keyword
https://read.qxmd.com/read/38490482/matrix-confinement-modulates-3d-spheroid-sorting-and-burst-like-collective-migration
#1
JOURNAL ARTICLE
Grace Cai, Xinzhi Li, Shan- Shan Lin, Samuel J Chen, Nicole C Rodgers, Katherine M Koning, Dapeng Bi, Allen P Liu
While it is known that cells with differential adhesion tend to segregate and preferentially sort, the physical forces governing sorting and invasion in heterogeneous tumors remain poorly understood. To investigate this, we tune matrix confinement, mimicking changes in the stiffness and confinement of the tumor microenvironment, to explore how physical confinement influences individual and collective cell migration in 3D spheroids. High levels of confinement lead to cell sorting while reducing matrix confinement triggers the collective fluidization of cell motion...
March 13, 2024: Acta Biomaterialia
https://read.qxmd.com/read/38489267/relapse-to-cocaine-seeking-is-regulated-by-medial-habenula-nr4a2-nurr1-in-mice
#2
JOURNAL ARTICLE
Jessica E Childs, Samuel Morabito, Sudeshna Das, Caterina Santelli, Victoria Pham, Kelly Kusche, Vanessa Alizo Vera, Fairlie Reese, Rianne R Campbell, Dina P Matheos, Vivek Swarup, Marcelo A Wood
Drugs of abuse can persistently change the reward circuit in ways that contribute to relapse behavior, partly via mechanisms that regulate chromatin structure and function. Nuclear orphan receptor subfamily4 groupA member2 (NR4A2, also known as NURR1) is an important effector of histone deacetylase 3 (HDAC3)-dependent mechanisms in persistent memory processes and is highly expressed in the medial habenula (MHb), a region that regulates nicotine-associated behaviors. Here, expressing the Nr4a2 dominant negative (Nurr2c) in the MHb blocks reinstatement of cocaine seeking in mice...
March 13, 2024: Cell Reports
https://read.qxmd.com/read/38489105/self-regulation-and-academic-learning-in-preschoolers-with-autism-spectrum-disorder-links-to-school-engagement-and-levels-of-autism-characteristics
#3
JOURNAL ARTICLE
Yanru Chen, Laudan B Jahromi
Children with autism spectrum disorder often demonstrate self-regulation challenges and academic difficulties. Although self-regulation has been well documented as an important factor for academic achievement in neurotypical children, little is known about how it is related to academic learning in autistic children, especially during preschool, a critical developmental period for both emergent academic skills and self-regulatory abilities. It is also unclear whether school engagement or autism characteristics influence the relation between self-regulation and academic learning in autistic children during preschool...
March 15, 2024: Journal of Autism and Developmental Disorders
https://read.qxmd.com/read/38488450/neural-signatures-of-shared-subjective-affective-engagement-and-disengagement-during-movie-viewing
#4
JOURNAL ARTICLE
Melanni Nanni-Zepeda, Joseph DeGutis, Charley Wu, David Rothlein, Yan Fan, Simone Grimm, Martin Walter, Michael Esterman, Agnieszka Zuberer
When watching a negative emotional movie, we differ from person to person in the ease with which we engage and the difficulty with which we disengage throughout a temporally evolving narrative. We investigated neural responses of emotional processing, by considering inter-individual synchronization in subjective emotional engagement and disengagement. The neural underpinnings of these shared responses are ideally studied in naturalistic scenarios like movie viewing, wherein individuals emotionally engage and disengage at their own time and pace throughout the course of a narrative...
March 2024: Human Brain Mapping
https://read.qxmd.com/read/38488399/the-impact-of-trauma-sensitive-yoga-on-persons-who-are-incarcerated-identifying-understanding-and-controlling-emotions
#5
JOURNAL ARTICLE
Kimberly Collica-Cox, George J Day, Alicia Bennett, Cameron Maruszewski
BACKGROUND: While persons who are incarcerated have high rates of previous trauma, further traumatization can result from the experience of incarceration. The inability to effectively process trauma can lead to maladaptive behavior, a serious concern for correctional administrators. Acquiring the skills to regulate emotions and mitigate feelings of impulsivity help persons who are incarcerated take responsibility for their actions to make better decisions, simultaneously encouraging prosocial behavior, decreasing institutional misconduct, and reducing behaviors that place one at risk for repeated involvement in the criminal justice system...
