keyword
MENU ▼
Read by QxMD icon Read
search

paraneoplasic syndrome

keyword
https://www.readbyqxmd.com/read/27602070/high-dose-rate-intraluminal-brachytherapy-for-paraneoplastic-autoimmune-multiorgan-syndrome
#1
Sun-Young Lee, Jong-Hyun Kim, Dong-Hyu Cho
Paraneoplastic autoimmune multiorgan syndrome (PAMS), also known as paraneoplasic pemphigus, involves the skin, internal organs and mucosa. PAMS-associated mortality may occur as a result of autoantibody formation against internal tumors and their infiltration into organs other than the skin lesions that characterize PAMS. The most common symptoms of PAMS include pain associated with continuous oral ulceration and resistance to pharmacological treatment. The present study reports the case of a 42-year-old female patient who was admitted with an 8-month history of erosive skin lesions within the trunk region, oral mucosa and vaginal mucosa...
September 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/26877517/p-205-nephrotic-syndrome-revealing-hodgkin-s-disease
#2
S Toujani, F Daoud, Z Aydi, L Baili, B Ben Dhaou, F Boussema
OBJECTIFS: The association between paraneoplasic nephrotic syndrome and Hodgkin's disease is rare estimated to be about 0.5 to 1% (0.4% as minimal change disease and 0.1% as amyloid). MéTHODES: We report the case of an Hodgkin's disease revealed by an isolated nephrotic syndrome. RéSULTATS: A 34-year-old man presented with the clinical symptoms of nephrotic syndrome, Physical examination was notable for lower extremity edema. Though his hematologic evaluation was consistent with anemia (white blood cells = 11300/mm(3); hemoglobin, 7,9g/dL; platelets, 482000/mm(3)), there was no evidence of hemolysis but a biologic inflammatory syndrome...
December 2015: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/26777972/cyclooxygenase-2-expression-in-non-small-cell-lung-cancer-correlates-with-hypertrophic-osteoarthropathy
#3
Ioannis Rotas, Giovanni Cito, Igor Letovanec, Michel Christodoulou, Jean Y Perentes
Hypertrophic osteoarthrpathy (HO) is a rare paraneoplasic syndrome associated with non-small cell lung cancer (NSCLC). The pathophysiology of HO is unknown but was recently related to enhanced levels of urine prostaglandin E2 (PGE2). Here, we report the case of a patient that presented HO in association with a resectable left upper lobe NSCLC. Following surgery and adjuvant chemotherapy, HO resolved and did not recur with development of a brain metastasis 1 year later. Interestingly, tumor cyclooxygenase-2, an enzyme responsible the synthesis of PGE2, was expressed in the primary tumor but not in the resected metastasis...
February 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/26279697/ga68-dota-peptide-pet-ct-to-detect-occult-mesenchymal-tumor-inducing-osteomalacia-a-case-series-of-three-patients
#4
Chi Long Ho
Tumor-induced osteomalacia (TIO) is a rare disease that manifests with paraneoplasic syndrome and overproduction of fibroblast growth factor 23 (FGF23), leading to renal phosphate wasting and hyperphosphaturia, eventually leading to acquired hypophosphatemic osteomalacia. Diagnosis of this disease is often challenging because of the small size of the lesion, which can be localized in bone or soft tissue anywhere in the body. Detecting these occult mesenchymal tumors (OMT) is of great importance as they are potentially curable after tumor resection...
September 2015: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/23999024/-necrotizing-autoimmune-myopathies
#5
P Petiot, A Choumert, L Hamelin, P Devic, N Streichenberger
Necrotizing autoimmune myopathies are included in the spectrum of inflammatory myopathies, together with polymyosis, dermatopolymyosis and inclusion body myositis, despite the characteristic feature of marked muscular necrosis without inflammatory infiltrates. The clinical presentation is highly variable, often similar to the other inflammatory myopathies. The most common finding is nevertheless the severe form with rhabdomyolysis. The creatine kinase level is elevated (around 10,000IU/l) and electromyography shows myopathic changes with increased spontaneous activities reflecting the importance of the muscular necrosis...
