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Spondylosis

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https://www.readbyqxmd.com/read/28629570/the-association-between-multiple-sclerosis-and-spondylosis-when-and-why
#1
Vasileios G Xydis, Anastasia K Zikou, Vassiliki Kostadima, Loukas G Astrakas, Paraskevi Kosta, Maria I Argyropoulou
OBJECTIVES: To evaluate risk factors for the development of cervical spine spondylosis (CSS) in patients with multiple sclerosis (MS) and to propose a pathogenetic mechanism. METHODS: Forty-two consecutive patients aged 23-66 years with MS and 42 age and sex matched controls were evaluated retrospectively; Clinical disability was evaluated with the expanded disability status scale (EDSS) and spasticity with the Asworth score. Total brain lesion volume (BLV), total grey matter (GM) volume and deep GM volume were assessed...
June 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28598113/-effects-of-huoxue-dingxuan-capsule-glare-on-vertebral-artery-blood-flow-plasma-pai-and-t-pa-in-csa-rat-models
#2
Qing-Lin Li, Min Song, Ding-Ping Sun, Bin-Xiao Sun, Tao Liu, Yan-Long Gong, Ju-Tang Chai, Xiao Liu
OBJECTIVES: To determine the effects of Huoxue Dingxuan Capsule on vertebral artery blood flow,plasma plasminogen activator (t-PA) and plasminogen activator inhibitor (PAI) in rats with cervical spondylosis of vertebral artery type (CSA). METHODS: Ninety healthy male Wistar rats were equally and randomly divided into control,model and treatment groups.The rats in the model and treatment groups were subject to composite modeling manufacturing CSA.The treatment group was given six-week interventions with Huoxue Dingxuan capsule 4 weeks after the modeling...
November 2016: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28591077/progressive-bone-formation-after-cervical-disc-replacement-minimum-of-5-year-follow-up
#3
Feifei Zhou, Kevin L Ju, Yanbin Zhao, Fengshan Zhang, Shengfa Pan, John G Heller, Yu Sun
OBJECTIVE: Our objective was to examine the prevalence, clinical significance, ramifications, and possible etiology of postoperative bone formation at the index level after Cervical Disc Replacement (CDR) with a minimum of five years of follow-up. SUMMARY OF BACKGROUND DATA: CDR can be complicated by postoperative ossification and unwanted ankylosis at the index level, which some authors have termed "heterotopic ossification". This terminology may be inaccurate as it assumes the postoperative bone formation is unnatural and a consequence of the CDR surgery...
June 6, 2017: Spine
https://www.readbyqxmd.com/read/28587505/chronic-cervical-radiculopathic-pain-is-associated-with-increased-excitability-and-hyperpolarization-activated-current-ih-in-large-diameter-dorsal-root-ganglion-neurons
#4
Da-Lu Liu, Xu Wang, Wen-Guang Chu, Na Lu, Wen-Juan Han, Yi-Kang Du, San-Jue Hu, Zhan-Tao Bai, Sheng-Xi Wu, Rou-Gang Xie, Ceng Luo
Cervical radiculopathic pain is a very common symptom that may occur with cervical spondylosis. Mechanical allodynia is often associated with cervical radiculopathic pain and is inadequately treated with current therapies. However, the precise mechanisms underlying cervical radiculopathic pain-associated mechanical allodynia have remained elusive. Compelling evidence from animal models suggests a role of large-diameter dorsal root ganglion neurons and plasticity of spinal circuitry attached with Aβ fibers in mediating neuropathic pain...
January 2017: Molecular Pain
https://www.readbyqxmd.com/read/28582838/the-effect-of-gigantomasty-on-vertebral-degeneration-a-computed-tomography-study
#5
Bekir Sanal, Mehmet Korkmaz, Omer Fatih Nas, Fatma Can, Kadir Hacikurt
The main reason for waist and back pain in patients with gigantomasty is increased thoracic kyphosis and lumber lordosis. These symptoms and abnormal spinal angulations regress after reduction mammoplasty operations. However, the effect of chronic mechanical stress caused by gigantomasty on the spinal degenerative process is not clear yet. In this study with computed tomography it is shown that degenerative spondylosis is more widespread and severe in patients with large breasts.
