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https://www.readbyqxmd.com/read/28637045/effects-of-injection-of-gamma-aminobutyric-acid-agonists-into-the-nucleus-accumbens-on-naloxone-induced-morphine-withdrawal
#1
Betilay Topkara, Hasan R Yananli, Eren Sakallı, Mehluge Caferova
AIMS: This study was to investigate the effects of local administration of gamma-aminobutyric acid (GABA) agonists into the nucleus accumbens (NAc) on naloxone-induced morphine withdrawal symptoms. METHODS: Bilateral guide cannulas were stereotaxically implanted in the shell or core regions of the NAc of Sprague-Dawley rats. After a recovery period, 3 morphine pellets, each consisting of 75 mg morphine base, were placed subcutaneously on the first and third days of the study with the rats under mild ether anaesthesia...
June 22, 2017: Pharmacology
https://www.readbyqxmd.com/read/28636262/increased-renal-concentrating-ability-after-long-term-oral-desmopressin-lyophilisate-treatment-contributes-to-continued-success-for-monosymptomatic-nocturnal-enuresis
#2
Hirokazu Ikeda, Tsuneki Watanabe, Keiichi Isoyama
OBJECTIVES: To investigate renal concentrating ability after long-term fast-melting oral desmopressin lyophilisate treatment in children with monosymptomatic nocturnal enuresis. METHODS: The present retrospective study involved 58 children (43 boys, 15 girls; aged 6-12 years) with nocturnal enuresis receiving oral desmopressin lyophilisate. After treatment for 4 weeks with a complete response, patients were placed on a reduced dose of 120 μg on alternate days. Moring urine osmolality was measured using urine samples obtained after medication and non-medication dry nights...
June 21, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28634090/evaluation-of-the-effect-of-3-month-bladder-basic-advice-in-children-with-monosymptomatic-nocturnal-enuresis
#3
Marcin Tkaczyk, Michał Maternik, Anna Krakowska, Agnieszka Wosiak, Monika Miklaszewska, Katarzyna Zachwieja, Dariusz Runowski, Anna Jander, Dariusz Ratajczak, Agata Korzeniecka-Kozyrska, Izabella Mader-Wołyńska, Katarzyna Kiliś-Pstrusińska
INTRODUCTION: Advice (BBA) into the standards of patients' care in both monosymptomatic and non-monosymptomatic nocturnal enuresis. Although the idea of this recommendation was clear and reflects clinical experience, duration and efficacy have not been definitely established. Recent data have demonstrated the lack of efficacy of BBA and a fierce discussion has ensued. The present study was aimed to assess the efficacy of BBA in a group of previously untreated children with primary monosymptomatic nocturnal enuresis (MNE)...
June 1, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28630441/overcoming-the-biological-aging-of-titanium-using-a-wet-storage-method-after-ultraviolet-treatment
#4
Sung-Hwan Choi, Won-Seok Jeong, Jung-Yul Cha, Jae-Hoon Lee, Kee-Joon Lee, Hyung-Seog Yu, Eun-Ha Choi, Kwang-Mahn Kim, Chung-Ju Hwang
We evaluated whether the biological activity of the surface of titanium, when stored in an aqueous solution after ultraviolet (UV) treatment, is comparable to that of the surface immediately after UV treatment. We subjected Grade IV titanium discs with machined surfaces to UV radiation for 15 min and then tested them immediately and after storage for 28 days, with and without distilled H2O (dH2O). We evaluated the surface characteristics using surface profiling, contact angle analysis, X-ray photoelectron spectroscopy, and in terms of the surface zeta-potential...
June 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28625988/modification-of-a-pollen-trap-design-to-capture-airborne-conidia-of-entomophaga-maimaiga-and-detection-by-quantitative-pcr
#5
Tonya D Bittner, Ann E Hajek, Andrew M Liebhold, Harold Thistle
The goal of this study was to develop effective and practical field sampling methods for quantifying aerial deposition of airborne conidia of Entomophaga maimaiga over space and time. This important fungal pathogen is a major cause of larval mortality in invasive gypsy moth (Lymantria dispar) populations in the United States. Airborne conidia of this pathogen are relatively large (similar in size to pollen) with unusual characteristics, requiring specialized methods for collection and quantification. Initially, dry sampling (settling of spores from the air onto a dry surface) was used to confirm the detectability of E...
