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https://www.readbyqxmd.com/read/29781887/speculations-on-the-future-of-psychiatric-diagnosis
#1
A John Rush, Hisham M Ibrahim
The Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-V), criterion symptom listings are frequently used in clinical practice as checklists to make diagnoses. However, most DSM-V conditions are, in fact, syndromes, that is, collections of signs and symptoms that commonly occur together in the clinic. This report discusses the value of syndromes in medicine and psychiatry. It is argued that a more precise future enumeration of brain circuits and the pathogenesis of psychiatric conditions will help us better understand and treat psychiatric syndromes, but they are unlikely to eliminate the need to categorize psychiatric conditions...
May 17, 2018: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/29772715/effects-of-sparassis-crispa-in-medical-therapeutics-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#2
Le Thi Nhu Ngoc, You-Kwan Oh, Young-Jong Lee, Young-Chul Lee
In this study, we investigated the therapeutic potential and medical applications of Sparassis crispa ( S. crispa ) by conducting a systematic review of the existing literature and performing a meta-analysis. The original efficacy treatment of the mushroom extract is considered primarily and searched in electronic databases. A total of 623 articles were assessed, 33 randomized controlled experiments were included after the manual screening, and some papers, review articles, or editorials that did not contain data were excluded...
May 16, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29765874/predictive-variables-for-sonographically-guided-corticosteroid-injection-in-mild-to-moderate-carpal-tunnel-syndrome
#3
Seong Yun Chung, Jung Min Kwak, Seok Kang, Seong-Ho Son, Jae Do Kim, Joon Shik Yoon
Objective: To assess the predictive variables after sonographically guided corticosteroid injection in carpal tunnel syndrome. Methods: A prospective, observational study was carried out on 25 wrists of 20 consecutive patients with carpal tunnel syndrome, confirmed by the American Association of Neuromuscular and Electrodiagnostic Medicine criteria, which includes clinical history, symptoms, and evidence of slowing of distal median nerve conduction. Visual analogue scale (VAS) and Boston Carpal Tunnel Questionnaire (BCTQ) were asked to the patients before and 4 weeks after the procedure...
April 2018: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29747035/microscale-radiosynthesis-preclinical-imaging-and-dosimetry-study-of-18-f-ambf-3-tate-a-potential-pet-tracer-for-clinical-imaging-of-somatostatin-receptors
#4
Ksenia Lisova, Maxim Sergeev, Susan Evans-Axelsson, Andreea D Stuparu, Seval Beykan, Jeffrey Collins, Jason Jones, Michael Lassmann, Ken Herrmann, David Perrin, Jason T Lee, Roger Slavik, R Michael van Dam
BACKGROUND: Peptides labeled with positron-emitting isotopes are emerging as a versatile class of compounds for the development of highly specific, targeted imaging agents for diagnostic imaging via positron-emission tomography (PET) and for precision medicine via theranostic applications. Despite the success of peptides labeled with gallium-68 (for imaging) or lutetium-177 (for therapy) in the clinical management of patients with neuroendocrine tumors or prostate cancer, there are significant advantages of using fluorine-18 for imaging...
April 20, 2018: Nuclear Medicine and Biology
https://www.readbyqxmd.com/read/29724214/multiple-challenges-of-antibiotic-use-in-a-large-hospital-in-ethiopia-a-ward-specific-study-showing-high-rates-of-hospital-acquired-infections-and-ineffective-prophylaxis
#5
Girma Gutema, Helle Håkonsen, Ephrem Engidawork, Else-Lydia Toverud
BACKGROUND: This project aims to study the use of antibiotics in three clinical wards in the largest tertiary teaching hospital in Ethiopia for a period of 1 year. The specific aims were to assess the prevalence of patients on antibiotics, quantify the antibiotic consumption and identify the main indications of use. METHOD: The material was all the medical charts (n = 2231) retrieved from three clinical wards (internal medicine, gynecology/obstetrics and surgery) in Tikur Anbessa Specialized Hospital (TASH) in Addis Ababa between September 2013 and September 2014...
