keyword
MENU ▼
Read by QxMD icon Read
search

Samuel

keyword
https://www.readbyqxmd.com/read/28109199/functional-magnetic-resonance-imaging-in-dermatology-the-skin-the-brain-and-the-invisible
#1
REVIEW
Simon M Mueller, Samuel Hogg, Jannis Mueller, Shane McKie, Peter Itin, Julia Reinhardt, Christopher E M Griffiths, C Elise Kleyn
The skin and brain have a close bi-directional anatomical and functional connection. Historically, the skin-brain axis and the brain-skin axis have been well described. However, brain function in this context has only recently been demystified with the introduction of functional neuroimaging in dermatology. Functional neuroimaging, especially functional magnetic resonance imaging (fMRI), allows indirect visualisation of brain function. This review looks back to the beginnings of functional neuroimaging in dermatology, summarises the currently available dermatology-related fMRI-studies and discusses the potential future role of fMRI as a stratifying tool in clinical dermatology and in the development of novel therapies...
January 21, 2017: Experimental Dermatology
https://www.readbyqxmd.com/read/28108676/can-work-make-you-mentally-ill-a-systematic-meta-review-of-work-related-risk-factors-for-common-mental-health-problems
#2
REVIEW
Samuel B Harvey, Matthew Modini, Sadhbh Joyce, Josie S Milligan-Saville, Leona Tan, Arnstein Mykletun, Richard A Bryant, Helen Christensen, Philip B Mitchell
It has been suggested that certain types of work may increase the risk of common mental disorders, but the exact nature of the relationship has been contentious. The aim of this paper is to conduct the first comprehensive systematic meta-review of the evidence linking work to the development of common mental health problems, specifically depression, anxiety and/or work-related stress and to consider how the risk factors identified may relate to each other. MEDLINE, PsychInfo, Embase, the Cochrane Collaboration and grey literature databases were systematically searched for review articles that examined work-based risk factors for common mental health problems...
January 20, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28108654/revealing-the-role-of-the-product-metal-in-dna-polymerase-%C3%AE-catalysis
#3
Lalith Perera, Bret D Freudenthal, William A Beard, Lee G Pedersen, Samuel H Wilson
DNA polymerases catalyze a metal-dependent nucleotidyl transferase reaction during extension of a DNA strand using the complementary strand as a template. The reaction has long been considered to require two magnesium ions. Recently, a third active site magnesium ion was identified in some DNA polymerase product crystallographic structures, but its role is not known. Using quantum mechanical/ molecular mechanical calculations of polymerase β, we find that a third magnesium ion positioned near the newly identified product metal site does not alter the activation barrier for the chemical reaction indicating that it does not have a role in the forward reaction...
January 20, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28108142/identifying-mronj-affected-bone-with-digital-fusion-of-functional-imaging-fi-and-cone-beam-computed-tomography-cbct-case-reports-and-hypothesis
#4
Gayathri Subramanian, Evelyne Kalyoussef, Meredith Blitz-Goldstein, Jessenia Guerrero, Nasrin Ghesani, Samuel Y P Quek
Surgical debridement of medication-related osteonecrosis of the jaw (MRONJ) lesions is far less predictable than lesion resection. Margins for surgical debridement are guided by surrogate markers of bone viability, such as bleeding and bone fluorescence, which limit debridement to visibly necrotic bone. In contrast, surgical resection is extensive, including a substantial portion of surrounding bone. The concept that the MRONJ lesion is a composite of affected but viable ("compromised") and necrotic bone is supported by histopathological data...
November 28, 2016: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28107796/social-and-structural-factors-related-to-hiv-risk-among-truck-drivers-passing-through-the-iringa-region-of-tanzania
#5
Anjalee Kohli, Deanna Kerrigan, Heena Brahmbhatt, Samuel Likindikoki, Justin Beckham, Ard Mwampashi, Jessie Mbwambo, Caitlin E Kennedy
Truck drivers and their assistants have been identified as groups at higher risk for HIV infection. We sought to identify and describe the social and structural factors that may contribute to HIV risk among truck drivers who visit rest stops in Iringa, Tanzania, a region characterized by high levels of migration and mobility. This analysis was part of a comprehensive strategic assessment to examine HIV risk factors in Iringa. This analysis focuses on 11 in-depth interviews with truck drivers and a transport owner...