August 2013: Revue Neurologique
https://www.readbyqxmd.com/read/23879060/-myocardial-infarction-in-colon-cancer
#6
O M Lazutina, L I Markova, O L Belaia, A B Bezprozvannyĭ, V V Variasin, A E Radzevich
Paraneoplastic syndromes have a variety of clinical manifestations most frequently resembling systemic diseases and phlebothrombosis. Also, hypercoagulative paraneoplasic syndrome may have some clinical features of myocardial infarction which makes difficult nosological diagnostics.
2013: Klinicheskaia Meditsina
https://www.readbyqxmd.com/read/22123569/-hodgkin-s-disease-revealed-by-a-nephrotic-syndrome-a-case-report-with-literature-review
#7
REVIEW
Hatim Nafil, Illias Tazi, Lahoucine Mahmal
The association between paraneoplasic nephrotic syndrome and Hodgkin's disease is rare. We report a case of Hodgkin's lymphoma in a young female patient with nephrotic syndrome. A 40-year-old woman presented with the clinical symptoms of nephrotic syndrome, kidney biopsy revealed minimal change glomerulonephritis. A treatment with prednisone was started but the response was partial. Twenty-four months after the diagnostic of nephrotic syndrome was made, she presented prolonged fever and weight loss, the physical examination showed cervical lymphadenopathy, which lymph node biopsy revealed Hodgkin lymphoma of the nodular sclerosing type...
November 2011: Annales de Biologie Clinique
https://www.readbyqxmd.com/read/21441056/crusted-norwegian-scabies-an-opportunistic-infection-with-tocilizumab-in-rheumatoid-arthritis
#8
Khadija Baccouche, Jérémie Sellam, Sarah Guegan, Sélim Aractingi, Francis Berenbaum
BACKGROUND: Crusted Norwegian scabies is an extremely rare hyperkeratotic variant of scabies infestation. We report herein a case of crusted scabies in a woman with severe rheumatoid arthritis (RA) treated by tocilizumab (TCZ), a monoclonal antibody blocking the interleukin-6 receptor. OBSERVATION: An 80-year-old female with severe RA developed erythroderma followed by hyperkeratosis, widespread scaling over the trunk, arms, hands and limbs, and crusted lesions on her scalp...
July 2011: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/19578602/tumor-induced-osteomalacia-a-case-report
#9
Daniel Dutra Romualdo-Silva, Bárbara Campolina Carvalho Silva, Cristiane Vasconcelos Caetano, Angélica Maria França Paiva Tibúrcio, Maurício Buzelin Nunes, Sérgio Almeida Pinheiro Chagas, Elizandra Tomazela Laurenti Polito, Antônio Rodrigues Ferreira, Saulo Purisch
Tumor-induced osteomalacia (TIO) is a rare paraneoplasic syndrome with overproduction of fibroblast growth factor 23 as a phosphaturic agent, leading to chronic hyperphosphaturia and hypophosphatemia, associated with inappropriately normal or low levels of 1,25-dihydroxyvitamin D. Diagnosis of this disease is often challenging. The following case report described a middle-aged man with symptoms of bone pain and severe muscle weakness, who was found to have TIO. The tumor responsible for the symptoms was localized on his thigh and its resection resulted in normalization of blood chemistry and complaints...
April 2009: Arquivos Brasileiros de Endocrinologia e Metabologia
https://www.readbyqxmd.com/read/18653203/-kleine-levin-syndrome-state-of-the-art
#10
REVIEW
I Arnulf, M Lecendreux, P Franco, Y Dauvilliers
INTRODUCTION: Kleine-Levin syndrome is a rare neurological disorder (1-2 cases per million inhabitants) primarily affecting young subjects. It is characterized by relapsing-remitting episodes of hypersomnia in association with cognitive and behavioral disturbances. Case-reports, small series, meta-analysis and a recent large, prospective trio study are consistent with a homogeneous, genuine disease entity. STATE OF THE ART: Patients are mostly male (68-78%) and adolescents (81%), with mean onset at 15 years (range 4-82 years)...