June 16, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28621456/absorption-distribution-and-excretion-of-four-forms-of-titanium-dioxide-pigment-in-the-rat
#6
Thomas P Farrell, Berna Magnuson
Titanium dioxide (TiO2 ) is a white color additive that has a long history of global approval and use in food. There is, however, considerable confusion regarding the applicability of the biological effects of novel, engineered, nano-sized forms of TiO2 developed for nonpigmentary applications to the safety of oral exposure to food grade TiO2 pigment. The objective of this study was to assess the absorption, distribution, and routes of excretion in rats after oral exposure to food grade TiO2 . Four different grades of TiO2 (200 ppm) or control (0 ppm) diets were fed to rats for 7 consecutive days, followed by control diet only for 1, 24, or 72 h...
June 16, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28620484/the-effect-of-changing-the-moisture-levels-of-dry-extruded-and-wet-canned-diets-on-physical-activity-in-cats
#7
D G Thomas, M Post, G Bosch
Obesity levels in cats are increasing and the main causative factor is higher energy intake v. energy expenditure over time. Therefore, altering energy expenditure by enhancing physical activity of the cat could be a strategy to reduce obesity. Hydrating commercial dry diets with water increased activity in cats; however, no study has compared this approach with feeding high-moisture canned diets. Eight healthy male neutered domestic shorthair cats were fed four different dietary treatments in a Latin square design...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/28617290/micro-zooplankton-grazing-as-a-means-of-fecal-bacteria-removal-in-stormwater-bmps
#8
Jade M Burtchett, Michael A Mallin, Lawrence B Cahoon
A priority for environmental managers is control of stormwater runoff pollution, especially fecal microbial pollution. This research was designed to determine if fecal bacterial grazing by micro-zooplankton is a significant control on fecal bacteria in aquatic best management practices (BMPs); if grazing differs between a wet detention pond and a constructed wetland; and if environmental factors enhance grazing. Both 3-day grazing tests and 24-h dilution assays were used to determine grazing differences between the two types of BMP...
June 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28615097/-protective-effect-of-quercetin-against-seawater-instillation-induced-acute-lung-injury-through-preventing-m1-polarization-of-macrophages-in-mice
#9
Baojian Wang, Xu Mao
Objective To study the protective effect of quercetin against seawater instillation-induced acute lung injury (SW-ALI) and explore the roles of M1polarization of macrophages and M1 macrophage-mediated inflammation in the protective effect. Methods Male C57BL/6 mice were randomly divided into four groups, normal control group, quercetin-treated group, SW-ALI group, SW-ALI and quercetin-treated group, with 15 mice in each group. The mice were intraperitoneally injected with 1 g/L pentobarbital sodium, and then seawater was injected into the lungs through oropharyngeal intubation at the concentration of 4 mL/kg...
June 2017: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
https://www.readbyqxmd.com/read/28599898/a-randomized-open-label-controlled-trial-of-chlorhexidine-alcohol-versus-povidone-iodine-for-cesarean-antisepsis-the-capica-trial
#10
Edward H Springel, Xiao-Yu Wang, Vanessa M Sarfoh, Bradley P Stetzer, Steven A Weight, Brian M Mercer
BACKGROUND: Identification of optimal surgical site antisepsis preparations may reduce cesarean-related surgical site infections. Two recently published investigations examined efficacy of chlorhexidine-alcohol and iodine-alcohol preparations. No previous randomized controlled trial has compared chlorhexidine-alcohol to povidone-iodine aqueous scrub and paint in reduction of cesarean-related surgical site infection. OBJECTIVE: The purpose of the study was to determine if chlorhexidine-alcohol would result in less surgical site infections than povidone-iodine when used as skin antisepsis preparation prior to cesarean delivery...