March 13, 2024: Journal of Forensic Nursing
https://read.qxmd.com/read/38487230/-2-2-cycloaddition-and-its-photomechanical-effects-on-1d-coordination-polymers-with-reversible-amide-bonds-and-coordination-site-regulation
#6
JOURNAL ARTICLE
Lei Wang, Si-Bo Qiao, Yan-Ting Chen, Xun Ma, Wei-Ming Wei, Jun Zhang, Lin Du, Qi-Hua Zhao
Photo-responsive materials can convert light energy into mechanical energy, with great application potential in biomedicine, flexible electronic devices, and bionic systems. We combined reversible amide bonds, coordination site regulation, and coordination polymer (CP) self-assembly to synthesize two 1D photo-responsive CPs. Obvious photomechanical behavior was observed under UV irradiation. By combining the CPs with PVA, the mechanical stresses were amplified and macroscopic driving behavior was realized. In addition, two cyclobutane amide derivatives and a pair of cyclobutane carboxyl isomers were isolated through coordination bond destruction and amide bond hydrolysis...
March 13, 2024: Chemical Science
https://read.qxmd.com/read/38487193/patients-response-during-the-co-circulation-of-multiple-respiratory-diseases-in-china-based-on-the-self-regulation-common-sense-model
#7
JOURNAL ARTICLE
Shanwen Sun, Yali Wang, Hailong Hou, Yuqi Niu, Yefan Shao, Linlin Chen, Xiaochun Zhang
BACKGROUND: Following the COVID-19 pandemic, another large-scale respiratory epidemic has emerged in China, causing significant social impact and disruption. The article is to explore the patients' psychological and behavioral responses to the enhancement of healthcare quality. METHODS: Based on the five dimensions of the Self-Regulation Common-Sense Model, we developed an interview outline to explore the process by which patients identify disease symptoms to guide action plans and coping strategies...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38486949/self-regulatory-control-processes-in-youths-a-temporal-network-analysis-approach
#8
JOURNAL ARTICLE
Fiorella Turri, Andrew Jones, Lauriane Constanty, Setareh Ranjbar, Konstantin Drexl, Giorgia Miano, Caroline Lepage, Kerstin Jessica Plessen, Sébastien Urben
OBJECTIVE: This study aimed to better understand the temporal interrelationships among self-control, response inhibition, and anger (i.e., momentary state and rumination) on both the within- and between-person levels in male adolescents. METHOD: We applied temporal network analyses among 62 male adolescents with a wide range of behavioral difficulties. Self-control, momentary anger, and anger rumination were mapped by self-report measures, whereas we measured response inhibition through an ambulatory Go/No-go task (two measures a day-morning and afternoon-over a 9-day period)...
March 2024: JCPP Adv
https://read.qxmd.com/read/38485625/the-selfish-network-how-the-brain-preserves-behavioral-function-through-shifts-in-neuronal-network-state
#9
REVIEW
Albrecht Stroh, Susann Schweiger, Jan-Marino Ramirez, Oliver Tüscher
Neuronal networks possess the ability to regulate their activity states in response to disruptions. How and when neuronal networks turn from physiological into pathological states, leading to the manifestation of neuropsychiatric disorders, remains largely unknown. Here, we propose that neuronal networks intrinsically maintain network stability even at the cost of neuronal loss. Despite the new stable state being potentially maladaptive, neural networks may not reverse back to states associated with better long-term outcomes...
March 13, 2024: Trends in Neurosciences
https://read.qxmd.com/read/38482742/programming-of-supercrystals-using-replicable-dna-functionalized-colloids
#10
JOURNAL ARTICLE
Xiaoyun Sun, Wenqiang Hua, Xiaoyu Liu, Jing Jin, Jianing Zhang, Jie Tian, Bin Zheng, Wei Jiang, Dongbao Yao, Haojun Liang
The development of self-replicating systems is of great importance in research on the origin of life. As the most iconic molecules, nucleic acids have provided prominent examples of the fabrication of self-replicating artificial nanostructures. However, it is still challenging to construct sophisticated synthetic systems that can create large-scale or three-dimensionally ordered nanomaterials using self-replicating nanostructures. By integrating a template system containing DNA-functionalized colloidal seeds with a simplified DNA strand-displacement circuit programmed subsystem to produce DNA-functionalized colloidal copies, we developed a facile enthalpy-mediated strategy to control the replication and catalytic assembly of DNA-functionalized colloids in a time-dependent manner...