January 20, 2017: AIDS Care
https://www.readbyqxmd.com/read/28107792/noteworthy-literature-published-in-2016-for-abdominal-organ-transplant-anesthesiologists
#6
Jeron Zerillo, Sang Kim, Bryan Hill, Samuel DeMaria, Tetsuro Sakai
More than 400 peer-reviewed publications on the topic of pancreas transplantation, more than 400 on intestine transplantation, and more than 3000 on renal transplantation were published in 2016. This review will highlight the most pertinent literature for anesthesiologists caring for patients undergoing non-liver abdominal organ transplantation. This review is the second part in an annual series to review relevant contributions in the field of abdominal organ transplantation focusing on pancreas, intestine, and renal transplantation...
January 1, 2017: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28107386/regulation-of-pi-2b-pilus-expression-in-hypervirulent-streptococcus-agalactiae-st-17-bm110
#7
Bruno Périchon, Noémi Szili, Laurence du Merle, Isabelle Rosinski-Chupin, Myriam Gominet, Samuel Bellais, Claire Poyart, Patrick Trieu-Cuot, Shaynoor Dramsi
The widely spread Streptococcus agalactiae (also known as Group B Streptococcus, GBS) "hypervirulent" ST17 clone is strongly associated with neonatal meningitis. The PI-2b locus is mainly found in ST17 strains but is also present in a few non ST17 human isolates such as the ST-7 prototype strain A909. Here, we analysed the expression of the PI-2b pilus in the ST17 strain BM110 as compared to the non ST17 A909. Comparative genome analyses revealed the presence of a 43-base pair (bp) hairpin-like structure in the upstream region of PI-2b operon in all 26 ST17 genomes, which was absent in the 8 non-ST17 strains carrying the PI-2b locus...
2017: PloS One
https://www.readbyqxmd.com/read/28107353/weight-perturbation-alters-leptin-signal-transduction-in-a-region-specific-manner-throughout-the-brain
#8
Michael V Morabito, Yann Ravussin, Bridget R Mueller, Alicja A Skowronski, Kazuhisa Watanabe, Kylie S Foo, Samuel X Lee, Anders Lehmann, Stephan Hjorth, Lori M Zeltser, Charles A LeDuc, Rudolph L Leibel
Diet-induced obesity (DIO) resulting from consumption of a high fat diet (HFD) attenuates normal neuronal responses to leptin and may contribute to the metabolic defense of an acquired higher body weight in humans; the molecular bases for the persistence of this defense are unknown. We measured the responses of 23 brain regions to exogenous leptin in 4 different groups of weight- and/or diet-perturbed mice. Responses to leptin were assessed by quantifying pSTAT3 levels in brain nuclei 30 minutes following 3 mg/kg intraperitoneal leptin...
2017: PloS One
https://www.readbyqxmd.com/read/28107278/impact-of-early-surgery-and-immunosuppression-on-crohn-s-disease-disabling-outcomes
#9
Fernando Magro, Cláudia C Dias, Rosa Coelho, Paula M Santos, Samuel Fernandes, Cidalina Caetano, Ângela Rodrigues, Francisco Portela, Ana Oliveira, Paula Ministro, Eugénia Cancela, Ana I Vieira, Rita Barosa, José Cotter, Pedro Carvalho, Isabelle Cremers, Daniel Trabulo, Paulo Caldeira, Artur Antunes, Isadora Rosa, Joana Moleiro, Paula Peixe, Rita Herculano, Raquel Gonçalves, Bruno Gonçalves, Helena Tavares Sousa, Luís Contente, Henrique Morna, Susana Lopes
BACKGROUND AND AIMS: The definition of early therapeutic strategies to control Crohn's disease aggressiveness and prevent recurrence is key to improve clinical practice. This study explores the impact of early surgery and immunosuppression onset in the occurrence of disabling outcomes. METHODS: This was a multicentric and retrospective study with 754 patients with Crohn's disease, who were stratified according to the need for an early surgery (group S) or not (group I) and further divided according to the time elapsed from the beginning of the follow-up to the start of immunosuppression therapy...
