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https://www.readbyqxmd.com/read/27891568/oral-hygiene-compliance-in-orthodontic-patients-a-randomized-controlled-study-on-the-effects-of-a-post-treatment-communication
#1
Mauro Cozzani, Giulia Ragazzini, Alessia Delucchi, Sabrina Mutinelli, Carlo Barreca, Daniel J Rinchuse, Roberto Servetto, Vincenzo Piras
BACKGROUND: Several studies have recently demonstrated that a post-treatment communication to explain the importance of an oral hygiene can improve the orthodontic patients' compliance over a period of 66 days. The main goal of this study is to evaluate the effects of a structured follow-up communication after orthodontic appliance application on oral hygiene compliance after 30-40 days. METHODS: Eighty-four orthodontic participants enrolled from patients who were beginning fixed orthodontic treatment at the Orthodontic Department, Gaslini Hospital, Genova, between July and October 2014 were randomly assigned to one of three trial arms...
December 2016: Progress in Orthodontics
https://www.readbyqxmd.com/read/27648002/regulatory-snps-alter-the-gene-expression-of-diabetic-retinopathy-associated-secretary-factors
#2
Chian-Feng Chen, Shiow-Wen Liou, Hsin-Han Wu, Chin-Hui Lin, Li-Shan Huang, Lin-Chung Woung, Ching-Yao Tsai
Objectives: Diabetic retinopathy (DR) is a common microvascular complication in both type I and type II diabetes. Several previous reports indicated the serum centration of some secretary factors were highly associated with DR. Therefore, we hypothesis regulatory SNPs (rSNPs) genotype in secretary factors may alter these gene expression and lead to DR. Methods: At first, pyrosequencing were applying to screen the SNPs which present allele frequency different in DR and DNR. Then individual genotyping was processed by Taqman assays in Taiwanese DR and DNR patients...
2016: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/27617874/visualization-of-tear-clearance-using-anterior-segment-optical-coherence-tomography-and-polymethylmethacrylate-particles
#3
Xiaodong Zheng, Masahiko Yamaguchi, Tomoyuki Kamao, Yuri Sakane, Tomoko Goto, Atsushi Shiraishi, Yuichi Ohashi
We previously reported 2 new methods, anterior segment optical coherence tomography (AS-OCT) and polymethylmethacrylate particles suspended in fluorescein solution (PPF), for the evaluation of tear clearance and rapid tear flow after blinking (tear Krehbiel flow). Here, we investigated age-related OCT tear clearance and tear film thickness (TFT) and the potential correlation of OCT tear clearance and PPF velocity indicative of tear Krehbiel flow. Normal subjects separated into young and older groups received 5 μL of saline solution into the lower conjunctival sac, and an image of the central lower eyelid tear meniscus was captured by AS-OCT immediately and 30 seconds after natural blinking...
November 2016: Cornea
https://www.readbyqxmd.com/read/27474751/regulation-of-ugt2b-expression-and-activity-by-mir-216b-5p-in-liver-cancer-cell-lines
#4
Douglas F Dluzen, Aimee K Sutliff, Gang Chen, Christy J W Watson, Faoud T Ishmael, Philip Lazarus
The UDP-glucuronosyltransferase (UGT) 2B enzymes are important in the detoxification of a variety of endogenous and exogenous compounds, including many hormones, drugs, and carcinogens. Identifying novel mechanisms governing their expression is important in understanding patient-specific response to drugs and cancer risk factors. In silico prediction algorithm programs were used to screen for microRNAs (miRNAs) as potential regulators of UGT2B enzymes, with miR-216b-5p identified as a potential candidate. Luciferase data suggested the presence of a functional miR-216b-5p binding motif within the 3' untranslated regions of UGTs 2B7, 2B4, and 2B10...
October 2016: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/27454634/recovery-of-wrist-function-after-volar-locking-plate-fixation-for-distal-radius-fractures
#5
Naohide Takeuchi, Shunsuke Hotokezaka, Takamitsu Okada, Hidehiko Yuge, Takao Mae, Yukihide Iwamoto
BACKGROUND: The purpose of our present study was to examine the recovery of the postoperative wrist function, and to compare the range of motion among each direction ofthe wrist joint during the same time periods after surgery for distal radius fractures. METHODS: Twenty patients treated with a volar locking plate were evaluated. The active range of motion and grip strength were assessed at four weeks, six weeks, three months, six months and one year after surgery...
