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https://www.readbyqxmd.com/read/29468152/negative-thermal-expansion-over-a-wide-temperature-range-in-fe-doped-mnnige-composites
#1
Wenjun Zhao, Ying Sun, Yufei Liu, Kewen Shi, Huiqing Lu, Ping Song, Lei Wang, Huimin Han, Xiuliang Yuan, Cong Wang
Fe-doped MnNiGe alloys were successfully synthesized by solid-state reaction. Giant negative thermal expansion (NTE) behaviors with the coefficients of thermal expansion (CTE) of -285.23 × 10-6 K-1 (192-305 K) and -1167.09 × 10-6 K-1 (246-305 K) have been obtained in Mn0.90 Fe0.10 NiGe and MnNi0.90 Fe0.10 Ge, respectively. Furthermore, these materials were combined with Cu in order to control the NTE properties. The results indicate that the absolute value of CTE gradually decreases with increasing Cu contents...
2018: Frontiers in Chemistry
https://www.readbyqxmd.com/read/29465327/improving-the-translational-potential-of-rodent-models-to-study-the-behavioral-and-pathophysiological-effects-of-repetitive-mild-traumatic-brain-injury
#2
Megan Elizabeth Huibregtse
Chronic traumatic encephalopathy (CTE) is thought to be caused by repetitive head impacts. Consequently, there is a need to develop rodent models to better understand the behavioral and pathophysiological changes of repetitive mild traumatic brain injury (rmTBI) and to determine the link between rmTBI and CTE. This Neuro Forum article reviews recent rodent rmTBI models, comparing the impact methods and outcome measures in terms of translational potential.
February 21, 2018: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29458610/warpage-characteristics-and-process-development-of-through-silicon-via-less-interconnection-technology
#3
Wen-Wei Shen, Yu-Min Lin, Sheng-Tsai Wu, Chia-Hsin Lee, Shin-Yi Huang, Hsiang-Hung Chang, Tao-Chih Chang, Kuan-Neng Chen
In this study, through silicon via (TSV)-less interconnection using the fan-out wafer-level-packaging (FO-WLP) technology and a novel redistribution layer (RDL)-first wafer level packaging are investigated. Since warpage of molded wafer is a critical issue and needs to be optimized for process integration, the evaluation of the warpage issue on a 12-inch wafer using finite element analysis (FEA) at various parameters is presented. Related parameters include geometric dimension (such as chip size, chip number, chip thickness, and mold thickness), materials' selection and structure optimization...
August 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29430480/further-characterization-of-changes-in-axial-strain-elastograms-due-to-the-presence-of-slippery-tumor-boundaries
#4
Christopher Uff, Leo Garcia, Jeremie Fromageau, Aabir Chakraborty, Neil Dorward, Jeffrey Bamber
Elastography measures tissue strain, which can be interpreted under certain simplifying assumptions to be representative of the underlying stiffness distribution. This is useful in cancer diagnosis where tumors tend to have a different stiffness to healthy tissue and has also shown potential to provide indication of the degree of bonding at tumor-tissue boundaries, which is clinically useful because of its dependence on tumor pathology. We consider the changes in axial strain for the case of a symmetrical model undergoing uniaxial compression, studied by characterizing changes in tumor contrast transfer efficiency (CTE), inclusion to background strain contrast and strain contrast generated by slip motion, as a function of Young's modulus contrast and applied strain...
April 2018: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29421973/multimodal-characterization-of-the-late-effects-of-tbi-letbi-a-methodological-overview-of-the-letbi-project
#5
Brian L Edlow, C Dirk Keene, Daniel Perl, Diego Iacono, Rebecca Folkerth, William Stewart, Christine L MacDonald, Jean Augustinack, Ramon Diaz-Arrastia, Camilo Estrada, Elissa Flannery, Wayne Gordon, Tom Grabowski, Kelly Hansen, Jeanne Hoffman, Christopher Kroenke, Eric Larson, Patricia Lee, Azma Mareyam, Jennifer A McNab, Jeanne McPhee, Allison L Moreau, Anne Renz, KatieRose Richmire, Allison Stevens, Cheuk Y Tang, Lee S Tirrell, Emily Trittschuh, Andre van der Kouwe, Ani Varjabedian, Lawrence L Wald, Ona Wu, Anastasia Yendiki, Liza Young, Lilla Zollei, Bruce Fischl, Paul K Crane, Kristen Dams-O'Connor
Epidemiological studies suggest that a single moderate-to-severe traumatic brain injury (TBI) is associated with an increased risk of neurodegenerative disease, including Alzheimer's and Parkinson's disease (AD and PD). Histopathological studies describe complex neurodegenerative pathologies in individuals exposed to single moderate-to-severe TBI or repetitive mild TBI, including chronic traumatic encephalopathy (CTE). However, the clinicopathological links between TBI and post-traumatic neurodegenerative diseases such as AD, PD, and CTE remain poorly understood...
