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https://www.readbyqxmd.com/read/29784261/reduction-of-postanesthetic-pediatric-distress-a-coordinated-approach
#1
Simon Hayhoe, Scott Pallett, Juliet Zani, Joanne Trott
PURPOSE: Preoperative anxiety in children is associated with postoperative distress in recovery. Both are predictors of long-term maladaptive behavior. Remedies have been suggested to modify individual risk factors, but overall strategy is lacking. DESIGN: An approach to anxiety reduction coordinated throughout the hospital experience has been developed in our day-stay pediatric surgical unit. METHODS: There is a preadmission familiarization visit...
June 2018: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/29774619/different-types-of-multiple-synapse-boutons-in-the-cerebellar-cortex-between-physically-enriched-and-ataxic-mutant-mice
#2
Hyun-Wook Kim, Seunghak Oh, Seung Hwan Lee, Sanghoon Lee, Ji-Eun Na, Kea Joo Lee, Im Joo Rhyu
Experience-dependent synapse remodeling is associated with information storage in the nervous system. Neuronal synapses show alteration in various neurological and cognitive disorders in their structure and function. At the ultrastructural level, parallel fiber boutons contacting multiple spines of Purkinje cells in the cerebellar cortex are commonly observed in physiologically enriched animals as well as pathological ataxic mutants. However, the dendritic origin of those spines on parallel fiber multiple-synapse boutons (MSBs) has been poorly understood...
May 18, 2018: Microscopy Research and Technique
https://www.readbyqxmd.com/read/29762531/synthesis-spectroscopic-and-biological-studies-of-mixed-ligand-complexes-of-gemifloxacin-and-glycine-with-zn-ii-sn-ii-and-ce-iii
#3
Shimaa H Sakr, Hazem S Elshafie, Ippolito Camele, Sadeek A Sadeek
Three novel mixed ligand metal complexes have been synthesized by the reaction of Zn(II), Sn(II), and Ce(III) with gemifloxacin (GMFX) in the presence of glycine (Gly) (1:1:1 molar ratio). The coordination possibility of the two ligands toward metal ions has been proposed in the light of elemental analysis, molar conductance, spectral infrared (IR), ultraviolet-visible (UV-Vis) and proton-nuclear magnetic resonance (¹H NMR), and magnetic studies. Results suggest that GMFX and Gly interact with the metal ions as bidentate ligands...
May 15, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29757941/exploring-how-the-home-environment-influences-eating-and-physical-activity-habits-of-low-income-latino-children-of-predominantly-immigrant-families-a-qualitative-study
#4
Ana Cristina Lindsay, Sherrie F Wallington, Faith D Lees, Mary L Greaney
Latinos are the largest and fastest growing minority population group in the United States, and children in low-income Latino families are at elevated risk of becoming overweight or having obesity. A child’s home is an important social environment in which he/she develops and maintains dietary and physical activity (PA) habits that ultimately impact weight status. Previous research suggests the parents are central to creating a home environment that facilitates or hinders the development of children’s early healthy eating and PA habits...
May 14, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29757076/economic-evaluation-of-concussion-programs-in-the-state-of-idaho-the-collective-potential-of-prevention-and-clinical-care
#5
Susie Bergeron, Hilary Flint, Zeynep Hansen
Concussion, or mild traumatic brain injury, especially among young children, teenagers, and young adults, is a significant problem in Ada County, Idaho, and the United States. Although much has been learned about concussion, considerable controversy and gaps in knowledge still exist in many areas of research, leading to variation in concussion assessment, treatment, and management protocols. Health systems can positively impact concussion outcomes through community education and outreach, and provision of timely, coordinated, evidence-based clinical care...