June 2016: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/27438849/molecular-and-genetic-characterization-of-hiv-1-tat-exon-1-gene-from-cameroon-shows-conserved-tat-hla-binding-epitopes-functional-implications
#6
Georges Teto, Julius Y Fonsah, Claude T Tagny, Dora Mbanya, Emilienne Nchindap, Leopoldine Kenmogne, Joseph Fokam, Dora M Njamnshi, Charles Kouanfack, Alfred K Njamnshi, Georgette D Kanmogne
HIV-1 Tat plays a critical role in viral transactivation. Subtype-B Tat has potential use as a therapeutic vaccine. However, viral genetic diversity and population genetics would significantly impact the efficacy of such a vaccine. Over 70% of the 37-million HIV-infected individuals are in sub-Saharan Africa (SSA) and harbor non-subtype-B HIV-1. Using specimens from 100 HIV-infected Cameroonians, we analyzed the sequences of HIV-1 Tat exon-1, its functional domains, post-translational modifications (PTMs), and human leukocyte antigens (HLA)-binding epitopes...
2016: Viruses
https://www.readbyqxmd.com/read/27329552/improved-survival-in-patients-with-severe-tuberculosis-after-exposure-to-fluoroquinolones
#7
Shyh-Ren Chiang, Jiunn-Min Shieh, Chung-Hua Chen, Shu-Chen Hsing, Shih-Feng Wen, Jhi-Joung Wang, Kuo-Chen Cheng, Yin-Ching Chuang
BACKGROUND: The clinical impact of prior exposure to antibiotics on patients with tuberculosis (TB) is largely unknown. This study investigated the survival of patients with severe TB after exposure to a variety of antibiotics. METHODS: A retrospective cohort study was conducted in TB patients with prior exposure to fluoroquinolones (FQs) (FQ group), to third-generation cephalosporins (CEPH group), and to third-generation penicillins (PCN group). To understand the impact of monotherapy with antibiotics on survival, patients with prior exposure to only moxifloxacin, ceftriaxone, or piperacillin were investigated...
November 2016: Infectious Diseases
https://www.readbyqxmd.com/read/27194857/mounting-ground-sections-of-teeth-cyanoacrylate-adhesive-versus-canada-balsam
#8
Manogna Rl Vangala, Amrutha Rudraraju, R V Subramanyam
INTRODUCTION: Hard tissues can be studied by either decalcification or by preparing ground sections. Various mounting media have been tried and used for ground sections of teeth. However, there are very few studies on the use of cyanoacrylate adhesive as a mounting medium. AIMS: The aim of our study was to evaluate the efficacy of cyanoacrylate adhesive (Fevikwik™) as a mounting medium for ground sections of teeth and to compare these ground sections with those mounted with Canada balsam...
January 2016: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/27166592/model-development-and-experimental-validation-of-capnophilic-lactic-fermentation-and-hydrogen-synthesis-by-thermotoga-neapolitana
#9
Nirakar Pradhan, Laura Dipasquale, Giuliana d'Ippolito, Angelo Fontana, Antonio Panico, Francesco Pirozzi, Piet N L Lens, Giovanni Esposito
The aim of the present study was to develop a kinetic model for a recently proposed unique and novel metabolic process called capnophilic (CO2-requiring) lactic fermentation (CLF) pathway in Thermotoga neapolitana. The model was based on Monod kinetics and the mathematical expressions were developed to enable the simulation of biomass growth, substrate consumption and product formation. The calibrated kinetic parameters such as maximum specific uptake rate (k), semi-saturation constant (kS), biomass yield coefficient (Y) and endogenous decay rate (kd) were 1...
August 1, 2016: Water Research
https://www.readbyqxmd.com/read/27091136/early-phase-wound-healing-and-long-term-outcomes-of-a-selective-endovascular-first-approach-for-treating-rutherford-5-critical-limb-ischemia-with-infrainguinal-lesions
#10
Kentaro Inoue, Toshihiro Onohara, Keita Mikasa, Tadashi Furuyama
PURPOSE: To evaluate the validity of a selective endovascular-first approach for Rutherford 5 critical limb ischemia (CLI). METHODS: We analyzed, retrospectively, 51 limbs in 46 patients treated for Rutherford 5 CLI with infrainguinal lesions between 2010 and 2012. Endovascular therapy (EVT) and open surgical revascularization (OSR) were performed initially in 28 and 23 limbs, respectively. The interventions were assigned according to the systemic condition and femoropopiliteal TransAtlantic Inter-Society Consensus (TASC) II classification...
