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Che-Wei Hung, Ming-Fang Wu, Gwo-Fane Yu, Chin-Chu Ko, Cheng-Hsing Kao
PURPOSE: To analyze sagittal balance of the cervical spine after three operative methods for three consecutive levels. METHODS: A retrospective case selection and observational study was performed from December 2012 to December 2015: 20 patients underwent anterior cervical discectomy and fusion, 22 patients underwent hybrid surgery (HS), and 20 patients underwent total disc replacement (TDR). Perioperative parameters, clinical outcomes, and preoperative and postoperative sagittal parameters were recorded...
March 9, 2018: Clinical Neurology and Neurosurgery
Davis C Woodworth, Langston T Holly, Emeran A Mayer, Noriko Salamon, Benjamin M Ellingson
BACKGROUND: Advanced cervical spondylosis (CS) can cause structural damage to the spinal cord resulting in long-term neurological impairment including neck pain and motor weakness. We hypothesized long-term structural reorganization within the brain in patients with CS. OBJECTIVE: To explore the associations between cortical thickness, subcortical volumes, neurological symptoms, and pain severity in CS patients with or without myelopathy and healthy controls (HCs)...
March 14, 2018: Neurosurgery
Shinji Horie, Yasunobu Sawaji, Kenji Endo, Hidekazu Suzuki, Yuji Matsuoka, Hirosuke Nishimura, Takeshi Seki, Kengo Yamamoto
INTRODUCTION: Diffuse idiopathic skeletal hyperostosis (DISH) and ossification of the posterior longitudinal ligament (OPLL) are both characterized as ossification in paravertebral ligaments and sometimes present simultaneously, however, the bone metabolism in patients with cervical OPLL accompanying/not accompanying DISH has not well been studied. Thus, a retrospective analysis was performed to understand any differences in bone metabolism in these patients. METHODS: Male patients who underwent surgery for OPLL were divided into two groups based on the presence or absence of DISH (OD and O group, respectively)...
2018: SICOT-J
Erkan Gokce, Murat Beyhan
Objective: The nuchal ligament (NL) extends from the external occipital protuberance and median nuchal line to the spinous process of the 7th cervical vertebrae. In this study, we evaluated the incidence, location level, and size of ossifications of the NL (ONL) in patients who underwent cervical computed tomography (CT) for various reasons. Materials and Methods: The present study included 481 patients (187 females and 294 males) who underwent cervical CT from February 2011 to November 2016 due to reasons such as trauma, cervical spondylosis, neck pain, and screening for metastasis...
February 2018: Eurasian Journal of Medicine
Hiroshi Hagino, Satoshi Soen, Toshitsugu Sugimoto, Naoto Endo, Ryo Okazaki, Kiyoshi Tanaka, Toshitaka Nakamura
We investigated changes in quality of life (QOL), including pain, in Japanese women aged ≥ 55 years who were diagnosed as having osteoporosis at 265 centers across Japan and treated continuously with once-weekly bisphosphonates for 24 months. In 2650 evaluable patients, a significant improvement in QOL was observed from 3 months after enrollment onward and maintained throughout the 2-year observation period. A significant improvement in scores was observed for all domains of the Euro QOL 5 Dimension (EQ-5D), and the "pain", "health perception", and "posture, figure" domains of the Japanese Osteoporosis QOL Questionnaire (JOQOL)...
March 9, 2018: Journal of Bone and Mineral Metabolism
Shih-Yi Lin, Der-Cherng Chen, Cheng-Li Lin, Han-Chung Lee, Tsung-Chih Lin, I-Kuan Wang, Chung-Y Hsu, Chia-Hung Kao
BACKGROUND AND AIMS: Cervical spondylosis (CS) is reported to be associated with increased sympathetic activity and hypertension. However, the cardiovascular (CV) outcomes of patients with CS are largely unknown. METHODS: A national insurance claims dataset of 22 million enrollees in Taiwan during 1999-2010 was used as the research database. We identified 27,948 patients with CS and age-, sex-, and comorbidity-matched controls. By using multivariate logistic regression analysis after adjustment for potential cardiovascular (CV) confounders, we calculated odds ratios (ORs) with 95% confidence intervals (CIs) to quantify the association between CS and acute coronary syndrome (ACS)...
