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Dialysis and exercise

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https://www.readbyqxmd.com/read/29233322/using-simplistic-simulations-to-enhance-learning-in-a-nephrology-pharmacotherapeutics-module
#1
Yen H Dang
BACKGROUND AND PURPOSE: The purpose of this study was to evaluate the effect of a simplistic simulation exercise in a nephrology module on pharmacy students' learning in a three-year concentrated curriculum. EDUCATIONAL ACTIVITY AND SETTING: Second year pharmacy students participated in a two-part simulation on electrolyte imbalances and dialysis in a nephrology pharmacotherapeutics module. Students completed a seven-item anonymous survey at the end of the simulation on a five-point Likert scale to examine the effect of the simulation and their attitudes to the exercise...
September 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29228710/irisin-treatment-improves-healing-of-dystrophic-skeletal-muscle
#2
Musarrat Maisha Reza, Chu Ming Sim, Nathiya Subramaniyam, Xiaojia Ge, Mridula Sharma, Ravi Kambadur, Craig McFarlane
Background: Irisin is an exercise induced myokine that is shown to promote browning of adipose tissue and hence, increase energy expenditure. Furthermore, our unpublished results indicate that Irisin improves myogenic differentiation and induces skeletal muscle hypertrophy. Since exercise induced skeletal muscle hypertrophy improves muscle strength, we wanted to investigate if ectopic injection of Irisin peptide improves skeletal muscle function in a mouse model of muscular dystrophy...
November 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29222290/chronic-organ-failure-in-adult-sickle-cell-disease
#3
REVIEW
Elliott Vichinsky
Sickle cell disease is now a chronic adult illness characterized by progressive multiorgan failure, particularly involving the brain and kidney. The etiology is multifactorial; it includes hemolysis and nitric oxide deficiency. As patients age, most experience neurologic insult. Twenty-five percent of older adults have had a clinical stroke and at least half of the population have had a silent infarct, cortical atrophy, and neurocognitive impairment. Periodic screening with neuroimaging and neurocognitive testing is recommended...
December 8, 2017: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/29203397/pro-arrhythmic-effects-of-low-plasma-k-in-human-ventricle-an-illustrated-review
#4
REVIEW
Beatriz Trenor, Karen Cardona, Lucia Romero, Juan F Gomez, Javier Saiz, Sridharan Rajamani, Luiz Belardinelli, Wayne Giles
Potassium levels in the plasma, [K+]o, are regulated precisely under physiological conditions. However, increases (from approx. 4.5 to 8.0mM) can occur as a consequence of, e.g., endurance exercise, ischemic insult or kidney failure. This hyperkalemic modulation of ventricular electrophysiology has been studied extensively. Hypokalemia is also common. It can occur in response to diuretic therapy, following renal dialysis, or during recovery from endurance exercise. In the human ventricle, clinical hypokalemia (e...
November 24, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29199185/efficacy-and-safety-of-whole-body-vibration-in-maintenance-hemodialysis-patients-a-pilot-study
#5
L Seefried, F Genest, N Luksche, M Schneider, G Fazeli, M Brandl, U Bahner, A A Heidland
OBJECTIVES: The aim of this study was to assess safety and effectiveness of Whole Body Vibration exercise (WBV) to improve physical performance and parameters of inflammation in patients on maintenance hemodialysis (MHD). METHODS: Prospective, open-label trial in n=14 patients on maintenance hemodialysis. Participants performed WBV twice weekly for 12 weeks before (n=8) or after (n=6) hemodialysis sessions. The primary endpoint was physical performance assessed by the Short-Physical-Performance-Battery (SPPB)...
