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Intracranial pressure monitors

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https://www.readbyqxmd.com/read/29766131/does-intracranial-pressure-management-hurt-more-than-it-helps-in-traumatic-brain-injury
#1
Charles A Adams, Deborah M Stein, Jonathan J Morrison, Thomas M Scalea
Traumatic brain injury (TBI) is the leading cause of death after traumatic injury. Raised intracranial pressure (ICP) is particularly associated with poor TBI outcomes, prompting clinicians to monitor this parameter, using it to guide therapies aimed at reducing pressures. Despite this approach being recommended by several bodies such as the Brain Trauma Foundation and the American College of Surgeons, the evidence demonstrating that ICP-guided therapy improves outcome is limited. The topic was debated at the 36th Annual Point/Counterpoint Acute Care Surgery Conference and the following article summarizes the discussants points of view along with a summary of the evidence...
2018: Trauma surgery & acute care open
https://www.readbyqxmd.com/read/29756534/neurostimulant-prescribing-patterns-in-children-admitted-to-the-icu-after-traumatic-brain-injury
#2
Amanda Marie Morrison, Amy Houtrow, James Zullo, Patrick M Kochanek, Carol Vetterly, Ericka L Fink
Neurostimulant medications are commonly prescribed following traumatic brain injury (TBI) in adults; little is known about their use in children with TBI. Our objective was to analyze neurostimulant prescribing practices from 2005 to 2015 in children admitted to the intensive care unit (ICU) with TBI. We hypothesized that neurostimulant prescriptions have increased over time and are associated with older age and injury severity. A retrospective cohort study of patients aged 1 month to 18 years with an ICD-9-CM discharge diagnosis code for TBI admitted to the ICU between 2005 and 2015 in 37 pediatric hospitals included in the Pediatric Health Information System was conducted...
May 14, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29751187/brain-trauma-foundation-guideline-compliance-results-of-a-multidisciplinary-international-survey
#3
Ryan Hirschi, Casey Rommel, Joshua Letsinger, Raminder Nirula, Gregory William John Hawryluk
BACKGROUND: The Brain Trauma Foundation (BTF) guidelines reflect evidence-based best practices in the management of traumatic brain injury (TBI) however compliance varies. OBJECTIVE: To inform self-reported physician compliance and predictors of compliance related to BTF guidelines via an international survey. METHODS: We conducted an international, multidisciplinary survey examining self-reported adherence to the BTF guidelines and multiple factors potentially affecting adherence...
May 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29749881/reversible-ventriculoperitoneal-shunt-dysfunction-and-chronic-constipation-case-report
#4
Barbara A Morais, Daniel D Cardeal, Fernanda G Andrade, Wellingson S Paiva, Hamilton Matushita, Manoel J Teixeira
Constipation can cause transient malfunction of the ventriculoperitoneal shunt (VPS). Patients with myelomeningocele or cerebral palsy are often diagnosed with hydrocephalus and constipation due to neurogenic bowel. These patients are more prone to VPS dysfunction, often requiring surgical revision. The authors report the case of a 6-year-old girl with a VPS that had been implanted due to hydrocephalus secondary to myelomeningocele. The patient was brought to the emergency department with intermittent headache, vomiting, constipation, and abdominal distension and pain...
May 11, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29744469/recent-progress-on-biodegradable-materials-and-transient-electronics
#5
REVIEW
Rongfeng Li, Liu Wang, Deying Kong, Lan Yin
Transient electronics (or biodegradable electronics) is an emerging technology whose key characteristic is an ability to dissolve, resorb, or physically disappear in physiological environments in a controlled manner. Potential applications include eco-friendly sensors, temporary biomedical implants, and data-secure hardware. Biodegradable electronics built with water-soluble, biocompatible active and passive materials can provide multifunctional operations for diagnostic and therapeutic purposes, such as monitoring intracranial pressure, identifying neural networks, assisting wound healing process, etc...