May 12, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28580360/complete-cranial-iliac-osteotomy-to-approach-the-lumbosacral-foramen
#6
Barbara Dyall, Hugo Schmökel
An approach using a complete cranial iliac osteotomy (CCIO) to access the lumbosacral (LS) foramen in dogs from lateral was developed using cadavers and applied in a clinical patient with degenerative lumbosacral stenosis (DLSS). The foraminal enlargement in the cadavers and the patient was documented on postoperative CT scans. The preoperative CT scan of the patient showed moderate cranial telescoping of the sacral roof and a moderate central disk protrusion, leading to moderate to severe compression of the cauda equina...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28572225/an-unusual-case-of-orthopnea
#7
Emma Keelan, Joseph Kidney, Eoin P Judge
Bilateral diaphragmatic paralysis is a known cause of respiratory failure. Diagnosis can be difficult, particularly in the acute setting. We present the case of a gentleman diagnosed with bilateral diaphragmatic paralysis secondary to phrenic neuropathy in the setting of cervical spondylosis.
June 2017: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/28540118/spinal-cord-injury-in-the-geriatric-population-risk-factors-treatment-options-and-long-term-management
#8
REVIEW
Tochukwu C Ikpeze, Addisu Mesfin
Spinal cord injuries (SCIs) are sustained by more than 12 500 patients per year in the United States and more globally. The SCIs disproportionately affect the elderly, especially men. Approximately 60% of these injuries are sustained traumatically through falls, but nontraumatic causes including infections, tumors, and medication-related epidural bleeding have also been documented. Preexisting conditions such as ankylosing spondylitis and diffuse idiopathic skeletal hyperostosis can render the spine stiff and are risk factors as well as cervical spondylosis and ensuing cervical stenosis...
June 2017: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/28525486/regression-of-anterior-disk-osteophyte-complex-following-cervical-laminectomy-and-fusion-for-cervical-spondylotic-myelopathy
#9
Adedayo O Ashana, Jeremiah R Cohen, Brandon Evans, Langston T Holly
STUDY DESIGN: A retrospective case-control study. OBJECTIVE: To investigate whether posterior cervical laminectomy and fusion modifies the natural course of anterior disk-osteophyte complex in patients with multilevel cervical spondylotic myelopathy. SUMMARY OF BACKGROUND DATA: Dorsal migration of the spinal cord is the main purported mechanism of spinal cord decompression following cervical laminectomy and fusion but other potential mechanisms have received scant attention in the literature...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28525469/safety-and-efficacy-study-of-an-ozone-laser-combined-therapy-using-puncture-needle-in-the-treatment-of-patients-with-cervical-spondylosis
#10
Ke Gu, Yuqiu Yan, Wu Wei, Yan Li, Wenli Liu, Yang Guo, Long Yu
STUDY DESIGN AND METHODS: Fifty-eight patients with cervical spondylosis (CS) were treated with patented technology of ozone laser combined therapy using puncture needle between August 2008 and February 2010. Visual Analogue Scale (VAS) score changes before and 6 months after surgery and MacNab score criteria 6 months after surgery were analyzed. BACKGROUND AND OBJECTIVE: CS normally occurs over the age of 50 and broadly presents as either myelopathy or radiculopathy...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28508239/double-crush-syndrome-caused-by-cervical-spondylosis-and-vertebral-artery-loop
#11
Young Joon Rho, Woo Jin Choe
PURPOSE: The purpose of this article is to report a successful treatment experience in a rare case of simultaneous cervical nerve root compression by spondylotic cervical foraminal stenosis and a vertebral artery loop. METHODS: 51-year-old man presented with a 4-year history of left-sided cervical pain radiating to the left shoulder with progressive exacerbation of weakness on left shoulder girdle muscles for 7 months. The patient had no history of trauma. The patient's CT and MRI revealed impingement of the left C6 cervical nerve root by a tortuous vertebral artery loop and also by narrowed left C5-6 cervical foramen that had undergone spondylotic changes...