December 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/29165174/the-joint-impact-of-habitual-exercise-and-glycemic-control-on-the-incidence-of-chronic-kidney-disease-ckd-in-middle-aged-and-older-males
#6
Ryoma Michishita, Takuro Matsuda, Shotaro Kawakami, Satoshi Tanaka, Akira Kiyonaga, Hiroaki Tanaka, Natsumi Morito, Yasuki Higaki
BACKGROUND: This retrospective study evaluated the influence of the joint impact of habitual exercise and glycemic control on the incidence of chronic kidney disease (CKD) during a 6-year follow-up period in middle-aged and older males. METHODS: The study population included 303 males without a history of cardiovascular disease, stroke, renal dysfunction, or dialysis treatment. Their lifestyle behaviors regarding exercise and physical activity were evaluated using a standardized self-administered questionnaire...
November 6, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29017151/the-clinical-significance-of-physical-activity-in-maintenance-dialysis-patients
#7
Seok Hui Kang, Jun Young Do, Hye Yun Jeong, So-Young Lee, Jun Chul Kim
BACKGROUND: The aim of the present study was to evaluate the effects of physical activity on various aspects in Asian dialysis patients. METHODS: This was a retrospective cohort study. Study participants were recruited from 27 hospitals or dialysis centers in Korea (n = 1611). The participants were divided into 3 groups according to the degree of regular exercise: Inactive group, Intermediate group, and Active group. RESULTS: The proportions of patients with frailty and the presence of each component decreased as physical activity increased...
2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/28993865/two-year-cortical-and-trabecular-bone-loss-in-ckd-5d-biochemical-and-clinical-predictors
#8
H H Malluche, M-C Monier-Faugere, G Blomquist, D L Davenport
This prospective two-year study of patients on chronic dialysis measured changes in bone mineral density (BMD). Patients with higher baseline BMD and shorter dialysis vintage lost more bone. Treatment with anti-hypertensives acting on the central nervous system was protective against bone loss. Baseline serum levels of sclerostin and bone-specific alkaline phosphatase predicted bone loss. INTRODUCTION: This prospective 2-year study of chronic kidney disease on dialysis (CKD-5D) patients assessed trabecular and cortical bone loss at the hip and spine and examined potential demographic, clinical, and serum biochemical predictors of bone loss...
October 9, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28979783/obesity-and-listing-for-renal-transplantation-weighing-the-evidence-for-a-growing-problem
#9
Mohammed Hossain, Alexander Woywodt, Titus Augustine, Videha Sharma
A 56-year-old female patient was referred to the transplant assessment clinic in July 2016. She started haemodialysis in 2012 for renal failure due to urinary tract infections. She is doing very well on dialysis and has an excellent exercise tolerance without shortness of breath or angina. She has had no infections since starting dialysis and no other comorbidity, except well-controlled hypertension and hyperparathyroidism requiring treatment with cinacalcet. Clinical examination is essentially normal except for truncal obesity with height 167 cm and weight 121 kg, giving her a body mass index of 43...
October 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/28970364/physical-function-and-physical-activity-in-peritoneal-dialysis-patients
#10
Patricia Painter, Adhish Agarwal, Micah Drummond
BACKGROUND: Physical functioning (PF) and physical activity (PA) are low in patients treated with maintenance hemodialysis (MHD). Little information exists on this topic in patients treated with peritoneal dialysis (PD). The objective of this study was to compare PF and PA in patients with Stage-5 chronic kidney disease (CKD) treated with PD and in-center MHD. METHODS: Physical functioning was measured in 45 prevalent PD patients using standard physical performance measures that include gait speed, chair stand, standing balance, 6-minute-walk, incremental shuttle walk and self-reported PF using the short form (SF)-36 questionnaire...
September 28, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/28961405/impact-of-intradialytic-exercise-intensity-on-urea-clearance-in-hemodialysis-patients
#11
Paul David Stuart Brown, Kylie Rowed, Jane Shearer, Jennifer M MacRae, Kristen Parker
Intradialytic exercise (IDE) has been shown to benefit dialysis efficacy; however, the effect of IDE intensity is unknown. Dialyzer urea clearance (K urea, ml/min) was significantly greater during both IDE protocols (55% and 70% maximal heart rate, HRmax), compared to no IDE (p<0.05). No significant difference in K urea was found between IDE protocols (55% vs. 70% HRmax) (p>0.05). Results show that higher intensity IDE has no additional benefit on K urea.