March 1, 2018: Atherosclerosis
Paolo Missori, Maurizio Domenicucci, Daniele Marruzzo
BACKGROUND: Removing the posterior longitudinal ligament in cervical corpectomy is a controversial issue: it is unclear whether the risks are counterbalanced by clinical benefits. Another unexplored topic is whether the width of the corpectomy affects outcome. METHODS: This cross-sectional retrospective study included consecutive patients that underwent cervical corpectomy for spondylosis by 6 different neurosurgeons. We compared two groups, where the posterior longitudinal ligament was either removed (N=15 patients) or preserved (N=21 patients)...
March 3, 2018: World Neurosurgery
Man-Kyu Park, Dae-Chul Cho, Woo-Seok Bang, Kyoung-Tae Kim, Joo-Kyung Sung
PURPOSE: Delayed esophageal perforation after anterior cervical discectomy and fusion (ACDF) is an extremely rare cause of infection such as spondylodiscitis. We present a rare case in which a patient had two delayed esophageal perforations occurring 20 and 25 years after ACDF. By sharing our experience of this rare case, we hope to provide new information related to delayed esophageal perforation. METHODS: We present the case of a 72-year-old patient who underwent ACDF due to cervical spondylosis 25 years ago...
March 2, 2018: European Spine Journal
Jiangbo Bai, Kunlun Yu, Yaning Sun, Lingde Kong, Yong Shen
Background: The aim of this study was to assess the prevalence of cervical Modic change (MC) in patients with cervical spondylosis and to develop a better understanding of the possible risk factors for the prevalence of MC. Methods: Between January 2014 and April 2017, patients with cervical spondylosis were included in our study. All patients underwent magnetic resonance imaging (MRI) to evaluate the presence of MC. The MC was classified into three types according to the Modic classification...
2018: Journal of Pain Research
Aubrey P Monie, Roger I Price, Christopher R P Lind, Kevin P Singer
OBJECTIVES: The purpose of this study was to assess the use of computer-aided combined movement examination (CME) to measure change in low back movement after neurosurgical intervention for lumbar spondylosis and to use a CME normal reference range (NRR) to compare and contrast movement patterns identified from lumbar disk disease, disk protrusion, and nerve root compression cases. METHODS: A test-retest, cohort observational study was conducted. Computer-aided CME was used to record lumbar range of motion in 18 patients, along with pain, stiffness, disability, and health self-report questionnaires...
February 2018: Journal of Manipulative and Physiological Therapeutics
Nathaphon Tangjit, Surachai Dechkunakorn, Niwat Anuwongnukroh, Anuson Khaneungthong, Hathaitip Sritanaudomchai
Background and Objectives: Stem cells from human exfoliated deciduous teeth (SHED) are a promising clinical resource for various tissue defects, including lumbar spondylosis, neural compression, and cleft palate. Use of media containing animal-derived serum carries potential risk of infectious diseases and unwanted immunogenicity. To increase the potential utility of SHED for clinical application, SHED was adapted to xeno-free conditions. Methods: Define xeno-free culture media were compared with the conventional serum containing media in the culture of SHED...
February 28, 2018: International Journal of Stem Cells
Hao-Lin Tan, Cheng Luo, Run Zhang, Zhi-Qing Wang, Hang Ying, Hong-Ting Jin, Pei-Jian Tong, Jin-Min Liu
Esophagustype cervical spondylosis is easily misdiagnosed or missed diagnosed for its lower incidence. The pathological basis manily concerned with compression of osteophyte for esophageal and tracheal wall and local inflammatory reaction. The diagnosis of disease is generally not difficult. Especially dynamic esophagogram could not only show degree of cervical degeneration and osteophyte shape, but also could clearly observe location and degree of osteophytosis indenting esophageal and tracheal. Recently, the treatment of esophagustype cervical spondylosis has been the focus of attention...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
Joseph L Laratta, Jamal N Shillingford, Comron Saifi, K Daniel Riew
Study Design: Systematic review. Objectives: Degenerative disc disease and spondylosis resulting in radiculopathy and retrodiscal myelopathy are among the most frequently encountered cervical spinal disorders. Traditionally, anterior cervical discectomy and fusion (ACDF) has successfully achieved neural decompression and restored intradiscal height in these conditions. Unfortunately, nonunion and iatrogenic adjacent segment pathology associated with fusion procedures in the cervical spine has led to an interest in motion-preserving procedures...
February 2018: Global Spine Journal
Kazuyoshi Kobayashi, Kei Ando, Yoshihiro Nishida, Naoki Ishiguro, Shiro Imagama
PURPOSE: There are few epidemiological studies of spinal surgery in Asia and none in Japan. The goal of this study was to review spine surgeries performed in our group between 2004 and 2015 in a cross-sectional study, with a focus on the effects of the superaging society on the characteristics and trends of spinal surgeries. METHODS: A retrospective review was performed for all 45,831 spinal surgeries conducted between 2004 and 2015 and recorded in our prospective multicenter database...
