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Vaginal yeast

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https://www.readbyqxmd.com/read/27915337/quercetin-assists-fluconazole-to-inhibit-biofilm-formations-of-fluconazole-resistant-candida-albicans-in-in-vitro-and-in-vivo-antifungal-managements-of-vulvovaginal-candidiasis
#1
Mei Gao, Hui Wang, LiJuan Zhu
BACKGROUND: Vulvovaginal candidiasis (VVC) is a common gynecological disease. Candida albicans is believed to be mainly implicated in VVC occurrence, the biofilm of which is one of the virulence factors responsible for resistance to traditional antifungal agents especially to fluconazole (FCZ). Quercetin (QCT) is a dietary flavonoid and has been demonstrated to be antifungal against C. albicans biofilm. METHODS: 17 C. albicans isolates including 15 clinical ones isolated from VVC patients were employed to investigate the effects of QCT and/or FCZ on the inhibition of C...
November 30, 2016: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/27847193/extremely-low-gestational-age-and-very-low-birthweight-for-gestational-age-are-risk-factors-for-autism-spectrum-disorder-in-a-large-cohort-study-of-10-year-old-children-born-at-23-27-weeks-gestation
#2
Robert M Joseph, Steven J Korzeniewski, Elizabeth N Allred, T Michael O'Shea, Tim Heeren, Jean A Frazier, Janice Ware, Deborah Hirtz, Alan Leviton, Karl Kuban
BACKGROUND: No prospective cohort study of high-risk children has used rigorous exposure assessment and optimal diagnostic procedures to examine the perinatal antecedents of autism spectrum disorder separately among those with and without cognitive impairment. OBJECTIVE: We sought to identify perinatal factors associated with increased risk for autism spectrum disorder with and without intellectual disability (intelligence quotient <70) in children born extremely preterm...
November 12, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27833516/utility-of-laboratory-diagnosis-for-confirmation-of-the-syndromic-case-management-in-married-indian-women-with-vaginal-discharge
#3
Prabhav Aggarwal, Sonali Bhattar, Satyendra Kumar Sahani, Preena Bhalla
OBJECTIVE: WHO and NACO recommend treatment of STIs/RTIs on the basis syndromic case management (SCM), even without laboratory confirmation, which may lead to over-treatment. Thus, this study was conducted to evaluate the utility of laboratory diagnosis for confirmation of patients with vaginal discharge diagnosed on the basis of SCM. METHODOLOGY: 234 married women in reproductive age group, diagnosed as having vaginal discharge syndrome were included. Normal saline wet-mount slide preparations were made for detection of motile trichomonads...
October 2016: International Journal of Health Sciences
https://www.readbyqxmd.com/read/27788740/-study-on-the-production-of-igg-derived-from-vaginal-epithelial-cells-and-the-effect-of-anti-candida-albicans
#4
X X Niu, T Li, Z H Liu
Objective: To investigate the function of IgG secreted by vaginal epithelial cells in natural resistance to vulvovaginal candidiasis. Methods: (1)Immunohistochemical method was used to determine the expression of IgG secreted by normal vaginal epithelial cells VK2/E6E7.(2)Samples were divided into three groups by different proportions of VK2/E6E7 cells to Candida albicans ,including Candida albicans: VK2/E6E7 cells were 1∶10, 1∶1[yeast+ cells(1∶10)group and yeast+ cells(1∶1)group]and VK2/E6E7 cells as blank control group...
October 25, 2016: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/27751723/antifungal-effects-of-lavandula-binaludensis-and-cuminum-cyminum-essential-oils-against-candida-albicans-strains-isolated-from-patients-with-recurrent-vulvovaginal-candidiasis
#5
M H Minooeianhaghighi, L Sepehrian, H Shokri
OBJECTIVE: Recurrent vulvovaginal candidiasis (RVVC), which affects approximately 5% of women of reproductive age, is defined as 4 or more episodes of symptomatic Candida vaginitis within a year. The purposes of this study were to determine the chemical compositions and antifungal susceptibility of Cuminum cyminum (C. cyminum) and Lavandula binaludensis (L. binaludensis) essential oils and their combination against Candida albicans (C. albicans) strains isolated from patients with RVVC...