September 29, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28893206/efficacy-of-blood-flow-restriction-exercise-during-dialysis-for-end-stage-kidney-disease-patients-protocol-of-a-randomised-controlled-trial
#12
Matthew J Clarkson, Steve F Fraser, Paul N Bennett, Lawrence P McMahon, Catherine Brumby, Stuart A Warmington
BACKGROUND: Exercise during haemodialysis improves strength and physical function. However, both patients and clinicians are time poor, and current exercise recommendations add an excessive time burden making exercise a rare addition to standard care. Hypothetically, blood flow restriction exercise performed during haemodialysis can provide greater value for time spent exercising, reducing this time burden while producing similar or greater outcomes. This study will explore the efficacy of blood flow restriction exercise for enhancing strength and physical function among haemodialysis patients...
September 11, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28891419/effects-of-listening-to-holy-qur-an-recitation-and-physical-training-on-dialysis-efficacy-functional-capacity-and-psychosocial-outcomes-in-elderly-patients-undergoing-haemodialysis
#13
Bechir Frih, Wajdi Mkacher, Abir Bouzguenda, Hamdi Jaafar, Salem Ali ALkandari, Zohra Ben Salah, Bart Sas, Mohamed Hammami, Ameur Frih
The purpose of this study was to determine whether listening to Holy Qur'an recitation would augment the beneficial effects of physical exercise on physiological and psychological measures in elderly patients undergoing haemodialysis. Fifty-three male haemodialysis patients were randomly assigned to an intervention group (listening to Holy Qur'an recitation in combination with endurance-resistance training, n = 28) or a control group (endurance-resistance training only, n = 25). Functional capacity was assessed using the Timed Up and Go test (TUG) and the Six-Minute Walk Test (6MWT)...
December 2017: Libyan Journal of Medicine
https://www.readbyqxmd.com/read/28887058/does-resistance-exercise-performed-during-dialysis-modulate-nrf2-and-nf-%C3%AE%C2%BAb-in-patients-with-chronic-kidney-disease
#14
RANDOMIZED CONTROLLED TRIAL
C C Abreu, L F M F Cardozo, M B Stockler-Pinto, M Esgalhado, J E Barboza, R Frauches, D Mafra
Studies have shown that nuclear factor erythroid 2-related factor 2 (Nrf2) can be modulated by physical exercise. However, the impact of resistance exercise has never been investigated in patients with chronic kidney disease (CKD). The aim of this study was to evaluate the effects of resistance exercise programs on the expression of transcription factors Nrf2 and nuclear factor κB (NF-κB) in CKD patients on hemodialysis (HD). Patients on an HD program were randomly assigned to an exercise group of 25 patients (54...
November 1, 2017: Life Sciences
https://www.readbyqxmd.com/read/28852491/captivating-a-captive-audience-a-quality-improvement-project-increasing-participation-in-intradialytic-exercise-across-five-renal-dialysis-units
#15
Lyndsey Abdulnassir, Sara Egas-Kitchener, Daniel Whibley, Tom Fynmore, Gareth D Jones
BACKGROUND: Benefits of exercise on dialysis (EOD) are well established, however, uptake in our local satellite haemodialysis units is low. The implications of the status quo are risks to treatment efficiency, equity and patient centredness in managing personal health risks. The current study aimed to identify and address barriers to exercise participation while on dialysis by substantiating local EOD risks, assigning context, implementing changes and evaluating their impact. Our primary objective was to increase the uptake of EOD across our five dialysis units...
