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https://www.readbyqxmd.com/read/29332471/fatal-exertional-heat-stroke-and-american-football-players-the-need-for-regional-heat-safety-guidelines
#1
Andrew J Grundstein, Yuri Hosokawa, Douglas J Casa
CONTEXT:   Weather-based activity modification in athletics is an important way to minimize heat illnesses. However, many commonly used heat-safety guidelines include a uniform set of heat-stress thresholds that do not account for geographic differences in acclimatization. OBJECTIVE:   To determine if heat-related fatalities among American football players occurred on days with unusually stressful weather conditions based on the local climate and to assess the need for regional heat-safety guidelines...
January 13, 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29332276/variability-and-reliability-of-pop-concentrations-in-multiple-breast-milk-samples-collected-from-the-same-mothers
#2
Risa Kakimoto, Masayoshi Ichiba, Akiko Matsumoto, Kunihiko Nakai, Nozomi Tatsuta, Miyuki Iwai-Shimada, Momoko Ishiyama, Noriko Ryuda, Takashi Someya, Ieyasu Tokumoto, Daisuke Ueno
Risk assessment of infant using a realistic persistent organic pollutant (POP) exposure through breast milk is essential to devise future regulation of POPs. However, recent investigations have demonstrated that POP levels in breast milk collected from the same mother showed a wide range of variation daily and monthly. To estimate the appropriate sample size of breast milk from the same mother to obtain reliable POP concentrations, breast milk samples were collected from five mothers living in Japan from 2006 to 2012...
January 13, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29330444/lidocaine-enhances-the-effects-of-chemotherapeutic-drugs-against-bladder-cancer
#3
Xihua Yang, Lili Zhao, Meiping Li, Lei Yan, Shengwan Zhang, Zhenguo Mi, Liansheng Ren, Jun Xu
This study aimed to investigate whether lidocaine, alone or in combination with other chemotherapeutic agents, inhibits the growth of human bladder cancer cells in vitro and orthotopically transplanted bladder tumors in vivo. The effects of lidocaine (1.25, 2.5 or 5 mg/mL), mitomycin C (MMC, 0.66 mg/mL), pirarubicin (0.75 mg/mL) and Su Fu'ning lotion (SFN, 0.0625 mg/mL) on the proliferation of human bladder cancer (BIU-87) cells were studied using the MTT assay. A Balb/c nude mouse model of bladder cancer was developed by orthotopic transplantation of BIU-87 cells, and the effects of intravesical instillation of lidocaine and MMC on bladder wet weight (a measure of tumor size) and survival (over 60 days) were studied...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29328986/post-anaerobic-digestion-thermal-hydrolysis-of-sewage-sludge-and-food-waste-effect-on-methane-yields-dewaterability-and-solids-reduction
#4
Kine Svensson, Oda Kjørlaug, Matthew J Higgins, Roar Linjordet, Svein J Horn
Post-anaerobic digestion (PAD) treatment technologies have been suggested for anaerobic digestion (AD) to improve process efficiency and assure hygenization of organic waste. Because AD reduces the amount of organic waste, PAD can be applied to a much smaller volume of waste compared to pre-digestion treatment, thereby improving efficiency. In this study, dewatered digestate cakes from two different AD plants were thermally hydrolyzed and dewatered, and the liquid fraction was recirculated to a semi-continuous AD reactor...
January 4, 2018: Water Research
https://www.readbyqxmd.com/read/29322356/inherent-health-and-environmental-risk-assessment-of-nanostructured-metal-oxide-production-processes
#5
Mina Torabifard, Reza Arjmandi, Alimorad Rashidi, Jafar Nouri, Iraj Mohammadfam
The health and environmental effects of chemical processes can be assessed during the initial stage of their production. In this paper, the Chemical Screening Tool for Exposure and Environmental Release (ChemSTEER) software was used to compare the health and environmental risks of spray pyrolysis and wet chemical techniques for the fabrication of nanostructured metal oxide on a semi-industrial scale with a capacity of 300 kg/day in Iran. The pollution sources identified in each production process were pairwise compared in Expert Choice software using indicators including respiratory damage, skin damage, and environmental damages including air, water, and soil pollution...
