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https://www.readbyqxmd.com/read/29672753/pro-and-anti-androgenic-progestins-in-transgender-youth-differential-effects-on-body-composition-and-bone-metabolism
#1
Lloyd J W Tack, Margarita Craen, Bruno Lapauw, Stefan Goemaere, Kaatje Toye, Jean-Marc Kaufman, Sara Vandewalle, Guy T'Sjoen, Hans-Georg Zmierczak, Martine Cools
Context: Pro- and anti-androgenic progestins can be used to attenuate endogenous hormonal effects in late-pubertal transgender adolescents (Tanner stage B4/5 and G4/5). Currently, no data are available on the effects of progestins on the development of bone mass or body composition in trans youth. Objective: To study prospectively the evolution of body composition and bone mass in late-pubertal transgender adolescents using the pro- or anti-androgenic progestins lynestrenol (L) and cyproterone acetate (CA) respectively...
April 16, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29661941/mental-health-of-transgender-and-gender-nonconforming-youth-compared-with-their-peers
#2
Tracy A Becerra-Culqui, Yuan Liu, Rebecca Nash, Lee Cromwell, W Dana Flanders, Darios Getahun, Shawn V Giammattei, Enid M Hunkeler, Timothy L Lash, Andrea Millman, Virginia P Quinn, Brandi Robinson, Douglas Roblin, David E Sandberg, Michael J Silverberg, Vin Tangpricha, Michael Goodman
BACKGROUND: Understanding the magnitude of mental health problems, particularly life-threatening ones, experienced by transgender and/or gender nonconforming (TGNC) youth can lead to improved management of these conditions. METHODS: Electronic medical records were used to identify a cohort of 588 transfeminine and 745 transmasculine children (3-9 years old) and adolescents (10-17 years old) enrolled in integrated health care systems in California and Georgia. Ten male and 10 female referent cisgender enrollees were matched to each TGNC individual on year of birth, race and/or ethnicity, study site, and membership year of the index date (first evidence of gender nonconforming status)...
April 16, 2018: Pediatrics
https://www.readbyqxmd.com/read/29661940/disparities-for-lgbtq-and-gender-nonconforming-adolescents
#3
Laura Baams
OBJECTIVES: To identify patterns of childhood adversity in a sample of adolescents and assess disparities in these experiences for lesbian, gay, bisexual, transgender, and questioning adolescents and by level of gender nonconformity. METHOD: By using the cross-sectional, statewide, anonymous 2016 Minnesota Student Survey, 81 885 students were included in the current study (50.59% male; mean age = 15.51). Participants were enrolled in grades 9 and 11 in a total of 348 schools...
April 16, 2018: Pediatrics
https://www.readbyqxmd.com/read/29652872/medical-management-of-transgender-children-and-adolescents
#4
María Fernanda Castilla-Peón
Transgender or gender nonconforming (GN) persons identify themselves with a gender which is different from that correspondent to their birth sex. The demand for health services by families with transgender children or adolescents tends to increase. The prevalence of GN in children is unknown; however, it has been estimated to be > 1% in adolescents. Transgender persons are at increased risk of depression, suicide, illicit drug abuse, human immunodeficiency virus infection, and non-accidental injury. The most accepted model for the care of transgender persons assumes that these adverse outcomes are the consequence of social margination rather than the GI condition itself...
2018: Boletín Médico del Hospital Infantil de México
https://www.readbyqxmd.com/read/29575091/transgender-adolescents-and-acne-a-cases-series
#5
Lucía Campos-Muñoz, Diego López-De Lara, Marina L Rodríguez-Rojo, Alberto Conde-Taboada, Eduardo López-Bran
We describe the difficulties of treating acne in a series of female-to-male transgender adolescents, including concerns about potential hepatotoxicity with concomitant use of testosterone with isotretinoin or tetracyclines. Acne is a foreseeable adverse effect of testosterone treatment in transgender adolescents, so monitoring for acne is advised. The treatment of acne in transgender adolescents is important given that severe acne and transgenderism are associated with higher rates of depression and suicide...
March 25, 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29564711/documenting-an-epidemic-of-suffering-low-health-related-quality-of-life-among-transgender-youth
#6
Yuanshu Zou, Rhonda Szczesniak, Alexis Teeters, Lee Ann E Conard, Daniel H Grossoehme
PURPOSE: To quantify HRQOL of TGN patients using the PedsQL 4.0 generic core scales, and to compare reported HRQOL of TGN adolescents with published data from comparison populations. METHODS: Transgender children and adolescents (N = 142; 68% natal females) ages 6-23 years (M = 15.9, SD = 3.7) attending an outpatient clinic for TGN care at an academic pediatric hospital and caregivers of children and adolescents (N = 95) completed the PedsQL 4.0 generic core scales...
