keyword
MENU ▼
Read by QxMD icon Read
search

BSAC

keyword
https://www.readbyqxmd.com/read/29228202/activity-of-ceftazidime-avibactam-against-problem-enterobacteriaceae-and-pseudomonas-aeruginosa-in-the-uk-2015-16
#1
David M Livermore, Danièle Meunier, Katie L Hopkins, Michel Doumith, Robert Hill, Rachel Pike, Peter Staves, Neil Woodford
Background: Ceftazidime/avibactam combines an established oxyimino-cephalosporin with the first diazabicyclooctane β-lactamase inhibitor to enter clinical use. We reviewed its activity against Gram-negative isolates, predominantly from the UK, referred for resistance investigation in the first year of routine testing, beginning in July 2015. Methods: Isolates were as received from referring laboratories; there is a bias to submit those with suspected carbapenem resistance...
December 8, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29171572/susceptibility-pattern-of-methicillin-resistant-staphylococcus-aureus-to-vancomycin-and-other-alternate-agents-report-from-a-private-sector-hospital-laboratory
#2
Faryal Saleem, Naima Fasih, Afia Zafar
With increasing prevalence of methicillin resistant Staphylococcus aureus in clinical settings and injudicious use of antibiotics, resistance among MRSA against commonly used antibiotics is increasing. To assess the susceptibility pattern of MRSA against vancomycin, linezolid, tigecycline, rifampicin, fosfomycin fusidic acid, clindamycin, trimethoprim-sulfamethoxazole and teicoplanin, minimum inhibitory concentrations (MICs) for given antimicrobials were performed on 234 MRSA clinical isolates using automated VITEK 2 system...
November 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/29091185/genomic-sequences-of-streptococcus-agalactiae-with-high-level-gentamicin-resistance-collected-in-the-bsac-bacteraemia-surveillance
#3
Michel Doumith, Shazad Mushtaq, Veronique Martin, Aiysha Chaudhry, Rachael Adkin, Juliana Coelho, Vicki Chalker, Alasdair MacGowan, Neil Woodford, David M Livermore
Background: Like other streptococci, Streptococcus agalactiae typically has intrinsic low-level aminoglycoside resistance. High-level gentamicin resistance was seen in 2 of 1125 isolates collected in the BSAC Bacteraemia Surveillance Programme between 2001 and 2014. These organisms, both isolated in 2014, were characterized. Methods: Identifications were by latex agglutination, MICs by BSAC agar dilution and sequencing by Illumina methodology. Results: Gentamicin MICs were >1024 mg/L versus a species mode of 8 mg/L; both isolates also were unusually ciprofloxacin resistant with MICs of 64 mg/L versus a species mode of 1 mg/L...
October 1, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29033302/the-antimicrobial-susceptibility-of-helicobacter-pylori-in-strains-isolated-from-children-in-israel
#4
Nina Pastukh, Avi Peretz, Diana Brodsky, Natlya Isakovich, Maya Azrad, Avi On
BACKGROUND: Helicobacter pylori is a pathogen that causes inflammation in the gastric mucosa, and may lead to a peptic ulcer, perforation, or malignancy. Children are at risk of contracting H. pylori and developing subsequent morbidity. In children, diagnosis and management are difficult and merit a different approach than with adults. OBJECTIVE: To describe resistance rates of H. pylori to antibiotics such as amoxicillin, tetracycline, clarithromycin, metronidazole, levofloxacin, and Rifampicin...
October 12, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28840351/activity-of-temocillin-and-15-other-agents-including-fosfomycin-and-colistin-against-enterobacteriaceae-in-hong-kong
#5
Margaret Ip, Christopher K Lai, Kitty S C Fung, K-Tak Wong, Chendi Zhu, Sebastien Van de Velde, Dominic N Tsang, Peter Hawkey
Limited data are available on temocillin susceptibilities in Enterobacteriaceae from Asian countries where antimicrobial resistance is prevalent. The in vitro activities of temocillin and 15 commonly used antimicrobials against 613 non-duplicate blood (n = 310) and urine (with clinically significant bacteriuria; n = 303) isolates of Enterobacteriaceae from patients who attended 3 out of 7 clusters of public hospitals of the Hospital Authority, Hong Kong, during 2015/2016 were tested. Minimum inhibitory concentrations (MICs) were determined by Clinical and Laboratory Standards Institute (CLSI) microbroth dilution (agar dilution with fosfomycin)...