March 14, 2024: Angewandte Chemie
https://read.qxmd.com/read/38478077/gestational-diabetes-perception-profiles-based-on-attachment-style-a-cross-sectional-study
#11
JOURNAL ARTICLE
Ana Munda, Katarina Lia Kompan Erzar, Helena Peric, Draženka Pongrac Barlovič
AIMS: Gestational diabetes (GDM) is a prevalent complication in pregnancy that requires effective self-management, which can be influenced by illness perceptions. Moreover, behavioral regulation can be affected by attachment styles. Thus, our study aimed to identify common GDM perception profiles and test their association with attachment styles. METHODS: In this cross-sectional study, 446 women completed the Relationship Questionnaire (RQ), the Brief Illness Perception Questionnaire (BIPQ), and additional items about GDM diagnosis, information, competence, adherence, behavioral change...
March 13, 2024: Acta Diabetologica
https://read.qxmd.com/read/38477680/the-breakfast-and-dressing-conflict-task-preliminary-evidence-of-its-validity-to-measure-online-self-awareness-after-acquired-brain-injury
#12
JOURNAL ARTICLE
Giorgia Ricchetti, Alba Navarro-Egido, María Rodríguez-Bailón, Daniel Salazar-Frías, Jose Antonio Merchán-Baeza, María Patrocinio Ariza-Vega, María J Funes
IMPORTANCE: Impaired self-awareness (SA) of deficits after an acquired brain injury (ABI) severely affects patients' independence in activities of daily living (ADLs). However, any assessment tool permits an exhaustive evaluation of SA in the context of ADLs. OBJECTIVE: To study the validity of the Breakfast and Dressing Conflict Task (BD Conflict Task) to assess online SA (awareness of performance in the context of a given task) in patients with ABI; to study its interactions with offline SA (general awareness); and to test the validity of a simplified measure of performance monitoring, the ADL Conflict-Monitoring Index...
March 1, 2024: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
https://read.qxmd.com/read/38476350/unveiling-the-impact-of-metacognition-on-academic-achievement-in-physical-education-and-activity-settings-a-comprehensive-systematic-review-and-meta-analysis-of-qualitative-insights
#13
REVIEW
Lixia Bao, Kim Geok Soh, Nasnoor Juzaily Mohd Nasiruddin, Huijuan Xie, Junlong Zhang
PURPOSE: The purpose of this study is to unveil the impact of metacognition on academic achievement in physical education and activity settings by conducting a comprehensive systematic literature review with a meta-analysis of qualitative findings. PATIENTS AND METHODS: Systematic searches identified English-language, peer-reviewed journal articles reporting the results of qualitative or mixed-methods studies of the emerging themes of metacognition on academic achievement in sports...
2024: Psychology Research and Behavior Management
https://read.qxmd.com/read/38473695/electrical-and-electro-thermal-characteristics-of-carbon-black-graphite-lldpe-composites-with-ptc-effect
#14
JOURNAL ARTICLE
Eduard-Marius Lungulescu, Cristina Stancu, Radu Setnescu, Petru V Notingher, Teodor-Adrian Badea
Electrical properties and electro-thermal behavior were studied in composites with carbon black (CB) or hybrid filler (CB and graphite) and a matrix of linear low-density polyethylene (LLDPE). LLDPE, a (co)polymer with low crystallinity but with high structural regularity, was less studied for Positive Temperature Coefficient (PTC) applications, but it would be of interest due to its higher flexibility as compared to HDPE. Structural characterization by scanning electron microscopy (SEM) confirmed a segregated structure resulted from preparation by solid state powder mixing followed by hot molding...
March 6, 2024: Materials
https://read.qxmd.com/read/38470635/mediating-effect-of-self-control-on-the-relationship-between-obesity-related-stress-and-weight-control-behavior-among-female-college-students-with-overweight-and-obesity
#15
JOURNAL ARTICLE
Young-Hee Park, Yeo-Won Jeong, Hyun-Kyeong Park, Seul-Gi Park, Ha-Yeon Kim
BACKGROUND: This study aimed to determine whether self-regulation acts as a mediating factor in the relationship between obesity-related stress and weight control behavior, targeting Korean female college students. Obesity-related stress and weight control behaviors are important factors affecting an individual's health and well-being, and self-control, a psychological trait, can play a pivotal role in regulating how individuals respond to stress and engage in weight management behaviors...