October 14, 2016: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/27744307/genetic-diversity-of-the-hwp1-gene-and-his3-ef3-cdc3-microsatellites-and-antifungal-susceptibility-profiles-of-candida-albicans-isolates-from-yaound%C3%A3-hiv-infected-patients
#6
Thierry Kammalac Ngouana, Pascal Drakulovski, Donika Krasteva, Rufin Kuipou Toghueo, Charles Kouanfack, Jacques Reynes, Eric Delaporte, Fabrice Fekam Boyom, Michèle Mallié, Sébastien Bertout
The molecular epidemiology and the antifungal susceptibility profiles of Candida albicans are scarce in Cameroon. Authors studied the genetic diversity and the antifungal susceptibility of C. albicans isolates from Yaoundé HIV-infected patients. Clinical isolates were obtained by mycological diagnosis of oropharyngeal swabs, stools, urine, and vaginal swabs from patients. C. albicans isolates were confirmed by the Light cycler real-time PCR of the ITS1 region of the 5.8s ribosomal DNA. The ABC genotypes and the Hwp1 gene amplification were carried out with specific primers...
October 14, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/27741168/the-in-vitro-effectiveness-of-lactobacillus-fermentum-against-different-candida-species-compared-with-broadly-used-azoles
#7
Francesca Deidda, Angela Amoruso, Stefania Nicola, Teresa Graziano, Marco Pane, Serena Allesina, Elisabetta Raiteri, Mario Del Piano, Luca Mogna
GOALS: To investigate the possible use of Lactobacillus strains in the prophylaxis and/or adjuvant therapy of acute vulvovaginal candidiasis and other vaginal infections sustained by Candida yeasts. BACKGROUND: The incidence of Candida infections has substantially increased in recent years. Treatment of vaginal infections with lactobacilli has a long tradition, starting with Döderlein's description of the vaginal microbiota. MATERIALS AND METHODS: We assessed the activity of serially diluted fluconazole and miconazole (from 3 ng/mL to 1 mg/mL) against Candida strains...
November 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27741167/in-vitro-activity-of-lactobacillus-fermentum-lf5-against-different-candida-species-and-gardnerella-vaginalis-a-new-perspective-to-approach-mixed-vaginal-infections
#8
Francesca Deidda, Angela Amoruso, Serena Allesina, Marco Pane, Teresa Graziano, Mario Del Piano, Luca Mogna
GOALS: This study was undertaken to demonstrate the ability of Lactobacillus fermentum LF5 (DSM 32277) to inhibit in vitro different Candida species and Gardnerella vaginalis to weigh its potential effectiveness even in mixed vaginal infections. BACKGROUND: A wide female population is suffering from various vulvovaginal infections. These diseases are often associated with a decrease in the concentration of Lactobacilli in the vagina. Mixed vaginal infections represent >20% of women with vulvovaginal infection...
November 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27679703/microdilution-in-vitro-antifungal-susceptibility-patterns-of-candida-species-from-mild-cutaneous-to-bloodstream-infections
#9
Elham Rezazadeh, Azar Sabokbar, Maryam Moazeni, Mohammad Sadegh Rezai, Hamid Badali
BACKGROUND: Candida species, as opportunistic organisms, can cause various clinical manifestations, ranging from mild cutaneous infections to systemic candidiasis in otherwise healthy individuals. Remarkably, the incidence and mortality rates of candidemia have significantly increased worldwide, even after advances in medical interventions and the development of novel antifungal drugs. OBJECTIVES: Given the possible resistance to antifungal agents, susceptibility testing can be useful in defining the activity spectrum of antifungals and determining the appropriate treatment regime...
July 2016: Jundishapur Journal of Microbiology
https://www.readbyqxmd.com/read/27568869/sensitivity-of-candida-albicans-to-essential-oils-are-they-an-alternative-to-antifungal-agents
#10
E Bona, S Cantamessa, M Pavan, G Novello, N Massa, A Rocchetti, G Berta, E Gamalero
AIMS: Candida albicans is an important opportunistic pathogen, responsible for the majority of yeast infections in humans. Essential oils, extracted from aromatic plants, are well-known antimicrobial agents, characterized by a broad spectrum of activities, including antifungal properties. The aim of this work was to assess the sensitivity of 30 different vaginal isolated strains of C. albicans to 12 essential oils, compared to the three main used drugs (clotrimazole, fluconazole and itraconazole)...
