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https://www.readbyqxmd.com/read/28810348/-a-preliminary-discussion-on-the-contents-and-value-of-all-diseases-1-the-medical-bamboo-slips-unearthed-from-han-tomb-in-laoguanshan-of-chengdu
#1
Y Ye, Q Zhang, Y L Ren, J M Li
Among the medical bamboo slips unearthed from Han tomb in Laoguanshan of Chengdu, the Zhu bing (All Diseases) is a monograph to discuss the characteristics of signs and symptoms. Based on the differences of writing styles, diseases involved, expounding methods and writing rules, the book is divided, by the research team, into 2 parts: All Diseases(1) and All Diseases(2). All Diseases(1) includes over 130 slips, 2 000 characters with totally more than 100 disease names, containing multiple clinical disciplines...
May 28, 2017: Zhonghua Yi Shi za Zhi, Chinese Journal of Medical History
https://www.readbyqxmd.com/read/28810152/driving-forces-and-impacts-of-food-system-nitrogen-flows-in-china-1990-to-2012
#2
Bing Gao, Yunfeng Huang, Wei Huang, Yalan Shi, Xuemei Bai, Shenghui Cui
Food nitrogen (N), which includes animal-food (AN) and plant-food N (PN), has been driven by population growth (PG), dietary changes associated with income growth (DC) and rural-urban migration (M) over the past three decades, and these changes combined with their N cost, have caused some effect on N use in China's food system. Although there is an increasing literature on food N and its environmental impacts in China, the relative magnitude of these driving forces are not well understood. Here we first quantify the differences in per capita AN and PN consumption in urban and rural areas and their impacts on N input to the food system during 1990-2012, and then quantify the relative contributions of DC, PG and M in the overall N change during this period...
August 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28804985/a-randomised-controlled-comparison-of-second-level-treatment-approaches-for-treatment-resistant-adults-with-bulimia-nervosa-and-binge-eating-disorder-assessing-the-benefits-of-virtual-reality-cue-exposure-therapy
#3
Marta Ferrer-García, José Gutiérrez-Maldonado, Joana Pla-Sanjuanelo, Ferran Vilalta-Abella, Giuseppe Riva, Massimo Clerici, Joan Ribas-Sabaté, Alexis Andreu-Gracia, Fernando Fernandez-Aranda, Laura Forcano, Nadine Riesco, Isabel Sánchez, Neli Escandón-Nagel, Osane Gomez-Tricio, Virginia Tena, Antonios Dakanalis
A question that arises from the literature on therapy is whether second-level treatment is effective for patients with recurrent binge eating who fail first-level treatment. It has been shown that subjects who do not stop binge eating after an initial structured cognitive-behavioural treatment (CBT) programme benefit from additional CBT (A-CBT) sessions; however, it has been suggested that these resistant patients would benefit even more from cue exposure therapy (CET) targeting features associated with poor response (e...
August 14, 2017: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/28803118/complex-interactions-between-the-subject-factors-of-biological-sex-and-prior-histories-of-binge-drinking-and-unpredictable-stress-influence-behavioral-sensitivity-to-alcohol-and-alcohol-intake
#4
Sema G Quadir, Eugenie Guzelian, Mason A Palmer, Douglas L Martin, Jennifer Kim, Karen K Szumlinski
Alcohol use disorders, affective disorders and their comorbidity are sexually dimorphic in humans. However, it is difficult to disentangle the interactions between subject factors influencing alcohol sensitivity in studies of humans. Herein, we combined murine models of unpredictable, chronic, mild stress (UCMS) and voluntary binge-drinking to examine for sex differences in the interactions between prior histories of excessive ethanol-drinking and stress upon ethanol-induced changes in motor behavior and subsequent drinking...
August 9, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28797427/low-level-tragus-stimulation-for-the-treatment-of-ischemia-and-reperfusion-injury-in-patients-with-st-segment-elevation-myocardial-infarction-a-proof-of-concept-study
#5
Lilei Yu, Bing Huang, Sunny S Po, Tuantuan Tan, Menglong Wang, Liping Zhou, Guannan Meng, Shenxu Yuan, Xiaoya Zhou, Xuefei Li, Zhuo Wang, Songyun Wang, Hong Jiang
OBJECTIVES: The aim of this study was to investigate whether low-level tragus stimulation (LL-TS) treatment could reduce myocardial ischemia-reperfusion injury in patients with ST-segment elevation myocardial infarction (STEMI). BACKGROUND: The authors' previous studies suggested that LL-TS could reduce the size of myocardial injury induced by ischemia. METHODS: Patients who presented with STEMI within 12 h of symptom onset, treated with primary percutaneous coronary intervention, were randomized to the LL-TS group (n = 47) or the control group (with sham stimulation [n = 48])...