May 15, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28507882/aquaporin-1-expression-in-herniated-human-lumbar-intervertebral-discs
#12
Haydn Hoffman, Aaron W Choi, Victor Chang, Jon Kimball, Alan S Verkman, Rubeen Virani, Brian Kim, Tianyi Niu, Daniel C Lu
STUDY DESIGN: Case series. OBJECTIVE: Intervertebral disc (IVD) degeneration is the cause of spondylosis. The pathogenesis is poorly understood, but disc dehydration often plays a role. In this study, we aim to identify and quantify aquaporin-1 (AQP1) in ex vivo human degenerated IVDs obtained intraoperatively and to investigate the relationship between AQP1 levels and magnetic resonance imaging (MRI) T2 intensity of the disc. METHODS: Ex vivo samples of nucleus pulposus (NP) tissue from lumbar IVDs were obtained from 18 consecutive patients who underwent surgery for disc herniation at L4/5 and L5/S1 level...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28491215/clinical-outcomes-of-posterior-spinal-stabilization-with-rigid-vertical-strut-and-spinal-process-wires-the-adeolu-s-technique-in-a-developing-country
#13
Taopheeq Bamidele Rabiu
INTRODUCTION: Conventional instrumentation for spinal stabilization is beyond the reach of many patients in developing countries. A low-cost and easily-available method of spinal stabilization using vertical struts and spinal process wires (Adeolu's technique) was recently introduced in Nigeria. We describe the clinical outcomes of a prospective series of patients managed using the technique. METHODS: From 2011 to 2012, we performed posterior spinal stabilization in eighteen patients using the technique...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28461958/management-of-degenerative-lumbar-spinal-stenosis-an-evidence-based-review
#14
REVIEW
Augusto Covaro, Gemma Vilà-Canet, Ana García de Frutos, Maite T Ubierna, Francesco Ciccolo, Enric Caceres
Lumbar spinal stenosis has become one of the most disabling pathologies in the elderly population.Some additional conditions such as foraminal stenosis or degenerative spondylosis with a history of back pain and leg pain must be considered before treatment.A completely appropriate protocol and unified management of spinal stenosis have not yet been well defined.The objective of this literature review is to provide evidence-based recommendations reflected in the highest-quality clinical literature available to address key clinical questions surrounding the management of degenerative lumbar spinal stenosis...
July 2016: EFORT open reviews
https://www.readbyqxmd.com/read/28443160/correlation-between-preoperative-magnetic-resonance-imaging-signal-intensity-changes-and-clinical-outcomes-in-patients-surgically-treated-for-cervical-myeloradiculopathy
#15
Chaitanya Baban Chikhale, Ketan Shripad Khurjekar, Ashok Kumar Shyam, Parag Kantilal Sancheti
STUDY DESIGN: This was a single surgeon, single center-based retrospective study with prospective data collection. PURPOSE: To assess the correlation between T2-weighted magnetic resonance imaging (MRI) signal intensity (SI) changes and factors such as age, duration of symptoms, baseline modified Japanese Orthopedic Association (mJOA) score and to determine its prognostic value in predicting recovery after surgery. OVERVIEW OF LITERATURE: Whether intramedullary cord T2-weighted MRI SI changes can predict operative outcomes of cervical myeloradiculopathy remains debatable, with only a few prospective studies analyzing the same...