December 2016: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/27552787/vulvovaginal-candidiasis-in-pregnant-women-and-its-importance-for-candida-colonization-of-newborns
#11
Liliya G Zisova, Anastasia A Chokoeva, Georgi I Amaliev, Penka V Petleshkova, Tsonka М Miteva-Katrandzhieva, Maya B Krasteva, Ekaterina H Uchikova, Andrei H Kouzmanov, Zoya V Ivanova
UNLABELLED: Vulvovaginal candidiasis is the second most common cause of vaginitis worldwide (after bacterial candidiasis). Maternal vulvovaginal candidiasis is a major risk factor for Candida colonization and infection of the infant where prognosis depends on different predisposing factors. The aim of this study was to determine the incidence and the etiological structure of vulvovaginal candidiasis in pregnant women and its impact on Candida colonization of newborns. MATERIALS AND METHODS: Samples of vaginal secretions from 80 healthy pregnant women who were clinically suspicious for Candida vaginitis were collected within 48 hours before delivery...
April 2016: Folia Medica
https://www.readbyqxmd.com/read/27540323/yeast-infection-and-diabetes-mellitus-among-pregnant-mother-in-malaysia
#12
Iylia Liyana Sopian, Sa'adiah Shahabudin, Mowaffaq Adam Ahmed, Leslie Than Thian Lung, Doblin Sandai
BACKGROUND: Vaginal yeast infection refers to irritation of the vagina due to the presence of opportunistic yeast of the genus Candida (mostly Candida albicans). About 75% of women will have at least one episode of vaginal yeast infection during their lifetime. Several studies have shown that pregnancy and uncontrolled diabetes increase the infection risk. Reproductive hormone fluctuations during pregnancy and elevated glucose levels characteristic of diabetes provide the carbon needed for Candida overgrowth and infection...
January 2016: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/27465873/-effects-of-antimicrobial-peptide-ll-37-expressed-and-purified-from-prokaryotes-in-the-murine-model-of-vaginal-candidiasis
#13
F Wang, Y Huo, L R Yin, B Sun, P P Zhang
OBJECTIVE: To study the effects of antimicrobial peptide LL-37 expressed and purified from prokaryotes on candida albicans growth. METHODS: (1)Thirty female Kunming mice were treated with estrogen and white candida yeast suspension were poured into vagina to establish a vulvovaginal candidiasis(VVC)murine model. After successful establishing the VVC mouse model, mice were randomly sorted into test group(n=15)and control group(n=15). Suspension(30 μl, 100 μg/ml)of recombinant peptide LL-37 expressed and purified in Prokaryotes was given by intravaginal administration to the test group for 5 days, while the same amount of phosphate buffered saline(PBS)was given to the control group...
July 25, 2016: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/27435998/therapeutic-activity-of-a-saccharomyces-cerevisiae-based-probiotic-and-inactivated-whole-yeast-on-vaginal-candidiasis
#14
Eva Pericolini, Elena Gabrielli, Nathalie Ballet, Samuele Sabbatini, Elena Roselletti, Amélie Cayzeele Decherf, Fanny Pélerin, Eugenio Luciano, Stefano Perito, Peter Jüsten, Anna Vecchiarelli
Vulvovaginal candidiasis is the most prevalent vaginal infection worldwide and Candida albicans is its major agent. Vulvovaginal candidiasis is characterized by disruption of the vaginal microbiota composition, as happens following large spectrum antibiotic usage. Recent studies support the effectiveness of oral and local probiotic treatment for prevention of recurrent vulvovaginal candidiasis. Saccharomyces cerevisiae is a safe yeast used as, or for, the production of ingredients for human nutrition and health...
July 19, 2016: Virulence
https://www.readbyqxmd.com/read/27415762/highlights-regarding-host-predisposing-factors-to-recurrent-vulvovaginal-candidiasis-chronic-stress-and-reduced-antioxidant-capacity
#15
Luciene Akimoto-Gunther, Patrícia de Souza Bonfim-Mendonça, Gisele Takahachi, Mary Mayumi T Irie, Sônia Miyamoto, Márcia Edilaine Lopes Consolaro, Terezinha I Estivalet Svidzinsk
We studied host factors that could predispose women to develop recurrent vulvovaginal candidiasis (RVVC), including glycemia, insulin resistance, chronic stress, antioxidant capacity, overall immune status, local inflammation and vaginal microbiota. The presence of yeasts in vaginal culture was screened in 277 women, with or without signs and symptoms of VVC and RVVC. The presence of an inflammatory process and microbiota were analyzed through vaginal bacterioscopy and cervical-vaginal cytology, respectively...