May 3, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29719306/identifying-the-factors-affecting-papers-citability-in-the-field-of-medicine-an-evidence-based-approach-using-200-highly-and-lowly-cited-papers
#6
Mousa Yaminfirooz, Farzaneh Raeesi Ardali
Introduction: Nowadays, publishing highly-cited papers is important for researchers and editors. In this evidence-based study, the factors influencing the citability of published papers in the field of medicine have been identified. Material and Methods: 200 papers indexed in Scopus (in two groups: highly-cited and lowly-cited) with 100 papers in each were studied. Needed data were manually collected with a researcher-made checklist. Data analysis was done in SPSS using descriptive and inferential statistics...
2018: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/29713172/gender-specific-association-of-functional-prodynorphin-68-bp-repeats-with-cannabis-exposure-in-an-african-american-cohort
#7
Vadim Yuferov, Eduardo R Butelman, Mary Jeanne Kreek
Background: Cannabis use disorders (CUDs) cause substantial neuropsychiatric morbidity and comorbidity. There is evidence for gender-based differences in CUDs, for instance, a greater prevalence in males than in females. The main active component of cannabis is delta 9-tetrahydrocannabinol (delta 9-THC), a partial agonist of the cannabinoid type 1 receptor. Preclinical studies show that genetic or pharmacological manipulation of the kappa opioid receptor/dynorphin system modulates the effects of delta 9-THC...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29695374/relevance-of-trust-marks-and-ce-labels-in-german-language-store-descriptions-of-health-apps-analysis
#8
Urs-Vito Albrecht, Uta Hillebrand, Ute von Jan
BACKGROUND: In addition to mandatory CE marking ("CE" representing Conformité Européenne, with the CE marking being a symbol of free marketability in the European Economic Area) for medical devices, there are various seals, initiatives, action groups, etc, in the health app context. However, whether manufacturers use them to distinguish their apps and attach relevance to them is unclear. OBJECTIVE: The objective was to take a snapshot of quality seals, regulatory marks, and other orientation aids available on the German app market and to determine whether manufacturers deem such labels relevant enough to apply them to their apps, namely as reflected by mentions in app description texts in a typical app store (ie, Apple's App Store)...
April 25, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29678092/combining-semantic-and-lexical-methods-for-mapping-meddra-to-vcm-icons
#9
Jean-Baptiste Lamy, Rosy Tsopra
VCM (Visualization of Concept in Medicine) is an iconic language that represents medical concepts, such as disorders, by icons. VCM has a formal semantics described by an ontology. The icons can be used in medical software for providing a visual summary or enriching texts. However, the use of VCM icons in user interfaces requires to map standard medical terminologies to VCM. Here, we present a method combining semantic and lexical approaches for mapping MedDRA to VCM. The method takes advantage of the hierarchical relations in MedDRA...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29676942/pharmacotherapy-for-schizophrenia-in-postmenopausal-women
#10
Alexandre González-Rodríguez, Mary V Seeman
Reduced estrogen levels at menopause mean a loss of the neuroprotection that is conferred, from puberty until menopause, on women with schizophrenia. The postmenopausal stage of schizophrenia requires therapeutic attention because women with this diagnosis almost invariably experience increased symptoms and increased side effects at this time. So far, few targeted therapies have been successfully developed. Areas covered: This non-systematic, narrative review is based on the relevant published literature indexed in PubMed...
April 20, 2018: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/29673201/iot-on-board-system-for-driving-style-assessment
#11
Bartosz Jachimczyk, Damian Dziak, Jacek Czapla, Pawel Damps, Wlodek J Kulesza
The assessment of skills is essential and desirable in areas such as medicine, security, and other professions where mental, physical, and manual skills are crucial. However, often such assessments are performed by people called “experts” who may be subjective and are able to consider a limited number of factors and indicators. This article addresses the problem of the objective assessment of driving style independent of circumstances. The proposed objective assessment of driving style is based on eight indicators, which are associated with the vehicle’s speed, acceleration, jerk, engine rotational speed and driving time...