November 2016: Surgery Today
https://www.readbyqxmd.com/read/27045933/particle-scale-modeling-of-methane-emission-during-pig-manure-wheat-straw-aerobic-composting
#11
Jinyi Ge, Guangqun Huang, Jing Huang, Jianfei Zeng, Lujia Han
Inefficient aerobic composting techniques significantly contribute to the atmospheric methane (CH4) levels. Macro-scale models assuming completely aerobic conditions cannot be used to analyze CH4 generation in strictly anaerobic environments. This study presents a particle-scale model for aerobic pig manure/wheat straw composting that incorporates CH4 generation and oxidation kinetics. Parameter estimation revealed that pig manure is characterized by high CH4 yield coefficient (0.6414 mol CH4 mol(-1) Cman) and maximum CH4 oxidation rate (0...
April 19, 2016: Environmental Science & Technology
https://www.readbyqxmd.com/read/26834421/efficacy-and-safety-of-a-polyherbal-formulation-in-hemorrhoids
#12
Raakhi K Tripathi, Somesh S Bolegave, Parvan A Shetty, Dinesh A Uchil, Nirmala N Rege, Mukesh B Chawda, Sameer A Rege
BACKGROUND: The medical management of hemorrhoids should include an integrated approach. This integrated approach can be achieved by polyherbal formulations containing anti-inflammatory, styptics, analgesics, and laxative effect which reduce inflammation, pain, and bleeding, and increase gastro-intestinal motility and soften stools. One such polyherbal kit is "Arshkeyt™, a 7 day kit," which consists of oral tablets and powder along with topical cream. OBJECTIVE: Efficacy and safety of Arshkeyt™, a 7 day kit, a marketed polyherbal formulation was evaluated in comparison with conventional therapy practiced in surgery outpatient departments...
October 2015: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/26824973/five-year-follow-up-and-recurrence-rates-following-surgery-for-acute-and-chronic-pilonidal-disease-a-survey-of-421-cases
#13
Gabriela Tonia Fahrni, Raphael Nicolas Vuille-Dit-Bille, Svenja Leu, Martin Meuli, Ralph Fabian Staerkle, Lukas Fink, Selim Dinçler, Brigitte Susanne Muff
OBJECTIVE: The aim of the present study was to investigate the outcomes of different treatment options for acute and chronic pilonidal disease in a single large cohort of patients. MATERIALS AND METHODS: Four hundred and twenty-one consecutive patients (171 with chronic disease and 250 with acute abscess formation) who underwent surgery between 2003 and 2012 were included in the present study. Primary outcomes included symptomatic recurrence, time to wound healing, and time off from work...
January 2016: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/26792986/impact-of-individualized-care-on-readmissions-after-a-hospitalization-for-acute-exacerbation-of-copd
#14
Simon L Adamson, Jane Burns, Pat G Camp, Don D Sin, Stephan F van Eeden
BACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) increase COPD morbidity and mortality and impose a great burden on health care systems. Early readmission following a hospitalization for AECOPD remains an important clinical problem. We examined how individualized comprehensive care influences readmissions following an index hospital admission for AECOPD. METHODS: We retrospectively reviewed data of patients admitted for AECOPD to two inner-city teaching hospitals to determine the impact of a comprehensive and individualized care management strategy on readmissions for AECOPD...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/26509351/body-fat-differences-by-self-reported-race-ethnicity-in-healthy-term-newborns
#15
C Paley, H Hull, Y Ji, T Toro-Ramos, J Thornton, J Bauer, P Matthews, A Yu, K Navder, K Dorsey, D Gallagher
BACKGROUND: Ethnic differences in total body fat (fat mass [FM]) have been reported in adults and children, but the timing of when these differences manifest and whether they are present at birth are unknown. OBJECTIVES: This study aimed to assess whether ethnic differences in body fat are present at birth in healthy infants born at term, where body fat is measured using air displacement plethysmography and fat distribution by skin-fold thickness. METHODS: Data were from a multiracial cross-sectional convenience sample of 332 term infants from four racial or ethnic groups based on maternal self-report (A, Asian; AA, non-Hispanic Black [African-American]; C, non-Hispanic White; and H, Hispanic)...