August 14, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28796618/learning-based-shadow-recognition-and-removal-from-monochromatic-natural-images
#6
Mingliang Xu, Jiejie Zhu, Pei Lv, Bing Zhou, Marshall F Tappen, Rongrong Ji
This paper addresses the problem of recognizing and removing shadows from monochromatic natural images from a learning based perspective. Without chromatic information, shadow recognition and removal are extremely challenging in the literature, mainly due to the missing of invariant color cues. Natural scenes make this problem even harder due to the complex illumination condition and ambiguity from many near-black objects. In this paper, a learning based shadow recognition and removal scheme is proposed to tackle the challenges above...
August 7, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28796052/association-of-elevated-resting-pulse-rate-with-increased-risk-of-hypertension-development-in-children-a-prospective-study-in-suzhou-china
#7
Jia Hu, Hui Shen, Guang-Ping Chu, Han Fu, Fei-Fei Huang, Yan-Min Zheng, Di Han, Yi-Kai Zhou, Qi Wang, Bo Wang, Chen-Gang Teng, Fang Liu, Hai-Bing Yang
BACKGROUND: Elevated resting heart rate (RHR) or resting pulse rate (RPR) is associated with increased risk of hypertension development. However, information is limited to adults. The purpose of this study is to analyze this association among Chinese children in a prospective design. METHODS: A total of 4861 children who participated in the Blood Pressure Surveillance Program (2011-2017) were selected in this research. To investigate the association between RPR and hypertension development, children were divided into 4 groups according to the quartiles of RPR at baseline...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28792587/electromyographic-bridge-for-promoting-the-recovery-of-hand-movements-in-subacute-stroke-patients-a-randomized-controlled-trial
#8
Yu-Xuan Zhou, Yang Xia, Jia Huang, Hai-Peng Wang, Xue-Liang Bao, Zheng-Yang Bi, Xiao-Bing Chen, Yu-Jie Gao, Xiao-Ying Lü, Zhi-Gong Wang
OBJECTIVE: The electromyographic bridge (EMGB) detects surface electromyographic signals from a non-paretic limb. It then generates electric pulse trains according to the electromyographic time domain features, which can be used to stimulate a paralysed or paretic limb in real time. This strategy can be used for the contralateral control of neuromuscular electrical stimulation (NMES) to improve motor function after stroke. The aim of this study was to compare the treat-ment effects of EMGB vs cyclic NMES on wrist and finger impairments in subacute stroke patients...
August 9, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28792464/histological-and-immunohistochemical-analyses-of-repair-of-the-disc-in-the-rabbit-temporomandibular-joint-using-a-collagen-template
#9
Kuo-Hwa Wang, Wing P Chan, Li-Hsuan Chiu, Yu-Hui Tsai, Chia-Lang Fang, Charn-Bing Yang, Kuan-Chou Chen, Hung-Li Tsai, Wen-Fu Lai
A previous study demonstrated that the reconstituted type I collagen matrix extracted from rabbit tendons enabled the TMJ disc to regenerate in the rabbit. The aim of this study was to investigate changes in the extracellular matrix (ECM) and mechanisms of regeneration in the TMJ disc. In 36 New Zealand rabbits that underwent a partial discectomy, discs were replaced with reconstituted collagen templates for 3 months. A histological analysis showed that moderate to severe degeneration appeared in partially discectomized joints without implantation...
August 9, 2017: Materials
https://www.readbyqxmd.com/read/28783872/evaluation-of-potential-drug-drug-interaction-between-delayed-release-dimethyl-fumarate-and-a-commonly-used-oral-contraceptive-norgestimate-ethinyl-estradiol-in-healthy-women
#10
Bing Zhu, Ivan Nestorov, Guolin Zhao, Venkata Meka, Mark Leahy, Jeanelle Kam, Sarah I Sheikh
Delayed-release dimethyl fumarate (DMF) is an oral therapy for relapsing multiple sclerosis with anti-inflammatory and neuroprotective properties. This 2-period crossover study was conducted to evaluate the potential for drug-drug interaction between DMF (240 mg twice daily) and a combined oral contraceptive (OC; norgestimate 250 μg, ethinyl estradiol 35 μg). Forty-six healthy women were enrolled; 32 completed the study. After the lead-in period (OC alone), 41 eligible participants were randomized 1:1 to sequence 1 (OC and DMF coadministration in period 1; OC alone in period 2) or sequence 2 (regimens reversed)...