January 10, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29320235/a-limited-survey-of-metal-content-in-blue-jack-mackerel-trachurus-picturatus-obtained-from-markets-in-the-canary-islands
#6
Carmen Rubio, Laura Acosta, Gara Luis-González, Dailos González-Weller, Consuelo Revert, Arturo Hardisson, Ángel Gutiérrez
The levels of 20 metals (aluminum, boron, barium, calcium, cadmium, cobalt, chromium, copper, iron, potassium, lithium, magnesium, manganese, molybdenum, sodium, nickel, lead, strontium, vanadium, and zinc) were analyzed in muscle and liver tissue of Trachurus picturatus marketed in the Canary Islands (Spain) by using inductively coupled plasma optical emission spectrometry. In the liver samples, the mean concentrations in milligrams per kilogram wet weight (wt) of Al (14.7), B (0.99), Ba (1.64), Ca (314), Cd (2...
January 10, 2018: Journal of Food Protection
https://www.readbyqxmd.com/read/29319595/pythium-keratitis-leading-to-fatal-cavernous-sinus-thrombophlebitis
#7
Anubha Rathi, Arunaloke Chakrabarti, Tushar Agarwal, Neelam Pushker, Mukesh Patil, Hemant Kamble, Jeewan S Titiyal, Rishi Mohan, Seema Kashyap, Sanjay Sharma, Seema Sen, Gita Satpathy, Namrata Sharma
PURPOSE: To report a case of Pythium insidiosum keratitis leading to fatal cavernous sinus thrombophlebitis. METHODS: Case report. RESULTS: A 70-year-old man presented with excruciating pain, redness, and diminution of vision in his left eye for 2 weeks after washing his hair with tap water. A total corneal ulcer with surrounding infiltrates and associated corneal thinning was present. Corneal scraping revealed the presence of Gram-positive cocci...
January 9, 2018: Cornea
https://www.readbyqxmd.com/read/29319050/consistency-between-sweat-rate-and-wet-bulb-globe-temperature-for-the-assessment-of-heat-stress-of-people-working-outdoor-in-arid-and-semi-arid-regions
#8
Hamidreza Heidari, Farideh Golbabaei, Aliakbar Shamsipour, Abbas Rahimi Forushani, Abbasali Gaeini
BACKGROUND: Heat stress is common among workers in arid and semi-arid areas. In order to take every preventive measure to protect exposed workers against heat-related disorders, it is crucial to choose an appropriate index that accurately relates environmental parameters to physiological responses. OBJECTIVE: To investigate the consistency between 2 heat stress and strain indices, ie, sweat rate and wet bulb globe temperature (WBGT), for the assessment of heat stress of people working outdoor in arid and semi-arid regions in Iran...
January 2018: International Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29318853/-effects-of-electroacupuncture-on-adaptive-hypertrophy-of-gastrocnemius-and-proliferation-and-differentiation-of-muscle-satellite-cells-in-rats
#9
Dan-Dan Zhao, Cheng-Lin Tang, Si-Qin Huang, Ao Luo, An-Ning Zhang, Quan-Hu Guo, Jing Cao, Rui-Qi Gao
OBJECTIVE: To explore the effects and mechanism of different duration electroacupuncture (EA) on adaptive hypertrophy of gastrocnemius and the expressions of proliferation cell nuclear antigen (PCNA), paired box transcription factor 7 (Pax 7), myogenic differentiation antigen (MyoD 1), myogenin (MyoG), myosin heavy chain-Ⅰ(Myh 7), transforming growth factor-β 1 (TGF-β 1), Smad 3 in rats. METHODS: Twenty-four SD adult male rats were randomly divided into normal, two-week EA (A 2), four-week EA (A 4) and eight-week EA (A 8) groups, 6 rats in each group...
December 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29307088/physiological-traits-of-endornavirus-infected-and-endornavirus-free-common-bean-phaseolus-vulgaris-cv-black-turtle-soup
#10
S Khankhum, R A Valverde
This study evaluated the physiological traits of eight lines of common bean (Phaseolus vulgaris) cv. Black Turtle Soup, four of which were double-infected with Phaseolus vulgaris endornavirus 1 and Phaseolus vulgaris endornavirus 2, and four of which were endornavirus-free. Plants from all eight lines were morphologically similar and did not show statistically significant differences in plant height, wet weight, number of days to flowering and pod formation, pods per plant, pod thickness, seed size, number of seeds per pod, and anthocyanin content...