April 17, 2018: Sensors
https://www.readbyqxmd.com/read/29670898/effects-of-withania-somnifera-on-reproductive-system-a-systematic-review-of-the-available-evidence
#12
REVIEW
Ramin Nasimi Doost Azgomi, Afshar Zomorrodi, Hossein Nazemyieh, Seyed Mohammad Bagher Fazljou, Homayoun Sadeghi Bazargani, Fatemeh Nejatbakhsh, Arezoo Moini Jazani, Yadollah Ahmadi AsrBadr
Introduction: Withania somnifera (WS) also known as ashwagandha is a well-known medicinal plant used in traditional medicine in many countries for infertility treatment. The present study was aimed at systemically reviewing therapeutic effects of WS on the reproductive system. Methods: This systematic review study was designed in 2016. Required data were obtained from PubMed, Scopus, Google Scholar, Cochrane Library, Science Direct, Web of Knowledge, Web of Science, and manual search of articles, grey literature, reference checking, and expert contact...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29667600/is-eye-lens-dosimetry-needed-in-nuclear-medicine
#13
Malgorzata Wrzesien, Leszek Krolicki, Lukasz Albiniak, Jerzy Olszewski
INTRODUCTION: The specificity of personnel exposure, which distinguishes nuclear medicine, is associated with the form of the radiation source used, and this often requires performing manual procedures while using radioactive isotopes. The variety of radionuclides and medical procedures, and the yearly increase in the number of patients, as well as the change of the individual dose limit for the lens of the eye from a value of 150 mSv per year to a level of 20 mSv, means that issues of eye lens routine dosimetry become interesting from the radiation protection point of view...
April 18, 2018: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/29664087/a-linear-concentration-gradient-generator-based-on-multi-layered-centrifugal-microfluidics-and-its-application-in-antimicrobial-susceptibility-testing
#14
Minghui Tang, Xinyu Huang, Qian Chu, Xinghai Ning, Yuye Wang, Siu-Kai Kong, Xuping Zhang, Guanghui Wang, Ho-Pui Ho
In almost any branch of chemistry or life sciences, it is often necessary to study the interaction between different components in a system by varying their respective concentrations in a systematic manner. Currently, many procedures for generating a series of samples of different solute concentration levels are still done manually by dilution. To address this issue, we present herein a highly automated linear concentration gradient generator based on centrifugal microfluidics. The operation of this device is based on the use of multi-layered microfluidics in which individual fluidic samples to be mixed together are stored and metered in their respective layers before finally being transferred to a mixing chamber...
April 17, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29659856/integration-of-physical-abuse-clinical-decision-support-into-the-electronic-health-record-at-a-tertiary-care-children-s-hospital
#15
Srinivasan Suresh, Richard A Saladino, Janet Fromkin, Emily Heineman, Tom McGinn, Rudolph Richichi, Rachel P Berger
Objective: To evaluate the effect of a previously validated electronic health record-based child abuse trigger system on physician compliance with clinical guidelines for evaluation of physical abuse. Methods: A randomized controlled trial (RCT) with comparison to a preintervention group was performed. RCT-experimental subjects' providers received alerts with a direct link to a physical abuse-specific order set. RCT-control subjects' providers had no alerts, but could manually search for the order set...