August 7, 2017: Clinical Pharmacology in Drug Development
https://www.readbyqxmd.com/read/28782278/highly-selective-artificial-potassium-ion-channels-constructed-from-pore-containing-helical-oligomers
#11
Lang Chao, Xiaoli Deng, Wei Wang, Shuaiwei Qi, Xin Zhang, Chenyang Zhang, Feihu Yang, Bing Yang, Zeyuan Dong, Junqiu Liu
Potassium ion channels specifically transport K+ ions over Na+ ions across the cell membrane. A queue of four binding sites in the K+ channel pore plays significant roles during highly selective conduction. Herein, we synthesized a kind of aromatic helical oligomers that can selectively bind K+ over Na+. By aromatic stacking of helical oligomers, a type of artificial K+ channels with contiguous K+ binding sites was constructed. We discovered that such artificial channels exhibited exceptionally high K+/Na+ selectivity ratios during transmembrane ion conduction...
August 6, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28780081/grb7-is-over-expressed-in-cervical-cancer-and-facilitate-invasion-and-inhibit-apoptosis-in-cervical-cancer-cells
#12
Hong-Bing Zhao, Xi-Feng Zhang, Xue-Lin Jia, Hao-Bin Wang
Growth factor receptor bound protein-7 (Grb7) is a multi-domain adaptor protein that is co-opted by numerous tyrosine kinases involved in various cellular signaling. The objective of this study was to investigate the expression of Grb7 and its clinicopathological significance in cervical cancer. Utilising immunohistochemical staining, we examined the expression of Grb7 in 120 cases of human cervical cancer tissue and 10 cases of adjacent non-cancerous cervical tissue. The positive rate of Grb7 protein expression was 34...
July 26, 2017: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28777427/paclitaxel-oxaliplatin-5-fluorouracil-and-leucovorin-combination-chemotherapy-in-patients-with-recurrent-or-metastatic-gastric-cancer
#13
Yan-Qin Lan, Ri-Ping Wu, Xiao-Bing Huang, Xin-Li Wang, Dong-Ta Zhong, Chuan-Yong Huang, Jin-Tian Song
PURPOSE: This study evaluated the efficacy and toxicity of combination chemotherapy with paclitaxel, oxaliplatin, 5-fluorouracil and leucovorin (POFL) in patients with recurrent or metastatic gastric cancer. METHODS: One hundred and thirty-eight patients with histologically confirmed recurrent or metastatic gastric adenocarcinoma were treated with the POFL regimen: paclitaxel at a dose of 135 mg/m2 as a 3-hour intravenous infusion on day 1, oxaliplatin 85 mg/m2 and leucovorin 400 mg/m2 as an intravenous infusion over 2 hours on day 1, followed by 5-fluorouracil 2,400 mg/m2 as an infusion over a 46-hour period on 3 consecutive days, in a 2-week cycle...
July 27, 2017: Tumori
https://www.readbyqxmd.com/read/28775186/are-thyroid-nodules-associated-with-sex-related-hormones-a-cross-sectional-spect-china-study
#14
Yi Chen, Yingchao Chen, Ningjian Wang, Chi Chen, Xiaomin Nie, Qin Li, Bing Han, Fangzhen Xia, Hualing Zhai, Boren Jiang, Zhoujun Shen, Yingli Lu
OBJECTIVE: Little is known about the association between thyroid nodules (TNs) and endogenous sex hormones. We aimed to investigate the relationship between TNs and sex-related hormones among men in China. SETTING: The data were obtained from a cross-sectional study Survey on Prevalence in East China for Metabolic Diseases and Risk Factors (SPECT-China study, 2014-2015) based on the population. PARTICIPANTS: In total, 4024 men over 18 years of age who were not using hormone replacement therapy and who underwent complete assays of the serum total testosterone (T), oestradiol (E2), follicle-stimulating hormone (FSH), luteinising hormone (LH) and sex hormone-binding globulin (SHBG) levels as well as thyroid ultrasonography (US) enrolled in this study...
August 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28773993/effect-of-glucose-concentration-on-electrochemical-corrosion-behavior-of-pure-titanium-ta2-in-hanks-simulated-body-fluid
#15
Shuyue Liu, Bing Wang, Peirong Zhang
Titanium and its alloys have been widely used as implant materials due to their excellent mechanical property and biocompatibility. In the present study, the effect of glucose concentration on corrosion behavior of pure titanium TA2 in Hanks' simulated body fluid is investigated by the electrochemical impedance spectrum (EIS) and potentiodynamic polarization methods. The range of glucose concentrations investigated in this research includes 5 mmol/L (limosis for healthy people), 7 mmol/L (after diet for healthy people), 10 mmol/L (limosis for hyperglycemia patient), and 12 mmol/L (after diet for hyperglycemia patient), as well as, 15 mmol/L and 20 mmol/L, which represent different body fluid environments...