January 6, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29305219/development-of-various-composition-multicomponent-chitosan-fish-collagen-glycerin-3d-porous-scaffolds-effect-on-morphology-mechanical-strength-biostability-and-cytocompatibility
#11
Saleem Ullah, Ismail Zainol, Shiplu Roy Chowdhury, M B Fauzi
The various composition multicomponent chitosan/fish collagen/glycerin 3D porous scaffolds were developed and investigated the effect of various composition chitosan/fish collagen/glycerin on scaffolds morphology, mechanical strength, biostability and cytocompatibility. The scaffolds were fabricated via freeze-drying technique. The effects of various compositions consisting in 3D scaffolds were investigated via FT-IR analysis, porosity, swelling and mechanical tests, and effect on the morphology of scaffolds investigated microscopically...
January 2, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29298073/polydopamine-and-polydopamine-silane-hybrid-surface-treatments-in-structural-adhesive-applications
#12
Ngon T Tran, David P Flanagan, Joshua A Orlicki, Joseph L Lenhart, Kenneth Proctor, Daniel Brainard Knorr
Numerous studies have focused on the remarkable adhesive properties of polydopamine, which can bind to substrates with a wide range of surface energies, even under aqueous conditions. This behavior suggests that polydopamine may be an attractive option as a surface treatment in structural bonding applications, where good bond durability is required. Here, we assessed polydopamine as a surface treatment for bonding aluminum plates with an epoxy resin. A model epoxy adhesive consisting of diglycidyl ether of bisphenol A (DGEBA), and Jeffamine® D230 polyetheramine was employed and lap shear measurements (ASTM D1002 10) were made (i) under dry conditions to examine initial bond strength and (ii) after exposure to hot/wet (63 oC in water for 14 days) conditions to assess bond durability...
January 3, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29290433/associations-between-management-practices-and-within-pen-prevalence-of-calf-diarrhea-and-respiratory-disease-on-dairy-farms-using-automated-milk-feeders
#13
Catalina Medrano-Galarza, Stephen J LeBlanc, Andria Jones-Bitton, Trevor J DeVries, Jeffrey Rushen, Anne Marie de Passillé, Marcia I Endres, Derek B Haley
Data on management practices used with automated milk feeders (AMF) are needed to identify factors associated with calf health in these systems. The objectives of this observational, longitudinal, cross-sectional study were to estimate the prevalence of calf diarrhea (CD) and bovine respiratory disease (BRD), and to identify factors associated with prevalence of these diseases at the pen level on dairy farms feeding milk to group-housed calves with AMF. Seventeen dairy farms with AMF in Ontario, Canada, were visited 4 times, seasonally, over 1 yr...
December 28, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29279718/lannea-acida-a-rich-anacardiaceae-ethanol-extract-exhibits-estrogenic-effects-and-prevents-bone-loss-in-an-ovariectomized-rat-model-of-osteoporosis
#14
Mouchili Riepouo Oumarou, Stéphane Zingue, Berlise Yengwa Bakam, Sylvin Benjamin Ateba, Simplice Harquin Foyet, Fritz Teddy Tchaptchet Mbakop, Dieudonné Njamen
Phytoestrogens have been shown to prevent postmenopausal osteoporosis. Lannea acida is a medicinal plant traditionally used in Cameroon to treat infertility, gynaecological complaints, and rheumatism. These uses prompted us to evaluate estrogenic activity of Lannea acida bark ethanolic extract and its antiosteoporotic potential in ovariectomized Wistar rats. In vitro, the E-screen assay was used to assess the ability of L. acida extract to induce MCF-7 cells proliferation. In vivo, a 3-day uterotrophic assay and a 12-week oral treatment in ovariectomized adult rats were carried out to evaluate the ability of L...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29278264/a-sprinkling-experiment-to-quantify-celerity-velocity-differences-at-the-hillslope-scale
#15
Willem J van Verseveld, Holly R Barnard, Chris B Graham, Jeffrey J McDonnell, J Renée Brooks, Markus Weiler
Few studies have quantified the differences between celerity and velocity of hillslope water flow and explained the processes that control these differences. Here, we asses these differences by combining a 24-day hillslope sprinkling experiment with a spatially explicit hydrologic model analysis. We focused our work on Watershed 10 at the H. J. Andrews Experimental Forest in western Oregon. Celerities estimated from wetting front arrival times were generally much faster than average vertical velocities of δ2H...