May 14, 2018: Population Health Management
https://www.readbyqxmd.com/read/29750858/a-mof-with-cooperative-phosphines-that-permits-post-synthetic-installation-of-open-metal-sites
#6
Samuel G Dunning, Gianne Nandra, Adam D Conn, Wenrui Chai, R Eric Sikma, Ji-Sung Lee, Pranaw Kunal, Joseph E Reynolds Iii, Jong-San Chang, Alexander Steiner, Graeme Henkelman, Simon Michael Humphrey
PCM-101 is a new phosphine coordination material comprised of tris(p-carboxylato)triphenylphosphine and secondary pillaring groups coordinated to [M3(OH)]5+ nodes (M = Co, Ni). PCM-101 has a unique topology in which R3P: sites are arranged directly trans- to one another, with a P···P separation distance dictated by the pillars. Post-synthetic coordination of soft metals to the P: sites proceeds at room temperature to provide X-ray quality crystals that permit full structural resolution. Addition of AuCl groups forces a large distortion of the parent framework...
May 11, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29739396/how-well-do-services-for-young-people-with-long-term-conditions-deliver-features-proposed-to-improve-transition
#7
A Colver, R Pearse, R M Watson, M Fay, T Rapley, K D Mann, A Le Couteur, J R Parr, H McConachie
BACKGROUND: For young people with long-term conditions, transition from child to adult-oriented health services is a critical period which, if not managed well, may lead to poor outcomes. There are features of transition services which guidance and research suggest improve outcomes. We studied nine such features, calling them 'proposed beneficial features': age-banded clinic; meet adult team before transfer; promotion of health self-efficacy; written transition plan; appropriate parent involvement; key worker; coordinated team; holistic life-skills training; transition manager for clinical team...
May 8, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29738104/differential-expression-networks-and-inheritance-patterns-of-long-non-coding-rnas-in-castor-bean-seeds
#8
Wei Xu, Tianquan Yang, Bin Wang, Bing Han, Huangkai Zhou, Yue Wang, De-Zhu Li, Aizhong Liu
Long non-coding RNAs (lncRNAs) serve as versatile regulators of plant growth and development. The potential functions and inheritance patterns of lncRNAs, as well as the epigenetic regulation of lncRNA itself, remain largely uncharacterized in plant seeds, especially in the persistent endosperm of the dicotyledons. In this study, we investigated diverse RNA-seq data and catalogued 5,356 lncRNAs in castor bean seeds. A small fraction of lncRNAs were transcribed from the same direction as the promoters of protein-coding genes (PCgenes) and exhibited strongly coordinated expression with the nearby PCgene...
May 8, 2018: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/29736112/still-hoping-for-a-miracle-parents-experiences-in-caring-for-their-child-with-cancer-under-palliative-care
#9
Mercy Nafratilova, Allenidekania Allenidekania, Dessie Wanda
Context: Parents' despair and feelings of grief, as well as communication and coordination that is less than adequate between the parents and the palliative team, can affect the provision of a qualified palliative care plan for children and their families. Aims: This study aims to explore the parents' experience in caring for children with cancer under palliative care condition. Setting and Design: The research applied descriptive qualitative phenomenology design...
April 2018: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/29735606/allele-specific-control-of-replication-timing-and-genome-organization-during-development
#10
Juan Carlos Rivera-Mulia, Andrew Dimond, Daniel Vera, Claudia Trevilla-Garcia, Takayo Sasaki, Jared Zimmerman, Catherine Dupont, Joost Gribnau, Peter Fraser, David M Gilbert
DNA replication occurs in a defined temporal order known as the replication-timing (RT) program. RT is regulated during development in discrete chromosomal units, coordinated with transcriptional activity and 3D genome organization. Here, we derived distinct cell types from F1 hybrid musculus X castaneus mouse crosses and exploited the high single nucleotide polymorphism (SNP) density to characterize allelic differences in RT (Repli-seq), genome organization (Hi-C and promoter-capture Hi-C), gene expression (total nuclear RNA-seq) and chromatin accessibility (ATAC-seq)...