September 2018: Bioactive Materials
https://www.readbyqxmd.com/read/29732476/critical-thresholds-for-intracranial-pressure-vary-over-time-in-non-craniectomised-traumatic-brain-injury-patients
#6
Basil Nourallah, Frederick A Zeiler, Leanne Calviello, Peter Smielewski, Marek Czosnyka, David K Menon
BACKGROUND: Intracranial pressure (ICP)- and cerebral perfusion pressure (CPP)-guided therapy is central to neurocritical care for traumatic brain injury (TBI) patients. We sought to identify time-dependent critical thresholds for mortality and unfavourable outcome for ICP and CPP in non-craniectomised TBI patients. METHODS: This is a retrospective cohort study of 355 patients with moderate-to-severe TBI who received ICP monitoring and were managed without decompressive craniectomy in a tertiary hospital neurocritical care unit...
May 7, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29731820/multimodal-monitoring-combined-with-hypothermia-for-the-management-of-severe-traumatic-brain-injury-a-case-report
#7
Jun-Hui Chen, Yi-Nong Xu, Meng Ji, Pei-Pei Li, Li-Kun Yang, Yu-Hai Wang
Traumatic brain injury (TBI) is a prominent public health issue that has a significant negative impact on patients and their family members. It is the leading cause of mortality and disability among young (below 50 years old) individuals. Intracranial hypertension (ICH) remains the single most difficult therapeutic challenge for the management of severe TBI. Therapeutic hypothermia may reduce intracranial hypertension and improve patient outcomes; however, the use of hypothermia is controversial. It has been reported that therapeutic hypothermia elicits no therapeutic benefit for patients with TBI...
May 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29726988/validation-of-noninvasive-absolute-intracranial-pressure-measurements-in-traumatic-brain-injury-and-intracranial-hemorrhage
#8
Jenny C Kienzler, Rolandas Zakelis, Sabrina Bäbler, Elke Remonda, Arminas Ragauskas, Javier Fandino
BACKGROUND: Increased intracranial pressure (ICP) causes secondary damage in traumatic brain injury (TBI), and intracranial hemorrhage (ICH). Current methods of ICP monitoring require surgery and carry risks of complications. OBJECTIVE: To validate a new instrument for noninvasive ICP measurement by comparing values obtained from noninvasive measurements to those from commercial implantable devices through this pilot study. METHODS: The ophthalmic artery (OA) served as a natural ICP sensor...
May 3, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29725828/comparison-of-effect-of-dexmedetomidine-and-lidocaine-on-intracranial-and-systemic-hemodynamic-response-to-chest-physiotherapy-and-tracheal-suctioning-in-patients-with-severe-traumatic-brain-injury
#9
Shalendra Singh, Rajendra Singh Chouhan, Ashish Bindra, Nayani Radhakrishna
PURPOSE: Chest physiotherapy and tracheal suction cause sympathetic stimulation and increase heart rate (HR), mean arterial pressure (MAP) and intracranial pressure (ICP) which may have deleterious effect in the head injured. We planned to compare the effect of intravenous dexmedetomidine and lidocaine on intracerebral and systemic hemodynamic response to chest physiotherapy (CP) and tracheal suctioning (TS) in patients with severe traumatic brain injury (sTBI). METHODS: Prospective, randomized study in patients with sTBI, 18-60 years of age, undergoing mechanical ventilation and intraparenchymal ICP monitoring...
May 3, 2018: Journal of Anesthesia
https://www.readbyqxmd.com/read/29725178/bedside-ultrasonography-as-an-alternative-to-computed-tomography-scan-for-the-measurement-of-optic-nerve-sheath-diameter
#10
Uday Yanamandra, Amul Gupta, Sushma Yanamandra, Subrat Kumar Das, Sagarika Patyal, Velu Nair
Background: Optic nerve sheath diameter (ONSD) as measured by optic nerve sheath ultrasonography (ONSU) is used as a surrogate marker of intracranial pressure (ICP), especially in resource-limited settings. There is a growing interest in the use of ONSU in emergency and high-altitude setups. Notwithstanding multiple studies done on this subject, there is a paucity of data regarding standardization of techniques and comparison of ONSU with computed tomography (CT). Materials and Methods: Thirty-five patients with a diagnosis of high-altitude cerebral edema were enrolled in the study...
