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Guan-Kai Zhao, Wei Lin, Hong-Jie Chen, Yao-Kun Lv, Xiao-Mei Tan, Zhong-Min Yang, Valery M Mashinsky, Alexander Krylov, Ai-Ping Luo, Hu Cui, Zhi-Chao Luo, Wen-Cheng Xu, Evgeny M Dianov
We experimentally demonstrate the generation of dissipative soliton resonance (DSR) in a passively mode-locked Bi-doped fiber ring laser based on nonlinear polarization rotation (NPR) technique. The DSR with the central wavelength of 1169.5 nm has a repetition rate of 343.7 kHz. By purely increasing the pump power, the DSR evolves from Gaussian shape to rectangular shape with the duration extending from 2.1 ns to 13.1 ns, while keeping the pulse amplitude and the 3-dB spectrum bandwidth almost constant. The single-pulse energy reaches 24...
August 21, 2017: Optics Express
Dorothée S Ziegler, Robert Greiner, Henning Lumpe, Laura Kqiku, Konstantin Karaghiosoff, Paul Knochel
A regioselective zincation of the 2-pyridone and 2,7-naphthyridone scaffolds has been developed. Zincations of the methoxyethoxymethyl (MEM)-protected compounds using TMP2Zn·2MgCl2·2LiCl (TMP = 2,2,6,6-tetramethylpiperidyl) followed by trapping with electrophiles provided functionalized 2-pyridones and 2,7-naphthyridones. I/Mg exchange of iodinated 2-pyridone and 2,7-naphthyridone using i-PrMgCl·LiCl afforded magnesiated intermediates that reacted with electrophiles. A second magnesiation of the 2-pyridone scaffold was achieved by using TMPMgCl·LiCl...
October 17, 2017: Organic Letters
Derya Aydin Sarikurt, Cagri Gokdemir, Nadim K Copty
The rate of interphase mass transfer from non-aqueous phase liquids (NAPLs) entrapped in the subsurface into the surrounding mobile aqueous phase is commonly expressed in terms of Sherwood (Sh) correlations that are expressed as a function of flow and porous media properties. Because of the lack of precise methods for the estimation of the interfacial area separating the NAPL and aqueous phases, most studies have opted to use modified Sherwood expressions that lump the interfacial area into the interphase mass transfer coefficient...
October 4, 2017: Journal of Contaminant Hydrology
Jane Peiwen Lim, Jack Kian Ch'ng, Choon Chieh Tan
Undifferentiated pleomorphic sarcoma very rarely affect the neck. We report a case of a 62year old man who presented with a right sided skin lump which he noticed after sustaining a neck contusion in a road traffic accident about one year ago. The initial CT and ultrasound scans of the lump were suggestive of a thrombosed varix. Clinical examination showed a hard skin nodule with signs of tethering. He underwent a wide excision of the skin nodule and the histology showed undifferentiated pleomorphic sarcoma with margins involved...
October 9, 2017: International Journal of Surgery Case Reports
Chao Shi, Zongcheng Liu, Xinmin Dong, Yong Chen
A novel tracking error-compensation-based adaptive neural control scheme is proposed for a class of high-order nonlinear systems with completely unknown nonlinearities and input delay. In the tracking errors of existing papers, there exist the following difficulties: first, output curve always lags behind the desired trajectory, second, some big peak errors cause a decrease in tracking precision, and third, a big initial value of the modified tracking error can make the closed-loop system unstable. To tackle them, three corresponding error-compensation terms are constructed, including a prediction and compensation term, an auxiliary signal produced by the constructed auxiliary system, and a damping term...
October 10, 2017: IEEE Transactions on Neural Networks and Learning Systems
Fouzia Siraj, Manveen Kaur, Varsha Dalal, Jain Sonam
BACKGROUND: Inflammatory myofibroblastic tumor (IMT) is a rare, distinctive lesion composed of a proliferation of myofibroblastic spindle cells accompanied by an inflammatory infiltrate. It was first described in the lung, but its occurrence at various extrapulmonary sites has also been reported. The literature mentions only a handful of cases of IMT in the breast and only 1 case in the male breast. We report the second case of IMT in the male breast. CASE REPORT: A 60-year-old male presented with a large, lobulated lump in the left breast that had progressively increased in size during the past year...