May 7, 2018: Genome Research
https://www.readbyqxmd.com/read/29729682/structural-covariance-and-cortical-reorganisation-in-schizophrenia-a-mri-based-morphometric-study
#11
Lena Palaniyappan, Olha Hodgson, Vijender Balain, Sarina Iwabuchi, Penny Gowland, Peter Liddle
BACKGROUND: In patients with schizophrenia, distributed abnormalities are observed in grey matter volume. A recent hypothesis posits that these distributed changes are indicative of a plastic reorganisation process occurring in response to a functional defect in neuronal information transmission. We investigated the structural covariance across various brain regions in early-stage schizophrenia to determine if indeed the observed patterns of volumetric loss conform to a coordinated pattern of structural reorganisation...
May 6, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29724641/identifying-patterns-of-motor-performance-executive-functioning-and-verbal-ability-in-preschool-children-a-latent-profile-analysis
#12
Suzanne Houwen, Erica Kamphorst, Gerda van der Veer, Marja Cantell
BACKGROUND: A relationship between motor performance and cognitive functioning is increasingly being recognized. Yet, little is known about the precise nature of the relationship between both domains, especially in early childhood. AIMS: To identify distinct constellations of motor performance, executive functioning (EF), and verbal ability in preschool aged children; and to explore how individual and contextual variables are related to profile membership. METHODS AND PROCEDURES: The sample consisted of 119 3- to 4-year old children (62 boys; 52%)...
April 30, 2018: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29723752/prenatal-lead-cadmium-and-mercury-exposure-and-associations-with-motor-skills-at-age-7-years-in-a-uk-observational-birth-cohort
#13
Caroline M Taylor, Alan M Emond, Raghu Lingam, Jean Golding
BACKGROUND: Lead and mercury are freely transferred across the placenta, while cadmium tends to accumulate in the placenta. Each contributes to adverse neurological outcomes for the child. Although prenatal heavy metal exposure has been linked with an array of neurodevelopmental outcomes in childhood, its association with the development of motor skills in children has not been robustly studied. AIMS/OBJECTIVE: The aim of the present study was to investigate the association between prenatal exposure to lead, cadmium and mercury, measured as maternal blood concentrations during pregnancy, and motor skills, measured as subtests of the Movement Assessment Battery for Children (Movement ABC) at age 7 years in a large sample of mother-child pairs enrolled in a UK observational birth cohort study (Avon Longitudinal Study of Parents and Children, ALSPAC)...
April 30, 2018: Environment International
https://www.readbyqxmd.com/read/29716738/neuropsychological-consequences-of-childhood-medulloblastoma-and-possible-interventions-a-review
#14
E Doger de Spéville, V Kieffer, C Dufour, J Grill, M Noulhiane, L Hertz-Pannier, M Chevignard
BACKGROUND: Children who have been treated for a medulloblastoma often suffer long-term cognitive impairments that often negatively affect their academic performance and quality of life. In this article, we will review the neuropsychological consequences of childhood medulloblastoma and discuss the risk factors known to influence the presence and severity of these cognitive impairments and possible interventions to improve their quality of life. METHODS: This narrative review was based on electronic searches of PubMed to identify all relevant studies...
April 28, 2018: Neuro-Chirurgie
https://www.readbyqxmd.com/read/29716553/protocol-for-a-cluster-randomised-controlled-trial-evaluating-the-impact-of-a-preschool-based-capacity-building-intervention-on-intimate-partner-violence-and-substance-misuse-in-sri-lanka
#15
Kamalini Lokuge, Polly Wallace, Kalini Subasinghe, Katherine Thurber, Tissa De Silva, Naomi Clarke, Dulshika Waas, Nisansala Liyanage, Udena Attygalle, Bradley Carron-Arthur, Kalyana Rodrigo, Emily Banks, Cate D'Este, Thilini Rajapakse
BACKGROUND: Past research has identified links between intimate partner violence (IPV) and alcohol misuse and poverty in Sri Lanka. Services that address substance misuse are amongst the few interventions shown to reduce IPV in settings similar to Sri Lanka. This paper describes the protocol for a study examining the impact of a preschool-based capacity building intervention on the prevalence of IPV and substance misuse in parents with children attending preschools, including uptake of available government services...