June 6, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28596011/emmenagogue-properties-of-milicia-excelsa-welw-c-c-berg-moraceae-based-at-least-in-part-on-its-ability-to-correlate-the-activity-of-the-hypothalamic-pituitary-axis-to-that-of-the-ovaries
#11
Marie Alfrede Mvondo, Aude Jaelle Touomo Sakock, Sylvin Benjamin Ateba, Charline Florence Awounfack, Telesphore Nanbo Gueyo, Dieudonné Njamen
ETHNOPHARMACOLOGICAL RELEVANCE: Milicia excelsa (Welw.) C.C. Berg (Moraceae) is a medicinal plant recommended over tropical Africa as a cure for several ailments including amenorrhea. This is the hallmark of an ovarian lesion or a dysfunction of the hypothalamic-pituitary-ovarian axis which may lead to infertility, osteoporosis or endometrial cancer. However, regardless these traditional claims, no scientific report dealing with emmenagogue properties has been reported yet. AIM OF THE STUDY: To bring scientific evidence to the curative action of the plant, we proposed evaluating the effects of a root aqueous extract of Milicia excelsa on female Wistar rat sexual maturation...
June 6, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28595332/ability-to-discriminate-between-sustainable-and-unsustainable-heat-stress-exposures-part-1-wbgt-exposure-limits
#12
Ximena P Garzón-Villalba, Yougui Wu, Candi D Ashley, Thomas E Bernard
Objectives: Heat stress exposure limits based on wet-bulb globe temperature (WBGT) were designed to limit exposures to those that could be sustained for an 8-h day using limited data from Lind in the 1960s. In general, Sustainable exposures are heat stress levels at which thermal equilibrium can be achieved, and Unsustainable exposures occur when there is a steady increase in core temperature. This paper addresses the ability of the ACGIH® Threshold Limit Value (TLV®) to differentiate between Sustainable and Unsustainable heat exposures, to propose alternative occupational exposure limits, and ask whether an adjustment for body surface area improves the exposure decision...
June 8, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/28592929/le-ciment-br%C3%A3-le-toujours
#13
T Lebreton, M Fontaine, R Le Floch
Cement burn is a common cause of chemical burns in France. They usually need surgical treatment. This retrospective study was performed among 49 patients, aged 21-71 years, admitted to the St Joseph-St Luc Hospital in Lyon, France. Patients were mainly male, fairly young (mean 44 years) and had a professional activity, although burns usually occurred at home. Burns were deep, on the lower limbs, and were not extensive (3% TBS). All but one patient needed grafting, performed on d13. LOS was eight days. Seven patients had to be admitted to a rehabilitation centre afterwards...
March 31, 2017: Annals of Burns and Fire Disasters
https://www.readbyqxmd.com/read/28588629/in-vitro-and-in-vivo-activity-of-artemisia-sieberi-against-trichomonas-gallinae
#14
M R Youssefi, M Abouhosseini Tabari, A A Moghadamnia
In Iranian folk medicine Artemisia sieberi has been used for treatment of parasite infections in human and animals. The present study was designed to evaluate the in vitro and in vivo effects of A. sieberi essential oil (EO) against Trichomonas gallinae. Trichomonas gallinae were recovered by wet mount method from infected native pigeons. The in vitro assays were accomplished in multi-well plates containing metronidazole (MTZ) as a standard antitrichomonal and EO in final concentrations of 2.5, 5, 10, 20, 50, and 100 μg/ml of culture medium containing 10(4) parasites...
2017: Iranian journal of veterinary research
https://www.readbyqxmd.com/read/28588447/the-effects-of-epidermal-neural-crest-stem-cells-on-local-inflammation-microenvironment-in-the-defected-sciatic-nerve-of-rats
#15
Yue Li, Dongdong Yao, Jieyuan Zhang, Bin Liu, Lu Zhang, Hua Feng, Bingcang Li
Cell-based therapy is a promising strategy for the repair of peripheral nerve injuries (PNIs). epidermal neural crest stems cells (EPI-NCSCs) are thought to be important donor cells for repairing PNI in different animal models. Following PNI, inflammatory response is important to regulate the repair process. However, the effects of EPI-NCSCs on regulation of local inflammation microenviroment have not been investigated extensively. In the present study, these effects were studied by using 10 mm defected sciatic nerve, which was bridged with 15 mm artificial nerve composed of EPI-NCSCs, extracellular matrix (ECM) and poly (lactide-co-glycolide) (PLGA)...