2017: Ochsner Journal
Gábor Cserni
Solitary breast metastases are rare and mimic primary breast carcinoma. A 60-year-old female with a history of pulmonary adenocarcinoma presented with a solitary left breast lump suspicious for malignancy on breast imaging. Core-needle biopsy disclosed an adenocarcinoma strongly and diffusely positive for oestrogen receptors. Further immunohistochemistry was consistent with the breast tumour being a solitary metastasis of her pulmonary cancer. Clinicians and pathologists should be aware of the fact that pulmonary adenocarcinomas may sometimes display strong rather than only focal positivity for oestrogen receptors by immunohistochemistry and may mimic breast cancer of no special type...
2017: Polish Journal of Pathology: Official Journal of the Polish Society of Pathologists
Francesco Scardulla, Diego Bellavia, Patrizio Vitulo, Giuseppe Romano, Chiara Mina, Giovanni Gentile, Francesco Clemenza, Salvatore Pasta
Pulmonary hypertension (PH) is a disease characterized by progressive adverse remodeling of the distal pulmonary arteries, resulting in elevated pulmonary vascular resistance and load pressure on the right ventricle (RV), ultimately leading to RV failure. Invasive hemodynamic testing is the gold standard for diagnosing PH and guiding patient therapy. We hypothesized that lumped-parameter and biventricular finite-element (FE) modeling may lead to noninvasive predictions of both PH-related hemodynamic and biomechanical parameters that induce PH...
October 18, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Andre S Litwin, Cornelia Poitelea, Petrina Tan, Kimia Ziahosseini, Raman Malhotra
PURPOSE: To report the complications of grafting of excised posterior orbital fat into the lower lid-cheek junction at the time of orbital decompression surgery. METHODS: Retrospective review of consecutive patients undergoing orbital decompression combined with grafting of posterior orbital fat to the pre-malar and lateral canthal area (FG). A second group of consecutive patients undergoing orbital decompression but no orbital fat grafting (NoFG) were also studied as a form of comparative control...
October 12, 2017: Orbit
Tom Stonier, Nick Simson, Ben Challacombe
Although the incidence of testicular cancer has increased over the past few decades, testicular tumours are still rare and many GPs will only see one or two new diagnoses in their career. In one UK study, out of 845 patients who had been referred with testicular lumps or pain, only 33 (4%) were diagnosed with testicular cancer. Epididymal cysts, or spermatoceles when containing sperm, were the most common finding, and were found in 228 patients (27%). The second most common finding was hydrocele, a fluid collection between the parietal and visceral layers of the tunica vaginalis, which was found in 96 patients (11%)...
April 2017: Practitioner
Ankit Mangla, Nikki Agarwal, Michael Russell Mullane
BACKGROUND: The totally implantable venous access port plays a crucial role in delivering chemotherapy in the outpatient setting. Here, we report the first case of a patient with hypopharyngeal tumor who developed chest wall metastasis over the totally implantable venous access port inserted in the internal jugular vein. METHODS: Our patient, a 58-year-old man with a hypopharyngeal tumor presented with a lump over the totally implantable venous access port site...
October 9, 2017: Head & Neck
A S McQueen, K S Bhatia
High-resolution ultrasound (US) provides superb anatomical detail in the superficial anatomy of the neck and has become the first-line imaging investigation for neck lumps and a crucial component of clinical pathways. In this article, a wide range of advances in neck US are described with a focus on the emerging role of ultrasound elastography. Selected examples of clinical utility are presented across a spectrum of scenarios with discussion of newer applications, service delivery, and training issues. The changing role of the neck ultrasound practitioner and the future of the technique in the head and neck are considered...
October 3, 2017: Clinical Radiology
Haisong Yang, Ling Li, Mengmeng Zhang, Shiyong Zhang, Shu Xu, Xiaoxia Ma
RATIONALE: Although rare, occult breast cancer (OBC) originates from breast tissue. Its primary lesions cannot be identified by clinical examination or imaging; therefore, the diagnosis, treatment, and prognosis remain controversial. PATIENT CONCERNS: This study comprised 5 female OBC patients who were admitted to the Affiliated Hospital of Guizhou Medical University for painless axillary lumps. DIAGNOSES: F-flurodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) indicated metastasis in the ipsilateral axillary lymph nodes...