August 2008: Revue Neurologique
https://www.readbyqxmd.com/read/18383907/uncommon-epiloptogenic-lesions-affecting-the-temporal-lobe
#11
REVIEW
Ana Ramos, Federico Ballenilla, Patricia Martin
There are several processes implicated as uncommon causes of temporal lobe epilepsy. Trauma is the leading cause of epilepsy in young adults, intracerebral blood collection being the most consistent risk factor of seizures, especially subdural hematomas and brain contusions. Infarction is the entity most commonly related to epilepsy in the elderly population. Seizures usually present as complex seizures with high recurrence between 6 months and 2 years after stroke. There are some radiological characteristics of the affectation associated with high risk of early and late seizures...
February 2008: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/18355470/-neurogenic-electromyographic-activity-in-a-patient-with-non-paraneoplasic-lambert-eaton-syndrome
#12
B Lapergue, J-P Lefaucheur, A Bourahoui, T Nordine, H Hosseini, A Créange
INTRODUCTION: Lambert-Eaton myasthenic syndrome (LEMS) is a rare presynaptic disorder of the neuromuscular junction. Electrodiagnosis is characterized by compound muscle action potentials of small amplitude at rest, normalizing immediately after brief exercise or high-rate nerve stimulation. Needle electromyographic (EMG) activity is classically described as normal or myogenic. CASE: We report the case of a young patient with a non-paraneoplastic LEMS in whom the initial electroneuromyographic examination showed neurogenic changes in needle EMG concomitant with typical features of presynaptic neuromuscular junction disorder at single and repetitive nerve stimulation...
December 2007: Revue Neurologique
https://www.readbyqxmd.com/read/18351188/-colorectal-epidermoid-carcinoma-and-paraneoplastic-hypercalcemia
#13
J Gatlez, A Hendlisz, H Legendre, N Sirtaine, S Debroux, A Awada
The squamous cell carcinoma and the adenosquamous cell carcinoma of the colon and rectum are not well know and rare tumours. We report a case of squamous cell carcinoma of the recto-sigmoid who relapses in the liver after surgery of the primary tumour with paraneoplasic hypercalcaemia. We will discuss the pathogenesis, prognosis, associated conditions, clinical features and treatment strategies of squamous and adenosquamous cell carcinoma of the colon and the rectum.
November 2007: Acta Clinica Belgica
https://www.readbyqxmd.com/read/18341977/-long-term-evolution-of-achalasia-of-the-lower-esophageal-sphincter-and-intestinal-paraneoplasic-pseudo-obstruction-revealing-small-cell-lung-carcinoma
#14
N Ceze, L D'Alteroche, L Picon, P Magro, C Monégier du Sorbier, E-H Metman
We report a case of a small cell carcinoma of the lung revealed by chronic intestinal pseudo-obstruction associated with achalasia of the lower esophageal sphincter. Tumoral remission was achieved for more than 21 months after chemoradiotherapy but this did not prevent the paraneoplasic syndrome from persisting and medical treatment was not successful in treating the intestinal pseudo-obstruction or the dysphagia, which was not improved by esophageal dilation.
January 2008: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/18341976/-chronic-intestinal-pseudo-obstruction-and-anti-hu-syndrome-13-years-of-follow-up-without-neoplasia
#15
A Amiot, F Joly, B Messing, H Sokol, A Lavergne-Slove, J-Y Delattre, Y Bouhnik
Chronic intestinal pseudo-obstruction (CIPO) is a heterogeneous group of rare disorders characterised by symptoms of intestinal obstruction with no mechanical evidence of obstruction. It is caused by ineffective intestinal contractions due to visceral neuropathy and/or neuropathy. In adults, CIPO is mostly secondary. The most common causes are metabolic disorders, connective tissue disorders, neuropathic drug related injuries, paraneoplasic and post-infectious syndromes and amyloidosis. Secondary forms of CIPO have been reported with anti-Hu antibodies...