2017: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/28586070/protective-effect-of-diethylcarbamazine-inhibits-nf-%C3%AE%C2%BAb-activation-in-isoproterenol-induced-acute-myocardial-infarction-rat-model-through-the-parp-pathway
#16
Guowei Jia, Ming Zao, Xiaoyu Liu
The present study investigated the protective effect of diethylcarbamazine in inhibiting nuclear factor (NF)-κB activation in isoproterenol‑induced acute myocardial infarction (AMI) rats through the poly ADP ribose polymerase (PARP) pathway. Male albino Wistar rats were injected subcutaneously with isoproterenol (100 mg/kg/day) for 2 days to induce an AMI model. Diethylcarbamazine (50 mg/kg) was administered by gavage for 12 days prior to the isoproterenol-induced AMI. It was noted that diethylcarbamazine significantly inhibited AMI‑induced casein kinase and lactate dehydrogenase levels, and reduced the AMI‑induced wet heart weight to body weight ratio in AMI rats...
June 6, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28580784/doubly-reentrant-cavities-prevent-catastrophic-wetting-transitions-on-intrinsically-wetting-surfaces
#17
Eddy M Domingues, Sankara Arunachalam, Himanshu Mishra
Omniphobic surfaces, that is, which repel all known liquids, have proven of value in applications ranging from membrane distillation to underwater drag reduction. A limitation of currently employed omniphobic surfaces is that they rely on perfluorinated coatings, increasing cost and environmental impact and preventing applications in harsh environments. Thus, there is a keen interest in rendering conventional materials, such as plastics, omniphobic by micro/nanotexturing rather than via chemical makeup, with notable success having been achieved for silica surfaces with doubly reentrant micropillars...
June 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28579747/prevalence-of-and-risk-factors-for-age-related-macular-degeneration-in-nepal-the-bhaktapur-retina-study
#18
Raba Thapa, Sanyam Bajimaya, Govinda Paudyal, Shankar Khanal, Stevie Tan, Suman S Thapa, Ger van Rens
AIM: This study aimed to explore the prevalence of and risk factors for age-related macular degeneration (AMD) in an elderly population in Nepal. SUBJECTS AND METHODS: This is a population-based, cross-sectional study. A sample size of 2,100 was calculated. A total of 1,860 (88.6%) subjects aged >60 years were enrolled for the study from 30 clusters in the district. Detailed history, visual acuity, and anterior segment and posterior segment examinations were performed...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28579033/does-oxidative-stress-play-any-role-in-diabetic-cataract-formation-re-evaluation-using-a-thioltransferase-gene-knockout-mouse-model
#19
Jie Zhang, Hong Yan, Marjorie F Lou
Oxidative stress is a known risk factor in senile cataract formation. In recent years, it has been suggested that oxidation may also be associated with cataract induced by hyperglycemia, but this concept has not been well examined or validated. Since thioltransferase (TTase) is one of the key enzymes that regulates redox homeostasis and protects against oxidative stress in the lens, we have used TTase gene knockout (KO) mice as a model to examine this new concept. Lenses from 4 months old TTase KO and wild-type (WT) mice were incubated in TC199 culture medium containing 30 mM glucose for 48 h...
June 1, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28576713/adaptation-of-continuous-biogas-reactors-operating-under-wet-fermentation-conditions-to-dry-conditions-with-corn-stover-as-substrate
#20
Balázs Kakuk, Kornél L Kovács, Márk Szuhaj, Gábor Rákhely, Zoltán Bagi
Corn stover (CS) is the agricultural by-product of maize cultivation. Due to its high abundance and high energy content it is a promising substrate for the bioenergy sector. However, it is currently neglected in industrial scale biogas plants, because of its slow decomposition and hydrophobic character. To assess the maximum biomethane potential of CS, long-term batch fermentations were carried out with various substrate concentrations and particle sizes for 72 days. In separate experiments we adapted the biogas producing microbial community in wet fermentation arrangement first to the lignocellulosic substrate, in Continuous Stirred Tank Reactor (CSTR), then subsequently, by continuously elevating the feed-in concentration, to dry conditions in solid state fermenters (SS-AD)...
May 30, 2017: Anaerobe
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