April 12, 2018: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29657471/arthroscopic-knotless-rotator-cuff-repair-factors-associated-with-construct-selection-and-recent-trends-from-a-manual-review-of-1617-cases
#16
Sarav S Shah, Aalok Shah, Vivek Chadayammuri, Marlena McGill, Nicole Wei, David V Tuckman, Nicholas A Sgaglione
Purpose: Our aim was to identify predictors of construct selection and recent trends for arthroscopic knotless rotator cuff repair (RCR). Methods: A manual review of 1617 operative reports was performed. Results: A medium-sized tear had a threefold increase in odds of single row (SR) knotless repair (OR, 6.91; p = 0.009) versus SR knotted (OR, 3.05; p = 0.003). Generalist orthopaedic surgeons were 79% less likely to perform SR knotless repairs versus sports medicine trained specialists (p < 0...
March 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29657434/inventory-of-lice-of-mammals-and-farmyard-chicken-in-north-eastern-algeria
#17
Mohamed Nadir Meguini, Souad Righi, Fayçal Zeroual, Khelaf Saidani, Ahmed Benakhla
Background and Aim: Lice are permanent ectoparasites, extremely specific to their hosts. Their great importance in veterinary medicine remain significant, they can cause their direct pathogenic actions like irritability, dermatitis, anemia, decreased weight gain, and milk production. The purpose of this work was to made the first time an inventory of mammalian lice in North-eastern Algeria. Materials and Methods: Our survey of lice infestation was conducted on several animal species from five provinces of North-eastern Algeria...
March 2018: Veterinary World
https://www.readbyqxmd.com/read/29649979/ginseng-genome-database-an-open-access-platform-for-genomics-of-panax-ginseng
#18
Murukarthick Jayakodi, Beom-Soon Choi, Sang-Choon Lee, Nam-Hoon Kim, Jee Young Park, Woojong Jang, Meiyappan Lakshmanan, Shobhana V G Mohan, Dong-Yup Lee, Tae-Jin Yang
BACKGROUND: The ginseng (Panax ginseng C.A. Meyer) is a perennial herbaceous plant that has been used in traditional oriental medicine for thousands of years. Ginsenosides, which have significant pharmacological effects on human health, are the foremost bioactive constituents in this plant. Having realized the importance of this plant to humans, an integrated omics resource becomes indispensable to facilitate genomic research, molecular breeding and pharmacological study of this herb...
April 12, 2018: BMC Plant Biology
https://www.readbyqxmd.com/read/29630066/the-microbe-directory-an-annotated-searchable-inventory-of-microbes-characteristics
#19
Heba Shaaban, David A Westfall, Rawhi Mohammad, David Danko, Daniela Bezdan, Ebrahim Afshinnekoo, Nicola Segata, Christopher E Mason
The Microbe Directory is a collective research effort to profile and annotate more than 7,500 unique microbial species from the MetaPhlAn2 database that includes bacteria, archaea, viruses, fungi, and protozoa. By collecting and summarizing data on various microbes' characteristics, the project comprises a database that can be used downstream of large-scale metagenomic taxonomic analyses, allowing one to interpret and explore their taxonomic classifications to have a deeper understanding of the microbial ecosystem they are studying...
January 5, 2018: Gates open research
https://www.readbyqxmd.com/read/29628883/achieving-accurate-automatic-sleep-staging-on-manually-pre-processed-eeg-data-through-synchronization-feature-extraction-and-graph-metrics
#20
Panteleimon Chriskos, Christos A Frantzidis, Polyxeni T Gkivogkli, Panagiotis D Bamidis, Chrysoula Kourtidou-Papadeli
Sleep staging, the process of assigning labels to epochs of sleep, depending on the stage of sleep they belong, is an arduous, time consuming and error prone process as the initial recordings are quite often polluted by noise from different sources. To properly analyze such data and extract clinical knowledge, noise components must be removed or alleviated. In this paper a pre-processing and subsequent sleep staging pipeline for the sleep analysis of electroencephalographic signals is described. Two novel methods of functional connectivity estimation (Synchronization Likelihood/SL and Relative Wavelet Entropy/RWE) are comparatively investigated for automatic sleep staging through manually pre-processed electroencephalographic recordings...
2018: Frontiers in Human Neuroscience
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