February 8, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29421679/reinforced-carbon-fiber-laminates-with-oriented-carbon-nanotube-epoxy-nanocomposites-magnetic-field-assisted-alignment-and-cryogenic-temperature-mechanical-properties
#6
Yuxin He, Song Yang, Hu Liu, Qian Shao, Qiuyu Chen, Chang Lu, Yuanli Jiang, Chuntai Liu, Zhanhu Guo
The epoxy nanocomposites with ordered multi-walled carbon nanotubes (MWCNTs) were used to influence the micro-cracks resistance of carbon fiber reinforced epoxy (CF/EP) laminate at 77 K, Oxidized MWCNTs functionalized with Fe3O4 (Fe3O4/O-MWCNTs) with good magnetic properties were prepared by co-precipitation method and used to modify epoxy (EP) for cryogenic applications. Fe3O4/O-MWCNTs reinforced carbon fiber epoxy composites were also prepared through vacuum-assisted resin transfer molding (VARTM). The ordered Fe3O4/O-MWCNTs were observed to have effectively improved the mechanical properties of epoxy (EP) matrix at 77 K and reduce the coefficient of thermal expansion (CTE) of EP matrix...
February 3, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29400641/diagnosis-makes-a-difference-perceptions-of-older-persons-with-dementia-symptoms
#7
Jed A Diekfuss, Jessica De Larwelle, Susan H McFadden
Background/Study Context: Employing the stereotype content model and terror management theory, we examined whether stereotypes and feelings about persons with dementia vary depending on the type of dementia diagnosis and purported causes of the dementia. METHODS: Participants were randomly assigned to read one of four vignettes that depicted a man who consulted his doctor because of memory problems. All vignettes described the same symptoms and diagnostic tests, but each of four groups read a different result: all tests normal (Normal); Alzheimer's disease (AD); Wernicke-Korsakoff Syndrome (WKS) associated with alcohol abuse; and chronic traumatic encephalopathy (CTE) associated with head injuries from playing football in high school and college...
February 5, 2018: Experimental Aging Research
https://www.readbyqxmd.com/read/29396300/traumatic-brain-injury-and-alzheimer-s-disease-the-cerebrovascular-link
#8
REVIEW
Jaime Ramos-Cejudo, Thomas Wisniewski, Charles Marmar, Henrik Zetterberg, Kaj Blennow, Mony J de Leon, Silvia Fossati
Traumatic brain injury (TBI) and Alzheimer's disease (AD) are devastating neurological disorders, whose complex relationship is not completely understood. Cerebrovascular pathology, a key element in both conditions, could represent a mechanistic link between Aβ/tau deposition after TBI and the development of post concussive syndrome, dementia and chronic traumatic encephalopathy (CTE). In addition to debilitating acute effects, TBI-induced neurovascular injuries accelerate amyloid β (Aβ) production and perivascular accumulation, arterial stiffness, tau hyperphosphorylation and tau/Aβ-induced blood brain barrier damage, giving rise to a deleterious feed-forward loop...
January 30, 2018: EBioMedicine
https://www.readbyqxmd.com/read/29388039/molecular-assembly-of-recombinant-chicken-type-ii-collagen-in-the-yeast-pichia-pastoris
#9
Caixia Xi, Nan Liu, Fei Liang, Xiao Zhao, Juan Long, Fang Yuan, Song Yun, Yuying Sun, Yongzhi Xi
Effective treatment of rheumatoid arthritis can be mediated by native chicken type II collagen (nCCII), recombinant peptide containing nCCII tolerogenic epitopes (CTEs), or a therapeutic DNA vaccine encoding the full-length CCOL2A1 cDNA. As recombinant CCII (rCCII) might avoid potential pathogenic virus contamination during nCCII preparation or chromosomal integration and oncogene activation associated with DNA vaccines, here we evaluated the importance of propeptide and telopeptide domains on rCCII triple helix molecular assembly...