August 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/28838226/intradialytic-exercise-improves-physical-function-and-reduces-intradialytic-hypotension-and-depression-in-hemodialysis-patients
#16
So Yon Rhee, Jin Kyung Song, Suk Chul Hong, Jae Won Choi, Hee Jung Jeon, Dong Ho Shin, Eun Hee Ji, Eun-Hee Choi, Jiyeon Lee, Aram Kim, Seung Wook Choi, Jieun Oh
Background/Aims: As numbers of maintenance hemodialysis patients are growing, debilitating conditions of muscle wasting and atrophy are becoming some of the greatest concerns in end-stage renal disease patients. Exercise training has various potential benefits in terms of prevention of a sustained decline in functional status. This study aimed to evaluate the physical, psychological, laboratory, and dialysis-related effects of intradialytic exercise. Methods: We enrolled 22 patients from a hemodialysis center for a 6-month non-randomized prospective trial...
August 25, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28795012/chronic-kidney-disease-and-sports-participation-by-children-and-adolescents
#17
REVIEW
Vimal Master Sankar Raj, Dilip R Patel, Lakshmi Ramachandran
Individuals suffering from chronic kidney disease (CKD) deal with major morbidity and mortality including poor exercise tolerance. A variety of factors including anemia, poor muscle mass, cardiovascular changes and limited physical activity contribute to exercise intolerance. Studies suggest that early initiation of aerobic and resistance training improves the muscle function, ability to tolerate exercise and quality of life in CKD patients. A thorough medical examination and exercise testing are recommended before initiating an exercise regimen in individuals with CKD...
July 2017: Translational Pediatrics
https://www.readbyqxmd.com/read/28643119/home-based-versus-center-based-aerobic-exercise-on-cardiopulmonary-performance-physical-function-quality-of-life-and-quality-of-sleep-of-overweight-patients-with-chronic-kidney-disease
#18
Danilo Takashi Aoike, Flavia Baria, Maria Ayako Kamimura, Adriano Ammirati, Lilian Cuppari
BACKGROUND: The association between chronic kidney disease (CKD) and obesity can decrease the patients' cardiopulmonary capacity, physical functioning and quality of life. The search for effective and practical alternative methods of exercise to engage patients in training programs is of great importance. Therefore, we aimed to compare the effects of home-based versus center-based aerobic exercise on the cardiopulmonary and functional capacities, quality of life and quality of sleep of overweight non-dialysis-dependent patients with CKD (NDD-CKD)...
June 22, 2017: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/28623895/effects-of-home-based-exercise-on-pre-dialysis-chronic-kidney-disease-patients-a-randomized-pilot-and-feasibility-trial
#19
Koji Hiraki, Yugo Shibagaki, Kazuhiro P Izawa, Chiharu Hotta, Akiko Wakamiya, Tsutomu Sakurada, Takashi Yasuda, Kenjiro Kimura
BACKGROUND: Only a few research is available on the effects of home-based exercise training on pre-dialysis chronic kidney disease (CKD) patients. Therefore, we aimed to elucidate the effect of home-based exercise therapy on kidney function and arm and leg muscle strength in pre-dialysis CKD patients. METHODS: Thirty-six male stage 3-4 pre-dialysis CKD patients (age, 68.7 ± 6.8 years; estimated glomerular filtration rate (eGFR), 39.0 ± 11.6 ml/min/1.73 m(2)) who were being treated as outpatients were included...
June 17, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28620308/the-effect-of-interdialytic-combined-resistance-and-aerobic-exercise-training-on-health-related-outcomes-in-chronic-hemodialysis-patients-the-tunisian-randomized-controlled-study
#20
Bechir Frih, Hamdi Jaafar, Wajdi Mkacher, Zohra Ben Salah, Mohamed Hammami, Ameur Frih
Background: Tunisia has the highest prevalence of hemodialysis patients compared to the other countries in North Africa. Dialysis centers rarely offer an exercise program to prevent physiological and psychological dialysis therapy-related alterations in chronic hemodialysis patients. Aim: To examine the effect of combined endurance-resistance training program on physiological and psychological outcomes in patients undergoing hemodialysis. Methods: We designed a single blinded, randomized, controlled study for a period of 4 months...
2017: Frontiers in Physiology
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