February 22, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38470109/symmetry-of-pyridine-derivatives-controlled-two-dimensional-nanostructural-diversity-by-co-assembly-with-aromatic-carboxylic-acids
#16
JOURNAL ARTICLE
Yutuo Zheng, Songyao Zhang, Xiaoyang Zhao, Xinrui Miao, Wenli Deng
The self-assembly behaviors of aromatic carboxylic acids are commonly investigated at the liquid/solid interfaces because of their rigid skeletons and both hydrogen-bond donors and receptors. However, self-assemblies of aromatic carboxylic acids with low symmetry and interactions between carboxylic acid and pyridine derivatives are worth exploring. In this work, the self-assembled structural transitions of a kind of low-symmetric aromatic carboxylic acid (H4 QDA) are regulated by the coadsorption of two pyridine derivatives (DPE and T4PT) with different symmetry, which are investigated by scanning tunneling microscopy under ambient conditions...
March 12, 2024: Langmuir: the ACS Journal of Surfaces and Colloids
https://read.qxmd.com/read/38469220/effects-of-chronic-home-radon-exposure-on-cognitive-behavioral-and-mental-health-in-developing-children-and-adolescents
#17
JOURNAL ARTICLE
Brittany K Taylor, Haley Pulliam, OgheneTejiri V Smith, Danielle L Rice, Hallie J Johnson, Anna T Coutant, Ryan Glesinger, Tony W Wilson
INTRODUCTION: It is well-established that chronic exposure to environmental toxins can have adverse effects on neuropsychological health, particularly in developing youths. However, home radon, a ubiquitous radiotoxin, has been seldom studied in this context. In the present study, we investigated the degree to which chronic everyday home radon exposure was associated with alterations in transdiagnostic mental health outcomes. METHODS: A total of 59 children and adolescents ages 6- to 14-years-old ( M  = 10...
2024: Frontiers in Psychology
https://read.qxmd.com/read/38469207/the-impact-of-recent-life-events-internalizing-symptoms-and-emotion-regulation-on-the-severity-of-non-suicidal-self-injury-in-adolescents-a-mediation-analysis
#18
JOURNAL ARTICLE
Linqi Zhou, Changyuan Qiao, Jialing Huang, Jian Lin, Haisheng Zhang, Jian Xie, Yonggui Yuan, Changchun Hu
BACKGROUND: Previous studies have demonstrated a strong association between recent stressful life events and non-suicidal self-injury (NSSI) among adolescents. Internalizing symptoms and difficulty in emotion regulation (DER) may mediate this relationship. This study aimed to investigate the relationship between recent stressful life events and NSSI severity in adolescents and the potential moderating role of internalizing symptoms and DER. METHODS: A total of 224 adolescent inpatients (78...
2024: Neuropsychiatric Disease and Treatment
https://read.qxmd.com/read/38466606/physics-informed-deep-learning-for-muscle-force-prediction-with-unlabeled-semg-signals
#19
JOURNAL ARTICLE
Shuhao Ma, Jie Zhang, Chaoyang Shi, Pei Di, Ian D Robertson, Zhi-Qiang Zhang
Computational biomechanical analysis plays a pivotal role in understanding and improving human movements and physical functions. Although physics-based modeling methods can interpret the dynamic interaction between the neural drive to muscle dynamics and joint kinematics, they suffer from high computational latency. In recent years, data-driven methods have emerged as a promising alternative due to their fast execution speed, but label information is still required during training, which is not easy to acquire in practice...
March 11, 2024: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://read.qxmd.com/read/38466341/forkhead-box-o-proteins-steering-the-course-of-stem-cell-fate
#20
REVIEW
Mengdi Cheng, Yujie Nie, Min Song, Fulin Chen, Yuan Yu
Stem cells are pivotal players in the intricate dance of embryonic development, tissue maintenance, and regeneration. Their behavior is delicately balanced between maintaining their pluripotency and differentiating as needed. Disruptions in this balance can lead to a spectrum of diseases, underscoring the importance of unraveling the complex molecular mechanisms that govern stem cell fate. Forkhead box O (FOXO) proteins, a family of transcription factors, are at the heart of this intricate regulation, influencing a myriad of cellular processes such as survival, metabolism, and DNA repair...
March 11, 2024: Cell Regeneration
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