February 12, 2018: European Spine Journal
Kuan Wang, Zhen Deng, Hui-Hao Wang, Zheng-Yan Li, Wen-Xin Niu, Bo Chen, Ming-Cai Zhang, Wei-An Yuan, Hong-Sheng Zhan
OBJECTIVE: To analyze the relationship between position of head, cervical curvature type and associated cervical balance parameters in a neutral looking-forward posture. METHODS: Cervical lateral X-rays of 60 patients with cervical spondylosis were selected from January to December 2015. There were 22 males and 38 females with an average age of (35.5±10.9) years old. The measured parameters included cervical curvature type, McGregor slope, C2 lower end plate slope, T1 slope, center of gravity to C7 sagittal vertical offset (CG-C7 SVA), and C2 to C7 sagittal vertical offset (C2-C7 SVA)...
May 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
Bu-Qing Chang, Hu Feng, Chao-Jiang Yu, Kai Huang, Xiao Gao, Hao Tang, Yun-Chang Jiang
OBJECTIVE: To compare the short-term efficacy of anterior cervical discectomy and fusion(ACDF) with traditional nail plate system and Zero-profile device in the treatment of cervical spondylotic myelopathy(CSM). METHODS: The clinical data of 45 patients with CSM treated from July 2014 to August 2015 was retrospectively analyzed. There were 23 males and 22 females with an average age of 53.7 years old(range, 32 to 71 years old). The course of disease was 5 months to 2 years...
May 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
Miles O Fortner, Paul A Oakley, Deed E Harrison
[Purpose] To present a case of the non-surgical improvement in cervical kyphosis in a patient with history of cervical spine trauma and advanced osteoarthritis. [Subject and Methods] A 38 year old male presented with a chief complaint of chronic neck pain that was not substantially relieved by recent previous traditional physiotherapy and chiropractic manipulation. The cervical radiograph demonstrated a cervical hypolordosis of 5° as measured by the Harrison posterior tangent method from C2-C7. There was a 15° kyphosis at C4-C6 with advanced degenerative changes consistent with previous spine trauma...
January 2018: Journal of Physical Therapy Science
Jad N Bou Monsef, Krzysztof B Siemionow
Context: Cervical spondylotic myelopathy (CSM) is a progressive disease that can result in significant disability. Single-level stenosis can be effectively decompressed through either anterior or posterior techniques. However, multilevel pathology can be challenging, especially in the presence of significant spinal stenosis. Three-level anterior decompression and fusion are associated with higher nonunion rates and prolonged dysphagia. Posterior multilevel laminectomies with foraminotomies jeopardize the bone stock required for stable fixation with lateral mass screws (LMSs)...
October 2017: Journal of Craniovertebral Junction and Spine
Ziqiang Wang, Liangliang Zhou, Bin Lin, Keran Song, Qinghe Niu, Dongfeng Ren, Jiaguang Tang
BACKGROUND: The purpose of this study was to investigate the incidence and causes of non-fusion segment disease (NFSD), both adjacent and non-adjacent to a fused segment, after anterior cervical arthrodesis. METHODS: This is a single-center study. Between January 1998 and January 2011, two surgeons' 171 patients who had an anterior cervical decompression and fusion were followed clinically for more than 5 years. The correlation between the incidence of symptomatic non-fusion segment disease and the following clinical parameters (age at operation, fusion levels,) and radiological parameters (number of patients who had a plate, anterior cervical decompression and fusion (ACDF) or corpectomies, preoperative and postoperative cervical spine alignment, Pavlov's ratio at the C5 level, and preoperative existence of a non-fusion segment degeneration on magnetic resonance imaging) was evaluated...
February 2, 2018: Journal of Orthopaedic Surgery and Research
Anita Bhansali, Michael Musacchio, Noam Stadlan
Cervical disc arthroplasty (CDA) has emerged as a popular alternative to anterior cervical discectomy and fusion (ACDF) for the surgical treatment of cervical degenerative disc disease. CDA has been well studied, with efficacy reported to be equivalent to or better than that seen with ACDF, and it is associated with a consistently low incidence of adverse events. The development or progression of myelopathy after CDA is a particularly rare occurrence. In this report, the authors describe the first known case of recurrence of myelopathy at the index level of surgery after CDA implantation due the continuation of the spondylitic process after placement of the artificial disc...
February 2, 2018: Journal of Neurosurgery. Spine
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