January 2008: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/17590135/-paraneoplasic-cerebellar-degeneration-as-a-presentation-of-breast-cancer-recurrence
#16
REVIEW
I Gázquez Sisteré, S Caro Orozco, D Márquez Medina, J Chordá Ribelles, A Quílez Martínez
Paraneoplastic cerebellar degeneration (PCD) is a rare condition which is characterised by global cerebellar dysfunction. Patients may present with these syndromes months or years before the diagnosis of underlying malignancy is established. Less often, PCD occurs in patients with a known malignancy or heralds the onset of a recurrence. The presence of specific antibodies in serum simples helps to guide identification the occult malignancy. We report here the case of a PCD in 74-year-old lady underwent a left mastectomy for breast cancer 5 years ago...
March 2007: Anales de Medicina Interna: Organo Oficial de la Sociedad Española de Medicina Interna
https://www.readbyqxmd.com/read/17511385/-cancer-associated-retinopathy-car-two-clinical-cases-and-review-of-the-literature
#17
REVIEW
G Matus, M Dicato, C Focan
The cancer associated retinopathy (CAR) is a paraneoplasic retinopathy in which an antigen-antibody reaction, due to retinal antigens, also expressed in tumours, leads to degeneration of retinal photoreceptor cells. We observed in CHL-Luxembourg, 2 clinical cases of non-Hodgkin's lymphoma with severe prognosis in whom we described the presence of anti-recoverin antibodies. The CAR is most frequently associated with small cell lung and ovarian carcinomas. Clinical symptoms (phosphenes, progressive loss of eyesight) sometimes, occur before the diagnostics of primary cancer...
March 2007: Revue Médicale de Liège
https://www.readbyqxmd.com/read/17417923/-chronic-intestinal-pseudo-obstruction
#18
REVIEW
M T Muñoz, J A Solís Herruzo
Chronic intestinal pseudo-obstruction (CIPO) is a syndrome characterized by the presence of recurrent episodes of clinical intestinal obstruction in the absence of obstructive lesions. Although this syndrome is rare, it causes a high morbidity. It is caused by a disturbance of the intestinal motility, that results in a failure of the progression of the intestinal content. Basically, the failure of the intestinal motility is a consequence of muscular disorder, neurological disorder or both. Usually, CIPO is secondary to other systemic disease; however, in the last years, many cases of primary CIPO have been described...
February 2007: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/16977969/-limphomatous-meningitis-as-recurrence-site-in-hodgkin-s-disease
#19
Martín Greco, Matías Valsecchi, Cecilia Niccodemi, José Presas, Claudia Corrado, Martín Winkel
Intracraneal manifestations of Hodgkin's Disease (HD) are extremely rare, with an estimated incidence rate of approximately 0.5%. They can be classified as: 1) treatment-related leucoencephalopathy, 2) central nervous system infections, 3) paraneoplasic syndromes and 4) intracraneal lymphomas, which could be sub-classified into intraparenchymal or intradural masses. We describe a case of a 40 year-old male with mixed cellularity type HD who developed neurological manifestations as relapsed disease. Magnetic resonance imaging suggested leptomeningeal metastases and atypical cells were found in cerebrospinal fluid...
2006: Medicina
https://www.readbyqxmd.com/read/16840918/-cushing-s-syndrome-due-to-a-pulmonary-carcinoid
#20
A Chadli, L Alami, S El Aziz, A Lazghad, H El Ghomari, M Kafih, F Essodegui, L Jabri, A Farouqi, F Marouan
Cushing paraneoplasic syndrome is a rare cause of hypercorticism. We report a case of 35 year-old man presenting with Cushing's syndrome characterized by severe signs of hypercorticism and hypokalemia. Endocrine investigations were suggestive of an hypercortisolism linked to an ectopic adrenocorticotropic (ACTH) secretion, both at baseline (mean ACTH levels=275 pg/ml, urinary free cortisol excretion=3.898 mmol/24 h) and after pharmacodynamic testing (lack of inhibition of ACTH by dexamethasone). Thoracic tomodensitometric examination revealed a 15 mm tumor corresponding to a neuroendocrine pulmonary carcinoid with positive immunostaining for chromogranin A...
June 2006: Annales D'endocrinologie
keyword
keyword
86792
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"