October 2016: Pediatric Obesity
https://www.readbyqxmd.com/read/26327767/histological-outcome-for-chronic-hepatitis-b-patients-treated-with-entecavir-vs-lamivudine-based-therapy
#16
COMPARATIVE STUDY
Jia-Li Wang, Xin-Fang Du, Shao-Long Chen, Yi-Qi Yu, Jing Wang, Xi-Qi Hu, Ling-Yun Shao, Jia-Zhen Chen, Xin-Hua Weng, Wen-Hong Zhang
AIM: To compare the histological outcome of chronic hepatitis B (CHB) patients treated with entecavir (ETV) or lamivudine (LAM)-based therapy. METHODS: We conducted a retrospective analysis of data from 42 CHB patients with advanced fibrosis (baseline Ishak score ≥ 2) or cirrhosis who were treated with ETV or LAM-based therapy in Beilun People's Hospital, Ningbo between January 2005 and May 2012. The patients enrolled were more than 16 years of age and underwent a minimum of 12 mo of antiviral therapy...
August 28, 2015: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/26137433/imbalance-in-the-blood-antioxidant-system-in-growth-hormone-deficient-children-before-and-after-1-year-of-recombinant-growth-hormone-therapy
#17
Maria S Pankratova, Adil A Baizhumanov, Alexander I Yusipovich, Maria Faassen, Tatyana Yu Shiryaeva, Valentina A Peterkova, Svetlana S Kovalenko, Tatiana A Kazakova, Georgy V Maksimov
The aim of our study was to examine the effects of 12-month therapy with recombinant growth hormone (rGH) on the blood antioxidant system in children with growth hormone deficiency (GHD). Total antioxidant capacity (TAC) of plasma was measured by FRAP (ferric reducing antioxidant power or ferric reducing ability of plasma); activities of superoxide dismutase (SOD) and catalase (CAT) in erythrocytes were assessed; non-protein thiols (NT) and ceruloplasmin (CP) levels were also measured. These parameters were determined before and after 12 month of rGH treatment...
2015: PeerJ
https://www.readbyqxmd.com/read/26060640/a-study-of-risk-factors-and-t-score-variability-in-romanian-women-with-postmenopausal-osteoporosis
#18
Rodica TöRöK-Oance
BACKGROUND: The purpose of this study was to analyse the prevalence of postmenopausal osteoporosis risk factors and to analyse the T-score variability in spine and hip according to the associated risk factors. METHODS: This is a retrospective study (2003-2007) including 177 female patients with postmenopausal osteoporosis. The patients were separated in seven groups according to the number of risk factors per case. The T-score was compared between this groups using unpaired t-Student test...
December 2013: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/26051702/the-associations-between-environmental-quality-and-preterm-birth-in-the-united-states-2000-2005-a-cross-sectional-analysis
#19
Kristen M Rappazzo, Lynne C Messer, Jyotsna S Jagai, Christine L Gray, Shannon C Grabich, Danelle T Lobdell
BACKGROUND: Many environmental factors have been independently associated with preterm birth (PTB). However, exposure is not isolated to a single environmental factor, but rather to many positive and negative factors that co-occur. The environmental quality index (EQI), a measure of cumulative environmental exposure across all US counties from 2000-2005, was used to investigate associations between ambient environment and PTB. METHODS: With 2000-2005 birth data from the National Center for Health Statistics for the United States (n = 24,483,348), we estimated the association between increasing quintiles of the EQI and county-level and individual-level PTB; we also considered environmental domain-specific (air, water, land, sociodemographic and built environment) and urban-rural stratifications...
2015: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/26033076/impact-of-statin-therapy-on-mortality-in-patients-with-sepsis-associated-acute-respiratory-distress-syndrome-ards-depends-on-ards-severity-a-prospective-observational-cohort-study
#20
Ashham Mansur, Maximilian Steinau, Aron Frederik Popov, Michael Ghadimi, Tim Beissbarth, Martin Bauer, José Hinz
BACKGROUND: Previous investigations have presumed a potential therapeutic effect of statin therapy in patients with acute respiratory distress syndrome (ARDS). Statins are expected to attenuate inflammation in the lungs of patients with ARDS due to their anti-inflammatory effects. Clinical investigations of the role of statin therapy have revealed contradictory results. This study aimed to investigate whether pretreatment and continuous therapy with statins in patients with sepsis-associated ARDS are associated with 28-day survival according to disease severity (mild, moderate, or severe)...
2015: BMC Medicine
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