February 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28107243/robotic-guidance-for-s2-alar-iliac-screws-in-spinal-deformity-correction
#10
S Samuel Bederman, Peter Hahn, Vincent Colin, P Douglas Kiester, Nitin N Bhatia
STUDY DESIGN: A retrospective cohort study of patients who underwent S2-alar-iliac (S2AI) screw insertion using robotic guidance in long constructs for spinal deformity correction extending to the sacrum performed at a single institution. OBJECTIVE: To assess and evaluate the feasibility and accuracy of robotic guidance for S2AI screw insertion. SUMMARY OF BACKGROUND DATA: Pelvic fixation has become a common adjunct to long fusions extending to the sacrum...
February 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28107088/the-national-eye-survey-of-trinidad-and-tobago-nestt-rationale-objectives-and-methodology
#11
Tasanee Braithwaite, Neville Q Verlander, Debra Bartholomew, Petra Bridgemohan, Kevin McNally, Allana Roach, Subash Sharma, Deo Singh, Konrad Pesudovs, Surujpal Teelucksingh, Christine Carrington, Samuel Ramsewak, Rupert Bourne
PURPOSE: This paper describes the rationale, study design and procedures of the National Eye Survey of Trinidad and Tobago (NESTT). The main objective of this survey is to obtain prevalence estimates of vision impairment and blindness for planning and policy development. METHODS: A population-based, cross-sectional survey was undertaken using random multistage cluster sampling, with probability-proportionate-to-size methods. Eligible participants aged 5 years and older were sampled from the non-institutional population in each of 120 cluster segments...
January 20, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28105963/prevalence-and-heritability-of-early-childhood-caries-among-monozygotic-and-dizygotic-twins
#12
Anuradha Kuppan, Steven Rodrigues, Victor Samuel, Mahesh Ramakrishnan, Hassan S Halawany, Nimmi B Abraham, Vimal Jacob, Sukumaran Anil
Deciphering the relative importance of genetic and environmental factors, which play a major role in the prevalence of early childhood caries (ECC), can help clinicians with planning a long-term preventive treatment. The objective of the study was to determine the prevalence and heritability of ECC among monozygotic (MZ) and dizygotic (DZ) twins in Chennai, India, in the year 2013. A cross-sectional study was designed to estimate the prevalence of ECC among twins. Zygosity classification for the survey framework was adapted from a highly accurate parental report questionnaire pertaining to the physical similarity between twins...
February 2017: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/28105868/why-are-older-people-often-so-responsible-and-considerate-even-when-their-future-seems-limited-a-systematic-review
#13
Simon A Moss, Samuel G Wilson
Socioemotional selectivity theory assumes that older individuals tend to perceive their identity or life as limited in time and, therefore, prioritize meaningful relationships. Yet, other research shows that people who perceive their identity as limited in time tend to behave impulsively-contrary to the behavior of many older individuals. To redress this paradox, this article reports a systematic review, comprising 86 papers, that examined the consequences of whether individuals perceive their identity as limited or enduring...
January 1, 2017: International Journal of Aging & Human Development
https://www.readbyqxmd.com/read/28105637/preschoolers-continually-adjust-their-epistemic-trust-based-on-an-informant-s-ongoing-accuracy
#14
Samuel Ronfard, Jonathan D Lane
Children aged 4-7 years (N = 120) played four rounds of a find-the-sticker game. For each round, an informant looked into two cups and made a claim about which cup held a sticker. At the end of each round, children guessed the sticker's location, and then the sticker's actual location was revealed. For three of the rounds, the informant accurately reported the sticker's location. But critically, for one round-either Round 1, 2, or 3-she was inaccurate. Children continually adjusted their trust in the informant as they obtained more information about her accuracy...
January 20, 2017: Child Development
https://www.readbyqxmd.com/read/28105334/chronic-kidney-disease-in-children-and-the-role-of-epigenetics-future-therapeutic-trajectories
#15
Samuel N Uwaezuoke, Henrietta U Okafor, Vivian N Muoneke, Odutola I Odetunde, Chioma L Odimegwu
Global differences in the observed causes of chronic kidney disease (CKD) in children are well documented and are attributed to dissimilarities in clime, race, hereditary, and ancestry. Thus, familial clustering and disparities in CKD prevalence rates across ethnic and racial groups indicate that the progression of renal disease has a strong genetic component. Mammalian studies have demonstrated a feasible nexus between nutrition and non-genetic exposure (around the time of conception and in epigenetic changes) in the expression of major genes identified in renal organogenesis...
