaka Takeda, Yukihiro Fujita, Tsuyoshi Yanagimachi, Jun Honjo, Atsuko Abiko, Mahito Asai, Masakazu Haneda
BACKGROUND: Prediabetes, defined as impaired fasting glucose (IFG) and impaired glucose tolerance (IGT), likely develops to type 2 diabetes mellitus (DM) and independently increases cardiovascular risk. We employed disposition index (DI), a new metabolic parameter indicating the pancreatic beta cell function adjusted for insulin resistance, and investigated whether it could be altered in Japanese population with prediabetes and associated with early glucose intolerance. METHODS: A total of 102 adults who underwent an oral glucose tolerance test at the medical screening were designated to normal glucose tolerance (NGT), IFG, IGT, and DM...
April 24, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28430836/test-retest-reliability-of-common-behavioral-decision-making-tasks
#2
Melissa T Buelow, Wesley R Barnhart
Objective: To examine test-retest reliability of common behavioral decision making tasks. Method: A total of 98 undergraduate students completed two administrations of the Iowa Gambling Task (IGT), Balloon Analogue Risk Task (BART), Columbia Card Task (CCT), and Game of Dice Task (GDT), three weeks apart. Results: The BART, CCT, and GDT showed moderately strong correlations across time. On the IGT, no correlations were seen between Time 1 Trials 1-40 and Time 2 performance; however, weak correlations were observed between Time 1 Trials 41-100 and Time 2 performance...
April 20, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28429468/decision-making-in-obesity-without-eating-disorders-a-systematic-review-and-meta-analysis-of-iowa-gambling-task-performances
#3
REVIEW
J-Y Rotge, C Poitou, P Fossati, J Aron-Wisnewsky, J-M Oppert
BACKGROUND: There is evidence that obesity is associated with impairments in executive functions, such as deficits in decision-making, planning or problem solving, which might interfere with weight loss in obese individuals. We performed a systematic review and meta-analysis of decision-making abilities, as measured with the Iowa gambling task (IGT), in obesity without eating disorders. METHODS: A systematic search was conducted to identify studies comparing IGT performances between groups of obese patients without eating disorders and groups of healthy control groups...
April 21, 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28421080/b-cell-functions-can-be-modulated-by-antimicrobial-peptides-in-rainbow-trout-oncorhynchus-mykiss-novel-insights-into-the-innate-nature-of-b-cells-in-fish
#4
Xu-Jie Zhang, Peng Wang, Nu Zhang, Dan-Dan Chen, Pin Nie, Jia-Le Li, Yong-An Zhang
B cells in fish were recently proven to have potent innate immune activities like macrophages. This inspired us to further explore the innate nature of B cells in fish. Moreover, antimicrobial peptides (AMPs) are representative molecules of innate immunity, and they can modulate the functions of macrophages. These make fish an appropriate model to study the interactions between B cells and AMPs. Interestingly, the results in this study revealed that the IgM(+) and IgT(+) B cells of rainbow trout could express multiple AMP genes, including four cathelicidin genes and one β-defensin gene...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28416367/serum-galanin-concentration-is-increased-in-subjects-with-impaired-glucose-tolerance
#5
Zhenwen Zhang, Penghua Fang, Mei Yu, Yan Wang, Yin Li, Mingyi Shi, Ping Bo, Xuewen Gu, Yan Zhu
OBJECTIVES: Although extensive data have shown that galanin can regulate the food intake and glucose metabolism of animals, little is known regarding the galanin concentration in patients with impaired glucose tolerance (IGT). Therefore, the aims of this study were to investigate whether serum galanin levels and other metabolic parameters are changed in patients with IGT compared with controls with normal glucose tolerance (NGT). METHODS: Data regarding serum galanin levels and relative metabolic parameters were collected in 12 patients with IGT and 12 healthy patients with NGT...