2017: Hydrol Earth Syst Sci
https://www.readbyqxmd.com/read/29273418/pirfenidone-protects-against-paraquat-induced-lung-injury-and-fibrosis-in-mice-by-modulation-of-inflammation-oxidative-stress-and-gene-expression
#16
Fateme Pourgholamhosein, Rokhsana Rasooli, Mostafa Pournamdari, Leyla Pourgholi, Mitra Samareh-Fekri, Mahmoud Ghazi-Khansari, Maryam Iranpour, Hamid-Reza Poursalehi, Mahmoud-Reza Heidari, Ali Mandegary
In this study we investigated the protective effects and possible mechanisms of pirfenidone (PF) in paraquat (PQ)-induced lung injury and fibrosis in mice. Lung injury was induced by injection of PQ (20 mg/kg). Thereafter, mice orally received water and PF (100 and 200 mg/kg) for four weeks. After 28 days, the inflammation and fibrosis were determined in the lungs by analysis of histopathology, bronchoalveolar lavage fluid (BALF) cell count, lung wet/dry weight ratio, hydroxyproline content, and oxidative stress biomarkers...
December 19, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29249870/effects-of-fty720-on-lung-injury-induced-by-hindlimb-ischemia-reperfusion-in-rats
#17
Liangrong Wang, Feifei Chen, Yafei Pan, Lina Lin, Xiangqing Xiong
Background: Sphingosine-1-phosphate (S1P) is a biologically active lysophospholipid mediator involved in modulating inflammatory process. We investigated the effects of FTY720, a structural analogue of S1P after phosphorylation, on lung injury induced by hindlimb ischemia reperfusion (IR) in rats. Methods: Fifty Sprague-Dawley rats were divided into groups SM, IR, F3, F5, and F10. Group SM received sham operation, and bilateral hindlimb IR was established in group IR...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/29247903/polychlorinated-naphthalenes-pcns-in-seafood-estimation-of-dietary-intake-in-korean-population
#18
Jongchul Kim, Eun-Su Shin, Sung-Deuk Choi, Jiping Zhu, Yoon-Seok Chang
Polychlorinated naphthalenes (PCNs) were measured in 33 seafood species including fish, mollusks and crustaceans purchased from local markets in five Korean cities between 2012 and 2013. Five samples were collected from each species for the measurements. Thirty-seven PCN congeners from tetra-CN to octa-CN were measured. Octa-CN (octachloronaphthalene) was not detected in any of the samples. Tetra-CN and penta-CN were the predominant homologues of PCNs in seafood samples with PCN 51 and PCN 52/60 being the most abundant congeners in the samples...
December 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29244747/ophthalmic-formulation-containing-nilvadipine-nanoparticles-prevents-retinal-dysfunction-in-rats-injected-with-streptozotocin
#19
Saori Deguchi, Hiroko Otake, Yosuke Nakazawa, Noriko Hiramatsu, Naoki Yamamoto, Noriaki Nagai
Retinopathy leads to irreparable vision loss via capillary closure and areas of nonperfusion. However, the current instillation systems do not allow a sufficient amount of drug required to treat retinopathy to reach the posterior segment (retina); therefore, a new formulation targeting the posterior segment is expected as therapy for retinopathy. We prepared ophthalmic formulations containing nilvadipine nanoparticles (NILnano), and demonstrated whether the instillation of NILnano can prevent retinal dysfunction in rats injected with excessive streptozotocin (STZ rats) in this study...
December 15, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29236164/the-influence-of-isoflavone-for-denervation-induced-muscle-atrophy
#20
Shinpei Tabata, Miki Aizawa, Masakazu Kinoshita, Yoshinori Ito, Yusuke Kawamura, Minoru Takebe, Weijun Pan, Kunihiro Sakuma
PURPOSE: Decrease in activity stress induces skeletal muscle atrophy. A previous study showed that treatment with a high level (20%) of isoflavone inhibits muscle atrophy after short-term denervation (at 4 days) in mice. The present study was designed to elucidate whether the dietary isoflavone aglycone (AglyMax) at a 0.6% prevents denervation-mediated muscle atrophy, based on the modulation of atrogin-1- or apoptosis-dependent signaling. METHODS: Mice were fed either a normal diet or 0...
December 13, 2017: European Journal of Nutrition
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