October 2017: Medicine (Baltimore)
Yoav Amitai, Orit Golan, Yoav Barnea, Joseph Klausner, Tehillah S Menes
BACKGROUND: Oncoplastic reconstruction is increasingly used in the management of women undergoing breast conserving surgery. We examined the findings on breast exam and imaging of patients who underwent breast conservation with or without oncoplastic reconstruction. OBJECTIVE: We hypothesized that patients undergoing immediate breast reconstruction would present with more palpable and imaging abnormalities compared to lumpectomy alone and undergo therefore more biopsies...
October 3, 2017: Breast Disease
Michael Thomas, Aadil Mumith, Yaser Ghani
A 24-year-old woman escaped a fire by jumping from the first floor of her house onto a temporary greenhouse. She was brought into the emergency department and later treated surgically. Three years after the initial episode a tender lump in her right thigh was found during regular follow-up for her acute myeloid leukaemia, for which she was in remission. This was treated as a suspicious mass due to her haematological history and further imaging was organised. This was later identified as a piece of the greenhouse that she had landed on 7 years previously...
October 4, 2017: BMJ Case Reports
P S Aravinda, Hirdaya Hulas Nag, Vithal Kumar M Betigeri, Puja Sakhuja, Ashok Sharma
Arterio-Venous Malformations (AVMs) are high flow vascular anomalies, commonly seen in head, neck and extremities. AVMs represent a direct connection between the arterial and the venous systems. They are congenital, often asymptomatic and rarely manifest before adolescence. Depending on the site, size and symptoms, treatment options varies from conservative management to surgical resection. Here, we report a case of 20-year-old male patient with long standing lump in the anterior abdominal wall with no typical clinical features of vascular lesions...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
Goutam Bera, Zeenat Ara, Moumita Sengupta, Uttara Chatterjee, Madhumita Mukhopadhyay
Wilms' tumour, a renal malignancy, primarily occurs in children with a peak incidence between 2 to 5 years age group and accounts for approximately 95% of childhood renal malignancies. Though rarely, it may also occur in adults with an incidence rate of less than 0.2 per million per year. Microscopically, there is no difference between Wilms' tumour of paediatric and adult age groups. But the prognosis for adults with Wilms' tumour is thought to be worse than that for children possibly due to more aggressive clinical course in case of adult Wilms' tumour...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
Prasath Sathiah, Debasis Gochhait, Subathra Adithan, Sandhya Umamahesweran, Priyadarshini Dehuri
Amelanotic signet ring cell melanoma is one of the rare variants of malignant melanoma. Here we are presenting a case of a 58-year-old female with chief complaints of swelling in the left sternal region/breast, and right cervical region. Contrast Enhanced CT scan showed the two well circumscribed lobular mass lesions with central necrosis in the left breast. The radiologist opined the lesions as intramammary nodes. Biopsy from the larger breast mass lesion showed a tumour with cells arranged in discohesive pattern less with hetrogenos morphology...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
Jiangtao Li, Zheng Zhao, Longjie Li, Jiaxin He, Chenjie Li, Yifeng Wang, Can Su
A transmission line transformer has potential advantages for nanosecond pulse generation including excellent frequency response and no leakage inductance. The wave propagation process in a secondary mode line is indispensable due to an obvious inside transient electromagnetic transition in this scenario. The equivalent model of the transmission line transformer is crucial for predicting the output waveform and evaluating the effects of magnetic cores on output performance. However, traditional lumped parameter models are not sufficient for nanosecond pulse generation due to the natural neglect of wave propagations in secondary mode lines based on a lumped parameter assumption...
September 2017: Review of Scientific Instruments
Benjamin Elie, Yves Laprie
The paper presents a numerical study about the acoustic impact of the gradual glottal opening on the production of fricatives. Sustained fricatives are simulated by using classic lumped circuit element methods to compute the propagation of the acoustic wave along the vocal tract. A recent glottis model is connected to the wave solver to simulate a partial abduction of the vocal folds during their self-oscillating cycles. Area functions of fricatives at the three places of articulation of French have been extracted from static MRI acquisitions...
September 2017: Journal of the Acoustical Society of America
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