March 21, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29535563/gender-dysphoria-in-adolescence-current-perspectives
#7
REVIEW
Riittakerttu Kaltiala-Heino, Hannah Bergman, Marja Työläjärvi, Louise Frisén
Increasing numbers of adolescents are seeking treatment at gender identity services in Western countries. An increasingly accepted treatment model that includes puberty suppression with gonadotropin-releasing hormone analogs starting during the early stages of puberty, cross-sex hormonal treatment starting at ~16 years of age and possibly surgical treatments in legal adulthood, is often indicated for adolescents with childhood gender dysphoria (GD) that intensifies during puberty. However, virtually nothing is known regarding adolescent-onset GD, its progression and factors that influence the completion of the developmental tasks of adolescence among young people with GD and/or transgender identity...
2018: Adolescent Health, Medicine and Therapeutics
https://www.readbyqxmd.com/read/29514975/hormonal-treatment-in-young-people-with-gender-dysphoria-a-systematic-review
#8
REVIEW
Denise Chew, Jemma Anderson, Katrina Williams, Tamara May, Kenneth Pang
CONTEXT: Hormonal interventions are being increasingly used to treat young people with gender dysphoria, but their effects in this population have not been systematically reviewed before. OBJECTIVE: To review evidence for the physical, psychosocial, and cognitive effects of gonadotropin-releasing hormone analogs (GnRHa), gender-affirming hormones, antiandrogens, and progestins on transgender adolescents. DATA SOURCES: We searched Medline, Embase, and PubMed databases from January 1, 1946, to June 10, 2017...
April 2018: Pediatrics
https://www.readbyqxmd.com/read/29504650/the-child-adolescent-bullying-scale-cabs-psychometric-evaluation-of-a-new-measure
#9
Tania D Strout, Judith A Vessey, Rachel L DiFazio, Larry H Ludlow
While youth bullying is a significant public health problem, healthcare providers have been limited in their ability to identify bullied youths due to the lack of a reliable, and valid instrument appropriate for use in clinical settings. We conducted a multisite study to evaluate the psychometric properties of a new 22-item instrument for assessing youths' experiences of being bullied, the Child Adolescent Bullying Scale (CABS). The 20 items summed to produce the measure's score were evaluated here. Diagnostic performance was assessed through evaluation of sensitivity, specificity, predictive values, and area under receiver operating characteristic (AUROC) curve...
March 5, 2018: Research in Nursing & Health
https://www.readbyqxmd.com/read/29503778/transgender-associations-and-possible-etiology-a-literature-review
#10
REVIEW
Fatima Saleem, Syed W Rizvi
Transgender or gender dysphoria has been defined in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), as distress resulting from the incongruence between one's experienced gender and one's assigned gender, along with a persistent and strong desire to be of another gender, and accompanied by clinically significant distress. Adolescents referred for evaluation often want hormonal therapy and several among them also express a desire for gender reassignment surgery. Furthermore, evidence shows that adolescents and adults with gender dysphoria without a sex development disorder, before gender reassignments, are at increased risk for suicide...
December 24, 2017: Curēus
https://www.readbyqxmd.com/read/29503031/attitudes-toward-fertility-and-reproductive-health-among-transgender-and-gender-nonconforming-adolescents
#11
Diane Chen, Margaret Matson, Kathryn Macapagal, Emilie K Johnson, Ilina Rosoklija, Courtney Finlayson, Celia B Fisher, Brian Mustanski
PURPOSE: Little is known about the reproductive desires of transgender and gender-nonconforming (TGNC) adolescents who may seek gender-affirming medical care that leads to infertility. The current study addressed this gap by examining attitudes toward fertility and family formation in a diverse sample of TGNC youth. METHOD: An online survey about sexual/reproductive health in sexual and gender minority (SGM) adolescents ages 14-17 years was conducted from September to October 2016...
March 1, 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29490287/use-of-copper-intrauterine-device-in-transgender-male-adolescents
#12
Sari Bentsianov, Lonna Gordon, Ariella Goldman, Adam Jacobs, John Steever
Transgender men need contraception if engaging in intercourse with a cis-gender male partner. The copper IUD is an effective, non-hormonal contraceptive well suited for trans-males even while utilizing gender affirming hormone therapy. A gender-neutral medical facility with well-trained and sensitive staff is the ideal setting to provide such contraceptive care.
February 25, 2018: Contraception
https://www.readbyqxmd.com/read/29461934/risk-and-protective-factors-for-self-harm-in-a-population-based-sample-of-transgender-youth
#13
Lindsay A Taliaferro, Barbara J McMorris, G Nicole Rider, Marla E Eisenberg
This study sought to identify factors distinguishing transgender/gender non-conforming (GNC) adolescents across three groups: no self-harm, non-suicidal self-injury (NSSI) only, and NSSI and suicide attempt (NSSI +SA). Data were from the 2016 Minnesota Student Survey. The final analytic sample included 1,635 transgender/GNC students in grades 9 and 11. Logistic regression analyses determined factors that best distinguished transgender/GNC students who reported self-harm (NSSI only or NSSI +SA) from those who reported no self-harm, and transgender/GNC adolescents who reported NSSI +SA from those who reported NSSI only...