April 14, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28403944/shape-of-the-ogtt-glucose-curve-and-risk-of-impaired-glucose-metabolism-in-the-egir-risc-cohort
#6
Melania Manco, Giuseppe Nolfe, Zoltan Pataky, Lucilla Monti, Francesca Porcellati, Rafael Gabriel, Asimina Mitrakou, Geltrude Mingrone
OBJECTIVE: To study whether the shape of the oral glucose tolerance test (OGTT)-glucose curve is a stable trait over time; it is associated with differences in insulin sensitivity, ß-cell function and risk of impaired fasting glucose (IFG) and glucose tolerance (IGT) in the Relationship between Insulin Sensitivity and Cardiovascular Disease (RISC) cohort. METHODS: OGTT-glucose curve shape was classified as monophasic, biphasic, triphasic and anomalous in 915 individuals...
May 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28394305/a-quadrilateral-geometry-classification-method-and-device-for-femtocell-positioning-networks
#7
Jeich Mar, Tsung Yu Chang, Yu Jie Wang
This article proposes a normalization multi-layer perception (NMLP) geometry classifier to autonomously determine the optimal four femtocell evolved Node Bs (FeNBs), which can use time difference of arrival (TDOA) to measure the location of the macrocell user equipment (MUE) with the lowest GDOP value. The iterative geometry training (IGT) algorithm is designed to obtain the training data for the NMLP geometry classifier. The architecture of the proposed NMLP geometry classifier is realized in the server of the cloud computing platform, to identify the optimal geometry disposition of four FeNBs for positioning the MUE located between two buildings...
April 10, 2017: Sensors
https://www.readbyqxmd.com/read/28391281/inside-out-the-ragbag-of-glucose-intolerance-in-obese-adolescents
#8
Claudia Brufani, Andrea Tura, Giorgio Bedogni, Rosa Luciano, Stefano Sbrignadello, Danilo Fintini, Marco Cappa, Ram Weiss, Melania Manco
BACKGROUND/AIMS: The prevalence of impaired glucose tolerance (IGT) is rising among obese adolescents in parallel with epidemic obesity. In some cases, IGT reverts to normal glucose tolerance (NGT) by the end of puberty. The aims of the present study were to investigate metabolic factors determining changes over time of glucose at 120 min (Glu120) following an oral glucose tolerance test (OGTT), and to verify whether preserved β-cell glucose sensitivity (βCGS) protects against persistent IGT...
April 7, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28386225/attentional-filter-training-but-not-memory-training-improves-decision-making
#9
Marlen Schmicker, Patrick Müller, Melanie Schwefel, Notger G Müller
Decision-making has a high practical relevance for daily performance. Its relation to other cognitive abilities such as executive control and memory is not fully understood. Here we asked whether training of either attentional filtering or memory storage would influence decision-making as indexed by repetitive assessments of the Iowa Gambling Task (IGT). The IGT was developed to assess and simulate real-life decision-making (Bechara et al., 2005). In this task, participants gain or lose money by developing advantageous or disadvantageous decision strategies...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28384881/effect-of-atorvastatin-on-glycaemic-parameters-in-normoglycaemic-and-prediabetic-subjects-a-prospective-panel-study
#10
Sansita Parida, Trupti Rekha Swain, Satya Narayan Routray, Rituparna Maiti
INTRODUCTION: Type 2 diabetes is associated with obesity and dyslipidemia, which are risk factor for cardiovascular disease. With recent FDA approved indications for statins being widened because of its lipid lowering and pleiotropic effects, statins are currently amongst the most widely used drugs in patients with or without diabetes. Although cardiovascular risk is reduced by statin therapy, its association with the development of diabetes is disputed. AIM: This study was conducted to evaluate the effect of Atorvastatin on glycaemic status of normoglycaemic and prediabetic individuals...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28381495/dietary-reversal-of-neuropathy-in-a-murine-model-of-prediabetes-and-the-metabolic-syndrome
#11
Lucy M Hinder, Phillipe D O'Brien, John M Hayes, Carey Backus, Andrew P Solway, Catrina Sims-Robinson, Eva L Feldman
Patients with the metabolic syndrome, defined as obesity, dyslipidemia, hypertension, and impaired glucose tolerance (IGT), can develop the same macro- and microvascular complications as patients with type 2 diabetes, including peripheral neuropathy. In type 2 diabetes, glycemic control has little effect on the development and progression of peripheral neuropathy, suggesting that other metabolic syndrome components may contribute to the presence of neuropathy. A parallel phenomenon is observed in patients with prediabetes and the metabolic syndrome, where improvement in weight and dyslipidemia more closely correlates with restoration of nerve function than improvement in glycemic status...