August 25, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28791570/evaluation-of-migration-of-heavy-metals-and-performance-of-product-during-co-pyrolysis-process-of-municipal-sewage-sludge-and-walnut-shell
#6
Yucheng Liu, Qian Liu, Mingyan Chen, Lili Ma, Bing Yang, Ju Chen, Zhongxiang Lv, Qingling Liang, Ping Yang
A feasible and efficient type of biological sludge-activated carbon (BSAC) was produced by co-pyrolysis of municipal sewage sludge (MSS) and walnut shell (4:1, w/w) at 500 °C. It was found that BSAC was typical mesoporous material with favorable pore structure and abundant surface functional groups, whose performance was improved compared with conventional sludge-activated carbon (CSAC), combined with walnut shell-activated carbon (WSAC). The migration and transformation behavior of heavy metals (Zn, Cu, Ni, Cd, and Cr) in raw material after co-pyrolysis process were investigated...
September 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28668698/aggregatibacter-actinomycetemcomitans-serotype-prevalence-and-antibiotic-resistance-in-a-uk-population-with-periodontitis
#7
Chaido Akrivopoulou, Ingrid M Green, Nikolaos Donos, Sean P Nair, Derren Ready
OBJECTIVES: Aggregatibacter actinomycetemcomitans is a recognised pathogen involved in aggressive periodontitis. Seven serotypes of A. actinomycetemcomitans exist with a range of virulence and distribution dependent on ethnicity and geography. The ability of A. actinomycetemcomitans to invade soft tissue can necessitate the use of systemic antibiotics for treatment, however variations in its antibiotic susceptibility exist dependent on geographical location. METHODS: Serotypes of A...
September 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28637307/sparing-carbapenem-usage
#8
A Peter R Wilson
Background: Carbapenem resistance in Gram-negative bacteria is increasing in many countries and use of carbapenems and antibiotics to which resistance is linked should be reduced to slow its emergence. There are no directly equivalent antibiotics and the alternatives are less well supported by clinical trials. The few new agents are expensive. Objectives: To provide guidance on strategies to reduce carbapenem usage. Methods: A literature review was performed as described in the BSAC/HIS/BIA/IPS Joint Working Party on Multiresistant Gram-negative Infection Report...
September 1, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28520867/activity-of-ceftolozane-tazobactam-against-surveillance-and-problem-enterobacteriaceae-pseudomonas-aeruginosa-and-non-fermenters-from-the-british-isles
#9
David M Livermore, Shazad Mushtaq, Daniele Meunier, Katie L Hopkins, Robert Hill, Rachael Adkin, Aiysha Chaudhry, Rachel Pike, Peter Staves, Neil Woodford
Background: We assessed the activity of ceftolozane/tazobactam against consecutive isolates collected in the BSAC Bacteraemia Surveillance from 2011 to 2015 and against 'problem' isolates sent to the UK national reference laboratory from July 2015, when routine testing began. Methods: Susceptibility testing was by BSAC agar dilution with resistance mechanisms identified by PCR and interpretive reading. Results: Data were reviewed for 6080 BSAC surveillance isolates and 5473 referred organisms...
August 1, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28124956/-investigation-of-the-frequency-and-distribution-of-beta-lactamase-genes-in-the-clinical-isolates-of-acinetobacter-baumannii-collected-from-different-regions-of-turkey-a-multicenter-study
#10
MULTICENTER STUDY
Fatih Şaban Beriş, Emine Esra Budak, Duygu Gülek, Aytül Uzun, Zeynep Çizmeci, Fırat Zafer Mengeloğlu, Şahin Direkel, Yeliz Çetinkol, Yasemin Ay Altıntop, Meryem Iraz, Tuba Dal, Safiye Umut Say Coşkun, Pervin Özlem Balcı, Tuba Kayman, Ahmet Çalışkan, Yelda Yazıcı, İsmail Tosun, Ayşe Ertürk, Ayşegül Çopur Çiçek
The diversity and distribution of TEM, SHV and CTX-M type of extended-spectrum beta-lactamases (ESBLs) are important for the treatment and control of infections. Determination of ESBL genes in clinical isolates by polymerase chain reaction (PCR) and DNA sequencing can obtain useful data for their molecular epidemiology and risk. The aim of this study was to investigate the frequency of beta-lactamase genes in Acinetobacter baumannii strains isolated from different regions of Turkey. A total of 519 A.baumannii strains collected from hospitals located at 12 different provinces of Turkey (Bolu (n= 67), Tokat (n= 47), Trabzon (n= 25), Ordu (n= 27), Diyarbakır (n= 47), Niğde (n=31), Kayseri (n= 36), Ankara (n= 41), Kirikkale (n= 26), Kahramanmaraş (n= 25), Mersin (n= 40), Istanbul (n= 107)] between 2011-2012 period were included in the study...