April 2018: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29722618/noninvasive-in-ear-monitoring-of-intracranial-pressure-during-microgravity-in-parabolic-flights
#11
Paul Avan, Herve Normand, Fabrice Giraudet, Gregory Gerenton, Pierre Denise
Among possible causes of visual impairment or headache experienced by astronauts in microgravity or post-flight and that hamper their performance, elevated intracranial pressure (ICP) has been invoked, but never measured for lack of non-invasive methods. The goal of this work was to test two noninvasive methods of ICP monitoring using in-ear detectors of ICP-dependent auditory responses, acoustic and electric, in acute microgravity afforded by parabolic flights. The devices detecting these responses were hand-held tablets routinely used in otolaryngology for hearing diagnosis, customized for ICP extraction and serviceable by unskilled operators...
May 3, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29717219/proteomic-differences-between-focal-and-diffuse-traumatic-brain-injury-in-human-brain-tissue
#12
Sami Abu Hamdeh, Ganna Shevchenko, Jia Mi, Sravani Musunuri, Jonas Bergquist, Niklas Marklund
The early molecular response to severe traumatic brain injury (TBI) was evaluated using biopsies of structurally normal-appearing cortex, obtained at location for intracranial pressure (ICP) monitoring, from 16 severe TBI patients. Mass spectrometry (MS; label free and stable isotope dimethyl labeling) quantitation proteomics showed a strikingly different molecular pattern in TBI in comparison to cortical biopsies from 11 idiopathic normal pressure hydrocephalus patients. Diffuse TBI showed increased expression of peptides related to neurodegeneration (Tau and Fascin, p < 0...
May 1, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29703901/cvd-grown-monolayer-mos-2-in-bioabsorbable-electronics-and-biosensors
#13
Xiang Chen, Yong Ju Park, Minpyo Kang, Seung-Kyun Kang, Jahyun Koo, Sachin M Shinde, Jiho Shin, Seunghyun Jeon, Gayoung Park, Ying Yan, Matthew R MacEwan, Wilson Z Ray, Kyung-Mi Lee, John A Rogers, Jong-Hyun Ahn
Transient electronics represents an emerging technology whose defining feature is an ability to dissolve, disintegrate or otherwise physically disappear in a controlled manner. Envisioned applications include resorbable/degradable biomedical implants, hardware-secure memory devices, and zero-impact environmental sensors. 2D materials may have essential roles in these systems due to their unique mechanical, thermal, electrical, and optical properties. Here, we study the bioabsorption of CVD-grown monolayer MoS2 , including long-term cytotoxicity and immunological biocompatibility evaluations in biofluids and tissues of live animal models...
April 27, 2018: Nature Communications
https://www.readbyqxmd.com/read/29703787/dissociation-between-csd-evoked-metabolic-perturbations-and-meningeal-afferent-activation-and-sensitization-implications-for-mechanisms-of-migraine-headache-onset
#14
Jun Zhao, Dan Levy
The onset of the headache phase during attacks of migraine with aura, which occur in about 30% of migraineurs, is believed to involve cortical spreading depression (CSD) and the ensuing activation and sensitization of primary afferent neurons that innervate the intracranial meninges, and their related large vessels. The mechanism by which CSD enhances the activity and mechanosensitivity of meningeal afferents remains poorly understood, but may involve cortical metabolic perturbations. We employed extracellular single-unit recording of meningeal afferent activity and monitored changes in cortical blood flow and tissue partial pressure of oxygen (tpO2 ) in anesthetized male rats to test whether the prolonged cortical hypoperfusion and reduction in tissue oxygenation that occur in the wake of CSD contribute to meningeal nociception...
April 27, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29696505/intracranial-pressure-monitoring-in-diffuse-brain-injury-why-the-developing-world-needs-it-more
#15
Tarang K Vora, Sudish Karunakaran, Ajay Kumar, Anil Chiluka, Harish Srinivasan, Kanishk Parmar, Srivatsan Thirumalai Vasu, Rahul Srinivasan, H A Chandan, P S Vishnu, Lakshay Raheja
BACKGROUND: Use of ICP monitoring is considered to be part of "standard of care" in management of severe traumatic brain injury, but it is rarely used in developing countries. The authors present a study which evaluates the efficacy and outcomes of ICP monitoring at a high-volume trauma center in India. METHODS: Data on management and outcomes for 126 patients who were admitted with diffuse traumatic brain injury (GCS 3-8) were studied prospectively over an 18-month period...