May 2, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29713242/caring-for-late-preterm-infants-public-health-nurses-experiences
#16
Genevieve Currie, Aliyah Dosani, Shahirose S Premji, Sandra M Reilly, Abhay K Lodha, Marilyn Young
Background: Public health nurses (PHNs) care for and support late preterm infants (LPIs) and their families when they go home from the hospital. PHNs require evidence-informed guidelines to ensure appropriate and consistent care. The objective of this research study is to capture the lived experience of PHNs caring for LPIs in the community as a first step to improving the quality of care for LPIs and support for their parents. Methods: To meet our objectives we chose a descriptive phenomenology approach as a method of inquiry...
2018: BMC Nursing
https://www.readbyqxmd.com/read/29700935/a-qualitative-study-of-the-role-of-playgroups-in-building-community-capacity
#17
Georgia Keam, Kay Cook, Sarah Sinclair, Ian McShane
ISSUE ADDRESSED: Given that approximately half of all Australian families with children aged 2-3 years participate in playgroups, these settings may provide an important venue for social support and community capacity building. The aim of this study is to assess the benefits that parents and the wider community derive from such participation. METHODS: We examined community capacity building opportunities through qualitative interviews conducted with a self-selected sample of 33 playgroup participants...
April 2018: Health Promotion Journal of Australia
https://www.readbyqxmd.com/read/29694803/stolonial-movement-a-new-type-of-whole-organism-behavior-in-porifera
#18
Andrey I Lavrov, Igor A Kosevich
Sponges (phylum Porifera) traditionally are represented as inactive, sessile filter-feeding animals devoid of any behavior except filtering activity. However, different time-lapse techniques demonstrate that sponges are able to show a wide range of coordinated but slow whole-organism behavior. The present study concerns a peculiar type of such behavior in the psychrophilic demosponge Amphilectus lobatus: stolonial movement. During stolonial movement, sponges produce outgrowths (stolons) that crawl along a substrate with a speed of 4...
February 2018: Biological Bulletin
https://www.readbyqxmd.com/read/29688990/epidemiology-and-impact-of-health-care-provider-diagnosed-anxiety-and-depression-among-us-children
#19
Rebecca H Bitsko, Joseph R Holbrook, Reem M Ghandour, Stephen J Blumberg, Susanna N Visser, Ruth Perou, John T Walkup
OBJECTIVE: This study documents the prevalence and impact of anxiety and depression in US children based on the parent report of health care provider diagnosis. METHODS: National Survey of Children's Health data from 2003, 2007, and 2011-2012 were analyzed to estimate the prevalence of anxiety or depression among children aged 6 to 17 years. Estimates were based on the parent report of being told by a health care provider that their child had the specified condition...
April 24, 2018: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29688242/salt-metathesis-routes-to-homoleptic-near-linear-mg-ii-and-ca-ii-bulky-bis-silyl-amide-complexes
#20
Ji-Dong Leng, Conrad A P Goodwin, Iñigo J Vitorica-Yrezabal, David P Mills
Herein we investigate salt metathesis reactions of bulky bis(silyl)amide potassium salts [K{N(SiMe2tBu)2}]n, [K{N(SiMe2tBu)(SiiPr3)}]n, [K{N(SiiPr3)2}]n and [K{N(SiPh3)2}]n (1) with AeI2 (Ae = Mg, Ca, Sr) in an effort to synthesise rare homoleptic two-coordinate complexes. Recrystallization of 1 from THF provided structural authentication of the solvated adduct [K{N(SiPh3)2}(THF)3] (1-THF). For Ae = Mg we were able to identify products for three of the four bis(silyl)amides investigated: [Mg{N(SiMe2tBu)2}2(THF)] (2), [Mg{N(SiMe2tBu)(SiiPr3)}2] (3) and [Mg{N(SiPh3)2}2] (4)...
April 24, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
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