2016: PloS One
https://www.readbyqxmd.com/read/27167765/-identification-and-in-vitro-antifungal-susceptibility-of-vaginal-candida-spp-isolates-to-fluconazole-clotrimazole-and-nystatin
#16
M C Diaz, R Camponovo, I Araya, A Cerda, M P Santander, A J Carrillo-Muñoz
OBJECTIVE: The aim of this study was to identify and determine the in vitro antifungal susceptibility testing to clotrimazole, fluconazole, and nystatin of 145 clinical isolates of Candida spp. METHODS: M27-A3 microdilution method was used to determine minimal inhibitory concentrations (MIC) and partial MICs (MIC50 and MIC90) of drugs. A total of 145 isolates were studied, 126 were C. albicans, 16 C. glabrata, 2 C. parapsilosis y 1 C. tropicalis. RESULTS: MIC50 and MIC90 for FLZ against C...
June 2016: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/26991298/susceptibility-and-molecular-characterization-of-candida-species-from-patients-with-vulvovaginitis
#17
Gheniffer Fornari, Vania Aparecida Vicente, Renata Rodrigues Gomes, Marisol Dominguez Muro, Rosangela Lameira Pinheiro, Carolina Ferrari, Patricia Fernanda Herkert, Marcos Takimura, Newton Sérgio de Carvalho, Flavio Queiroz-Telles
Vulvovaginal candidiasis affects women of reproductive age, which represents approximately 15-25% of vaginitis cases. The present study aimed to isolate and characterize yeast from the patients irrespective of the presentation of clinical symptoms. The isolates were subjected to in vitro susceptibility profile and characterization by molecular markers, which intended to assess the distribution of species. A total of 40 isolates were obtained and identified through the CHROMagar, API20aux and by ITS and D1/D2 regions sequencing of DNAr gene...
April 2016: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/26942354/alterations-in-the-genital-microbiota-in-women-with-spinal-cord-injury
#18
Cristhiane V G Pires, Iara M Linhares, Felipe Serzedello, Eiko I Fukazawa, Edmund C Baracat, Steven S Witkin
OBJECTIVE: To evaluate the vaginal and cervical microbiota in women with spinal cord injury compared with mobile women. METHODS: Fifty-two women with spinal cord injury (study group) and 57 mobile women (control group) were evaluated in a case-control study. All answered a structured questionnaire and were submitted to the following microbiological tests: microscopic examination of vaginal secretions for Trichomonas vaginalis and yeasts, Nugent score by Gram stain, bacterial culture, yeast culture, and endocervical sampling for Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma species...
February 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/26931504/a-prospective-observational-study-of-vulvovagintis-in-pregnant-women-in-argentina-with-special-reference-to-candidiasis
#19
María J Mucci, María L Cuestas, María M Cervetto, María F Landaburu, María T Mujica
To evaluate the frequency of yeast, bacteria or protozoa in pregnant women and to correlate the possible associations of these microorganisms and their relationships with vulvovaginitis (VV) and cervicitis. Vaginal specimens were collected and prepared for smears in microscope slides for the evaluation of yeast, Trichomonas vaginalis and bacteria. Samples were cultured in specific culture medium. Cervical specimens were used to investigate the presence of Neisseria gonorrhoeae, Chlamydia trachomatis, Ureaplasma spp...
July 2016: Mycoses
https://www.readbyqxmd.com/read/26927371/-pulsatilla-decoction-inhibits-vulvovaginal-candida-albicans-proliferation-and-reduces-inflammatory-cytokine-levels-in-vulvovaginal-candidiasis-mice
#20
Dan Xia, Mengxiang Zhang, Gaoxiang Shi, Zhiqing Xu, Daqiang Wu, Jing Shao, Tianming Wang, Changzhong Wang
OBJECTIVE: To explore the possible regulatory effect of Pulsatilla decoction on Th17 cells and inflammatory cytokines of vulvovaginal candidiasis (VVC) mice. METHODS: Seventy-two female Kunming mice were randomly assigned into six groups: a blank control group, a VVC model group, a fluconazole group and three Pulsatilla decoction groups (dose levels: 22.5, 15.0 and 7.5 g/kg, respectively). The VVC mouse models were established by vaginal inoculation with Candida albicans (C...
February 2016: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
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