April 5, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28372564/low-apoa-i-is-associated-with-insulin-resistance-in-patients-with-impaired-glucose-tolerance-a-cross-sectional-study
#12
Xiaomeng Feng, Xia Gao, Zhi Yao, Yuan Xu
BACKGROUND: Low apolipoprotein A-I (apoA-I) is an independent risk factor for atherosclerotic cardiovascular diseases. Insulin resistance predicts the progression of abnormal glucose metabolism, which is the main cause of atherosclerotic cardiovascular disease. In this study, we assessed the potential association between apoA-I levels and insulin resistance in patients with impaired glucose tolerance (IGT) and the possible link between apoA-I and IGT. METHODS: This study evaluated a cross-sectional study of 108 participants with impaired glucose tolerance (IGT group) and 84 controls (control group)...
April 4, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28362163/ties-that-bond-youth-sport-as-a-vehicle-for-social-identity-and-positive-youth-development
#13
Mark W Bruner, Shea M Balish, Christopher Forrest, Sarah Brown, Kristine Webber, Emily Gray, Matthew McGuckin, Melanie R Keats, Laurene Rehman, Christopher A Shields
An emerging area of research has focused on understanding how the group dynamics of a sport team influence positive youth development (PYD). The identities that youth form through their membership in sport teams (i.e., social identities) have been found to influence teammate behavior and team performance. Yet, minimal work exists on social identity and PYD in youth sport. PURPOSE: The purpose of this study was to investigate the relationship between social identity and PYD in sport. METHOD: Youth engaged in recreational sport (N = 219; Mage = 11...
March 31, 2017: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/28361462/ppar-%C3%AE-agonist-fenofibrate-reduces-insulin-resistance-in-impaired-glucose-tolerance-patients-with-hypertriglyceridemia-a-cross-sectional-study
#14
Xiaomeng Feng, Xia Gao, Yumei Jia, Yuan Xu
INTRODUCTION: Peroxisome proliferator-activated receptor-α (PPAR-α) agonists can regulate metabolism and protect the cardiovascular system. This study investigated the effects of PPAR-α agonist fenofibrate on insulin resistance in patients with impaired glucose tolerance (IGT). METHODS: This research evaluated cross-sectional and interventional studies. 191 subjects with IGT were divided into a hypertriglyceridemia group (HTG group, n = 118) and a normal triglyceride (TG) group (NTG group, n = 73)...
April 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28351091/plasma-betatrophin-levels-of-subjects-classified-with-normal-impaired-and-diabetic-glucose-tolerance-and-subjects-with-impaired-fasting-glucose
#15
Sibel Ozyazgan, Burak Onal, Eda Merve Kurtulus, Hafize Uzun, Gokhan Akkan, Dildar Konukoglu
This study was aimed to investigate whether betatrophin shows glucose intolerance or not. To access the plasma betatrophin levels after basal and glucose load, groups were classified as normal glucose tolerance (NGT), impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and diabetic glucose tolerance (DGT) according to WHO 2012 criteria. An oral glucose tolerance test was performed on age-matched subjects (n=220) with a body mass index (BMI)<27 kg/m(2). Subjects were categorized as normoglycemic (n=55), IFG (n=50), IGT (n=60), and DM (n=55) according to the WHO criteria...
March 28, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28345542/association-between-self-reported-snoring-and-prediabetes-among-adults-aged-40-years-and-older-without-diabetes
#16
Hai-Bin Wang, Wen-Hua Yan, Jing-Tao Dou, Zhao-Hui Lu, Bao-An Wang, Yi-Ming Mu
BACKGROUND: Several previous studies have shown that snoring is associated with glucose metabolism and the development of diabetes, but rare study has shown the association between snoring frequency and prediabetes, particularly in China. We hypothesized that individuals who snore might have a higher risk of prediabetes. This study aimed to investigate the association between self-reported snoring and prediabetes in a Chinese population. METHODS: A cross-sectional study was performed in three large communities of Beijing from December 2011 to August 2012 by recruiting individuals aged ≥40 years old...