January 9, 2018: Science China. Life Sciences
https://www.readbyqxmd.com/read/29376093/lifelong-behavioral-and-neuropathological-consequences-of-repetitive-mild-traumatic-brain-injury
#10
Benoit C Mouzon, Corbin Bachmeier, Joseph O Ojo, Christopher M Acker, Scott Ferguson, Daniel Paris, Ghania Ait-Ghezala, Gogce Crynen, Peter Davies, Michael Mullan, William Stewart, Fiona Crawford
Objective: Exposure to repetitive concussion, or mild traumatic brain injury (mTBI), has been linked with increased risk of long-term neurodegenerative changes, specifically chronic traumatic encephalopathy (CTE). To date, preclinical studies largely have focused on the immediate aftermath of mTBI, with no literature on the lifelong consequences of mTBI in these models. This study provides the first account of lifelong neurobehavioral and histological consequences of repetitive mTBI providing unique insight into the constellation of evolving and ongoing pathologies with late survival...
January 2018: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/29362760/a-comparison-of-the-sensory-and-rheological-properties-of-different-cellulosic-fibres-for-food
#11
Deepa Agarwal, Louise Hewson, Tim J Foster
The impact of different cellulosic microstructures formed by highly entangled fibre networks was studied for food applications as dietary fibre. This paper reports the impact of the microstructure on the rheological and sensory behaviour of the aqueous suspensions of particulate and fibrillated forms of softwood cellulosic fibres, and was compared with citrus fibres. An aqueous suspension of cellulosic fibres shows stable viscoelastic gel-like behaviour as a function of frequency. The particulate form of cellulosic fibres showed the lowest shear viscosity as compared with the entangled network system at comparable concentrations...
January 24, 2018: Food & Function
https://www.readbyqxmd.com/read/29338612/gene-profiling-of-nucleus-basalis-tau-containing-neurons-in-chronic-traumatic-encephalopathy-a-chronic-effects-of-neurotrauma-consortium-study
#12
Elliott Jay Mufson, Bin He, Stephen D Ginsberg, Benjamin A Carper, Gayle S Bieler, Fiona C Crawford, Victor E Alverez, Bernard R Huber, Thor D Stein, Ann C McKee, Sylvia E Perez
Military personnel and athletes exposed to traumatic brain injury may develop chronic traumatic encephalopathy (CTE). Brain pathology in CTE includes intracellular accumulation of abnormally phosphorylated tau proteins (p-tau), the main constituent of neurofibrillary tangles (NFTs). Recently, we found that cholinergic basal forebrain (CBF) neurons within the nucleus basalis of Meynert (nbM), which provide the major cholinergic innervation to the cortex, display an increasing number of NFTs across the pathological stages of CTE...
January 16, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29328330/evaluation-of-thermal-expansion-coefficient-of-carbon-fiber-reinforced-composites-using-electronic-speckle-interferometry
#13
Chengzhi Dong, Kai Li, Yuxi Jiang, Dwayne Arola, Dongsheng Zhang
An optical system for measuring the coefficient of thermal expansion (CTE) of materials has been developed based on electronic speckle interferometry. In this system, the temperature can be varied from -60°C to 180°C with a Peltier device. A specific specimen geometry and an optical arrangement based on the Michelson interferometer are proposed to measure the deformation along two orthogonal axes due to temperature changes. The advantages of the system include its high sensitivity and stability over the whole range of measurement...
January 8, 2018: Optics Express
https://www.readbyqxmd.com/read/29322612/validation-of-contemporary-risk-scores-in-predicting-coronary-thrombotic-events-and-major-bleeding-in-patients-with-acute-coronary-syndrome-after-drug-eluting-stent-implantations
#14
Li Song, Changdong Guan, Hongbing Yan, Shubin Qiao, Yongjian Wu, Jinqing Yuan, Kefei Dou, Yuejin Yang, George D Dangas, Bo Xu
OBJECTIVES: We aimed to assess the prognostic ability of the ST score, DAPT score, and PARIS score in a Chinese population. BACKGROUND: Recently, several risk scores predicting the long-term risk of coronary thrombotic events [CTE, defined as the composite of definite or probable stent thrombosis (ST) and myocardial infarction] and bleeding have been developed and initially validated in Western populations. METHODS: A total of 6,088 consecutive patients with acute coronary syndrome (mean age 58...
January 11, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29321231/chronic-traumatic-encephalopathy-in-an-epilepsy-surgery-cohort-clinical-and-pathologic-findings
#15
Amy L Jones, Jeffrey W Britton, Melissa M Blessing, Joseph E Parisi, Gregory D Cascino
OBJECTIVE: To determine the occurrence of chronic traumatic encephalopathy (CTE) in young adult patients undergoing epilepsy surgery. METHODS: Ten patients who underwent epilepsy surgery were randomly selected for this retrospective study. The patients were 18-45 years of age, had preoperative neuropsychological evaluation, and had 1 year postoperative follow-up. Microscopic sections from resections were evaluated for the presence of CTE with standard stains and antibodies to tau (clone AT8)...