October 26, 2016: Materials
https://www.readbyqxmd.com/read/28770546/leptin-promotes-the-migration-and-invasion-of-breast-cancer-cells-by-upregulating-acat2
#16
Yunxiu Huang, Qianni Jin, Min Su, Feihu Ji, Nian Wang, Changli Zhong, Yulin Jiang, Yifeng Liu, Zhiqian Zhang, Junhong Yang, Lan Wei, Tingmei Chen, Bing Li
BACKGROUND: Previously, it has been shown that obesity may be considered as a risk factor for breast cancer in postmenopausal women. Leptin, a hormone whose level is elevated in obesity, has been suggested to be involved in the development of breast cancer, and univariate survival analyses have shown that over-expression of ACAT2, an enzyme that is involved in the production of cholesteryl esters, may be associated with a poor prognosis. Here, we aimed to investigate the effect of leptin on the proliferation, migration and invasion of breast cancer cells, as well as to elucidate its underlying mode of action...
August 2, 2017: Cellular Oncology (Dordrecht)
https://www.readbyqxmd.com/read/28768334/effect-of-internet-based-guided-self-help-vs-individual-face-to-face-treatment-on-full-or-subsyndromal-binge-eating-disorder-in-overweight-or-obese-patients-the-interbed-randomized-clinical-trial
#17
Martina de Zwaan, Stephan Herpertz, Stephan Zipfel, Jennifer Svaldi, Hans-Christoph Friederich, Frauke Schmidt, Andreas Mayr, Tony Lam, Carmen Schade-Brittinger, Anja Hilbert
Importance: Although cognitive behavioral therapy (CBT) represents the criterion standard for treatment of binge eating disorder (BED), most individuals do not have access to this specialized treatment. Objective: To evaluate the efficacy of internet-based guided self-help (GSH-I) compared with traditional, individual face-to-face CBT. Design, Setting, and Participants: The Internet and Binge Eating Disorder (INTERBED) study is a prospective, multicenter, randomized, noninferiority clinical trial (treatment duration, 4 months; follow-ups, 6 months and 1...
August 2, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28763640/transformation-and-fate-of-natural-estrogens-and-their-conjugates-in-wastewater-treatment-plants-influence-of-operational-parameters-and-removal-pathways
#18
Weiwei Ben, Bing Zhu, Xiangjuan Yuan, Yu Zhang, Min Yang, Zhimin Qiang
Natural estrogens (NEs) discharged from wastewater treatment plants (WWTPs) have drawn great attention because of their potential risks to aquatic ecosystems. However, neglect of the conjugated natural estrogens (C-NEs) has caused large discrepancies among different studies on the removal of NEs in WWTPs. The present work investigated the transformation and fate of three NEs and six corresponding C-NEs along wastewater treatment processes. The removal efficiencies of the target estrogens (i.e., NEs and C-NEs) and their correlations with the operational parameters were determined over a twelve-month monitoring period at a typical WWTP adopting a combined bio-treatment process (i...
July 26, 2017: Water Research
https://www.readbyqxmd.com/read/28762946/plasticity-of-calcium-permeable-ampa-glutamate-receptors-in-pro-opiomelanocortin-neurons
#19
Shigetomo Suyama, Alexandra Ralevski, Zhong-Wu Liu, Marcelo O Dietrich, Toshihiko Yada, Stephanie E Simonds, Michael A Cowley, Xiao-Bing Gao, Sabrina Diano, Tamas L Horvath
POMC neurons integrate metabolic signals from the periphery. Here, we show in mice that food deprivation induces a linear current-voltage relationship of AMPAR-mediated excitatory postsynaptic currents (EPSCs) in POMC neurons. Inhibition of EPSCs by IEM-1460, an antagonist of calcium-permeable (Cp) AMPARs, diminished EPSC amplitude in the fed but not in the fasted state, suggesting entry of GluR2 subunits into the AMPA receptor complex during food deprivation. Accordingly, removal of extracellular calcium from ACSF decreased the amplitude of mEPSCs in the fed but not the fasted state...
August 1, 2017: ELife
https://www.readbyqxmd.com/read/28757566/health-inequities-among-lesbian-gay-and-bisexual-adults-in-north-carolina-2011-2014
#20
Melissa M Barnhill, Joseph G L Lee, Ann P Rafferty
Inequalities in health have been identified for lesbian, gay, and bisexual (LGB) populations nationally. Policies in the U.S. South offer fewer protections for LGB people than in other regions, yet, limited data exist for this region. North Carolina (NC) BRFSS data from 2011 to 2014 were combined (LGB n = 604; heterosexual n = 33,170) and analyzed using SAS survey procedures to estimate health characteristics by sexual orientation within gender. Many examined indicators were not different by sexual orientation, however, other results were significant and consistent with findings from state population surveys in other regions of the country...
July 25, 2017: International Journal of Environmental Research and Public Health
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