April 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28325542/the-influence-of-ethnicity-and-glucose-tolerance-status-on-subjective-hunger-sensations-and-prospective-food-intake-in-overweight-and-obese-asian-and-european-australians
#17
Leilani Muhardi, Yun Zhao, Vicky Solah, Susan Fyfe, Mario J Soares
AIMS: To examine the influence of ethnicity and glucose tolerance status on subjective sensations and food intake in overweight/obese Asian and European Australians. METHODS: 18 Asians and 26 Europids were classified as normal glucose tolerance (NGT) and impaired glucose tolerance (IGT) based on serial measures of finger-prick glucose following an oral glucose tolerance test (OGTT). Subjective sensations of hunger and satiety were measured before and every 15min after the OGTT using a visual analogue scale (VAS)...
March 6, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28317426/the-influence-of-social-identity-on-self-worth-commitment-and-effort-in-school-based-youth-sport
#18
Luc J Martin, Danny Balderson, Michael Hawkins, Kathleen Wilson, Mark W Bruner
​​​The current study examined the influence of social identity for individual perceptions of self-worth, commitment, and effort in school-based youth athletes. Using a prospective research design, 303 athletes (Mage = 14.89, SD = 1.77; 133 female) from 27 sport teams completed questionnaires at 2 time points (T1 - demographics, social identity; T2 - self-worth, commitment, effort) during an athletic season. Multilevel analyses indicated that at the individual level, the social identity dimension of in-group ties (IGT) predicted commitment (b = 0...
March 18, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28316001/associations-of-polymorphisms-in-the-candidate-genes-for-alzheimer-s-disease-bin1-clu-cr1-and-picalm-with-gestational-diabetes-and-impaired-glucose-tolerance
#19
Gabriela Vacínová, D Vejražková, P Lukášová, O Lischková, K Dvořáková, R Rusina, I Holmerová, H Vaňková, J Včelák, B Bendlová, M Vaňková
Alzheimer's disease (AD) is the most common type of dementia, with a prevalence that is rising every year. AD is associated with type 2 diabetes mellitus (T2DM) and insulin resistance, and is therefore sometimes called "type 3 diabetes mellitus". The aim of this study was to examine whether the variants of some candidate genes involved in the development of AD, namely BIN1 (rs744373), CLU (rs11136000), CR1 (rs3818361), and PICALM (rs3851179), are related to several disorders of glucose metabolism-gestational diabetes (GDM), T2DM and impaired glucose tolerance (IGT)...
March 18, 2017: Molecular Biology Reports
https://www.readbyqxmd.com/read/28303534/chronic-tobacco-smoking-on-psychopathological-symptoms-impulsivity-and-cognitive-deficits-in-hiv-infected-individuals
#20
Linda Chang, Ahnate Lim, Eric Lau, Daniel Alicata
HIV-infected individuals (HIV+) has 2-3 times the rate of tobacco smoking than the general population, and whether smoking may lead to greater psychiatric symptoms or cognitive deficits remains unclear. We evaluated the independent and combined effects of being HIV+ and chronic tobacco-smoking on impulsivity, psychopathological symptoms and cognition. 104 participants [27 seronegative (SN)-non-Smokers, 26 SN-Smokers, 29 HIV+ non-Smokers, 22 HIV+ Smokers] were assessed for psychopathology symptoms (Symptom Checklist-90, SCL-90), depressive symptoms (Center for Epidemiologic Studies-Depression Scale, CES-D), impulsivity (Barratt Impulsiveness Scale, BIS), decision-making (The Iowa Gambling Task, IGT, and Wisconsin Card Sorting Test, WCST), and cognition (seven neurocognitive domains)...
March 16, 2017: Journal of Neuroimmune Pharmacology: the Official Journal of the Society on NeuroImmune Pharmacology
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