April 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28441681/complications-and-mortality-following-one-to-two-level-anterior-cervical-fusion-for-cervical-spondylosis-in-patients-above-80-years-of-age
#16
Varun Puvanesarajah, Amit Jain, Adam L Shimer, Anuj Singla, Francis Shen, Hamid Hassanzadeh
STUDY DESIGN: A retrospective database review. OBJECTIVE: The aim of this study was to determine the complication and mortality rates in patients 80 years of age and older who were treated with anterior cervical fusion surgery and to compare these rates against those of other elderly patients. SUMMARY OF BACKGROUND DATA: Cervical spondylosis is frequently observed in the elderly and is the most common cause of myelopathy in older adults. With increasing life expectancies, a greater proportion of patients are being treated with spine surgery at a later age...
May 1, 2017: Spine
https://www.readbyqxmd.com/read/28413581/robotic-assisted-inferior-vena-cava-filter-retrieval
#17
Shahin Owji, Tony Lu, Thomas M Loh, Adeline Schwein, Alan B Lumsden, Jean Bismuth
Although anticoagulation remains the mainstay of therapy for patients with venous thromboembolism, guidelines recommend the use of inferior vena cava (IVC) filters in those who fail anticoagulation or have contraindications to its use. Short-term use of filters has proven effective in reducing the rate of pulmonary embolism. However, their extended use is associated with a variety of complications such as thrombosis, filter migration, or caval perforation, thus making a case for timely filter retrieval. This is the case of a 68-year-old female with a history of chronic oral anticoagulation use for multiple deep venous thrombi (DVT) and pulmonary emboli (PE) who required cervical and thoracic spinal intervention for spondylosis and foramina stenosis...
January 2017: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/28413117/structure-specific-movement-patterns-in-patients-with-chronic-low-back-dysfunction-using-lumbar-combined-movement-examination
#18
Aubrey P Monie, Roger I Price, Christopher R P Lind, Kevin P Singer
OBJECTIVE: A test-retest cohort study was conducted to assess the use of a novel computer-aided, combined movement examination (CME) to measure change in low back movement after pain management intervention in 17 cases of lumbar spondylosis. Additionally we desired to use a CME normal reference range (NRR) to compare and contrast movement patterns identified from 3 specific structural pathologic conditions: intervertebral disc, facet joint, and nerve root compression. METHODS: Computer-aided CME was used before and after intervention, in a cohort study design, to record lumbar range of movement along with pain, disability, and health self-report questionnaires in 17 participants who received image-guided facet, epidural, and/or rhizotomy intervention...
April 13, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28402458/the-influence-of-pelvic-incidence-and-lumbar-lordosis-mismatch-on-development-of-symptomatic-adjacent-level-disease-following-single-level-transforaminal-lumbar-interbody-fusion
#19
Zachary J Tempel, Gurpreet S Gandhoke, Bryan D Bolinger, Nicolas K Khattar, Philip V Parry, Yue-Fang Chang, David O Okonkwo, Adam S Kanter
BACKGROUND: Annual incidence of symptomatic adjacent level disease (ALD) following lumbar fusion surgery ranges from 0.6% to 3.9% per year. Sagittal malalignment may contribute to the development of ALD. OBJECTIVE: To describe the relationship between pelvic incidence-lumbar lordosis (PI-LL) mismatch and the development of symptomatic ALD requiring revision surgery following single-level transforaminal lumbar interbody fusion for degenerative lumbar spondylosis and/or low-grade spondylolisthesis...
June 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28382238/evaluation-and-interventional-management-of-pain-after-vertebral-augmentation-procedures
#20
Jesse Hatgis, Michelle Granville, Robert E Jacobson
INTRODUCTION: A small subset of patients who underwent successful vertebral compression fracture (VCF) augmentation procedures may develop subsequent pain requiring spinal injections. In a retrospective analysis, we determined whether the pain was related to the original fracture site or to another area within the lumbar or thoracic spine. The pain occurred either at the same/adjacent level and/or non-adjacent level as the VCF. Interventional treatments primarily targeted the facet joints, specifically in the form of facet joint blocks and/or radiofrequency ablation to the medial branches...
February 28, 2017: Curēus
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