January 10, 2018: Neurology
https://www.readbyqxmd.com/read/29310631/acute-effect-of-clitoria-ternatea-flower-beverage-on-glycemic-response-and-antioxidant-capacity-in-healthy-subjects-a-randomized-crossover-trial
#16
Charoonsri Chusak, Thavaree Thilavech, Christiani Jeyakumar Henry, Sirichai Adisakwattana
BACKGROUND: Clitoria ternatea L., a natural food-colorant containing anthocyanin, demonstrated antioxidant and antihyperglycemic activity. The aim of this study was to determine the effects of Clitoria ternatea flower extract (CTE) on postprandial plasma glycemia response and antioxidant status in healthy men. METHODS: In a randomized, crossover study, 15 healthy men (ages 22.53 ± 0.30 years; with body mass index of 21.57 ± 0.54 kg/m2) consumed five beverages: (1) 50 g sucrose in 400 mL water; (2) 1 g CTE in 400 mL of water; (3) 2 g CTE in 400 mL of water; (4) 50 g sucrose and 1 g CTE in 400 mL of water; and (5) 50 g sucrose and 2 g CTE in 400 mL of water...
January 8, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29300327/on-the-alloying-and-properties-of-tetragonal-nb%C3%A2-si%C3%A2-in-nb-silicide-based-alloys
#17
Panos Tsakiropoulos
The alloying of Nb₅Si₃ modifies its properties. Actual compositions of (Nb,TM)₅X₃ silicides in developmental alloys, where X = Al + B + Ge + Si + Sn and TM is a transition and/or refractory metal, were used to calculate the composition weighted differences in electronegativity (Δχ) and an average valence electron concentration (VEC) and the solubility range of X to study the alloying and properties of the silicide. The calculations gave 4.11 < VEC < 4.45, 0.103 < Δχ < 0.415 and 33.6 < X < 41...
January 4, 2018: Materials
https://www.readbyqxmd.com/read/29298849/pathologic-thr175-tau-phosphorylation-in-cte-and-cte-with-als
#18
Alexander J Moszczynski, Wendy Strong, Kathy Xu, Ann McKee, Arthur Brown, Michael J Strong
OBJECTIVE: To investigate whether chronic traumatic encephalopathy (CTE) and CTE with amyotrophic lateral sclerosis (CTE-ALS) exhibit features previously observed in other tauopathies of pathologic phosphorylation of microtubule-associated protein tau at Thr175 (pThr175 tau) and Thr231 (pThr231 tau), and glycogen synthase kinase-3β (GSK3β) activation, and whether these pathologic features are a consequence of traumatic brain injury (TBI). METHODS: Tau isoform expression was assayed by western blot in 6 stage III CTE cases...
January 3, 2018: Neurology
https://www.readbyqxmd.com/read/29276758/role-of-tau-acetylation-in-alzheimer-s-disease-and-chronic-traumatic-encephalopathy-the-way-forward-for-successful-treatment
#19
Brandon Lucke-Wold, Kay Seidel, Rub Udo, Bennet Omalu, Mark Ornstein, Richard Nolan, Charles Rosen, Joel Ross
Progressive neurodegenerative diseases plague millions of individuals both in the United States and across the world. The current pathology of progressive neurodegenerative tauopathies, such as Alzheimer's disease (AD), Pick's disease, frontotemporal dementia (FTD), and progressive supranuclear palsy, primarily revolves around phosphorylation and hyperphosphorylation of the tau protein. However, more recent evidence suggests acetylation of tau protein at lysine 280 may be a critical step in molecular pathology of these neurodegenerative diseases prior to the tau hyperphosphorylation...
2017: Journal of Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29261354/prospective-comparison-of-standard-versus-low-radiation-dose-ct-enterography-for-the-quantitative-assessment-of-crohn-disease
#20
Greg Rosenfeld, Jacqueline Brown, Patrick M Vos, Jonathon Leipsic, Robert Enns, Brian Bressler
OBJECTIVE: CT enterography (CTE) is sensitive and specific for active inflammatory changes of Crohn disease (CD), but its use has been limited by exposure to ionizing radiation. The objective of this study is to show the noninferiority of a model-based iterative reconstruction (MBIR) technique using lower radiation doses compared with standard-dose CTE in the assessment of CD. SUBJECTS AND METHODS: Patients referred to a hospital radiology department for CTE for the evaluation of CD underwent both a standard examination (used to generate filtered back-projection and adaptive statistical iterative reconstruction [ASIR] images) and low-dose MBIR CTE performed in a random sequence on the same day...
February 2018: AJR. American Journal of Roentgenology
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