December 2016: Biomedical Reports
https://www.readbyqxmd.com/read/28104921/effects-of-gold-nanoparticles-on-lipid-packing-and-membrane-pore-formation
#16
Anupama Bhat, Lance W Edwards, Xiao Fu, Dillon L Badman, Samuel Huo, Albert J Jin, Qi Lu
Gold nanoparticles (AuNPs) have been increasingly integrated in biological systems, making it imperative to understand their interactions with cell membranes, the first barriers to be crossed to enter cells. Herein, liposomes composed of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) as a model membrane system were treated with citrate stabilized AuNPs from 5 to 30 nm at various concentrations. The fluorescence shifts of Laurdan probes reveal that AuNPs in general made liposomes more fluidic. The increased fluidity is expected to result in an increased surface area, and thus liposome shape changes from circular to less circular, which was further confirmed with fluorescence microscopy...
December 26, 2016: Applied Physics Letters
https://www.readbyqxmd.com/read/28104718/boncat-enables-time-resolved-analysis-of-protein-synthesis-in-native-plant-tissue
#17
Weslee Glenn, Shannon E Stone, Samuel H Ho, Michael J Sweredoski, Annie Moradian, Sonja Hess, Julia Bailey-Serres, David A Tirrell
Proteomic plasticity undergirds stress responses in plants, and understanding such responses requires accurate measurement of the extent to which proteins levels are adjusted to counter external stimuli. Here, we adapt bioorthogonal non-canonical amino acid tagging (BONCAT) to interrogate protein synthesis in vegetative Arabidopsis thaliana seedlings. BONCAT relies on the translational incorporation of a non-canonical amino acid (ncAA) probe into cellular proteins. In this study, the probe is the methionine surrogate azidohomoalanine (Aha), which carries a reactive azide moiety in its amino acid side chain...
January 19, 2017: Plant Physiology
https://www.readbyqxmd.com/read/28104577/investigating-subjective-experience-and-the-influence-of-weather-among-individuals-with-fibromyalgia-a-content-analysis-of-twitter
#18
Pari Delir Haghighi, Yong-Bin Kang, Rachelle Buchbinder, Frada Burstein, Samuel Whittle
BACKGROUND: Little is understood about the determinants of symptom expression in individuals with fibromyalgia syndrome (FMS). While individuals with FMS often report environmental influences, including weather events, on their symptom severity, a consistent effect of specific weather conditions on FMS symptoms has yet to be demonstrated. Content analysis of a large number of messages by individuals with FMS on Twitter can provide valuable insights into variation in the fibromyalgia experience from a first-person perspective...
January 19, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28103959/validation-of-a-case-definition-for-pediatric-brain-injury-using-administrative-data
#19
Jane McChesney-Corbeil, Karen Barlow, Hude Quan, Guanmin Chen, Samuel Wiebe, Nathalie Jette
BACKGROUND: Health administrative data are a common population-based data source for traumatic brain injury (TBI) surveillance and research; however, before using these data for surveillance, it is important to develop a validated case definition. The objective of this study was to identify the optimal International Classification of Disease , edition 10 (ICD-10), case definition to ascertain children with TBI in emergency room (ER) or hospital administrative data. We tested multiple case definitions...
January 20, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/28103930/trends-in-hospital-admissions-due-to-antidepressant-related-adverse-drug-events-from-2001-to-2011-in-the-u-s
#20
Harish S Parihar, Hongjun Yin, Jennifer L Gooch, Shari Allen, Samuel John, Jianwei Xuan
BACKGROUND: Depression is a prevalent mental health disorder and the fourth leading cause of disability in the world as per the World Health Organization. Use of antidepressants can lead to adverse drug events (ADEs), defined as any injury resulting from medication use. This study aimed to examine changes in hospital admissions due to antidepressant-related ADEs (ArADEs) among different socio-demographic groups and changes in lengths of stay (LOS) and hospital charges in ArADE admissions from 2001 to 2011...
January 19, 2017: BMC Health Services Research
keyword
keyword
86831
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"