October 2016: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28073969/characterization-of-carbapenemase-producing-enterobacteriaceae-in-the-west-midlands-region-of-england-2007-14
#11
Jacqueline Findlay, Katie L Hopkins, Adela Alvarez-Buylla, Daniéle Meunier, Nazim Mustafa, Robert Hill, Rachel Pike, Li-Xu McCrae, Peter M Hawkey, Neil Woodford
Objectives: Carbapenemase-producing Enterobacteriaceae (CPE) have been increasingly reported in the UK since 2003. We analysed patient and isolate data for CPE confirmed by the national reference laboratory from laboratories in the West Midlands region from November 2007 to December 2014. Methods: MICs were determined by BSAC agar dilution methodology and isolates exhibiting resistance to one or more carbapenems were screened for carbapenemase genes by PCR. Plasmid analyses were performed after electro-transformation of carbapenemase-encoding plasmids...
April 1, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28073966/extended-stability-of-antimicrobial-agents-in-administration-devices
#12
REVIEW
Abi Jenkins, Tim Hills, Mark Santillo, Mark Gilchrist
Background: Outpatient parenteral antimicrobial therapy (OPAT) is an established approach to patient care. A lack of data on antimicrobial stability within administration devices is a barrier to service expansion, and poses an antimicrobial stewardship dilemma. Often broad-spectrum, long half-life agents are used instead of narrow-spectrum agents, which need more frequent administration, but could possibly be used if stability data were available. Objectives: To complete a comprehensive literature review of published antimicrobial stability data, and assess these against a nationally recognized minimum dataset for medicines compounded into administration devices...
April 1, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28006650/rise-of-multidrug-resistant-non-vaccine-serotype-15a-streptococcus-pneumoniae-in-the-united-kingdom-2001-to-2014
#13
Carmen Sheppard, Norman K Fry, Shazad Mushtaq, Neil Woodford, Rosy Reynolds, Regina Janes, Rachel Pike, Robert Hill, Maimuna Kimuli, Peter Staves, Michel Doumith, Timothy Harrison, David M Livermore
Conjugate vaccines have reduced pneumococcal disease in vaccinated children and unvaccinated adults, but non-vaccine serotypes are of concern, particularly if antibiotic resistant. We reviewed Streptococcus pneumoniae collected via: (i) the British Society for Antimicrobial Chemotherapy (BSAC) surveillances from 2001-2014; (ii) Public Health England's (PHE) invasive isolate surveillance from 2005-2014 and (iii) referral to PHE for resistance investigation from 2005-2014. Serotype 15A increased in all series, with many representatives showing triple resistance to macrolides, tetracyclines and penicillin...
December 15, 2016: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/27999053/issues-in-antifungal-stewardship-an-opportunity-that-should-not-be-lost
#14
Chand Wattal, Arunaloke Chakrabarti, Jaswinder Kaur Oberoi, J Peter Donnelly, Rosemary A Barnes, B L Sherwal, Neeraj Goel, Sonal Saxena, George M Varghese, Rajeev Soman, Poonam Loomba, Bansidhar Tarai, Sanjay Singhal, Naimish Mehta, V Ramasubramanian, Dharma Choudhary, Yatin Mehta, Supradip Ghosh, Sumathi Muralidhar, Ravinder Kaur
Many countries have observed an increase in the incidence of invasive fungal infections (IFIs) over the past two decades with emergence of new risk factors and isolation of new fungal pathogens. Early diagnosis and appropriate antifungal treatment remain the cornerstones of successful outcomes. However, due to non-specific clinical presentations and limited availability of rapid diagnostic tests, in more than half of cases antifungal treatment is inappropriate. As a result, the emergence of antifungal resistance both in yeasts and mycelial fungi is becoming increasingly common...