June 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29665012/wavelet-pressure-reactivity-index-a-validation-study
#16
Xiuyun Liu, Marek Czosnyka, Joseph Donnelly, Danilo Cardim, Manuel Cabeleira, Peter J Hutchinson, Xiao Hu, Peter Smielewski, Ken Brady
KEY POINTS: The brain is vulnerable to damage from too little or too much blood flow. A physiological mechanism called cerebral autoregulation (CA) exists to maintain stable blood flow even if cerebral perfusion pressure (CPP) is changing. A robust method for assessing CA is not yet available. There are still some problems with the traditional measure, the pressure reactivity index (PRx). We introduced a new method, wavelet transform method (wPRx) to assess CA using data from two sets of controlled hypotension experiments in piglets: One set with artificially manipulated ABP oscillations; the other group were spontaneous ABP waves...
April 17, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29648985/feasibility-of-telemetric-intracranial-pressure-monitoring-in-the-neuro-intensive-care-unit
#17
Alexander Lilja-Cyron, Jesper Kelsen, Morten Andresen, Kåre Fugleholm, Marianne Juhler
Intracranial pressure (ICP) monitoring is crucial in the management of acute neurosurgical conditions such as traumatic brain injury (TBI). However, pathological ICP may persist beyond the admission to the neuro intensive care unit (NICU). We investigated the feasibility of telemetric ICP monitoring in the NICU, as this technology provides the possibility of long-term ICP assessment beyond NICU discharge. In this prospective investigation, we implanted telemetric ICP sensors (Raumedic Neurovent-P-tel) instead of conventional, cabled ICP sensors in patients undergoing decompressive craniectomy...
May 3, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29621117/cerebral-multimodal-monitoring-in-sepsis-an-experimental-study
#18
Pedro Kurtz, Joana C d'Avila, Darwin Prado, Caroline Madeira, Charles Vargas-Lopes, Rogerio Panizzutti, Luciano Cesar Pontes Azevedo, Fernando A Bozza
Acute brain dysfunction is a complication of sepsis and its pathophysiology remains poorly understood. We studied the brain metabolism in a resuscitated animal model of sepsis. Twelve anesthetized, mechanically ventilated and invasively monitored pigs were allocated to a sham procedure (N = 5) or sepsis (N = 7). Sepsis was induced through fecal inoculation in the peritoneum. Fluid resuscitation was maintained during the entire study period. Animals were observed until spontaneous death or for a maximum of 24 hours...
April 4, 2018: Shock
https://www.readbyqxmd.com/read/29618106/contribution-of-intrasellar-pressure-elevation-to-headache-manifestation-in-pituitary-adenoma-evaluated-with-intraoperative-pressure-measurement
#19
Yasuhiko Hayashi, Yasuo Sasagawa, Masahiro Oishi, Daisuke Kita, Koichi Misaki, Issei Fukui, Osamu Tachibana, Mitsutoshi Nakada
BACKGROUND: Headache frequently occurs in patients with pituitary adenoma and is reported in large as well as small adenomas. However, the exact mechanism of headache derived from pituitary adenoma remains unknown. OBJECTIVE: To evaluate the contribution of intrasellar pressure (ISP) to headache manifestation by using intraoperative ISP measurement. METHODS: The records of 108 patients who had first-time transsphenoidal surgery for pituitary adenoma were reviewed retrospectively...
March 29, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29597018/rare-event-captured-with-an-icp-monitor-malignant-spike-in-intracranial-pressure-during-delayed-chest-closure-in-heart-transplant-patient-with-an-ischemic-stroke
#20
Katherine Berry, Evan M Luther, Timur Urakov, Ross Bullock
No abstract text is available yet for this article.
March 26, 2018: World Neurosurgery
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