February 20, 2018: Archives of Suicide Research: Official Journal of the International Academy for Suicide Research
https://www.readbyqxmd.com/read/29455719/community-engagement-and-venue-based-sampling-in-adolescent-male-sexually-transmitted-infection-prevention-research
#14
Mary A Ott, Julianne Campbell, Teresa M Imburgia, Ziyi Yang, Wanzhu Tu, Colette L Auerswald
OBJECTIVES: Middle adolescent males are a difficult group to recruit for community sexually transmitted infection (STI) prevention research. We describe a process of community engagement, and venue-based sampling of 14-17-year-old adolescent males, and compare rates of STIs and STI risk behaviors by venue. METHODS: Community engagement consisted of (1) informational meetings with organizations; (2) participation in community meetings and events; (3) hiring community members as study personnel; and (4) an adolescent advisory board recruited from the community...
March 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29437861/health-and-care-utilization-of-transgender-and-gender-nonconforming-youth-a-population-based-study
#15
G Nicole Rider, Barbara J McMorris, Amy L Gower, Eli Coleman, Marla E Eisenberg
BACKGROUND: Transgender and gender nonconforming (TGNC) adolescents have difficulty accessing and receiving health care compared with cisgender youth, yet research is limited by a reliance on small and nonrepresentative samples. This study's purpose was to examine mental and physical health characteristics and care utilization between youth who are TGNC and cisgender and across perceived gender expressions within the TGNC sample. METHODS: Data came from the 2016 Minnesota Student Survey, which consisted of 80 929 students in ninth and 11th grade ( n = 2168 TGNC, 2...
February 5, 2018: Pediatrics
https://www.readbyqxmd.com/read/29431974/childhood-bullying-implications-for-physicians
#16
Mary M Stephens, Hazel T Cook-Fasano, Katherine Sibbaluca
Childhood bullying is common and can lead to serious adverse physical and mental health effects for both the victim and the bully. In teenagers, risk factors for becoming a victim of bullying include being lesbian, gay, bisexual, or transgender; having a disability or medical condition such as asthma, diabetes mellitus, a skin condition, or food allergy; or being an outlier in weight and stature. An estimated 20% of youth have been bullied on school property, and 16% have been bullied electronically in the past year...
February 1, 2018: American Family Physician
https://www.readbyqxmd.com/read/29425666/early-hormonal-treatment-affects-body-composition-and-body-shape-in-young-transgender-adolescents
#17
Maartje Klaver, Renée de Mutsert, Chantal M Wiepjes, Jos W R Twisk, Martin den Heijer, Joost Rotteveel, Daniël T Klink
BACKGROUND: Transgender adolescents aspiring to have the body characteristics of the affirmed sex can receive hormonal treatment. However, it is unknown how body shape and composition develop during treatment and whether transgender persons obtain the desired body phenotype. AIM: To examine the change in body shape and composition from the start of treatment with gonadotropin-releasing hormone agonists (GnRHa) until 22 years of age and to compare these measurements at 22 years with those of age-matched peers...
February 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29424777/impact-of-insurance-coverage-on-hiv-transmission-potential-among-antiretroviral-therapy-treated-youth-living-with-hiv
#18
Sarah Wood, Sarah Ratcliffe, Charitha Gowda, Susan Lee, Nadia L Dowshen, Robert Gross
OBJECTIVE: To identify the prevalence of high HIV transmission potential in a cohort of youth living with HIV (YLWH), and determine the impact of insurance coverage on potential for HIV transmission. DESIGN: Retrospective cohort study of antiretroviral therapy (ART)-treated YLWH at a US adolescent HIV clinic, 2002-2015. METHODS: The primary exposure was presence or absence of insurance, defined as private, public or pharmacy-only coverage...
February 8, 2018: AIDS
https://www.readbyqxmd.com/read/29343228/problematic-internet-use-and-psychiatric-co-morbidity-in-a-population-of-japanese-adult-psychiatric-patients
#19
Hille T de Vries, Takashi Nakamae, Kenji Fukui, Damiaan Denys, Jin Narumoto
BACKGROUND: Many studies reported the high prevalence of problematic internet use (PIU) among adolescents (13-50%), and PIU was associated with various psychiatric symptoms. In contrast, only a few studies investigated the prevalence among the adult population (6%). This study aimed to investigate the prevalence of PIU and psychiatric co-morbidity among adult psychiatric patients. METHODS: Three hundred thirty-three adult psychiatric patients were recruited over a 3-month period...
January 17, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29315110/stopping-the-rise-of-hiv-among-adolescents-globally
#20
Mary Jane Rotheram-Borus, Emily Davis, Roxana Rezai
PURPOSE OF REVIEW: Adolescents, in particular those that are most disenfranchised, are increasingly at risk of acquiring HIV and, when acquiring HIV, have worse outcomes than adults. This article reviews the recent approaches to combination prevention aiming to optimize the HIV prevention and HIV treatment continua. RECENT FINDINGS: There are dramatic sociodemographic differences in the HIV epidemics in low and middle-income countries (young women in sub-Saharan Africa) compared with high-income countries (predominantly gay, bisexual, transgendered youth, especially black and Latino youth)...
February 2018: Current Opinion in Pediatrics
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