April 1, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27724873/antimicrobial-susceptibility-testing-of-neisseria-gonorrhoeae-isolates-in-pakistan-by-etest-compared-to-calibrated-dichotomous-sensitivity-and-clinical-laboratory-standards-institute-disc-diffusion-techniques
#15
COMPARATIVE STUDY
Pushpa Bhawan Mal, Kauser Jabeen, Joveria Farooqi, Magnus Unemo, Erum Khan
BACKGROUND: Accurate detection of Neisseria gonorrhoeae antimicrobial resistance is essential for appropriate management and prevention of spread of infection in the community. In this study Calibrated Dichotomous Sensitivity (CDS) and Clinical Laboratory Standards Institute (CLSI) disc diffusion methods were compared with minimum inhibitory concentration (MIC) by Etest in Neisseria gonorrhoeae isolates from Karachi, Pakistan. CDS and CLSI disc diffusion techniques, and Etest for ceftriaxone, penicillin G, spectinomycin and ciprofloxacin against 100 isolates from years 2012-2014 were performed...
October 10, 2016: BMC Microbiology
https://www.readbyqxmd.com/read/27530859/multidrug-resistant-staphylococcus-haemolyticus-isolates-from-infected-eyes-and-healthy-conjunctivae-in-india
#16
Sasmita Panda, Sarita Kar, Savitri Sharma, Durg V Singh
This study aimed to determine the presence of antibiotic resistance genes (ARGs), SCCmec elements and genetic relatedness among Staphylococcus haemolyticus isolated from patients with a variety of eye infections (n=11) and from healthy conjunctiva (n=7). Minimum inhibitory concentrations were determined for 14 antimicrobials according to BSAC guidelines. PCR was used to identify the presence of mecA, mecC, SCCmec type and ARGs. Sequencing was used to determine mutations in gyrA, gyrB, topoisomerase IVA and IVB genes...
September 2016: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/27530786/-prevalence-of-moraxella-catarrhalis-in-the-nasopharyngeal-specimen-from-1%C3%A2-082-hospitalized-children-with-respiratory-infection-and-the-drug-resistance-of-the-isolates
#17
Ping Tang, Wei Shi, Hai-Ling Zeng, Wei Ding, Cheng Wang, Kai-Hu Yao, De-Nian Wen
OBJECTIVE: To investigate the prevalence of Moraxella catarrhalis in the nasopharyngeal region of children with respiratory infection and the sensitivity of Moraxella catarrhalis isolates to common antimicrobial drugs. METHODS: Nasopharyngeal swabs were collected from 1 082 children with respiratory infection, and Moraxella catarrhalis strains were isolated. The E-test method and disc diffusion test were used to determine the sensitivity of these strains to 11 common antimicrobial drugs...
August 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/27494904/amikacin-use-and-therapeutic-drug-monitoring-in-adults-do-dose-regimens-and-drug-exposures-affect-either-outcome-or-adverse-events-a-systematic-review
#18
REVIEW
Abi Jenkins, Alison H Thomson, Nicholas M Brown, Yvonne Semple, Christine Sluman, Alasdair MacGowan, Andrew M Lovering, Phil J Wiffen
OBJECTIVES: The objectives of this study were to identify the amikacin dosage regimens and drug concentrations consistent with good outcomes and to determine the drug exposures related to nephrotoxicity and ototoxicity. METHODS: A literature review was conducted in Medline, EMBASE and the Cochrane Central Register of Controlled Trials. Full journal articles reporting randomized controlled trials, controlled clinical trials, interrupted time series trials, and controlled before and after studies involving amikacin therapeutic drug monitoring (TDM) and dose adjustment were considered for inclusion...
October 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27180331/behind-the-scenes-of-jac-the-british-society-for-antimicrobial-chemotherapy
#19
REVIEW
Tracey Guise, Dilip Nathwani
This brief article describes the relationship between the British Society for Antimicrobial Chemotherapy (BSAC) and JAC, and how JAC has directly and indirectly facilitated delivery of the BSAC's charitable objectives over the past 40 years.
2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27150395/population-structure-of-escherichia-coli-causing-bacteraemia-in-the-uk-and-ireland-between-2001-and-2010
#20
M J Day, M Doumith, J Abernethy, R Hope, R Reynolds, J Wain, D M Livermore, N Woodford
OBJECTIVES: Escherichia coli is the most common agent of bacteraemia, bacterial gastroenteritis and urinary tract infections (UTIs). Lineages causing UTIs and gastrointestinal disease are well defined, but less is known about those causing bacteraemia. We therefore investigated the population structure of E. coli from bacteraemia in the UK and Ireland between 2001 and 2010. METHODS: E. coli isolates (n = 2166) were submitted to the BSAC Bacteraemia Surveillance Programme from 18 UK and Irish centres from 2001 to 2010...
August 2016: Journal of Antimicrobial Chemotherapy
keyword
keyword
86696
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"